Fluid analyzer utilizing a laser beam
    11.
    发明授权
    Fluid analyzer utilizing a laser beam 失效
    使用激光束的流体分析仪

    公开(公告)号:US4365157A

    公开(公告)日:1982-12-21

    申请号:US271376

    申请日:1981-06-08

    IPC分类号: G01N21/71 B01D59/44

    CPC分类号: G01N21/718

    摘要: A method for studying a fluid by forming a stream of the fluid, exciting the stream by causing a laser beam to impinge thereon to produce secondary particles or quanta, and subjecting the resulting secondary particles or quanta to an analysis operation in an analyzer.

    摘要翻译: 一种用于通过形成流体流来研究流体的方法,通过使激光束在其上冲击以产生二次粒子或量子来激发流,以及使得到的二次粒子或量子在分析器中进行分析操作。

    Polycarbophosphazenes
    12.
    发明授权
    Polycarbophosphazenes 失效
    聚碳磷腈

    公开(公告)号:US5093438A

    公开(公告)日:1992-03-03

    申请号:US547708

    申请日:1990-07-03

    IPC分类号: C08G79/02

    CPC分类号: C08G79/025

    摘要: The synthesis of a new class of macromolecules, the polycarbophosphazenes, is reported. When heated at 120.degree. C., the cyclocarbophosphazene N.sub.3 P.sub.2 CCl.sub.5 undergoes ring-opening polymerization to afford the high polymeric polycarbophosphazene [N.sub.3 P.sub.2 CCl.sub.5 ].sub.n. The latter functions as a reactive macromolecular intermediate and undergoes halogen replacement with sodium phenoxide or aniline to afford the hydrolytically stable derivatives [N.sub.3 P.sub.2 C(OPh).sub.5 ].sub.n and [N.sub.3 P.sub.2 C(NHPh).sub.5 ].sub.n.

    摘要翻译: 据报道,新一类大分子的合成,即聚碳磷腈。 当加热到120℃时,环磷酰腈N 3 P 2 CCl 5进行开环聚合,得到高聚合物多碳代膦腈[N 3 P 2 CCl 5] n。 后者用作反应性大分子中间体,并用苯酚盐或苯胺进行卤素取代,得到水解稳定的衍生物[N 3 P 2 C(OPh)5] n和[N 3 P 2 C(NHPh)5] n。

    Method for producing selected mass spectra
    13.
    发明授权
    Method for producing selected mass spectra 失效
    生产选定质谱的方法

    公开(公告)号:US4209697A

    公开(公告)日:1980-06-24

    申请号:US872572

    申请日:1978-01-26

    IPC分类号: H01J49/16 B01D59/44 H01J39/40

    CPC分类号: H01J49/161

    摘要: In a method for producing selected mass spectra by directing electromagnetic radiation through an optical system onto sample material for vaporization, destruction, excitation and/ or ionization in the microrange, setting the expanse of the irradiation region of the sample by selection of the energy density of the radiation, and detecting the released particles, the radiation power density is varied for producing mass spectra having respectively different proportions of atom and molecule spectra.

    摘要翻译: 在通过将电磁辐射通过光学系统引导到样品材料上以在微区域中蒸发,破坏,激发和/或电离以产生选定质谱的方法中,通过选择样品的能量密度来设定样品的照射区域的宽度 辐射和检测释放的颗粒,辐射功率密度是不同的,用于产生具有不同比例的原子和分子光谱的质谱。

    PHARMACEUTICAL FORMULATION WITH ENHANCED SOLUBILITY FOR THE DELIVERY OF CORTICOSTEROIDS
    15.
    发明申请
    PHARMACEUTICAL FORMULATION WITH ENHANCED SOLUBILITY FOR THE DELIVERY OF CORTICOSTEROIDS 审中-公开
    具有增强溶解性的药用配方用于输送角质素

    公开(公告)号:US20080081070A1

    公开(公告)日:2008-04-03

    申请号:US11680276

    申请日:2007-02-28

    IPC分类号: A61K9/32 A61K31/56 A61P1/00

    摘要: Formulations have been developed to improve the solubility of corticosteroids such as fluticasone proprionate in a composition designed to achieve localized release of the drug in the small intestine and/or colon. In one embodiment, solid dispersions of fluticasone are prepared wherein the drug is blended with or coated onto a highly water soluble substrate such as nonpareil (sugar beads) then coated with a layer of polymer soluble in small intestinal fluid, then coated with an enteric coating. The inner polymer layer controls release of the drug, and the enteric coating, a pH sensitive polymer that is broken down in the ileum and colon, controls localized release of drug at various sites within the gastrointestinal tract. The multilayer pharmaceutical composition can be in the form of pellets, tablets compressed from pellets or pellets packed into capsules. The release profile of the drug can be manipulated by (1) altering size or shape (i.e., surface area) and solubility of the inert substrate; (2) the ratio of drug to polymer, the polymer composition and solubility, the porosity of the polymer; (3) the drug form (i.e., free base or salt, or which salt); and the thickness and/or surface area of the drug/polymer and/or enteric coating. In a preferred embodiment, the composition is administered orally. This may also be packaged to provide for an escalating or tapering dosage.

    摘要翻译: 已经开发了用于改善皮质类固醇(例如丙酸氟替卡松)在旨在实现药物在小肠和/或结肠中的局部释放的组合物中的溶解度的制剂。 在一个实施方案中,制备氟替卡松的固体分散体,其中将药物与高水溶性底物如非乳糖(糖珠)混合或涂覆在其上,然后用可溶于小肠液的聚合物层涂覆,然后用肠溶衣 。 内部聚合物层控制药物的释放,并且肠溶衣(在回肠和结肠中分解的pH敏感聚合物)控制药物在胃肠道内各处的局部释放。 该多层药物组合物可以是丸粒形式,从颗粒或丸剂包装的胶囊中压制的片剂。 可通过(1)改变惰性底物的尺寸或形状(即表面积)和溶解度来操纵药物的释放曲线; (2)药物与聚合物的比例,聚合物组成和溶解度,聚合物的孔隙率; (3)药物形式(即游离碱或盐,或其盐); 以及药物/聚合物和/或肠溶衣的厚度和/或表面积。 在优选的实施方案中,组合物经口施用。 这也可以被包装以提供逐渐升高或渐细的剂量。

    Contact piece made of tungsten provided with a corrosion-resistant layer made of a base metal
    16.
    发明申请
    Contact piece made of tungsten provided with a corrosion-resistant layer made of a base metal 失效
    由钨制成的接触件具有由贱金属制成的耐腐蚀层

    公开(公告)号:US20060278507A1

    公开(公告)日:2006-12-14

    申请号:US10554175

    申请日:2004-04-19

    IPC分类号: H01H1/02

    CPC分类号: H01H1/02 Y10T29/49105

    摘要: The subject matter of the invention is a contact piece comprising a tungsten overlay soldered onto a support, wherein at least portions of the solder layer and optionally of the support are covered by a layer of a less noble metal than tungsten. The corrosion resistance of the tungsten overlay is considerably improved by the invention.

    摘要翻译: 本发明的主题是包括焊接到支撑件上的钨覆层的接触片,其中焊料层和任选的支撑体的至少一部分被比钨低的贵重金属层覆盖。 通过本发明,钨覆层的耐腐蚀性大大提高。