公开(公告)号：US20230228748A1

公开(公告)日：2023-07-20

申请号：US18181691

申请日：2023-03-10

Applicant: FUJIFILM Corporation

Inventor： Hiroyasu ISHII ,  Junya YOSHIDA ,  Yoshihiro ABURAYA

IPC: G01N33/569 ,  G01N1/40

CPC classification number: G01N33/5695 ,  G01N1/405 ,  G01N2469/10

Abstract: There are provided a sample solution concentration method that makes it possible to obtain a sample solution concentrated solution having a desired concentration fold ratio and a sample solution examination method using the sample solution concentration method. The sample solution concentration method includes, in the following order, a sample solution injection step of injecting a sample solution, which is an aqueous solution containing a high-molecular-weight molecule, into a cylinder accommodating a particulate super absorbent polymer, a water absorption step in which water contained in the sample solution injected into the cylinder is absorbed by the super absorbent polymer accommodated in the cylinder to generate a sample solution concentrate which is a concentrate of the sample solution, in the cylinder, a liquid addition step of adding a liquid having an amount smaller than an amount of the sample solution injected into the cylinder in the sample solution injection step, to the sample solution concentrate, and a taking-out step of inserting, into the cylinder, a piston insertable into the cylinder, the piston including a tip part having holes smaller than a particle diameter of the super absorbent polymer after water absorption, to take out a sample solution concentrated solution, which is a concentrated solution of the sample solution, through the holes in the tip part of the piston.

公开(公告)号：US20220341926A1

公开(公告)日：2022-10-27

申请号：US17859292

申请日：2022-07-07

Applicant: FUJIFILM Corporation

Inventor： Yoshihiro ABURAYA ,  Junichi KATADA

IPC: G01N33/543

Abstract: An immunological test method includes a concentration step of mixing a solution capable of containing an antigen, a superabsorbent polymer, and a labeled antibody against the antigen, to obtain a concentrated and mixed solution which is a concentrated mixed solution containing composite bodies of the antigen and the labeled antibody and a detection step of detecting the composite bodies in the concentrated and mixed solution using an antigen-antibody reaction, in which a swelling ratio of the superabsorbent polymer is more than 0.2 g/g and less than 800 g/g.

公开(公告)号：US20200221652A1

公开(公告)日：2020-07-16

申请号：US16826284

申请日：2020-03-22

Applicant: FUJIFILM Corporation

Inventor： Yuichi WAKATA ,  Saori MATSUYAMA ,  Takafumi HOSOKAWA ,  Yoshihiro ABURAYA

IPC: A01G22/25 ,  A01G7/06 ,  A01G31/00

Abstract: An object of the present invention is to provide a method for producing a plant in order to obtain a plant having a high content of a caffeoylquinic acid compound. Another object of the present invention is to provide a method for producing a processed plant product. The method for producing a plant according to the present invention includes a step of growing at least one plant selected from the group consisting of a tuber other than a sweet potato, a plant belonging to the family Convolvulaceae, and a plant belonging to the family Asteraceae; and a step of subjecting the grown plant to nutriculture using a culture solution which is substantially free of a nitrate ion and a phosphate ion.

公开(公告)号：US20230228749A1

公开(公告)日：2023-07-20

申请号：US18181761

申请日：2023-03-10

Applicant: FUJIFILM Corporation

Inventor： Hiroyasu ISHII ,  Junya YOSHIDA ,  Yoshihiro ABURAYA

IPC: G01N33/569 ,  G01N1/40 ,  G01N33/92 ,  G01N33/543

CPC classification number: G01N33/5695 ,  G01N1/405 ,  G01N33/92 ,  G01N33/54388

Abstract: There are provided a concentration device for concentrating a sample solution, which makes it possible to obtain a sample solution concentrated solution having a desired concentration fold ratio, a sample solution concentration method using the concentration device, a sample solution concentration method using the sample solution examination method, and an examination kit including the concentration device. The concentration device is a concentration device for concentrating a sample solution which is an aqueous solution containing a high-molecular-weight molecule, the concentration device including a cylinder that accommodates a particulate super absorbent polymer and a piston that is insertable into the cylinder, where the cylinder has, at a bottom part, a liquid holding part for holding a part of the sample solution injected into the cylinder, the super absorbent polymer is accommodated in the cylinder to be in contact with the liquid holding part on the liquid holding part, and the piston includes the tip part having holes smaller than the particle diameter of the super absorbent polymer after water absorption.

公开(公告)号：US20220326227A1

公开(公告)日：2022-10-13

申请号：US17851215

申请日：2022-06-28

Applicant: FUJIFILM Corporation

Inventor： Yoshihiro ABURAYA ,  Junichi KATADA

IPC: G01N33/531 ,  G01N33/543

Abstract: An immunochromatography includes a concentration step of concentrating a solution capable of containing an antigen by ultrafiltration to obtain an antigen-concentrated solution; a spreading step of spreading particle composite bodies on an insoluble carrier having a reaction site at which a second binding substance capable of binding to an antigen in the antigen-concentrated solution has been immobilized, in a state where the particle composite bodies which are composite bodies of the antigen and a modified particle which is a particle modified with a first binding substance capable of binding to the antigen are formed; a capturing step of capturing the particle composite bodies at the reaction site of the insoluble carrier; and an amplification step of amplifying information of the particle composite bodies captured in the capturing step.

公开(公告)号：US20220196647A1

公开(公告)日：2022-06-23

申请号：US17690177

申请日：2022-03-09

Applicant: FUJIFILM Corporation

Inventor： Yoshihiro ABURAYA ,  Naoyuki NISHIKAWA ,  Junichi KATADA ,  Atsuhiko WADA ,  Dai UJIHARA

IPC: G01N33/543 ,  G01N1/40

Abstract: An immunochromatography including steps of mixing an antigen-containable specimen and modified magnetic particles, which are magnetic particles modified with a monoclonal antibody X; collecting the magnetic particles from the mixture using magnetism; dissociating the modified magnetic particles to obtain an antigen-containing solution; neutralizing the antigen-containing solution to obtaina neutralized antigen-containing solution; spreading gold particle composite bodies on an insoluble carrier having a reaction site at which a monoclonal antibody Z has been immobilized, wherein the gold particle composite body is a composite body of the antigen and a modified gold particle which is a gold particle modified with a monoclonal antibody Y; capturing the gold particle composite bodies at the reaction site; and silver-amplifying the gold particle composite body, in which the antibody X and the antibody Y are different from each other, and the antibody X and the antibody Z are different from each other.

公开(公告)号：US20220011303A1

公开(公告)日：2022-01-13

申请号：US17487534

申请日：2021-09-28

Applicant: FUJIFILM Corporation

Inventor： Yoshihiro ABURAYA ,  Naoyuki NISHIKAWA ,  Junichi KATADA ,  Dai UJIHARA ,  Atsuhiko WADA

IPC: G01N33/543

Abstract: An object of the present invention is to provide immunochromatography exhibiting excellent magnetic detection sensitivity. The immunochromatography of the present invention is immunochromatography including a mixing step of mixing a specimen that is capable of containing a test substance with a modified composite particle that is a composite particle modified with a first binding substance that is capable of binding to the test substance, to obtain a complex of the test substance in the specimen and the modified composite particle; a developing step of developing the complex on an insoluble carrier having a reaction site at which a second binding substance capable of binding to the test substance is immobilized; a capturing step of capturing the complex at the reaction site of the insoluble carrier; and a silver amplification step of silver-amplifying the complex captured in the capturing step, where the composite particle is a composite particle of a magnetic particle and a gold particle carried on a surface of the magnetic particle.

公开(公告)号：US20210208138A1

公开(公告)日：2021-07-08

申请号：US17205649

申请日：2021-03-18

Applicant: FUJIFILM Corporation

Inventor： Yoshihiro ABURAYA ,  Naoyuki NISHIKAWA ,  Junichi KATADA ,  Hiroyuki CHIKU ,  Ayumi ERA

IPC: G01N33/543 ,  C01G49/08 ,  G01N33/531 ,  G01N33/553

Abstract: An object of the present invention is to provide a composite particle for an immunochromatography which has excellent spreadability, a method for manufacturing the same, and an immunochromatography using the composite particle for an immunochromatography. A composite particle for an immunochromatography of the present invention is a composite particle for an immunochromatography in which magnetic particles having an average particle size of 500 nm or less and gold particles having an average particle size of 500 nm or less are bound via an organic substance.

公开(公告)号：US20160243507A1

公开(公告)日：2016-08-25

申请号：US15145889

申请日：2016-05-04

Applicant: FUJIFILM Corporation

Inventor： Daisuke HIRAKI ,  Yoshihiro ABURAYA ,  Makoto SAWADA ,  Satoshi YONEYAMA

IPC: B01D71/70

CPC classification number: B01D71/70 ,  B01D53/228 ,  B01D67/0088 ,  B01D69/12 ,  B01D2323/02 ,  B01D2323/42 ,  B05D3/0413 ,  B05D3/067 ,  B05D2201/02 ,  B05D2201/04 ,  B05D2252/02 ,  B05D2518/10

Abstract: There is provided a method of producing a composite which is capable of suitably forming a silicone resin layer for preventing the facilitated transport film from entering the porous support in an acidic gas separation film formed by forming a facilitated transport film on a porous support, and the composite. The problem is solved by the method of producing a composite including hydrophilizing the surface of the porous support using a roll-to-roll system; and coating the hydrophilized surface of the porous support with a silicone coating solution that becomes the silicone resin layer using the roll-to-roll system.

Abstract translation: 提供一种复合体的制造方法，其能够适当地形成硅酮树脂层，以防止便利的输送膜在通过在多孔载体上形成便利的输送膜而形成的酸性气体分离膜中进入多孔载体，并且 综合。 该问题通过使用卷对卷系统使多孔载体的表面亲水化的复合体的制造方法来解决; 以及利用卷对卷系统成为有机硅树脂层的硅氧烷涂层溶液涂覆多孔载体的亲水化表面。

公开(公告)号：US20160136581A1

公开(公告)日：2016-05-19

申请号：US15006689

申请日：2016-01-26

Applicant: FUJIFILM Corporation

Inventor： Makoto SAWADA ,  Yoshihiro ABURAYA

IPC: B01D63/10 ,  B01D53/22

CPC classification number: B01D63/10 ,  B01D53/228 ,  B01D61/38 ,  B01D63/103 ,  B01D69/10 ,  B01D69/142 ,  B01D2053/221 ,  B01D2256/16 ,  B01D2256/245 ,  B01D2257/504 ,  B01D2313/105 ,  C10K1/024 ,  Y02C10/10 ,  Y02P20/152

Abstract: There is provided a high-quality spiral-type acidic gas separation module which is obtained by winding a laminate including an acidic gas separation layer that has a facilitated transport film and which has no defects in the facilitated transport film, in which the average value of the fiber diameter of a supply gas channel member is in a range of 100 μm to 900 μm, and the area ratio of concave portions inscribed in a hemisphere having a diameter greater than or equal to three-quarters of the fiber diameter of the supply gas channel member is 50% or less with respect to a surface of an auxiliary support film of a porous support that is on the side opposite to the facilitated transport film.

Abstract translation: 提供了一种高品质的螺旋型酸性气体分离组件，其通过卷绕包含具有便利的输送膜的酸性气体分离层并且在促进的输送膜中没有缺陷的层叠体获得，其中平均值 供给气体流路构件的纤维直径在100μm〜900μm的范围内，并且内径在直径大于等于供给气体的纤维直径的四分之三的半球的凹部的面积比 通道构件相对于与便利的输送膜相反的一侧的多孔载体的辅助支撑膜的表面为50％以下。