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公开(公告)号：US11517718B2
公开(公告)日：2022-12-06
申请号：US16870790
申请日：2020-05-08
Applicant: Edwards Lifesciences Corporation
Inventor： Matthew T. Winston , Christopher J. Olson , Asher L. Metchik , Tri D. Tran , Alexander J. Siegel
Abstract: A delivery apparatus includes a steerable shaft having a pull-wire conduit. A pull wire extends through the pull-wire conduit. The steerable shaft includes one or more layers. A compression-resistance portion is incorporated into at least one of the one or more layers. A cross-section of the compression-resistance portion has an arcuate shape that extends along a portion of a cross-section of the steerable shaft. The compression-resistance portion has a hardness that is greater than a hardness of the one or more layers that the compression-resistance portion is incorporated into.
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公开(公告)号：US20210059813A1
公开(公告)日：2021-03-04
申请号：US17096641
申请日：2020-11-12
Applicant: Edwards Lifesciences Corporation
Inventor： David M. Taylor , Alexander J. Siegel , Thomas V. Doherty , Christopher J. Olson , Yoon Hee Kwon
Abstract: In a representative embodiment, a method comprises implanting first and second inflatable bodies within an annulus of a native heart valve by securing the inflatable bodies to tissue of the native heart valve with sutures, and implanting a prosthetic heart valve between the inflatable bodies such that the prosthetic heart valve is retained within the annulus by the inflatable bodies.
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公开(公告)号：US20180325663A1
公开(公告)日：2018-11-15
申请号：US15976415
申请日：2018-05-10
Applicant: Edwards Lifesciences Corporation
Inventor： David M. Taylor , Alexander J. Siegel , Thomas V. Doherty , Christopher J. Olson , Yoon H. Kwon
CPC classification number: A61F2/2418 , A61F2/2463 , A61F2210/0014 , A61F2210/0085 , A61F2220/0008 , A61F2230/0023 , A61F2230/0026 , A61F2250/0003 , A61F2250/0013 , A61L27/18 , A61L2400/06
Abstract: In a representative embodiment, an implantable assembly for a native heart valve comprises a prosthetic heart valve and first and second inflatable bodies. The prosthetic heart valve can comprise a frame and prosthetic leaflets. The first inflatable body can comprise first and second end portions, wherein the first end portion is configured to be secured to tissue of the native heart valve at a first location, and the second end portion is configured to engage an outer surface of the prosthetic valve. The second inflatable body can comprise third and fourth end portions, wherein the third end portion is configured to be secured to tissue of the native heart valve at a second location, and the fourth end portion is configured to engage the outer surface of the prosthetic valve. The first and second inflatable bodies anchor the prosthetic valve within the annulus of the native heart valve.
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公开(公告)号：US20160331523A1
公开(公告)日：2016-11-17
申请号：US15154578
申请日：2016-05-13
Applicant: Edwards Lifesciences Corporation
Inventor： Mark Chau , David M. Taylor , Alexander J. Siegel , Christopher J. Olson , Sergio Delgado , Alexander H. Cooper , Lauren R. Freschauf , Asher L. Metchik , Matthew T. Winston , Cristobal R. Hernandez , Emil Karapetian , Bao Khuu , Eric Dixon
IPC: A61F2/24
Abstract: In one representative embodiment, an implantable prosthetic device comprises a spacer body portion configured to be disposed between native leaflets of a heart, and an anchor portion configured to secure the native leaflets against the spacer body portion, wherein the prosthetic device is movable between a compressed configuration, in which the spacer body portion is radially compressed and is axially spaced relative to the anchor portion, and an expanded configuration, in which the spacer body portion expands radially outwardly relative to the compressed configuration and overlaps at least a portion of the anchor portion.
Abstract translation: 在一个代表性的实施例中，可植入假体装置包括被配置为设置在心脏的天然传播单元之间的间隔体本体部分和被配置成将天然传单固定在间隔体主体部分上的锚固部分，其中假体装置可在压缩 配置，其中间隔件主体部分被径向压缩并且相对于锚定部分轴向间隔开，并且展开构造，其中间隔件主体部分相对于压缩构造径向向外扩张并且与锚定部分的至少一部分重叠 。
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公开(公告)号：US20160228240A1
公开(公告)日：2016-08-11
申请号：US15130402
申请日：2016-04-15
Applicant: Edwards Lifesciences Corporation
Inventor： Christopher J. Olson , Glen Thomas Rabito , Dustin P. Armer , Minh T. Ma , Devin H. Marr , Cheng-Tung Huang , Hiroshi Okabe , Kevin M. Stewart , Alison S. Curtis , Philip P. Corso, JR.
IPC: A61F2/24
CPC classification number: A61F2/243 , A61F2/2418 , A61F2/2427 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2220/0016 , A61F2220/005 , A61F2220/0075 , A61F2230/0054 , A61F2230/0076 , A61F2250/006
Abstract: Disclosed herein are representative embodiments of methods, apparatus, and systems used to deliver a prosthetic heart valve to a deficient valve. In one embodiment, for instance, a support structure and an expandable prosthetic valve are advanced through the aortic arch of a patient using a delivery system. The support structure is delivered to a position on or adjacent to the surface of the outflow side of the aortic valve (the support structure defining a support-structure interior). The expandable prosthetic valve is delivered into the aortic valve and into the support-structure interior. The expandable prosthetic heart valve is expanded while the expandable prosthetic heart valve is in the support-structure interior and while the support structure is at the position on or adjacent to the surface of the outflow side of the aortic valve, thereby causing one or more native leaflets of the aortic valve to be frictionally secured between the support structure and the expanded prosthetic heart valve.
Abstract translation: 这里公开了用于将假性心脏瓣膜递送到缺陷阀的方法，装置和系统的代表性实施例。 在一个实施例中，例如，支撑结构和可扩张的假体瓣膜通过使用递送系统的患者的主动脉弓前进。 支撑结构被传送到主动脉瓣（支撑结构限定支撑结构内部）的流出侧的表面上或邻近的位置。 可膨胀假体瓣膜被输送到主动脉瓣并进入支撑结构内部。 可扩张假体心脏瓣膜膨胀，而可扩张假体心脏瓣膜处于支撑结构内部，而支撑结构处于主动脉瓣的流出侧表面上或邻近主动脉瓣的流出侧的位置，从而导致一个或多个本机 主动脉瓣的小叶被摩擦地固定在支撑结构和扩张的假体心脏瓣膜之间。
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Patent Agency Ranking
公开(公告)号：US20250090808A1
公开(公告)日：2025-03-20
申请号：US18961981
申请日：2024-11-27
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Matthew T. Winston , Christopher J. Olson , Asher L. Metchik , Tri D. Tran , Alexander J. Siegel
Abstract: A steerable catheter includes a shaft and a pull wire. The shaft includes a proximal portion and a distal portion. The shaft includes an inner layer that defines an inner lumen of the shaft. The shaft comprises an outer layer that defines an outer diameter of the shaft. The shaft comprises a pull-wire lumen between the inner layer and the outer layer. The pull wire extends through the pull-wire lumen. The pull wire has a proximal end portion and a distal end portion. The distal end portion of the pull wire is fixed to the distal portion of the shaft. The proximal end portion of the pull wire extends radially outward of the outer layer. Increasing tension in the pull wire curves the distal portion of the shaft.
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公开(公告)号：US12178973B2
公开(公告)日：2024-12-31
申请号：US17992427
申请日：2022-11-22
Applicant: Edwards Lifesciences Corporation
Inventor： Matthew T. Winston , Christopher J. Olson , Asher L. Metchik , Tri D. Tran , Alexander J. Siegel
Abstract: A delivery apparatus includes a steerable guide sheath. The steerable guide sheath has a steerable portion, a pull ring located in the distal portion, and a pull wire coupled at one end to the pull ring and coupled at the opposite end to a control handle. The pull wire extends longitudinally through a pull-wire conduit. The steerable guide sheath further includes a compression-resistance portion made of metal and located in the distal portion.
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公开(公告)号：US20240261098A1
公开(公告)日：2024-08-08
申请号：US18625047
申请日：2024-04-02
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Christopher J. Olson , Glen T. Rabito , Dustin P. Armer , Minh T. Ma , Devin H. Marr , Cheng-Tung Huang , Hiroshi Okabe , Kevin M. Stewart , Alison S. Curtis , Philip P. Corso, JR.
IPC: A61F2/24
CPC classification number: A61F2/2439 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/2427 , A61F2220/0016 , A61F2220/005 , A61F2220/0075 , A61F2230/0054 , A61F2230/0076 , A61F2250/006
Abstract: Prosthetic heart valve assemblies and methods, apparatus, and systems used to deliver a prosthetic heart valve assembly. A prosthetic heart valve assembly includes an inner frame, a prosthetic leaflet section disposed within the inner frame extending between in inflow row of cells and an outflow row of cells of the inner frame, and an outer support stent. The inner frame is disposed within the outer support stent, and the outer support stent is coupled and/or fastened to the inner frame. The outer support stent includes a plurality leaflet capturing arms for capturing native leaflets between the leaflet capturing arms and a portion of the prosthetic heart valve assembly when the prosthetic heart valve assembly is implanted in a native valve. For example, the native leaflets can be frictionally secured between the leaflet capturing arms of the support stent and the inner frame.
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公开(公告)号：US11793642B2
公开(公告)日：2023-10-24
申请号：US16522600
申请日：2019-07-25
Applicant: Edwards Lifesciences Corporation
Inventor： Mark Chau , David M. Taylor , Alexander J. Siegel , Christopher J. Olson , Sergio Delgado , Alexander H. Cooper , Lauren R. Freschauf , Asher L. Metchik , Matthew T. Winston , Cristobal R. Hernandez , Emil Karapetian , Bao Khuu , Eric Robert Dixon
IPC: A61F2/24
CPC classification number: A61F2/246 , A61F2/2454 , A61F2/2463 , A61F2/2466 , A61F2220/0016 , A61F2310/00023
Abstract: In one representative embodiment, an implantable prosthetic device comprises a spacer body portion configured to be disposed between native leaflets of a heart, and an anchor portion configured to secure the native leaflets against the spacer body portion. The prosthetic device can be movable between multiple configurations. The spacer body can be made from braided, self-expandable metallic thread. A delivery apparatus can have a first shaft and a second shaft, wherein movement of the first shaft relative to the second shaft moves the anchor portion relative to the spacer body.
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公开(公告)号：US20230190469A1
公开(公告)日：2023-06-22
申请号：US18172806
申请日：2023-02-22
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Emil Karapetian , Maria Charles Vija Stanislaus , Gregory Bak-Boychuk , Christopher J. Olson , Cristobal R. Hernandez , William C. Brunnett , Netanel Benichou , Lauren R. Freschauf , Alexander J. Siegel , Stanton J. Rowe , Alison S. Curtis
CPC classification number: A61F2/246 , A61F2/2466 , A61F2/2409 , A61F2/88 , A61F2/07 , A61F2/2436 , A61F2/2454 , A61F2/2427 , A61F2/2418 , A61F2002/825
Abstract: This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In a representative embodiment, a support frame configured to be implanted in a heart valve comprises a main body formed by formed by a plurality of inner members forming an inner clover and a plurality of outer members forming an outer clover. The support frame can include gaps located between inner members of the plurality of inner members and outer members of the plurality of outer members. The inner clover can be radially inside the outer clover, and the outer clover can have larger dimensions than the inner clover. The support frames herein can be radially expandable and collapsible.
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