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26 条记录 (耗时 0.032 秒)

    Methods of treating psychiatric substance abuse, and other disorders using combinations containing omega-3 fatty acids
    12.
    发明申请
    Methods of treating psychiatric substance abuse, and other disorders using combinations containing omega-3 fatty acids 审中-公开
    使用含有ω-3脂肪酸的组合治疗精神药物滥用的方法和其他疾病

    公开(公告)号：US20050129710A1

    公开(公告)日：2005-06-16

    申请号：US10962096

    申请日：2004-10-08

    申请人： Perry Renshaw ,  William Carlezon ,  Bruce Cohen

    发明人： Perry Renshaw ,  William Carlezon ,  Bruce Cohen

    IPC分类号： A61K31/202 ,  A61K31/225 ,  A61K31/513 ,  A61K31/7072 ,  A61K36/55

    CPC分类号： A61K45/06 ,  A61K31/20 ,  A61K31/202 ,  A61K31/225 ,  A61K31/513 ,  A61K31/7068 ,  A61K31/7072 ,  A61K2300/00

    摘要： The invention provides methods for treating or preventing psychiatric disorders, substance abuse disorders, and other conditions, e.g., cardiovascular disease and cancer, involving administration of a therapeutically-effective amount of a cytosine-containing or cytidine-containing compound, creatine-containing compound, adenosine-containing, adenosine-elevating compound, omega-3 fatty acids, or combinations thereof to a mammal. The invention further provides methods of enhancing neurodevelopment and delaying premature pregnancy by administration of an effective amount of a cytosine-containing or cytidine-containing compound, creatine-containing compound, adenosine-containing, adenosine-elevating compound, omega-3 fatty acids, or combinations thereof to a mammal.

    摘要翻译： 本发明提供治疗或预防精神疾病，药物滥用障碍和其它病症（例如心血管疾病和癌症）的方法，涉及给予治疗有效量的含胞嘧啶或含胞苷化合物，含肌酸的化合物， 含腺苷，腺苷升高化合物，ω-3脂肪酸或其组合。 本发明还提供了通过施用有效量的含胞嘧啶或含胞苷的化合物，含肌酸的化合物，含腺苷，腺苷升高化合物，ω-3脂肪酸或增加神经发育来延缓早产的方法 它们与哺乳动物的组合。

    Hypothermic preservation of biological tissues and cells
    13.
    发明授权
    Hypothermic preservation of biological tissues and cells 失效
    生物组织和细胞的低温保存

    公开(公告)号：US08124329B2

    公开(公告)日：2012-02-28

    申请号：US12437291

    申请日：2009-05-07

    申请人： Sergey V. Sheleg ,  Hugh LeRoy Hixon, Jr. ,  Sergei A. Svarovsky ,  Bruce Cohen

    发明人： Sergey V. Sheleg ,  Hugh LeRoy Hixon, Jr. ,  Sergei A. Svarovsky ,  Bruce Cohen

    IPC分类号： A01N1/00

    CPC分类号： A01N1/0221

    摘要： A method for hypothermic preservation of biological tissue for later recovery to a viable state includes flushing the biological tissue with a gas mixture of sulfur hexafluoride or xenon and oxygen. The sulfur hexafluoride or xenon is in a concentration in the mixture between about 75 mole percent to 95 mole percent. The method includes pressurizing the biological tissue, preferably isothermically, with the mixture to a pressure that will form clathrates inside the biological tissue at a desired storage temperature in a range of about +1° C. to about +5° C. The method includes a step of cooling the biological tissue, preferably isobarically, to the desired storage temperature. Optional steps for further cooling to no colder than about −20° C. and for depressurization are provided as well as steps for recovering the hypothermically preserved biological tissue to a viable state, preferably using a recovery gas mixture.

    摘要翻译： 生物组织的低温保存方法以便稍后恢复到可行状态包括用六氟化硫或氙气和氧气的混合物冲洗生物组织。 六氟化硫或氙的混合浓度为约75摩尔％至95摩尔％。 该方法包括将生物组织，优选等温地加压至在约+ 1℃至约+ 5℃的范围内的所需储存温度下将在生物组织内形成包合物的压力。该方法包括 将生物组织，优选地等温地冷却至所需的储存温度的步骤。 提供进一步冷却至不低于约-20℃并用于减压的可选步骤，以及用于将低温保存的生物组织回收至可行状态的步骤，优选使用回收气体混合物。

    Method for making a microcannula
    14.
    发明授权
    Method for making a microcannula 失效
    制作微型插管的方法

    公开(公告)号：US06248196B1

    公开(公告)日：2001-06-19

    申请号：US08968079

    申请日：1997-11-12

    申请人： Harold D. Waitz ,  Hal Sternberg ,  Paul E. Segall ,  Bruce Cohen

    发明人： Harold D. Waitz ,  Hal Sternberg ,  Paul E. Segall ,  Bruce Cohen

    IPC分类号： B65H6908

    CPC分类号： A61M25/065 ,  A61B17/3417 ,  A61B2017/00526 ,  A61M25/0606 ,  A61M2025/0042 ,  Y10T29/4987 ,  Y10T29/49872

    摘要： A microcannula suitable for cannulation of very small blood vessels having a sharp pointed trochar tightly but removable placed in the lumen of the microcannula. The trochar is held in place by contact friction from an area of reduced inside diameter distal to the tip end, formed by welding the end distal of the microcannula to a tube having a slightly larger diameter. A process for making a microcannula is also provided.

    摘要翻译： 适用于插入非常小的血管的微型插管，其具有紧密但可移除的锋利尖锐的针刺，放置在微型管腔的内腔中。 通过将微型插管的远端的末端焊接到具有稍大的直径的管形成的，通过从远端到末端的内径减小的区域的接触摩擦而将夹层固定在适当的位置。 还提供了制造微型管道的方法。

    Microcannula
    19.
    发明授权
    Microcannula 失效
    微型菜籽

    公开(公告)号：US5688246A

    公开(公告)日：1997-11-18

    申请号：US547618

    申请日：1995-10-24

    申请人： Harold D. Waitz ,  Hal Sternberg ,  Paul E. Segall ,  Bruce Cohen

    发明人： Harold D. Waitz ,  Hal Sternberg ,  Paul E. Segall ,  Bruce Cohen

    IPC分类号： A61B17/00 ,  A61B17/34 ,  A61M25/06 ,  A61M5/178

    CPC分类号： A61M25/065 ,  A61B17/3417 ,  A61M25/0606 ,  A61B2017/00526 ,  A61M2025/0042 ,  Y10T29/4987 ,  Y10T29/49872

    摘要： A microcannula suitable for cannulation of very small blood vessels in a small animal, neonate or adult having a sharp pointed trochar tightly but removable placed in the lumen of the microcannula. The trochar is held in place by contact friction from an area of reduced inside diameter distal to the tip end, formed by welding the end distal of the microcannula to a tube having a slightly larger diameter. A process for making a microcannula.

    摘要翻译： 适合于在小动物，新生儿或成年人中插入非常小的血管的微型插管，其具有紧密但可移除的尖锐的针刺，放置在微型管腔的内腔中。 通过将微型插管的远端的末端焊接到具有稍大的直径的管形成的，通过从远端到末端的内径减小的区域的接触摩擦而将夹层固定在适当的位置。 制作微型菜单的过程。