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公开(公告)号:US20240082839A1
公开(公告)日:2024-03-14
申请号:US18272792
申请日:2021-01-22
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Carson DENISON , Erik D. TORNIAINEN , Richard W. SEAVER , Pavel KORNILOVICH , Alexander GOVYADINOV , Anand Samuel JEBAKUMAR
IPC: B01L3/00
CPC classification number: B01L3/502746 , B01L2200/0642 , B01L2200/0684 , B01L2300/0848 , B01L2300/0874 , B01L2400/086
Abstract: A microfluidic device includes a chamber having sidewalls, a floor, a ceiling, and an inlet. The microfluidic device includes pillars extending from the floor to the ceiling of the chamber. Each pillar has an orientation relative to the inlet defined by a leading surface and a trailing corner opposite the leading corner. The trailing corner has an angle less than a threshold angle that is based on a fluidic contact angle. The orientations of the pillars relative to the inlet promote fluid flow from the inlet throughout the chamber without trapping gas at the sidewalls of the chamber.
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公开(公告)号:US20230001692A1
公开(公告)日:2023-01-05
申请号:US17782875
申请日:2020-02-14
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Viktor SHKOLNIKOV , Alexander GOVYADINOV
IPC: B41J2/14
Abstract: In example implementations, an apparatus is provided. The apparatus includes a channel, an opening in the channel, and a heating element aligned with the opening on opposite sides of the channel. The channel contains a droplet of a first liquid containing a particle, wherein the droplet is carried within a second liquid in the channel. The heating element is to heat the first liquid to generate a vapor in the first liquid to eject the droplet of the first liquid through the opening.
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公开(公告)号:US20220072535A1
公开(公告)日:2022-03-10
申请号:US17415839
申请日:2019-04-30
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Viktor SHKOLNIKOV , Alexander GOVYADINOV
IPC: B01L3/00
Abstract: The present disclosure relates to a microfluidic device including a microfluidic substrate and dry reagent-containing polymer particles. The microfluidic substrate includes a microfluidic-retaining region within the microfluidic substrate that is fluidly coupled to multiple microfluidic channels. The dry reagent-containing polymer particles include reagent and a degradable polymer. The reagent is releasable from the degradable polymer when exposed to release fluid. The dry reagent-containing particles are retained within the microfluidic substrate at the microfluidic-retaining region in position to release reagent into the egress microfluidic channel upon flow of release fluid from the ingress microfluidic channel through the microfluidic-retaining region.
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公开(公告)号:US20200290041A1
公开(公告)日:2020-09-17
申请号:US16768248
申请日:2018-08-30
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Alexander GOVYADINOV , Pavel KORNILOVICH
Abstract: An example device includes a microfluidic channel and a movable element retained in the microfluidic channel to move from a first position to a second position by fluid flow through the microfluidic channel. The device includes a sensor to take a sensor reading to determine fluid flow through the microfluidic channel. The device includes a microfluidic pump to return the movable element from the second position to the first position. The device includes a controller to actuate the microfluidic pump and to determine a flow rate of the fluid flow through the microfluidic channel based on the sensor reading.
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公开(公告)号:US20200030760A1
公开(公告)日:2020-01-30
申请号:US16300975
申请日:2016-07-06
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Alexander GOVYADINOV , Pavel KORNILOVICH , Erik D. TORNIAINEN , David P. MARKEL
Abstract: One example provides a microfluidic mixing device that includes a main fluidic channel to provide main fluidic channel flow and a number of I-shaped secondary channels extending outwardly from a portion of the main fluidic channel. A number of inertial pumps are located within the I-shaped secondary channels to create serpentine flows in the direction of the main fluidic channel flow or create vorticity-inducing counterflow in the main fluidic channel.
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公开(公告)号:US20190151846A1
公开(公告)日:2019-05-23
申请号:US16099246
申请日:2016-07-12
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Pavel KORNILOVICH , Alexander GOVYADINOV , David P. MARKEL , Erik D. TORNIAINEN
IPC: B01L3/00
Abstract: A microfluidic bead-packing method includes activating a first micropump to transfer active microbeads through an inlet microchannel from a bead suspension reservoir to an adsorbing channel; packing the microbeads in the adsorbing channel; and activating a second micropump to reverse flow through at least a portion of the inlet microchannel and to transfer a sample fluid through the inlet microchannel from a sample reservoir to the adsorbing channel such that the sample fluid interacts with the packed microbeads.
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公开(公告)号:US20240181449A1
公开(公告)日:2024-06-06
申请号:US18550286
申请日:2021-04-06
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Carson DENISON , Pavel KORNILOVICH , Richard W. SEAVER , Anand Samuel JEBAKUMAR , Erik D. TORNIANEN , Alexander GOVYADINOV
IPC: B01L3/00
CPC classification number: B01L3/502715 , B01L2300/0864 , B01L2300/161 , B01L2400/0406
Abstract: A microfluidic device includes a first channel, second channels, and a transition channel splitting the first channel into the second channels. The transition has a first end fluidically connected to the first channel and a second end fluidically connected to the second channels. The transition channel expands in width from a width of the first channel at the first end to no less than a sum of widths of the second channels at the second end so as to promote fluid flow from the first channel to the second channels.
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公开(公告)号:US20240165617A1
公开(公告)日:2024-05-23
申请号:US18550353
申请日:2021-04-06
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Erik D. TORNIANEN , Carson DENISON , Richard W. SEAVER , Anand Samuel JEBAKUMAR , Pavel KORNILOVICH , Alexander GOVYADINOV
IPC: B01L3/00
CPC classification number: B01L3/50273 , B01L2300/0877 , B01L2400/0406
Abstract: A microfluidic device includes a first channel having a first width and a second channel having a second width greater than the first width. The microfluidic device includes a transition channel having a first end fluidically connected to the first channel and a second end fluidically connected to the second channel. The transition channel expands in width from the first width to the second width so as to promote fluid flow from the first channel to the second channel.
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公开(公告)号:US20230415151A1
公开(公告)日:2023-12-28
申请号:US17848864
申请日:2022-06-24
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Peiyun Wang , Pavel KORNILOVICH , Alexander GOVYADINOV , Noorashekin Binte JAMIL , Sarita JAIRAM , Jinghua ZHAO
CPC classification number: B01L3/502715 , G01N11/00 , B01L2200/0647 , B01L2400/0406
Abstract: An example self-priming microfluidic structure can include a microfluidic channel including a floor and a ceiling. A channel height is defined as a distance between the floor and the ceiling. A channel height step can be in the floor, or ceiling, or both. The channel height downstream of the channel height step can be greater than the channel height upstream of the channel height step. An interior pillar can be positioned in the microfluidic channel extending from the floor to the ceiling. The interior pillar can include a widening portion at an upstream end of the interior pillar and a tapering portion at a downstream end of the interior pillar. The interior pillar can overlap the channel height step so that the interior pillar is partially upstream of the channel height step and partially downstream of the channel height step.
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公开(公告)号:US20230174908A1
公开(公告)日:2023-06-08
申请号:US17911553
申请日:2020-04-30
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Alexander GOVYADINOV , Viktor SHKOLNIKOV
Abstract: In example implementations, an apparatus is provided. The apparatus includes a channel, a reagent chamber, a synthetic jet channel, and an energy source. The channel is to hold a cell. The reagent chamber is coupled to the channel and stores a reagent. The synthetic jet channel is coupled to the channel and the reagent chamber. The energy source is located in the synthetic jet channel to heat a liquid in the synthetic jet channel to create a synthetic jet that carries the reagent through towards the cell to inject the reagent into the cell.
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