中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

127 records (took 0.044 seconds)

    Homogenous assay (II)
    11.
    发明授权
    Homogenous assay (II) 有权

    公开(公告)号：US11567066B2

    公开(公告)日：2023-01-31

    申请号：US17478595

    申请日：2021-09-17

    Applicant: Essenlix Corporation

    Inventor： Stephen Y. Chou ,  Wei Ding ,  Ji Li ,  Yufan Zhang

    IPC: G01N33/543 ,  C12Q1/6804 ,  C12Q1/6869 ,  G06V20/69

    Abstract: Among other things, the present disclosure is related to devices and methods of performing biological and chemical assays, such as but not limited to immunoassays and nucleic assay acid, particularly a homogeneous assay that does not use a wash step and that is fast (e.g., 60 seconds from dropping a sample to displaying results). The present disclosure is related to both competitive and non-competitive homogeneous assays.

    Nucleic acid hybridization assay
    13.
    发明授权
    Nucleic acid hybridization assay 有权

    公开(公告)号：US11408028B2

    公开(公告)日：2022-08-09

    申请号：US16483833

    申请日：2018-02-08

    Applicant: Essenlix Corporation

    Inventor： Stephen Y. Chou ,  Wei Ding ,  Ji Qi ,  Yufan Zhang ,  Ji Li

    IPC: C12Q1/68 ,  C12Q1/6837 ,  B01L3/00 ,  B01L7/00 ,  C12Q1/686 ,  G01N21/65

    Abstract: Provided herein is a method and device for performing a homogeneous nucleic acid detection assay. The device can contain a pair of plates where one of the plates comprises (i) surface amplification surface; and (ii) target-specific nucleic acid probes that are immobilized on said amplification surface and that specifically binds to a part of the target nucleic acid; and the second plate comprises a sample contact area comprising a reagent storage site that comprises target-specific nucleic acid detection agents that specifically binds to another part of the target nucleic acid. In some embodiments, the device can be read without a washing unbound label from the surface of the device.

    Methods and devices for correlating a biomarker in a non-blood bodily fluid with the biomarker in blood
    15.
    发明授权
    Methods and devices for correlating a biomarker in a non-blood bodily fluid with the biomarker in blood 有权

    公开(公告)号：US11353446B2

    公开(公告)日：2022-06-07

    申请号：US17433092

    申请日：2020-11-06

    Applicant: Essenlix Corporation

    Inventor： Stephen Y. Chou ,  Wei Ding

    IPC: G01N33/487 ,  A61B5/145 ,  G01N33/53 ,  G01N33/66 ,  G01N33/49 ,  G01N33/58 ,  G01N35/08 ,  G01N1/22

    Abstract: Disclosed is a method for correlating a biomarker in a non-blood bodily fluid with the same biomarker in the blood of an individual, including: measuring, in a first period in time, the biomarker in non-blood bodily fluid and measuring the same biomarker in the blood of the same individual to establish an R ratio of [NBBF1]/[BB1], where [NBBF1] is the biomarker concentration in non-blood bodily fluid in the first period in time, and [BB1] is the biomarker concentration in the blood in the first period in time; storing the ratio in a memory; measuring, in a second period in time, the biomarker in non-blood bodily fluid to determine [NBBF2], where [NBBF2] is the biomarker concentration in the non-blood bodily fluid in the second period in time; and correlating the measured [NBBF2] with the R ratio to generate a correlated [BB2] biomarker concentration in the blood of the individual in the second period in time. Also disclosed is a device, apparatus, and method for correlating the glucose concentration in a non-blood bodily fluid such as saliva with the glucose in the blood of an individual.

    Digital Assay
    19.
    发明申请
    Digital Assay 审中-公开

    公开(公告)号：US20200038859A1

    公开(公告)日：2020-02-06

    申请号：US16484620

    申请日：2018-02-08

    Applicant: Essenlix Corporation

    Inventor： Stephen Y. Chou ,  Wei Ding ,  Yufan Zhang

    IPC: B01L3/00 ,  C12Q1/686 ,  G01N33/53

    Abstract: Provided herein is a method and device for partitioning a fluidic sample. The device contains a plate containing microwells. The method comprises depositing a sample on one or both of the plates when the plates are in an open configuration, wherein the deposition is in the form of a single or multiple droplet of the sample, wherein at least one of the droplets has a volume that occupies more than two microwells and closing the plates to the closed configuration to partition the sample in the microwells.

Patent Agency Ranking