公开(公告)号：US07855093B2

公开(公告)日：2010-12-21

申请号：US12572720

申请日：2009-10-02

申请人： Kaoru Okamoto ,  Ryu Washino ,  Kazuhiro Komatsu ,  Yasushi Sakuma

发明人： Kaoru Okamoto ,  Ryu Washino ,  Kazuhiro Komatsu ,  Yasushi Sakuma

IPC分类号： H01L21/30

CPC分类号： H01S5/12 ,  B82Y20/00 ,  H01S5/1231 ,  H01S5/125 ,  H01S5/34306 ,  H01S5/34313

摘要： A method of manufacturing semiconductor laser device capable of reducing κL, with manufacturing restrictions satisfied, is provided. In a distributed-feedback or distributed-reflective semiconductor laser device, immediately before burying regrowth of a diffraction grating, halogen-based gas is introduced to a reactor, and etching is performed on the diffraction grating so that each side wall has at least two or more crystal faces and a ratio of length of an upper side in a waveguide direction to a bottom side parallel to a (100) surface is 0 to 0.3. And, a reactive product formed on side surfaces of the diffraction grating and in trench portions between stripes of the diffraction grating at an increase of temperature for regrowth is removed. Therefore, the diffraction grating with reduced height and a sine wave shape is obtained, thereby κL of the device is reduced. Thus, an oscillation threshold and optical output efficiency can be improved.

摘要翻译： 提供了一种制造半导体激光器件的方法，该半导体激光器装置能够在制造限制满足的情况下降低L。 在分布反馈或分布反射半导体激光器件中，在埋入衍射光栅的再生长之前，将卤素基气体引入反应器，并在衍射光栅上进行蚀刻，使得每个侧壁具有至少两个或 更多的晶面和波导方向的上侧与平行于（100）面的底面的长度的比率为0〜0.3。 并且，在再生长温度升高时，衍射光栅的侧面和衍射光栅的条纹之间的沟槽部分中形成的反应产物被去除。 因此，获得具有降低的高度和正弦波形的衍射光栅，从而减小了器件的衰减。 因此，可以提高振荡阈值和光输出效率。

公开(公告)号：US20100157781A1

公开(公告)日：2010-06-24

申请号：US12719119

申请日：2010-03-08

申请人： Jun Sumioka ,  Masakuni Yamamoto ,  Kaoru Okamoto

发明人： Jun Sumioka ,  Masakuni Yamamoto ,  Kaoru Okamoto

IPC分类号： G11B7/00

CPC分类号： G11B20/1496 ,  G11B7/005 ,  G11B20/10222 ,  G11B2220/2537

摘要： An optical information reproducing method of reproducing multivalued information recorded on a track of an optical information medium having a recording/reproducing region, which has virtual cells arranged thereon at regular spacings, the multivalued information being recorded thereon by changing a length of an information pit in a track direction or an area of the information pit in a cell with the use of a light spot, and the multivalued information being reproduced by detecting the level of a multistage reproduced signal from the information pit. The method includes detecting a cell center value of the central cell among three continuous cells recorded with an M-value (M

摘要翻译： 一种光学信息再现方法，用于再现记录在具有记录/再现区域的光学信息介质的轨道上的多值信息，该信息介质具有以规则间隔布置在其上的虚拟单元，通过改变信息凹坑的长度来记录多值信息 使用光点的单元中的信息凹坑的轨道方向或区域，并且通过从信息坑检测多级再现信号的电平来再现多值信息。 该方法包括：以记录有N值（N≥3）的多个单元中的每个单元上的M值（M

公开(公告)号：US07738338B2

公开(公告)日：2010-06-15

申请号：US11765058

申请日：2007-06-19

申请人： Jun Sumioka ,  Masakuni Yamamoto ,  Kaoru Okamoto

发明人： Jun Sumioka ,  Masakuni Yamamoto ,  Kaoru Okamoto

IPC分类号： G11B5/09 ,  G11B7/00

CPC分类号： G11B20/1496 ,  G11B7/005 ,  G11B20/10222 ,  G11B2220/2537

摘要： An optical information reproducing method of reproducing multivalued information recorded on a track of an optical information medium having a recording/reproducing region, which has virtual cells arranged thereon at regular spacings. The multivalued information is recorded thereon by changing a length of an information pit in a track direction or an area of the information pit in a cell with the use of a light spot. The multivalued information is reproduced by detecting the level of a multistage reproduced signal from the information pit. The method includes sampling a reproduced signal in the multivalued information recorded in one cell with an M-value (M

摘要翻译： 一种光学信息再现方法，用于再现记录在具有记录/再现区域的光学信息介质的轨道上的多值信息，其具有以规则间隔布置在其上的虚拟单元。 通过使用光点改变单元格中的信息凹坑的轨道方向或信息凹坑的区域的长度来记录多值信息。 通过从信息坑检测多级再现信号的电平来再现多值信息。 该方法包括以M值（M

公开(公告)号：US20090002281A1

公开(公告)日：2009-01-01

申请号：US12145673

申请日：2008-06-25

申请人： Kaoru Okamoto ,  Tadahiko Hirai ,  Jun Sumioka

发明人： Kaoru Okamoto ,  Tadahiko Hirai ,  Jun Sumioka

IPC分类号： G09G3/30

CPC分类号： G09G3/3241 ,  G09G3/2014 ,  G09G2300/0842 ,  G09G2310/0251 ,  G09G2310/0262

摘要： An active matrix organic electroluminescence(EL) display comprises plural selection and data lines mutually crossed, and a pixel circuit connected to the selection and data lines and having switching devices, a storage capacitor and an organic EL device. In a part of a period that the pixel circuit connected to the selection line is being selected, an applied first data signal is held as a voltage at the storage capacitor of the selected pixel circuit. After the selection signal applying, a first current according to the held voltage is supplied to the organic EL device, and this emits light at luminance according to the first current. In another part of the period, a second current according to an applied second data signal is supplied to the organic EL device of the selected pixel circuit, and this emits light at luminance according to the second current.

摘要翻译： 有源矩阵有机电致发光（EL）显示器包括相互交叉的多个选择和数据线，以及连接到选择和数据线并具有开关器件，存储电容器和有机EL器件的像素电路。 在选择与选择线连接的像素电路的期间的一部分中，施加的第一数据信号作为所选像素电路的存储电容器的电压被保持。 在选择信号施加之后，根据保持电压的第一电流被提供给有机EL器件，并且根据第一电流发光。 在该周期的另一部分中，根据所施加的第二数据信号的第二电流被提供给所选择的像素电路的有机EL器件，并且根据第二电流发光。

公开(公告)号：US5912261A

公开(公告)日：1999-06-15

申请号：US575023

申请日：1995-12-19

申请人： Takayuki Kotani ,  Kaoru Okamoto ,  Yasuhiro Nagaki

发明人： Takayuki Kotani ,  Kaoru Okamoto ,  Yasuhiro Nagaki

IPC分类号： C07D233/66 ,  C07D233/72 ,  C07D233/74 ,  C07D233/96 ,  C07D239/22 ,  C07D417/06 ,  A61K31/415 ,  C07D239/02

CPC分类号： C07D233/66 ,  C07D233/72 ,  C07D233/96 ,  C07D239/22 ,  C07D417/06

摘要： Carboxyalkyl heterocyclic derivatives, pharmaceutically acceptable salts thereof, and therapeutic agents containing said compounds as an effective component are useful pharmaceuticals for the treatment of diabetic complications such as diabetic neuropathy, diabetic cataracts and retinopathy, diabetic nephropathy, diabetic dermopathy, and other diabetic microangiopathy. The compounds of the present invention are represented by the following general formula (A): ##STR1## The compounds of the present invention exhibit excellent inhibitory action towards aldose reductase with a high enzyme selectivity. Accordingly, they are useful as drugs for the therapy and prevention of various types of diabetic complications without substantially inhibiting aldehyde reductase.

摘要翻译： 含有所述化合物作为有效成分的羧甲基杂环衍生物，其药学上可接受的盐和治疗剂是用于治疗糖尿病性并发症如糖尿病性神经病，糖尿病性白内障和视网膜病变，糖尿病性肾病，糖尿病性皮肤病和其它糖尿病性微血管病变的有用药物。 本发明化合物由下列通式（A）表示：本发明化合物对酶选择性高的醛糖还原酶表现出优异的抑制作用。 因此，它们可用作治疗和预防各种类型的糖尿病并发症而不显着抑制醛还原酶的药物。

公开(公告)号：US5900426A

公开(公告)日：1999-05-04

申请号：US624746

申请日：1996-03-27

申请人： Hiroki Muramoto ,  Kiyoshi Fukuda ,  Taisuke Hasegawa ,  Kaoru Okamoto ,  Takayuki Kotani

发明人： Hiroki Muramoto ,  Kiyoshi Fukuda ,  Taisuke Hasegawa ,  Kaoru Okamoto ,  Takayuki Kotani

IPC分类号： C07D277/64 ,  A61K31/415

CPC分类号： C07D277/64

摘要： Benzothiazole derivatives, pharmaceutically acceptable salts thereof, and therapeutic agents containing said compounds as an effective component possess a lipid lowering activity and are useful pharmaceuticals for the treatment of hyperlipemia. The lipid lowering agents are of the formula: ##STR1## wherein R.sub.1 is halogen, trifluoromethyl, acetamido or --OX.sub.1 ; X.sub.1 is hydrogen, alkyl or acyl; R.sub.2 is hydrogen, halogen, alkyl, hydroxyalkyl, trifluoromethyl, nitro, amino which may be substituted with alkyl or acyl, carboxy which may be esterified with alkyl, or --OX.sub.2 ; X.sub.2 is hydrogen, alkyl, acyl, carboxyalkyl which may be esterified with alkyl; n is an integer from 1 to 3 denoting the number of substituents R.sub.2 ; and plural R.sub.2 may be the same or different when n is 2 or 3; with the proviso that R.sub.1 is a group other than halogen when R.sub.2 is hydrogen. The benzothiazole derivatives and their pharmaceutically acceptable salts significantly decrease cholesterol, triglyceride and low-density lipoprotein in blood.

摘要翻译： 苯并噻唑衍生物，其药学上可接受的盐和含有所述化合物作为有效成分的治疗剂具有降脂活性，并且是用于治疗高脂血症的有用药物。 降脂剂具有下式：其中R1是卤素，三氟甲基，乙酰氨基或-OX1; X1是氢，烷基或酰基; R 2是氢，卤素，烷基，羟基烷基，三氟甲基，硝基，可被烷基或酰基取代的氨基，可以被烷基或-OX 2酯化的羧基; X 2是可以被烷基酯化的氢，烷基，酰基，羧基烷基; n是1至3的整数，表示取代基R2的数目; 当n为2或3时，多个R2可以相同或不同; 条件是当R 2为氢时，R 1为卤素以外的基团。 苯并噻唑衍生物及其药学上可接受的盐显着降低血液中的胆固醇，甘油三酯和低密度脂蛋白。

公开(公告)号：US5681843A

公开(公告)日：1997-10-28

申请号：US575024

申请日：1995-12-19

申请人： Takayuki Kotani ,  Kaoru Okamoto ,  Yasuhiro Nagaki

发明人： Takayuki Kotani ,  Kaoru Okamoto ,  Yasuhiro Nagaki

IPC分类号： C07D233/90 ,  C07D233/96 ,  C07D401/06 ,  C07D403/06 ,  C07D409/06 ,  C07D417/06 ,  A10K31/415 ,  A01N43/50 ,  C07D233/02

CPC分类号： C07D401/06 ,  C07D233/96 ,  C07D403/06 ,  C07D409/06 ,  C07D417/06

摘要： Parabanic acid derivatives, pharmaceutically acceptable salts thereof, and therapeutic agents containing said compounds as an effective component are useful pharmaceuticals for the treatment of diabetic complications such as diabetic neuropathy, diabetic cataracts and retinopathy, diabetic nephropathy, diabetic dermopathy, and other diabetic microangiopathy. The compounds of the present invention are represented by the following general formula (I): ##STR1## wherein R is hydrogen, lower alkyl or benzyl; X is substituted phenyl, optionally substituted benzothiazolyl, optionally substituted naphthyl, optionally substituted pyridyl, anthraquinonyl, phthalimide, or thienyl; and n is an integer from 1 to 3. The compounds of the present invention exhibit excellent inhibitory action towards aldose reductase with a high enzyme selectivity. Accordingly, they are useful as drugs for the therapy and prevention of various types of diabetic complications without substantially inhibitory aldehyde reductase.

摘要翻译： 对映异酸衍生物，其药学上可接受的盐和含有所述化合物作为有效成分的治疗剂是用于治疗糖尿病性并发症如糖尿病性神经病变，糖尿病性白内障和视网膜病变，糖尿病性肾病，糖尿病性皮肤病和其它糖尿病性微血管病变的有用药物。 本发明的化合物由以下通式（I）表示：其中R是氢，低级烷基或苄基; X是取代的苯基，任选取代的苯并噻唑基，任选取代的萘基，任选取代的吡啶基，蒽醌基，邻苯二甲酰亚胺或噻吩基; n为1〜3的整数。本发明的化合物对具有高酶选择性的醛糖还原酶表现出优异的抑制作用。 因此，它们可用作治疗和预防各种类型的糖尿病并发症而不具有实质上抑制性醛还原酶的药物。

公开(公告)号：US08395613B2

公开(公告)日：2013-03-12

申请号：US12493784

申请日：2009-06-29

申请人： Kaoru Okamoto ,  Jun Sumioka ,  Tadahiko Hirai

发明人： Kaoru Okamoto ,  Jun Sumioka ,  Tadahiko Hirai

IPC分类号： G09G5/00

CPC分类号： G09G3/3233 ,  G09G2320/0285 ,  G09G2320/0295 ,  G09G2320/046

摘要： A display apparatus includes a plurality of pixels disposed in a matrix pattern, each of the pixels emitting light, an acquisition unit for acquiring degradation characteristics of an emission luminance of each pixel from a video signal or a signal output from the pixel, and a detection unit for detecting a boundary of pixels showing different degradation characteristics of the plurality of pixels based on the degradation characteristics acquired by the acquisition unit. A calculation unit calculates a correction amount of the video signal to the pixels in a periphery of the boundary such that the emission luminance is gently varied in the periphery of the boundary when the plurality of pixels in the periphery of the boundary detected by the detection unit are caused to emit light with a same video signal. In addition, a correction unit corrects the video signal based on the calculated correction amount, and a video image is displayed by the plurality of pixels based on the corrected video signal.

摘要翻译： 显示装置包括以矩阵状排列的多个像素，每个像素发光;获取单元，用于从视频信号或从像素输出的信号中获取每个像素的发光亮度的劣化特性，以及检测 用于基于由所述获取单元获取的劣化特性来检测显示所述多个像素的不同劣化特性的像素的边界的单元。 计算单元计算边界周边的像素的视频信号的校正量，使得当由检测单元检测到的边界的周边中的多个像素在发光亮度在边界的周围轻微变化时 导致以相同的视频信号发光。 此外，校正单元基于计算出的校正量来校正视频信号，并且基于校正的视频信号由多个像素显示视频图像。

公开(公告)号：US07808874B2

公开(公告)日：2010-10-05

申请号：US12719119

申请日：2010-03-08

申请人： Jun Sumioka ,  Masakuni Yamamoto ,  Kaoru Okamoto

发明人： Jun Sumioka ,  Masakuni Yamamoto ,  Kaoru Okamoto

IPC分类号： G11B5/09 ,  G11B7/00

CPC分类号： G11B20/1496 ,  G11B7/005 ,  G11B20/10222 ,  G11B2220/2537

摘要： An optical information reproducing method of reproducing multivalued information recorded on a track of an optical information medium having a recording/reproducing region, which has virtual cells arranged thereon at regular spacings, the multivalued information being recorded thereon by changing a length of an information pit in a track direction or an area of the information pit in a cell with the use of a light spot, and the multivalued information being reproduced by detecting the level of a multistage reproduced signal from the information pit. The method includes detecting a cell center value of the central cell among three continuous cells recorded with an M-value (M

摘要翻译： 一种光学信息再现方法，用于再现记录在具有记录/再现区域的光学信息介质的轨道上的多值信息，该信息介质具有以规则间隔布置在其上的虚拟单元，通过改变信息凹坑的长度来记录多值信息 使用光点的单元中的信息凹坑的轨道方向或区域，并且通过从信息坑检测多级再现信号的电平来再现多值信息。 该方法包括：以记录有N值（N≥3）的多个单元中的每个单元上的M值（M

公开(公告)号：US07808873B2

公开(公告)日：2010-10-05

申请号：US12719112

申请日：2010-03-08

申请人： Jun Sumioka ,  Masakuni Yamamoto ,  Kaoru Okamoto

发明人： Jun Sumioka ,  Masakuni Yamamoto ,  Kaoru Okamoto

IPC分类号： G11B5/09 ,  G11B7/00

CPC分类号： G11B20/1496 ,  G11B7/005 ,  G11B20/10222 ,  G11B2220/2537

摘要： An optical information reproducing method of reproducing multivalued information recorded on a track of an optical information medium having a recording/reproducing region, which has virtual cells arranged thereon at regular spacings, the multivalued information being recorded thereon by changing a length of an information pit in a track direction or an area of the information pit in a cell with the use of a light spot, and the multivalued information being reproduced by detecting the level of a multistage reproduced signal from the information pit. The method includes sampling reproduced signals in the multivalued information recorded in two continuous cells with an M-value (M

摘要翻译： 一种光学信息再现方法，用于再现记录在具有记录/再现区域的光学信息介质的轨道上的多值信息，该信息介质具有以规则间隔布置在其上的虚拟单元，通过改变信息凹坑的长度来记录多值信息 使用光点的单元中的信息凹坑的轨道方向或区域，并且通过从信息坑检测多级再现信号的电平来再现多值信息。 该方法包括以M值（M