摘要:
Methods useful in monitoring the functional status of a transplant in a patient by detecting the expression levels of gene panels are described herein. Algorithms for analysis of the expression for monitoring the functional status of transplants are also described.
摘要:
The invention presents methods of using splice variants and reagents thereof for diagnosing and monitoring the status of transplants and immune disorders including diagnosing, monitoring and predicting transplant rejection or non-rejection, steroid responsiveness, and onset or flare of immune disorders.
摘要:
A method for making a composite polyamide membrane comprising the steps of applying a polyfunctional amine monomer and polyfunctional acyl halide monomer to a surface of the porous support and interfacially polymerizing the monomers to form a thin film polyamide layer, wherein the method is includes at least one of the following steps: i) conducting the interfacial polymerization in the presence of a monomer comprising at least one phosphorous-containing functional group or salt thereof and an at least one amine-reactive functional group; and/or ii) applying such a monomer to the thin film polyamide layer.
摘要:
The disclosed technology comprises a device and a method for accurately determining the amount of electrical energy utilized in a circuit with a quarter-cycle transformer and transducers operating off quarter-cycle power. The method allows for a primary power meter associated with an entity which provides a power source to remain in operation, without modification, and for a second power meter to be utilized which accurately measures consumption of quarter-cycle power usage. An adjustment to an invoice can then be made, based on the difference.
摘要:
The present invention provides a nucleic acid sequence encoding a melanoma antigen recognized by T lymphocytes, designated MART-1. This invention further relates to bioassays using the nucleic acid sequence, protein or antibodies of this invention to diagnose, assess or prognoses a mammal afflicted with melanoma or metastata melanoma. This invention also provides immunogenic peptides derived from the MART-1 melanoma antigen-and a second melanoma antigen designated gp100. This invention further provides immunogenic peptides derived from the MART-1 melanoma antigen or gp100 antigen which have been modified to enhance their immunogenicity. The proteins and peptides provided can serve as an immunogen or vaccine to prevent or treat melanoma.
摘要:
The present invention discloses the identification, isolation and cloning of a gene encoding a novel cancer antigen NY ESO-1CAG-3 and peptides thereof derived from various open reading frames from the NY ESO-1 gene. The novel cancer antigen and peptides are recognized by cytotoxic T lymphocytes in an HLA restricted manner. The products of the gene are promising candidates for immunotherapeutic strategies for the prevention, treatment and diagnosis of patients with cancer.
摘要:
Apparatus and methods of printing on electrically writable media and electrically writable displays are described. In one aspect, a printer for printing on an electrically writable medium includes a source of an invisible charge species, and a charge species projector. The charge species projector is operable to project charge species from the source onto the medium to electrically reorient switchable display elements in the medium. In another aspect, a portable storage device that includes a memory and an electrically writable medium is received. Data is written to the memory of the portable data storage device. The electrically writable medium of the portable data storage device is printed on by electrically reorienting switchable display elements in the medium. In another aspect, an electrically writable display includes an electrically writable medium that is incorporated into a continuous web having an outward-facing side and an inward-facing side. The outward-facing side of the continuous web presents a display surface of the electrically writable medium. The electrically writable display further includes a scroll system that is operable to scroll the display surface of the electrically writable medium through a display area.
摘要:
Apparatus and methods of printing on electrically writable media and electrically writable displays are described. In one aspect, a printer for printing on an electrically writable medium includes a source of an invisible charge species, and a charge species projector. The charge species projector is operable to project charge species from the source onto the medium to electrically reorient switchable display elements in the medium. In another aspect, a portable storage device that includes a memory and an electrically writable medium is received. Data is written to the memory of the portable data storage device. The electrically writable medium of the portable data storage device is printed on by electrically reorienting switchable display elements in the medium. In another aspect, an electrically writable display includes an electrically writable medium that is incorporated into a continuous web having an outward-facing side and an inward-facing side. The outward-facing side of the continuous web presents a display surface of the electrically writable medium. The electrically writable display further includes a scroll system that is operable to scroll the display surface of the electrically writable medium through a display area.
摘要:
Unfucosylated huPAR polypeptides that contains huPA1-48 (SEQ ID NQ:22) are provided. These polypeptides are useful for treating diseases wherein antagonism of huPAR is therapeutically beneficial.
摘要翻译:提供了含有huPA1-48(SEQ ID NO:22)的非岩藻糖化huPAR多肽。 这些多肽可用于治疗huPAR拮抗作用是治疗有益的疾病。
摘要:
EGF muteins in which the histidine at position 16 is replaced with a neutral or acidic amino acid exhibit activity at pHs lower than obtainable with wild type EGF.