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公开(公告)号：US20110178398A1
公开(公告)日：2011-07-21
申请号：US12946725
申请日：2010-11-15
IPC分类号： A61B6/00
CPC分类号： A61B5/6852 , A61B5/0062 , A61B5/0066 , A61B5/0084 , A61B5/02007
摘要： An apparatus, method and software arrangement for imaging a surface of a structure that is in contact with an opaque fluid is provided. The apparatus includes an article of manufacture (e.g., a housing), a fluid delivery arrangement and an imaging arrangement. The housing includes an aperture formed in the article of manufacture. The fluid delivery arrangement is configured to deliver a volume of substantially transparent fluid to the aperture formed in the housing. The imaging arrangement is configured to image the surface of the structure using an imaging modality after the volume of the transparent fluid is delivered to the aperture, wherein the imaging arrangement and/or the article of manufacture is translated along the surface of the structure while imaging the surface of the structure.
摘要翻译： 提供了一种用于对与不透明流体接触的结构的表面进行成像的装置，方法和软件装置。 该装置包括制品（例如，壳体），流体输送装置和成像装置。 壳体包括形成在制品中的孔。 流体输送装置构造成将一定体积的基本上透明的流体输送到形成在壳体中的孔。 成像装置被配置为在将透明流体的体积传送到孔之后使用成像模态来对结构的表面进行成像，其中成像装置和/或制品在结构的表面上被平移，而成像 结构的表面。
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公开(公告)号：US09254102B2
公开(公告)日：2016-02-09
申请号：US13226274
申请日：2011-09-06
CPC分类号： A61B5/6852 , A61B5/0062 , A61B5/0066 , A61B5/0084 , A61B5/02007
摘要： An apparatus, method and software arrangement for imaging a surface of a structure that is in contact with an opaque fluid is provided. The apparatus includes an article of manufacture (e.g., a housing), a fluid delivery arrangement and an imaging arrangement. The housing includes an aperture formed in the article of manufacture. The fluid delivery arrangement is configured to deliver a volume of substantially transparent fluid to the aperture formed in the housing. The imaging arrangement is configured to image the surface of the structure using an imaging modality after the volume of the transparent fluid is delivered to the aperture, wherein the imaging arrangement and/or the article of manufacture is translated along the surface of the structure while imaging the surface of the structure.
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13.发明授权Fiber-optic rotational device, optical system and method for imaging a sample 有权光纤旋转装置，光学系统和用于成像样品的方法公开(公告)号：US07382949B2
公开(公告)日：2008-06-03
申请号：US11266779
申请日：2005-11-02
CPC分类号： A61B1/3137 , A61B1/00183 , A61B1/042 , A61B5/0066 , A61B5/0084 , A61B5/6852 , A61B18/22 , A61B2017/00477 , G02B6/32 , G02B6/3604
摘要： A device, system and method for transmitting electro-magnetic radiation between at least two separate fibers (as well as for imaging a sample) are provided. For example, a first optical fiber and a second optical fiber may be provided, such that the first and/or second fibers is/are rotatable. At least one first optical arrangement may also be included which communicates with at least one end of the first optical fiber and/or the second optical fiber. Further, at least one second arrangement may be included which is configured to control a position of the optical arrangement to align longitudinal axes of the first and the second optical fibers at least at the ends thereof. In addition, at least one third arrangement can be provided which is adapted to rotate the first and/or second optical fibers at a rate that is greater than 40 revolutions per second. It is also possible to include at least one fourth arrangement which can be adapted for connecting the first optical fiber and/or the second optical fiber to a catheter arrangement, such that the fourth arrangement includes a protector provided at least at one end thereof, and wherein the protector is automatically removed upon a connection of the first and/or second optical fiber to the catheter arrangement via the fourth arrangement.
摘要翻译： 提供了用于在至少两个分离的光纤之间传送电磁辐射的装置，系统和方法（以及用于成像样品）。 例如，可以提供第一光纤和第二光纤，使得第一和/或第二光纤是可旋转的。 还可以包括与第一光纤和/或第二光纤的至少一端通信的至少一个第一光学布置。 此外，可以包括至少一个第二布置，其被配置成至少在其端部处控制光学装置的位置以对准第一和第二光纤的纵向轴线。 另外，可以提供至少一个第三布置，其适于以大于40转/秒的速率旋转第一和/或第二光纤。 还可以包括至少一个第四布置，其可以适于将第一光纤和/或第二光纤连接到导管装置，使得第四布置包括至少在其一端提供的保护器，以及 其中所述保护器在经由所述第四布置将所述第一和/或第二光纤连接到所述导管装置时自动移除。
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公开(公告)号：US08208995B2
公开(公告)日：2012-06-26
申请号：US11211483
申请日：2005-08-24
IPC分类号： A61B6/00
CPC分类号： A61B5/6852 , A61B5/0062 , A61B5/0066 , A61B5/0084 , A61B5/02007
摘要： An apparatus, method and software arrangement for imaging a surface of a structure that is in contact with an opaque fluid is provided. The apparatus includes an article of manufacture (e.g., a housing), a fluid delivery arrangement and an imaging arrangement. The housing includes an aperture formed in the article of manufacture. The fluid delivery arrangement is configured to deliver a volume of substantially transparent fluid to the aperture formed in the housing. The imaging arrangement is configured to image the surface of the structure using an imaging modality after the volume of the transparent fluid is delivered to the aperture, wherein the imaging arrangement and/or the article of manufacture is translated along the surface of the structure while imaging the surface of the structure.
摘要翻译： 提供了一种用于对与不透明流体接触的结构的表面进行成像的装置，方法和软件装置。 该装置包括制品（例如，壳体），流体输送装置和成像装置。 壳体包括形成在制品中的孔。 流体输送装置构造成将一定体积的基本上透明的流体输送到形成在壳体中的孔。 成像装置被配置为在将透明流体的体积传送到孔之后使用成像模态来对结构的表面进行成像，其中成像装置和/或制品在结构的表面上被平移，而成像 结构的表面。
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15.发明授权公开(公告)号：US10285568B2
公开(公告)日：2019-05-14
申请号：US13152784
申请日：2011-06-03
申请人： Guillermo J. Tearney , Brett Eugene Bouma , Michalina Gora , Melissa Suter , Hongki Yoo , Milen Shishkov
发明人： Guillermo J. Tearney , Brett Eugene Bouma , Michalina Gora , Melissa Suter , Hongki Yoo , Milen Shishkov
摘要： In accordance with exemplary embodiments of the present disclosure, device and method can be provided which can facilitate imaging of biological tissues, e.g., luminal organs in vivo, using optical techniques. The exemplary device can include different designs an features of one or more catheters, which can illuminate the tissues, and collect signals from the inside of the lumen. In another exemplary embodiment according to the present disclosure, a balloon-catheter can be provided with the flexible neck, which can absorb most of the bending. According to still another exemplary embodiments of the present disclosure, a balloon-catheter tethered capsule can be provided, and according a yet further exemplary embodiment, a structured balloon design can be provided with one or more protuberances, thus enabling imaging of the structures in close contact, e.g., without compressing of the tissue.
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16.发明授权Systems, devices, methods, apparatus and computer-accessible media for providing optical imaging of structures and compositions 有权用于提供结构和组合物的光学成像的系统，装置，方法，装置和计算机可访问介质公开(公告)号：US09557154B2
公开(公告)日：2017-01-31
申请号：US13114845
申请日：2011-05-24
申请人： Guillermo J. Tearney , Brett Eugene Bouma , Hongki Yoo , Milen Shishkov , Joseph Gardecki , Roman Shubochkin , Theodore Morse , Farouc Amin Jaffer
发明人： Guillermo J. Tearney , Brett Eugene Bouma , Hongki Yoo , Milen Shishkov , Joseph Gardecki , Roman Shubochkin , Theodore Morse , Farouc Amin Jaffer
CPC分类号： A61B5/0084 , A61B5/0066 , A61B5/0071 , A61B5/6852 , G01B9/02029 , G01B9/0205 , G01B9/02091 , G01N21/4795 , G01N21/64 , G01N21/6456 , G01N21/65 , G01N2201/0866
摘要： Exemplary systems, devices, methods, apparatus and computer-accessible media for providing and/or utilizing optical frequency domain imaging (OFDI) and fluorescence of structures and, e.g., multimodality imaging using OFDI techniques and fluorescence imaging techniques are described. For example, an arrangement can provide at least one electro-magnetic radiation to an anatomical structure. Such exemplary arrangement can include at least one optical core and at least one cladding at least partially surrounding the fiber(s). A region between the optical core(s) and the cladding(s) can have an index that is different from indexes of the optical core(s) and the cladding(s). The arrangement can also include at least one apparatus which is configured to transmit the radiation(s) via the optical core(s) and the cladding(s) to the anatomical structure.
摘要翻译： 描述了用于提供和/或利用光学频域成像（OFDI）和结构荧光以及例如使用OFDI技术和荧光成像技术的多模态成像的示例性系统，装置，方法，装置和计算机可访问介质。 例如，一种布置可以向解剖结构提供至少一个电磁辐射。 这种示例性布置可以包括至少一个光学芯和至少部分围绕光纤的至少一个包层。 光纤芯和包层之间的区域可以具有与光纤芯和包层的折射率不同的折射率。 该装置还可以包括至少一个被配置为经由光学核和包层传播辐射到解剖结构的装置。
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公开(公告)号：US08818149B2
公开(公告)日：2014-08-26
申请号：US13427463
申请日：2012-03-22
CPC分类号： G02B23/2453 , A61B1/00167 , A61B1/00188 , A61B1/002 , A61B5/0062 , A61B5/0066 , A61B5/0068 , A61B5/0084 , A61B5/0086 , B24B9/14 , G01J3/02 , G01J3/0205 , G01J3/0208 , G01J3/0218 , G01J3/0256 , G01J3/18 , G02B5/18 , G02B23/2469 , G02B23/26
摘要： Exemplary apparatus for obtaining information for a structure can be provided. For example, the exemplary apparatus can include at least one first optical fiber arrangement which is configured to transceive at least one first electro-magnetic radiation, and can include at least one fiber. The exemplary apparatus can also include at least one second focusing arrangement in optical communication with the optical fiber arrangement. The second arrangement can include a ball lens, and be configured to focus and provide there through the first electro-magnetic radiation to generate the focused electro-magnetic radiation. Further, the exemplary apparatus can include at least at least one dispersive third arrangement which can receive a particular radiation (e.g., the first electro-magnetic radiation(s) and/or the focused electro-magnetic radiation), and forward a dispersed radiation thereof to at least one section of the structure.
摘要翻译： 可以提供用于获得结构信息的示例性装置。 例如，示例性装置可以包括被配置为收发至少一个第一电磁辐射的至少一个第一光纤布置，并且可以包括至少一个光纤。 示例性装置还可以包括与光纤布置光学通信的至少一个第二聚焦装置。 第二布置可以包括球形透镜，并且被配置成通过第一电磁辐射聚焦并提供在其上，以产生聚焦的电磁辐射。 此外，示例性装置可以包括至少一个能够接收特定辐射（例如，第一电磁辐射和/或聚焦电磁辐射）的分散第三装置，并且将其分散的辐射 到结构的至少一个部分。
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18.发明申请Apparatus for Obtaining Information For A Structure Using Spectrally-Encoded Endoscopy Techniques and Methods for Producing One or More Optical Arrangements 有权用于使用光谱编码内窥镜技术获得信息的装置和用于产生一个或多个光学布置的方法公开(公告)号：US20120328241A1
公开(公告)日：2012-12-27
申请号：US13427463
申请日：2012-03-22
CPC分类号： G02B23/2453 , A61B1/00167 , A61B1/00188 , A61B1/002 , A61B5/0062 , A61B5/0066 , A61B5/0068 , A61B5/0084 , A61B5/0086 , B24B9/14 , G01J3/02 , G01J3/0205 , G01J3/0208 , G01J3/0218 , G01J3/0256 , G01J3/18 , G02B5/18 , G02B23/2469 , G02B23/26
摘要： Exemplary apparatus for obtaining information for a structure can be provided. For example, the exemplary apparatus can include at least one first optical fiber arrangement which is configured to transceive at least one first electro-magnetic radiation, and can include at least one fiber. The exemplary apparatus can also include at least one second focusing arrangement in optical communication with the optical fiber arrangement. The second arrangement can include a ball lens, and be configured to focus and provide there through the first electro-magnetic radiation to generate focused electro-magnetic radiation. Further, the exemplary apparatus can include at least at least one dispersive third arrangement which can receive a particular radiation (e.g., the first and/or focused electro-magnetic radiation(s), and forward a dispersed radiation thereof to at least one section of the structure. An end of the fiber(s) can be directly connected to the second focusing arrangement and/or the third arrangement(s).
摘要翻译： 可以提供用于获得结构信息的示例性装置。 例如，示例性装置可以包括被配置为收发至少一个第一电磁辐射的至少一个第一光纤布置，并且可以包括至少一个光纤。 示例性装置还可以包括与光纤布置光学通信的至少一个第二聚焦装置。 第二布置可以包括球透镜，并且被配置为通过第一电磁辐射聚焦并提供其中以产生聚焦的电磁辐射。 此外，示例性装置可以包括至少一个可接收特定辐射（例如，第一和/或聚焦的电磁辐射）并且将其分散的辐射转发到至少一个部分的分散第三布置 纤维的一端可以直接连接到第二聚焦装置和/或第三装置。
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19.发明授权Apparatus for obtaining information for a structure using spectrally-encoded endoscopy techniques and methods for producing one or more optical arrangements 有权用于使用光谱编码的内窥镜检查技术获得结构信息的装置和用于产生一个或多个光学装置的方法公开(公告)号：US08145018B2
公开(公告)日：2012-03-27
申请号：US11623852
申请日：2007-01-17
CPC分类号： G02B23/2453 , A61B1/00167 , A61B1/00188 , A61B1/002 , A61B5/0062 , A61B5/0066 , A61B5/0068 , A61B5/0084 , A61B5/0086 , B24B9/14 , G01J3/02 , G01J3/0205 , G01J3/0208 , G01J3/0218 , G01J3/0256 , G01J3/18 , G02B5/18 , G02B23/2469 , G02B23/26
摘要： Exemplary apparatus for obtaining information for a structure can be provided. For example, first optical fiber arrangement(s) can be provided which transceives at least one first electro-magnetic radiation, and can include at least one fiber. Second focusing arrangement(s) can be provided in optical communication with the optical fiber arrangement. The second arrangement can be configured to focus and provide there through the first electro-magnetic radiation. Third dispersive arrangement(s) can receive a particular radiation which is the first electro-magnetic radiation and/or the focused electro-magnetic radiation, and forward a dispersed radiation thereof to at least one section of the structure. At least one end of the fiber can be directly connected to the second focusing arrangement and/or the third dispersive arrangement.
摘要翻译： 可以提供用于获得结构信息的示例性装置。 例如，可以提供收发至少一个第一电磁辐射的第一光纤布置，并且可以包括至少一个光纤。 可以提供与光纤装置的光通信中的第二聚焦装置。 第二布置可以被配置成通过第一电磁辐射聚焦并提供到那里。 第三分散布置可以接收作为第一电磁辐射和/或聚焦电磁辐射的特定辐射，并将其分散的辐射转发到结构的至少一个部分。 光纤的至少一端可以直接连接到第二聚焦装置和/或第三色散装置。
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公开(公告)号：US20120035454A1
公开(公告)日：2012-02-09
申请号：US13226274
申请日：2011-09-06
IPC分类号： A61B6/00
CPC分类号： A61B5/6852 , A61B5/0062 , A61B5/0066 , A61B5/0084 , A61B5/02007
摘要： An apparatus, method and software arrangement for imaging a surface of a structure that is in contact with an opaque fluid is provided. The apparatus includes an article of manufacture (e.g., a housing), a fluid delivery arrangement and an imaging arrangement. The housing includes an aperture formed in the article of manufacture. The fluid delivery arrangement is configured to deliver a volume of substantially transparent fluid to the aperture formed in the housing. The imaging arrangement is configured to image the surface of the structure using an imaging modality after the volume of the transparent fluid is delivered to the aperture, wherein the imaging arrangement and/or the article of manufacture is translated along the surface of the structure while imaging the surface of the structure.
摘要翻译： 提供了一种用于对与不透明流体接触的结构的表面进行成像的装置，方法和软件装置。 该装置包括制品（例如，壳体），流体输送装置和成像装置。 壳体包括形成在制品中的孔。 流体输送装置构造成将一定体积的基本上透明的流体输送到形成在壳体中的孔。 成像装置被配置为在将透明流体的体积传送到孔之后使用成像模态来对结构的表面进行成像，其中成像装置和/或制品在结构的表面上被平移，而成像 结构的表面。
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