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公开(公告)号：US20170290827A1
公开(公告)日：2017-10-12
申请号：US15488035
申请日：2017-04-14
Applicant: Gilead Sciences, Inc.
Inventor： Kyla Bjornson , Eda Canales , Jeromy J. Cottell , Kapil K. Karki , Ashley A. Katana , Darryl Kato , Tetsuya Kobayashi , John O. Link , Ruben Martinez , Barton W. Phillips , Hyung-Jung Pyun , Michael Sangi , Adam J. Schrier , Dustin Siegel , James G. Taylor , Chinh V. Tran , Teresa Alejandra Trejo Martin , Randall W. Vivian , Zheng-Yu Yang , Jeff Zablocki , Sheila M. Zipfel
IPC: A61K31/498 , C07D403/14 , C07D241/36 , A61K31/401 , A61K31/10
Abstract: Compounds of Formula I are disclosed As well as pharmaceutically acceptable salts thereof. Methods of using said compounds and pharmaceutical compositions containing said compounds are also disclosed.
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公开(公告)号：US20170042961A1
公开(公告)日：2017-02-16
申请号：US15244926
申请日：2016-08-23
Applicant: Gilead Sciences, Inc.
Inventor： William E. Delaney, IV , John O. Link , Hongmei Mo , David W. Oldach , Adrian S. Ray , William J. Watkins , Cheng Yong Yang , Weidong Zhong
IPC: A61K38/05 , A61K31/675 , A61K31/7068 , A61K31/381 , A61K31/4184 , A61K31/501 , A61K31/706
CPC classification number: A61K38/05 , A61K31/381 , A61K31/40 , A61K31/401 , A61K31/4025 , A61K31/407 , A61K31/4178 , A61K31/4184 , A61K31/4188 , A61K31/4353 , A61K31/4436 , A61K31/501 , A61K31/5377 , A61K31/662 , A61K31/675 , A61K31/7056 , A61K31/706 , A61K31/7068 , A61K38/212 , A61K45/06 , A61K2300/00
Abstract: This invention relates to combinations of therapeutic molecules useful for treating hepatitis C virus infection. The present invention relates to methods, uses, dosing regimens, and compositions.
Abstract translation: 本发明涉及可用于治疗丙型肝炎病毒感染的治疗分子的组合。 本发明涉及方法，用途，给药方案和组合物。
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公开(公告)号：US09452154B2
公开(公告)日：2016-09-27
申请号：US14513900
申请日：2014-10-14
Applicant: Gilead Sciences, Inc.
Inventor： William E. Delaney, IV , John O. Link , Hongmei Mo , David W. Oldach , Adrian S. Ray , William J. Watkins , Cheng Yong Yang , Weidong Zhong
IPC: A61K31/675 , A61K31/4184 , A61K31/381 , A61K31/40 , A61K31/401 , A61K31/4025 , A61K31/407 , A61K31/4178 , A61K31/4188 , A61K31/4353 , A61K31/4436 , A61K31/662 , A61K31/7056 , A61K45/06 , A61K31/501 , A61K31/5377 , A61K38/21 , A61K31/706
CPC classification number: A61K38/05 , A61K31/381 , A61K31/40 , A61K31/401 , A61K31/4025 , A61K31/407 , A61K31/4178 , A61K31/4184 , A61K31/4188 , A61K31/4353 , A61K31/4436 , A61K31/501 , A61K31/5377 , A61K31/662 , A61K31/675 , A61K31/7056 , A61K31/706 , A61K31/7068 , A61K38/212 , A61K45/06 , A61K2300/00
Abstract: This invention relates to combinations of therapeutic molecules useful for treating hepatitis C virus infection. The present invention relates to methods, uses, dosing regimens, and compositions.
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公开(公告)号：US20160083368A1
公开(公告)日：2016-03-24
申请号：US14836774
申请日：2015-08-26
Applicant: Gilead Sciences, Inc.
Inventor： Gediminas Brizgys , Eda Canales , Randall L. Halcomb , Yunfeng Eric Hu , Darryl Kato , John O. Link , Qi Liu , Rpland D. Saito , Winston C. Tse , Jennifer R. Zhang
IPC: C07D401/14 , A61K45/06 , A61K31/4439 , C07D471/04 , A61K31/444 , C07D493/04 , A61K31/4709 , C07D403/14 , C07D405/14 , C07D413/14 , A61K31/5377 , A61K31/496 , A61K31/506 , C07D519/00
CPC classification number: C07D401/14 , A61K31/4439 , A61K31/444 , A61K31/4709 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K45/06 , A61P31/18 , C07D403/14 , C07D405/14 , C07D413/14 , C07D471/04 , C07D493/04 , C07D498/04 , C07D519/00
Abstract: Compounds of formula I: or salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for treating a Retroviridae viral infection including an infection caused by the HIV virus.
Abstract translation: 公开了式I化合物或其盐。 还公开了包含式I化合物的药物组合物，制备式I化合物的方法，可用于制备式I化合物的中间体和用于治疗包括HIV病毒引起的感染的逆转录病毒科病毒感染的治疗方法。
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公开(公告)号：US09284323B2
公开(公告)日：2016-03-15
申请号：US14370466
申请日：2013-01-03
Applicant: Gilead Sciences, Inc.
Inventor： Kerim Babaoglu , Gediminas Brizgys , Hongyan Guo , Paul Hrvatin , Eric Lansdon , John O. Link , Hongtao Liu , Ryan McFadden , Michael L. Mitchell , Yingmei Qi , Paul A. Roethle , Randall W. Vivian , Lianhong Xu , Hong Yang
IPC: C07D491/06 , A61K45/06 , C07C59/64 , C07D213/55 , C07D231/56 , C07D491/04 , C07D277/34 , A61K31/192 , A61K31/426 , A61K31/436 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/506 , A61K31/5377 , C07D277/30
CPC classification number: C07D491/06 , A61K31/192 , A61K31/426 , A61K31/436 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/506 , A61K31/5377 , A61K45/06 , C07C59/64 , C07D213/55 , C07D231/56 , C07D277/30 , C07D277/34 , C07D491/04
Abstract: The invention provides compounds and salts thereof as d herein. The invention also provides pharmaceutical compositions comprising a compound disclosed herein, processes for preparing compounds disclosed herein, intermediates useful for preparing compounds disclosed herein and therapeutic methods for treating an HIV infection, treating the proliferation of the HIV virus, treating AIDS or delaying the onset of AIDS or ARC symptoms in a mammal using compounds disclosed herein.
Abstract translation: 本发明提供其化合物及其盐，如本文。 本发明还提供了包含本文公开的化合物的药物组合物，用于制备本文公开的化合物的方法，用于制备本文公开的化合物的中间体和治疗HIV感染的治疗方法，治疗HIV病毒的增殖，治疗AIDS或延迟 使用本文公开的化合物在哺乳动物中的AIDS或ARC症状。
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Patent Agency Ranking
公开(公告)号：US20150361087A1
公开(公告)日：2015-12-17
申请号：US14734264
申请日：2015-06-09
Applicant: Gilead Sciences, Inc.
Inventor： Elizabeth M. Bacon , Jeromy J. Cottell , John O. Link , Teresa Alejandra Trejo Martin , Sheila Zipfel
IPC: C07D493/06
CPC classification number: C07D493/06
Abstract: The disclosure is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
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17.发明申请2- (TERT - BUTOXY) -2- (7 -METHYLQUINOLIN- 6 - YL) ACETIC ACID DERIVATIVES FOR TREATING AIDS 有权2-（叔丁基氧基）-2-（7-甲基喹啉-6-基）乙酸衍生物，用于治疗艾滋病公开(公告)号：US20150045374A1
公开(公告)日：2015-02-12
申请号：US14370464
申请日：2013-01-03
Applicant: Gilead Sciences, Inc.
Inventor： Kerim Babaoglu , Kyla L. Bjornson , Paul Hrvatin , Eric Lansdon , John O. Link , Hongtao Liu , Ryan McFadden , Michael L. Mitchell , Yingmei Qi , Paul A. Roethle , Lianhong Xu
IPC: C07D215/227 , A61K31/4704 , A61K31/506 , C07D519/00 , A61K31/4745 , A61K45/06 , C07D491/06 , A61K31/4741 , A61K31/497
CPC classification number: C07D215/227 , A61K31/4704 , A61K31/4741 , A61K31/4745 , A61K31/497 , A61K31/506 , A61K45/06 , C07D491/06 , C07D519/00
Abstract: The invention provides compounds and salts thereof as d herein. The invention also provides pharmaceutical compositions comprising a compound disclosed herein, processes for preparing compounds disclosed herein, intermediates useful for preparing compounds disclosed herein and therapeutic methods for treating an HIV infection, treating the proliferation of the HIV virus, treating AIDS or delaying the onset of AIDS or ARC symptoms in a mammal using compounds disclosed herein.
Abstract translation: 本发明提供其化合物及其盐，如本文。 本发明还提供了包含本文公开的化合物的药物组合物，用于制备本文公开的化合物的方法，用于制备本文公开的化合物的中间体和治疗HIV感染的治疗方法，治疗HIV病毒的增殖，治疗AIDS或延迟 使用本文公开的化合物在哺乳动物中的AIDS或ARC症状。
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公开(公告)号：US08822430B2
公开(公告)日：2014-09-02
申请号：US13956195
申请日：2013-07-31
Applicant: Gilead Sciences, Inc.
Inventor： Elizabeth M. Bacon , Eda Canales , Aesop Cho , Jeromy J. Cottell , Manoj C. Desai , Michael Graupe , Hongyan Guo , Randall L. Halcomb , Darryl Kato , Choung U. Kim , Thorsten A. Kirschberg , Evan S. Krygowski , Scott E. Lazerwith , John O. Link , Hongtao Liu , Qi Liu , Richard L. Mackman , Michael L. Mitchell , Jay P. Parrish , Hyung-Jung Pyun , Joseph H. Saugier , Scott D. Schroeder , Jianyu Sun , James G. Taylor , James D. Trenkle , Winston C. Tse , Randall W. Vivian , William J. Watkins , Lianhong Xu
IPC: C07D401/14 , C07D403/04 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/04 , C07D417/04 , C07D417/14 , C07D495/04 , A61K31/4178 , A61K31/7068 , A61K31/7052 , A61K31/4184 , A61P1/16 , A61P31/14
CPC classification number: C07D403/14 , A61K31/4025 , A61K31/4178 , A61K31/4184 , A61K31/427 , A61K31/435 , A61K31/437 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/519 , A61K31/5377 , A61K31/5415 , A61K31/55 , A61K45/06 , A61P31/12 , C07D207/16 , C07D401/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D471/08 , C07D471/10 , C07D487/04 , C07D491/113 , C07D495/04 , C07F5/025
Abstract: The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
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公开(公告)号：US20140178336A1
公开(公告)日：2014-06-26
申请号：US13830346
申请日：2013-03-14
Applicant: Gilead Sciences, Inc.
Inventor： John O. Link , Jeromy J. Cottell , Teresa Alejandra Trejo Martin , Elizabeth M. Bacon
IPC: C07D491/052 , A61K31/7072 , A61K31/7068 , A61K38/21 , A61K31/4188 , A61K31/7056
CPC classification number: C07D491/052 , A61K31/352 , A61K31/4188 , A61K31/7056 , A61K31/7068 , A61K31/7072 , A61K38/21 , A61K45/06 , C07D491/04
Abstract: The disclosure is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
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公开(公告)号：US08575135B2
公开(公告)日：2013-11-05
申请号：US13783056
申请日：2013-03-01
Applicant: Gilead Sciences, Inc.
Inventor： Elizabeth M. Bacon , Jeromy J. Cottell , Ashley Anne Katana , Darryl Kato , Evan S. Krygowski , John O. Link , James Taylor , Chinh Viet Tran , Teresa Alejandra Trejo Martin , Zheng-Yu Yang , Sheila Zipfel
IPC: A01N43/16 , A01N33/18 , A01N33/24 , A61K31/35 , A61K31/04 , C07D207/46 , C07D295/00
CPC classification number: C07D491/052 , A61K31/4188 , A61K31/7056 , A61K31/7064 , A61K31/7072 , A61K38/06 , A61K38/07 , A61K38/21 , A61K45/06 , A61K47/60 , C07D405/12 , C07F5/025 , Y10S514/894 , A61K2300/00
Abstract: The disclosure is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
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