公开(公告)号：US20130095529A1

公开(公告)日：2013-04-18

申请号：US13635801

申请日：2011-03-17

申请人： Jin Man Cho ,  Jin Nam Lee ,  Hye Won Kim ,  Ji Hye Lee ,  Nan Young Yoon ,  Kwang Woo Lee ,  Yoon Seok Oh ,  Jang Hee Park

发明人： Jin Man Cho ,  Jin Nam Lee ,  Hye Won Kim ,  Ji Hye Lee ,  Nan Young Yoon ,  Kwang Woo Lee ,  Yoon Seok Oh ,  Jang Hee Park

IPC分类号： C12N15/77

CPC分类号： C12N15/77 ,  C12N9/0026 ,  C12P19/32 ,  C12Y105/99008 ,  Y02P20/582

摘要： The present invention relates to a microorganism with improved production of 5′-xanthosine monophosphate and 5′-guanine monophosphate, and more specifically, to a Corynebacterium sp. microorganism having increased proline dehydrogenase activity compared with an intrinsic activity thereof, a method for producing 5′-xanthosine monophosphate or 5′-guanine monophosphate from the culture medium obtained by culturing the transformed microorganism, and a use of the microorganism for production of 5′-xanthosine monophosphate or 5′-guanine monophosphate.

摘要翻译： 本发明涉及一种具有5'-黄嘌呤一磷酸和5'-鸟嘌呤一磷酸的生产的微生物，更具体地说，涉及一种棒状杆菌属。 与其内在活性相比具有增加的脯氨酸脱氢酶活性的微生物，从通过培养转化的微生物获得的培养基中生产5'-黄嘌呤一磷酸或5'-鸟嘌呤一磷酸的方法，以及该微生物用于生产5' 单磷酸黄烷磷酸酯或5'-鸟嘌呤单磷酸酯。

公开(公告)号：US20110250651A1

公开(公告)日：2011-10-13

申请号：US13140302

申请日：2009-12-17

申请人： Jinman Cho ,  Hye Won Kim ,  Yoon Seok Oh

发明人： Jinman Cho ,  Hye Won Kim ,  Yoon Seok Oh

IPC分类号： C12P19/32 ,  C12N1/21

CPC分类号： C12P19/32 ,  C12N9/0006 ,  Y02P20/582

摘要： Disclosed is a method of producing 5′-guanosine monophosphate using a novel microorganism which has a malate dehydrogenase activity higher than that of a wild-type, thereby showing improved ATP productivity. Also, a novel microorganism is disclosed. The method comprises: culturing the corynebacteria strain which is enhanced in malate dehydrogenase activity over the endogenous activity, thus producing ATP in high yield; producing XMP in the culture; adding to the culture an enzyme or microorganism having XMP amination activity; and obtaining GMP from the culture.

摘要翻译： 公开了一种使用具有比野生型高的苹果酸脱氢酶活性的新型微生物生产5'-鸟苷酸单磷酸酯的方法，从而显示出提高的ATP生产率。 另外，公开了一种新型微生物。 该方法包括：培养在内源性活性中苹果酸脱氢酶活性增强的棒状杆菌菌株，从而以高产率产生ATP; 在文化中生产XMP; 向培养基中加入具有XMP胺化活性的酶或微生物; 并从文化中获得GMP。

公开(公告)号：US08034602B2

公开(公告)日：2011-10-11

申请号：US12309048

申请日：2007-07-12

申请人： Young Hoon Park ,  Hye Won Kim ,  Ji-Hye Lee ,  Soo-Youn Hwang

发明人： Young Hoon Park ,  Hye Won Kim ,  Ji-Hye Lee ,  Soo-Youn Hwang

IPC分类号： C12N1/20 ,  C12P13/10

CPC分类号： C12R1/15 ,  C12P13/10

摘要： Disclosed herein are a microorganism producing L-arginine and a method of producing L-arginine using the same. The microorganism is a mutant strain of the genus Corynebacterium, Corynebacterium glutamicum CJR0500. The method for L-arginine production comprises activating the mutant strain C. glutamicum CJR0500 in a fermentation medium at 30° C. for 16 hours and then culturing the activated mutant strain for 72 hours with shaking.

摘要翻译： 本文公开了生产L-精氨酸的微生物和使用其的L-精氨酸的生产方法。 微生物是棒状杆菌属（Corynebacterium），谷氨酸棒杆菌（Corynebacterium glutamicum）CJR0500的突变菌株。 L-精氨酸生产方法包括在30℃的发酵培养基中活化突变菌株C.谷氨酸棒杆菌CJR0500 16小时，然后摇动培养活化的突变菌株72小时。

公开(公告)号：US07682814B2

公开(公告)日：2010-03-23

申请号：US10582389

申请日：2004-11-18

申请人： Young Hoon Park ,  Kwang Myung Cho ,  Hye Won Kim ,  Dae Chol Kim

发明人： Young Hoon Park ,  Kwang Myung Cho ,  Hye Won Kim ,  Dae Chol Kim

IPC分类号： C12N1/00 ,  C12N1/20

CPC分类号： C12N1/20 ,  C12P7/56 ,  C12R1/225

摘要： The present invention relates to a method for producing lactic acid with high concentration and high yield using Lactobacillus paracasei CJLA0310 KCCM-10542 that is separated and identified from Kimchi. Lactic acid is a very important organic acid with a wide range of applications including food additive such as food preservative, condiment or acidifier, and industrial fields such as cosmetics, chemistry, metals, electronics, fabrics, dyeing textiles, and pharmaceutical industries. Particularly, lactic acid is an essential ingredient of polylactic acid, one of biodegradable plastics to replace recalcitrant non-biodegradable plastics which are main causes of environmental contamination.

摘要翻译： 本发明涉及使用从泡菜分离鉴定的副干酪乳杆菌CJLA0310 KCCM-10542来生产高浓度和高产量的乳酸的方法。 乳酸是一种非常重要的有机酸，适用范围广泛，包括食品添加剂如食品防腐剂，调味品或酸化剂，以及化妆品，化学，金属，电子，织物，染色纺织品和制药工业等工业领域。 特别地，乳酸是聚乳酸的重要成分，聚乳酸是能够替代作为环境污染的主要原因的顽固性不可生物降解塑料的生物降解塑料之一。

公开(公告)号：US20070117193A1

公开(公告)日：2007-05-24

申请号：US10582389

申请日：2004-11-18

申请人： Young Park ,  Kwang Cho ,  Hye Won Kim ,  Dae Chol Kim

发明人： Young Park ,  Kwang Cho ,  Hye Won Kim ,  Dae Chol Kim

IPC分类号： C12P7/56 ,  C12N1/20

CPC分类号： C12N1/20 ,  C12P7/56 ,  C12R1/225

摘要： The present invention relates to a method for producing lactic acid with high concentration and high yield using Lactobacillus paracasei CJLA0310 KCCM-10542 that is separated and identified from Kimchi. Lactic acid is a very important organic acid with a wide range of applications including food additive such as food preservative, condiment or acidifier, and industrial fields such as cosmetics, chemistry, metals, electronics, fabrics, dyeing textiles, and pharmaceutical industries. Particularly, lactic acid is an essential ingredient of polylactic acid, one of biodegradable plastics to replace recalcitrant non-biodegradable plastics which are main causes of environmental contamination.

摘要翻译： 本发明涉及使用从泡菜分离鉴定的副干酪乳杆菌CJLA0310 KCCM-10542来生产高浓度和高产量的乳酸的方法。 乳酸是一种非常重要的有机酸，适用范围广泛，包括食品添加剂如食品防腐剂，调味品或酸化剂，以及化妆品，化学，金属，电子，织物，染色纺织品和制药工业等工业领域。 特别地，乳酸是聚乳酸的重要成分，聚乳酸是能够替代作为环境污染的主要原因的顽固性不可生物降解塑料的生物降解塑料之一。

公开(公告)号：US08815545B2

公开(公告)日：2014-08-26

申请号：US13140321

申请日：2009-12-17

申请人： Jinman Cho ,  Hye Won Kim ,  Jinman Lee ,  Ji-Hye Lee ,  Yoon Seok Oh ,  Jang Hee Park

发明人： Jinman Cho ,  Hye Won Kim ,  Jinman Lee ,  Ji-Hye Lee ,  Yoon Seok Oh ,  Jang Hee Park

IPC分类号： C12P19/30 ,  C12N1/12 ,  C12N9/04 ,  C12P19/32

CPC分类号： C12N9/0006 ,  C12P19/32

摘要： Disclosed is a novel microorganism which has a malate dehydrogenase activity higher than that of a wild-type. Also, a recombinant vector which has the structure shown in the cleavage map of FIG. 1, a Corynebacteria strain transformed therewith, and a method of producing 5′-xanthosine monophosphate by culturing the transformed strain are disclosed.

摘要翻译： 公开了具有比野生型高的苹果酸脱氢酶活性的新型微生物。 此外，具有图1的切割图所示结构的重组载体。 1，通过转化的棒状杆菌菌株和通过培养转化菌株来生产5'-芒硝单磷酸的方法。

公开(公告)号：US20130045511A1

公开(公告)日：2013-02-21

申请号：US13310536

申请日：2011-12-02

申请人： Hye Won Kim ,  Ji-Hye Lee ,  Soo Youn Hwang ,  Jong Hyun Kim

发明人： Hye Won Kim ,  Ji-Hye Lee ,  Soo Youn Hwang ,  Jong Hyun Kim

IPC分类号： C12P13/08 ,  C12N1/21

CPC分类号： C12R1/15 ,  C12P13/08

摘要： The present invention relates to a microorganism having an enhanced L-valine productivity and a method for producing L-valine using the same. More particularly, the present invention relates to a Corynebacterium glutamicum mutant strain that has resistance to L-valine and derivatives thereof so as to have an enhanced L-valine productivity, and a method for producing L-valine using the same.

摘要翻译： 本发明涉及具有增强的L-缬氨酸生产力的微生物和使用其的L-缬氨酸生产方法。 更具体地，本发明涉及对L-缬氨酸及其衍生物具有抗性的L-缬氨酸生产力提高的谷氨酸棒杆菌突变菌株和使用其的L-缬氨酸生产方法。

公开(公告)号：US20110117220A1

公开(公告)日：2011-05-19

申请号：US12944775

申请日：2010-11-12

申请人： Hyun Seo Kang ,  Hye Won Kim ,  Chan Koo Kang ,  Sung A. Cho ,  Jun Cheol Cho ,  Sang Hoon Han

发明人： Hyun Seo Kang ,  Hye Won Kim ,  Chan Koo Kang ,  Sung A. Cho ,  Jun Cheol Cho ,  Sang Hoon Han

IPC分类号： A61K36/82 ,  A61K36/00 ,  A61K36/899

CPC分类号： A61K36/82 ,  A61K36/899 ,  A61K36/8994

摘要： The present invention relates to a method of preparing a plant extract using a high-pressure enzymatic decomposition technique (HPED technique) and to a cosmetic composition containing the prepared plant extract as an active ingredient. The plant extract prepared using the high-pressure enzymatic decomposition technique developed according to the present invention contains various kinds and large amounts of effective components compared to extracts prepared using other extraction techniques, such that the effects of the effective components can be maximized.

摘要翻译： 本发明涉及使用高压酶分解技术（HPED技术）制备植物提取物的方法和含有所制备的植物提取物作为活性成分的化妆品组合物。 使用根据本发明开发的高压酶分解技术制备的植物提取物与使用其它提取技术制备的提取物相比含有多种和大量的有效成分，使得有效成分的效果可以最大化。