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公开(公告)号:US20250090537A1
公开(公告)日:2025-03-20
申请号:US18819051
申请日:2024-08-29
Applicant: Gilead Sciences, Inc.
Inventor: Byoung-Kwon Chun , Deeba Ensan , Dustin S. Siegel
IPC: A61K31/53 , A61K9/00 , A61P31/14 , C07D487/04
Abstract: Antiviral compounds and methods of using the same, singly or in combination with additional agents, and pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
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公开(公告)号:US20250057867A1
公开(公告)日:2025-02-20
申请号:US18589387
申请日:2024-02-27
Applicant: Gilead Sciences, Inc.
Inventor: Bruce S. Ross , Michael Joseph Sofia , Ganapati Reddy Pamulapati , Suguna Rachakonda , Hai-Ren Zhang , Byoung-Kwon Chun , Peiyuan Wang
Abstract: Disclosed herein are nucleoside phosphoramidates and their use as agents for treating viral diseases. These compounds are inhibitors of RNA-dependent RNA viral replication and are useful as inhibitors of HCV NS5B polymerase, as inhibitors of HCV replication and for treatment of hepatitis C infection in mammals.
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公开(公告)号:US20250034186A1
公开(公告)日:2025-01-30
申请号:US18755378
申请日:2024-06-26
Applicant: Gilead Sciences, Inc.
Inventor: Byoung-Kwon Chun , Edward Doerffler , Dustin S. Siegel , Andrew C. Stevens , Tiago Vieira
IPC: C07F9/6561 , A61P31/14 , A61P31/16 , C07D487/04
Abstract: The present disclosure provides a compound of Formula I: which is useful in treating a variety of diseases, such as diseases caused by respiratory syncytial virus (RSV), HRV, hMPV, ebola, Zika, West Nile, Dengue, HCV and/or HBV infection
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公开(公告)号:US20250034182A1
公开(公告)日:2025-01-30
申请号:US18750925
申请日:2024-06-21
Applicant: Gilead Sciences, Inc.
Inventor: Byoung-Kwon Chun , Michael O. Clarke , Deeba Ensan , Rao V. Kalla , Richard L. Mackman , Jagadeesh N. Manda , Devan Naduthambi , Dustin S. Siegel
Abstract: Phospholipid compounds and methods of using the same, singly or in combination with additional agents, and pharmaceutical formulations of said compounds for the treatment of viral infections are disclosed.
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公开(公告)号:US11939347B2
公开(公告)日:2024-03-26
申请号:US17355813
申请日:2021-06-23
Applicant: Gilead Sciences, Inc.
Inventor: Daniel H. Byun , Byoung-Kwon Chun , Michael O. Clarke , Petr Jansa , Rao V. Kalla , Dmitry Koltun , Richard L. Mackman , Thao D. Perry , Dustin S. Siegel , Scott P. Simonovich
IPC: A61K31/675 , A61K45/06 , A61P31/12 , C07F9/6561
CPC classification number: C07F9/6561 , A61K45/06
Abstract: Compounds and methods of using said compounds, singly or in combination with additional agents, and pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
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公开(公告)号:US11926645B2
公开(公告)日:2024-03-12
申请号:US17458023
申请日:2021-08-26
Applicant: Gilead Sciences, Inc.
Inventor: Elaine Bunyan , Byoung-Kwon Chun , Kassibla E. Dempah , Hon C. Hui , Rao V. Kalla , Richard L. Mackman
CPC classification number: C07H7/06 , A61P31/12 , C07B2200/13
Abstract: Compounds and methods of using said compounds, singly or in combination with additional agents, and salts, crystalline forms, pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
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公开(公告)号:US20210284670A1
公开(公告)日:2021-09-16
申请号:US17178463
申请日:2021-02-18
Applicant: Gilead Sciences, Inc.
Inventor: Gregory F. Chin , Byoung-Kwon Chun , Michael O. Clarke , Bindu Goyal , Hon C. Hui , Petr Jansa , Richard L. Mackman , Dustin S. Siegel , Hai Yang
IPC: C07F9/6561 , A61P31/14
Abstract: The present disclosure provides compounds for treating a variety of diseases, such as respiratory syncytial virus (RSV), HRV, hMPV, Ebola, Zika, West Nile, Dengue, and HCV.
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公开(公告)号:US12116380B2
公开(公告)日:2024-10-15
申请号:US17820183
申请日:2022-08-16
Applicant: Gilead Sciences, Inc.
Inventor: Byoung-Kwon Chun , Michael O. Clarke , Deeba Ensan , Rao V. Kalla , Richard L Mackman , Jagadeesh N. Manda , Devan Naduthambi , Dustin S. Siegel
IPC: C07F9/09 , A61K31/706 , A61P31/14
Abstract: Phospholipid compounds and methods of using the same, singly or in combination with additional agents, and pharmaceutical formulations of said compounds for the treatment of viral infections are disclosed.
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公开(公告)号:US20240287109A1
公开(公告)日:2024-08-29
申请号:US18544561
申请日:2023-12-19
Applicant: Gilead Sciences, Inc.
Inventor: Daniel H. Byun , Byoung-Kwon Chun , Michael O. Clarke , Petr Jansa , Rao V. Kalla , Dmitry Koltun , Richard L. Mackman , Thao D. Perry , Dustin S. Siegel , Scott P. Simonovich
IPC: C07F9/6561 , A61K45/06
CPC classification number: C07F9/6561 , A61K45/06
Abstract: Compounds and methods of using said compounds, singly or in combination with additional agents, and pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
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公开(公告)号:US20240174704A1
公开(公告)日:2024-05-30
申请号:US18354362
申请日:2023-07-18
Applicant: GILEAD SCIENCES, INC.
Inventor: Gregory F. Chin , Byoung-Kwon Chun , Michael O. Clarke , Bindu Goyal , Hon C. Hui , Petr Jansa , Richard L. Mackman , Dustin S. Siegel , Hai Yang
IPC: C07F9/6561 , A61P31/14
CPC classification number: C07F9/6561 , A61P31/14
Abstract: The present disclosure provides compounds for treating a variety of diseases, such as respiratory syncytial virus (RSV), HRV, hMPV, Ebola, Zika, West Nile, Dengue, and HCV.
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