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公开(公告)号:US12276660B2
公开(公告)日:2025-04-15
申请号:US17975537
申请日:2022-10-27
Applicant: Essenlix Corporation
Inventor: Stephen Y. Chou , Wei Ding
IPC: G01N1/00 , B01L3/00 , G01N1/28 , G01N1/30 , G01N33/50 , G01N33/543 , G16B25/00 , G16B50/00 , G16H80/00
Abstract: The present invention is related to the field of bio/chemical sampling, sensing, assays and applications. Particularly, the present invention is related to how to make the sampling/sensing/assay become simple to use, fast to results, highly sensitive, easy to use, using tiny sample volume (e.g., 0.5 μL or less), operated by a person without any professionals, reading by mobile-phone, or low cost, or a combination of them.
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公开(公告)号:US12276584B2
公开(公告)日:2025-04-15
申请号:US18142008
申请日:2023-05-01
Applicant: Essenlix Corporation
Inventor: Stephen Y. Chou , Wei Ding , Ji Qi
Abstract: Disclosed are devices and methods for analyzing an analyte, such as white blood cells in liquid samples.
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公开(公告)号:US12265019B2
公开(公告)日:2025-04-01
申请号:US17268677
申请日:2019-08-16
Applicant: Essenlix Corporation
Inventor: Stephen Y. Chou , Wei Ding , Ji Qi , Jun Tian
Abstract: Disclosed is an optical system for interrogating a sample, an optical system for measuring the spectrum of a beam of light, an optical system for measuring the spectrum of two beams of light, a compact imaging-based sensor or sensors, and combinations thereof.
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公开(公告)号:US12064771B2
公开(公告)日:2024-08-20
申请号:US16616680
申请日:2018-05-23
Applicant: Essenlix Corporation
Inventor: Stephen Y. Chou , Wei Ding , Hua Tan
CPC classification number: B01L7/52 , B01L3/5088 , B01L2300/1811 , B01L2300/1822 , B01L2300/1827
Abstract: The disclosure provides a device and method for rapidly changing temperatures of a sample. An example of the device include: a first plate; a second plate; and a heating/cooling layer disposed on either the first or second plate. The first plate and the second plate face each other and are configured to receive a fluid sample sandwiched therebetween. The method includes depositing the fluid sample on one or both of the two plates, pressing the plates to form a thin layer of the sample, and changing and/or maintaining the temperature of the sample. The device or method can be used in, for example, PCR.
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公开(公告)号:US20240192137A1
公开(公告)日:2024-06-13
申请号:US18584021
申请日:2024-02-22
Applicant: Essenlix Corporation
Inventor: Ji Qi , Stephen Y. Chou , Wei Ding
IPC: G01N21/64
CPC classification number: G01N21/6428 , G01N21/6458 , G01N2021/6439 , G01N2201/021 , G01N2201/0634 , G01N2201/0636
Abstract: A multi-mode illumination system, including: a first illumination module; a second illumination module; and a third illumination module, as disclosed herein.
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公开(公告)号:US11933720B2
公开(公告)日:2024-03-19
申请号:US17621216
申请日:2020-06-22
Applicant: Essenlix Corporation
Inventor: Stephen Y. Chou , Wei Ding , Ji Qi , Jun Tian , Wu Chou , Hongbing Li
CPC classification number: G01N21/31 , G01N21/03 , G01N2021/0346 , G01N2021/3129
Abstract: The disclosure provides an apparatus, a device, and methods for improving optical analysis of a thin layer of a sample between two plates, particularly for multiple wavelengths.
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公开(公告)号:US11927560B2
公开(公告)日:2024-03-12
申请号:US16484256
申请日:2018-02-08
Applicant: Essenlix Corporation
Inventor: Stephen Y. Chou , Wei Ding , Yufan Zhang
IPC: G01N27/403 , B01L3/00 , G01N1/28 , G01N1/38 , G01N21/84 , G01N33/49 , G01N33/543 , G01N35/00
CPC classification number: G01N27/403 , B01L3/502761 , G01N1/2813 , G01N1/286 , G01N1/38 , G01N21/8483 , G01N33/4905 , G01N33/5438 , G01N35/00 , B01L2200/0668 , B01L2300/0645 , B01L2300/0816 , B01L2300/0887 , B01L2400/0415
Abstract: Described are methods and devices that can accelerate the process and quantify the parameters for bio/chemical material samples. In some embodiments, a QMAX (Q: quantification; M: magnifying; A: adding reagents; X: acceleration) device having two or more electrodes capable of accelerating the electrical measurement process of the samples. In addition, the electrical measurement technology of the QMAX device enables for extraction, separation, and purification of sample components, such as but not limited to nucleic acids. In some embodiments, the QMAX device includes a plate for hosting a small sensing chip to facilitate a bio/chemical sensing of the sensing chip.
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公开(公告)号:US11796538B2
公开(公告)日:2023-10-24
申请号:US17300945
申请日:2021-12-15
Applicant: Essenlix Corporation
Inventor: Stephen Y. Chou , Wei Ding , Ji Li , Yufan Zhang
IPC: G01N1/00 , G01N33/543 , G01N1/28 , G01N1/02
CPC classification number: G01N33/54386 , G01N1/2813 , G01N2001/028
Abstract: The present invention provides devices, systems, and methods, for performing biological and chemical assays.
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公开(公告)号:US11733151B2
公开(公告)日:2023-08-22
申请号:US17284083
申请日:2020-04-06
Applicant: Essenlix Corporation
Inventor: Stephen Y. Chou , Wu Chou , Xing Li , Hongbing Li , Yuecheng Zhang , Mingquan Wu , Wei Ding , Jun Tian
CPC classification number: G01N15/1475 , G06N20/00 , G06T7/0012 , G06T7/10 , G06T7/40 , G06T7/62 , G06T2207/10056 , G06T2207/30004 , G06T2207/30024 , G06T2207/30204
Abstract: The present invention is related to, among other things, the devices and methods that improve the accuracy and reliability of an assay, even when the assay device and/or the operation of the assay device has certain errors, and in some embodiments the errors are random.
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公开(公告)号:US11648551B2
公开(公告)日:2023-05-16
申请号:US16772396
申请日:2018-12-12
Applicant: Essenlix Corporation
Inventor: Stephen Y. Chou , Wei Ding , Ji Qi , Hua Tan , Yufan Zhang
CPC classification number: B01L3/502715 , B01L7/52 , C12Q1/686 , B01L2200/021 , B01L2200/10 , B01L2300/0816 , B01L2300/123 , B01L2300/1805
Abstract: Among other things, the present invention is related to devices and methods of performing biological and chemical assays, particularly an easy sample manipulation and/or a rapid change or a rapid thermal cycling of a sample temperature is needed (e.g. Polymerase Chain Reaction (PCR) for amplifying nucleic acids).
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