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61 条记录 (耗时 0.034 秒)

    ADMINISTRATION OF PYRIDINEDICARBOXYLIC ACID COMPOUNDS FOR STIMULATING OR INDUCING THE GROWTH OF HUMAN KERATINOUS FIBERS AND/OR ARRESTING THEIR LOSS
    12.
    发明申请
    ADMINISTRATION OF PYRIDINEDICARBOXYLIC ACID COMPOUNDS FOR STIMULATING OR INDUCING THE GROWTH OF HUMAN KERATINOUS FIBERS AND/OR ARRESTING THEIR LOSS 审中-公开
    吡啶二羧酸化合物的施用用于刺激或诱导人类激素纤维的生长和/或损害它们的损失

    公开(公告)号：US20100105741A1

    公开(公告)日：2010-04-29

    申请号：US12650777

    申请日：2009-12-31

    申请人： Maria Dalko ,  Geneviève Loussouarn ,  Charles El Rawadi ,  Christophe Boulle ,  Bruno Bernard

    发明人： Maria Dalko ,  Geneviève Loussouarn ,  Charles El Rawadi ,  Christophe Boulle ,  Bruno Bernard

    IPC分类号： A61K31/44

    CPC分类号： A61K8/4926 ,  A61K8/37 ,  A61K8/494 ,  A61K8/4953 ,  A61Q1/10 ,  A61Q7/00

    摘要： The invention relates to the use in a composition for caring for human hair or eyelashes of an effective amount of a pyridinedicarboxylic acid derivative of general formula (I) or of one of its salts, in which R1 and R2 represent, independently of one another, OH, OR′, —NH2, —NHR′ or —NR′R″, and R′ and R″ represent, independently of one another, a saturated or unsaturated and linear or branched C1-C18 alkyl radical or an aryl radical, this alkyl or aryl radical optionally being substituted by at least one OH, alkoxy, acyloxy, amino or alkylamino group, or R′ and R″ together represent a heterocycle, the composition being intended to induce and/or stimulate the growth of human keratinous fibers, such as the hair and eyelashes, and/or slow down their loss; the invention also relates to a cosmetic treatment intended to stimulate the growth of human keratinous fibers, such as the hair and eyelashes, and/or slow down their loss.

    摘要翻译： 本发明涉及用于照护人发或睫毛的组合物中有效量的通式（I）的吡啶二羧酸衍生物或其盐之一，其中R 1和R 2彼此独立地表示， OH，OR'，-NH 2，-NHR'或-NR'R“，R'和R”彼此独立地表示饱和或不饱和和直链或支链的C 1 -C 18烷基或芳基， 任选被至少一个OH，烷氧基，酰氧基，氨基或烷基氨基取代的烷基或芳基，或R'和R“一起表示杂环，该组合物旨在诱导和/或刺激人角质纤维的生长， 如头发和睫毛，和/或减慢他们的损失; 本发明还涉及旨在刺激人角质纤维如头发和睫毛的生长和/或减缓其损失的美容治疗。

    Indolecarboxylic compounds and their use as pharmaceutical compounds
    14.
    发明授权
    Indolecarboxylic compounds and their use as pharmaceutical compounds 失效
    吲哚羧化合物及其作为药物化合物的用途

    公开(公告)号：US06448285B1

    公开(公告)日：2002-09-10

    申请号：US09297636

    申请日：1999-07-26

    申请人： Bruno Bernard ,  Catherine Gerst ,  Jean-Baptiste Galey ,  Maria Dalko ,  Patrick Pichaud

    发明人： Bruno Bernard ,  Catherine Gerst ,  Jean-Baptiste Galey ,  Maria Dalko ,  Patrick Pichaud

    IPC分类号： A61K31405

    CPC分类号： A61Q19/00 ,  A61K8/492 ,  A61Q7/00 ,  C07D209/42 ,  C07D209/60

    摘要： The invention relates to the use, as active principle, in a physiologically acceptable medium, in a composition, of an effective amount of at least one compound of the indolecarboxylic family, this compound or these compositions being intended to treat disorders associated with overactivity of 5&agr;-reductase. These compounds or the compositions containing them are more particularly intended to treat androgen-dependent disorders such as seborrhoea and/or acne and/or hirsutism and/or androgenic alopecia. The invention also relates to novel compounds of the indolecarboxylic family and to compositions containing them.

    摘要翻译： 本发明涉及作为活性成分在生物学上可接受的介质中，在组合物中使用有效量的至少一种吲哚类羧酸化合物的化合物，该化合物或这些组合物旨在治疗与5α过度活性相关的疾病 - 还原酶。 这些化合物或含有它们的组合物更特别地用于治疗雄激素依赖性疾病如脂溢和/或痤疮和/或多毛症和/或雄激素性脱发。 本发明还涉及吲哚羧酸系的新化合物和含有它们的组合物。

    Compounds of the indolecarboxylic family and use thereof
    15.
    发明授权
    Compounds of the indolecarboxylic family and use thereof 失效
    吲哚羧酸家族的化合物及其用途

    公开(公告)号：US06596753B2

    公开(公告)日：2003-07-22

    申请号：US10176674

    申请日：2002-06-24

    申请人： Bruno Bernard ,  Catherine Gerst ,  Jean-Baptiste Galey ,  Maria Dalko ,  Patrick Pichaud

    发明人： Bruno Bernard ,  Catherine Gerst ,  Jean-Baptiste Galey ,  Maria Dalko ,  Patrick Pichaud

    IPC分类号： A61K31405

    CPC分类号： A61Q19/00 ,  A61K8/492 ,  A61Q7/00 ,  C07D209/42 ,  C07D209/60

    摘要： The invention relates to the use, as active principle, in a physiologically acceptable medium, in a composition, of an effective amount of at least one compound of the indolecarboxylic family, this compound or these compositions being intended to treat disorders associated with overactivity of 5&agr;-reductase. These compounds or the compositions containing them are more particularly intended to treat androgen-dependent disorders such as, for example, seborrhoea and/or acne and/or hirsutism and/or androgenic alopecia. The invention also relates to novel compounds of the indolecarboxylic family and to compositions-containing them.

    摘要翻译： 本发明涉及作为活性成分在生物学上可接受的介质中，在组合物中使用有效量的至少一种吲哚类羧酸化合物的化合物，该化合物或这些组合物旨在治疗与5α过度活性相关的疾病 - 还原酶。 这些化合物或含有它们的组合物更特别地旨在治疗雄激素依赖性疾病，例如，脂溢和/或痤疮和/或多毛症和/或雄激素性脱发。 本发明还涉及吲哚羧酸家族的新化合物和含有它们的组合物。