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    L-ORNITHINE OR L-ARGININE PRODUCING STRAIN AND METHOD FOR PRODUCING L-ORNITHINE OR L-ARGININE
    3.
    发明申请
    L-ORNITHINE OR L-ARGININE PRODUCING STRAIN AND METHOD FOR PRODUCING L-ORNITHINE OR L-ARGININE 有权
    生产L-赖氨酸或L-阿奇霉素的方法和生产L-赖氨酸或L-阿魏酸的方法

    公开(公告)号：US20130023016A1

    公开(公告)日：2013-01-24

    申请号：US13512956

    申请日：2010-12-29

    申请人： Jin-Man Cho ,  Hye-Won Kim ,  Ji-Hye Lee ,  Jae-Yong Cho

    发明人： Jin-Man Cho ,  Hye-Won Kim ,  Ji-Hye Lee ,  Jae-Yong Cho

    IPC分类号： C12N9/10 ,  C12P13/10 ,  C12N1/21 ,  C12N15/54 ,  C12N15/77

    CPC分类号： C12P13/10 ,  C12N9/1029 ,  C12N9/80 ,  C12Y203/01001 ,  C12Y305/01016

    摘要： The present invention relates to a polynucleotide that is active to an acetyl glutamate synthase and acetyl ornithinase which are associated with ornithine or arginine biosynthesis from Corynebacterium glutamicum. The present invention also relates to a polypeptide encoded by said polynucleotide, a recombinant vector comprising said polynucleotide, to a transformant obtained by introducing said recombinant vector to a host microorganism for producing L-ornithine or L-arginine, and transforming the recombinant vector, and to a method for producing L-ornithine or L-arginine by culturing said transformant. The activity of the transformant of the present invention to an acetyl glutamate synthase and acetyl ornithinase is increased as compared to an intrinsic activity, and thus L-ornithine or L-arginine can be produced, at a high yield rate, from the transformant of the present invention.

    摘要翻译： 本发明涉及与谷氨酸棒杆菌的鸟氨酸或精氨酸生物合成相关的乙酰谷氨酸合成酶和乙酰鸟氨酸酶有活性的多核苷酸。 本发明还涉及由所述多核苷酸编码的多肽，包含所述多核苷酸的重组载体，通过将所述重组载体导入宿主微生物以产生L-鸟氨酸或L-精氨酸而获得的转化体，并转化重组载体，以及 涉及通过培养所述转化体生产L-鸟氨酸或L-精氨酸的方法。 与内在活性相比，本发明的转化体对乙酰谷氨酸合成酶和乙酰鸟氨酸酶的活性增加，因此L-鸟氨酸或L-精氨酸可以高产率从 本发明。

    Corynebacteria Strain for Enhancement of 5'-Guanosine Monophosphate Productivity and a Method of Producing 5'-Guanosine Monophosphate Using the Same
    6.
    发明申请
    Corynebacteria Strain for Enhancement of 5'-Guanosine Monophosphate Productivity and a Method of Producing 5'-Guanosine Monophosphate Using the Same 有权
    用于增强5'-鸟苷一磷酸生产力的棒状杆菌菌株及使用其制备5'-鸟苷酸单磷酸酯的方法

    公开(公告)号：US20110250651A1

    公开(公告)日：2011-10-13

    申请号：US13140302

    申请日：2009-12-17

    申请人： Jinman Cho ,  Hye Won Kim ,  Yoon Seok Oh

    发明人： Jinman Cho ,  Hye Won Kim ,  Yoon Seok Oh

    IPC分类号： C12P19/32 ,  C12N1/21

    CPC分类号： C12P19/32 ,  C12N9/0006 ,  Y02P20/582

    摘要： Disclosed is a method of producing 5′-guanosine monophosphate using a novel microorganism which has a malate dehydrogenase activity higher than that of a wild-type, thereby showing improved ATP productivity. Also, a novel microorganism is disclosed. The method comprises: culturing the corynebacteria strain which is enhanced in malate dehydrogenase activity over the endogenous activity, thus producing ATP in high yield; producing XMP in the culture; adding to the culture an enzyme or microorganism having XMP amination activity; and obtaining GMP from the culture.

    摘要翻译： 公开了一种使用具有比野生型高的苹果酸脱氢酶活性的新型微生物生产5'-鸟苷酸单磷酸酯的方法，从而显示出提高的ATP生产率。 另外，公开了一种新型微生物。 该方法包括：培养在内源性活性中苹果酸脱氢酶活性增强的棒状杆菌菌株，从而以高产率产生ATP; 在文化中生产XMP; 向培养基中加入具有XMP胺化活性的酶或微生物; 并从文化中获得GMP。

    Method for producing L-arginine using Corynebacterium glutamicum
    7.
    发明授权
    Method for producing L-arginine using Corynebacterium glutamicum 有权
    使用谷氨酸棒杆菌生产L-精氨酸的方法

    公开(公告)号：US08034602B2

    公开(公告)日：2011-10-11

    申请号：US12309048

    申请日：2007-07-12

    申请人： Young Hoon Park ,  Hye Won Kim ,  Ji-Hye Lee ,  Soo-Youn Hwang

    发明人： Young Hoon Park ,  Hye Won Kim ,  Ji-Hye Lee ,  Soo-Youn Hwang

    IPC分类号： C12N1/20 ,  C12P13/10

    CPC分类号： C12R1/15 ,  C12P13/10

    摘要： Disclosed herein are a microorganism producing L-arginine and a method of producing L-arginine using the same. The microorganism is a mutant strain of the genus Corynebacterium, Corynebacterium glutamicum CJR0500. The method for L-arginine production comprises activating the mutant strain C. glutamicum CJR0500 in a fermentation medium at 30° C. for 16 hours and then culturing the activated mutant strain for 72 hours with shaking.

    摘要翻译： 本文公开了生产L-精氨酸的微生物和使用其的L-精氨酸的生产方法。 微生物是棒状杆菌属（Corynebacterium），谷氨酸棒杆菌（Corynebacterium glutamicum）CJR0500的突变菌株。 L-精氨酸生产方法包括在30℃的发酵培养基中活化突变菌株C.谷氨酸棒杆菌CJR0500 16小时，然后摇动培养活化的突变菌株72小时。

    Method for producing lactic acid with high concentration and high yield using lactic acid bacteria
    8.
    发明授权
    Method for producing lactic acid with high concentration and high yield using lactic acid bacteria 有权
    使用乳酸菌生产高浓度和高产量乳酸的方法

    公开(公告)号：US07682814B2

    公开(公告)日：2010-03-23

    申请号：US10582389

    申请日：2004-11-18

    申请人： Young Hoon Park ,  Kwang Myung Cho ,  Hye Won Kim ,  Dae Chol Kim

    发明人： Young Hoon Park ,  Kwang Myung Cho ,  Hye Won Kim ,  Dae Chol Kim

    IPC分类号： C12N1/00 ,  C12N1/20

    CPC分类号： C12N1/20 ,  C12P7/56 ,  C12R1/225

    摘要： The present invention relates to a method for producing lactic acid with high concentration and high yield using Lactobacillus paracasei CJLA0310 KCCM-10542 that is separated and identified from Kimchi. Lactic acid is a very important organic acid with a wide range of applications including food additive such as food preservative, condiment or acidifier, and industrial fields such as cosmetics, chemistry, metals, electronics, fabrics, dyeing textiles, and pharmaceutical industries. Particularly, lactic acid is an essential ingredient of polylactic acid, one of biodegradable plastics to replace recalcitrant non-biodegradable plastics which are main causes of environmental contamination.

    摘要翻译： 本发明涉及使用从泡菜分离鉴定的副干酪乳杆菌CJLA0310 KCCM-10542来生产高浓度和高产量的乳酸的方法。 乳酸是一种非常重要的有机酸，适用范围广泛，包括食品添加剂如食品防腐剂，调味品或酸化剂，以及化妆品，化学，金属，电子，织物，染色纺织品和制药工业等工业领域。 特别地，乳酸是聚乳酸的重要成分，聚乳酸是能够替代作为环境污染的主要原因的顽固性不可生物降解塑料的生物降解塑料之一。