公开(公告)号：US07289838B2

公开(公告)日：2007-10-30

申请号：US10942091

申请日：2004-09-16

申请人： Kye-jin Jeon ,  In-duk Hwang ,  Eun-young Choe ,  Hye-jeong Kim

发明人： Kye-jin Jeon ,  In-duk Hwang ,  Eun-young Choe ,  Hye-jeong Kim

IPC分类号： A61B5/00

CPC分类号： A61B5/1455 ,  A61B5/14532 ,  A61B5/6826 ,  A61B5/6838

摘要： A blood component measuring apparatus includes a fixing apparatus for fixing a body part of an examinee, the body part including a tissue to be examined, a light source portion for radiating light onto the tissue to be examined, the tissue to be examined covering the light source portion, a photodetector for detecting light passing through the tissue to be examined, the photodetector facing the light source portion, and an analyzer for analyzing the light detected by the photodetector, wherein the fixing apparatus includes first and second fixing members for fixing first and second portions of the body part, respectively, the first and second portions of the body part being connected to the tissue to be examined, wherein the first and second fixing members are operable to move depending on a location of the tissue to be examined.

摘要翻译： 血液成分测量装置包括用于固定受检者的身体部分的定影装置，包括待检查组织的身体部分，用于将光照射到待检查组织上的光源部分，覆盖光的被检查组织 源极部分，用于检测通过待检查组织的光的光电检测器，面向光源部分的光电检测器和用于分析由光电检测器检测到的光的分析器，其中定影装置包括用于首先固定的第一和第二固定构件 主体部分的第二部分分别与主体部分的第一和第二部分连接到待检查的组织，其中第一和第二固定部件可操作以根据被检查组织的位置移动。

公开(公告)号：US07107087B2

公开(公告)日：2006-09-12

申请号：US10801612

申请日：2004-03-17

申请人： In-duk Hwang ,  Gil-won Yoon ,  Sang-joon Han ,  Kye-jin Jeon

发明人： In-duk Hwang ,  Gil-won Yoon ,  Sang-joon Han ,  Kye-jin Jeon

IPC分类号： A61B5/00 ,  G01J3/42

CPC分类号： A61B5/1455 ,  A61B5/14532 ,  G01J3/1256 ,  G01N21/31

摘要： A method of measuring a concentration of a component in a subject includes setting an intensity relationship equation between a positive-order beam and a negative-order beam with respect to a reference matter at a particular wavelength, applying a light having a first wavelength band absorbed by the component and detecting an intensity of a positive-order beam output from the subject and an intensity of a negative-order beam output from the reference matter, the positive-order beam and the negative-order beam having a second wavelength band, calculating an intensity of a positive-order beam input to the subject by applying the intensity of the negative-order beam output from the reference matter to the intensity relationship equation, and calculating absorbance using the intensity of the positive-order beam output from the subject and the intensity of the positive-order beam input to the subject and measuring a concentration of the component using the absorbance.

摘要翻译： 测定被检体内成分浓度的方法包括：在特定波长下设定正序光束与负光束之间的强度关系方程式，将具有吸收的第一波长带的光 通过分量并检测从对象输出的正阶光束的强度和从参考物质输出的负光束的强度，正阶光束和负光束具有第二波长带，计算 通过将从参考物质输出的负光束的强度施加到强度关系式来输入到对象的正阶光束的强度，并且使用从被摄体输出的正阶光束的强度来计算吸光度，以及 输入到对象的正阶光束的强度，并使用吸光度测量成分的浓度。

公开(公告)号：US06944571B2

公开(公告)日：2005-09-13

申请号：US10667131

申请日：2003-09-22

申请人： Sangjoon Hahn ,  Haemin Cho ,  Gilwon Yoon ,  Kye-jin Jeon ,  In-duk Hwang

发明人： Sangjoon Hahn ,  Haemin Cho ,  Gilwon Yoon ,  Kye-jin Jeon ,  In-duk Hwang

IPC分类号： G01N21/25 ,  G01J3/28 ,  G01N21/31 ,  G06F19/00 ,  G06F15/00

CPC分类号： G01N21/31 ,  G01J3/28 ,  G01N2021/3129

摘要： A method of estimating a pure spectrum and a concentration of each component constituting n sample mixtures, in which p kinds of components are mixed, includes (a) performing a principal component analysis of the spectra of the n mixtures, which are measured using m wavelengths, to represent the spectra of the n mixtures as factors and scores of the respective factors, wherein n, p, and m are integers and m>p, and (b) performing an independent component analysis of the scores obtained in (a) to estimate the pure spectra and the concentrations of the respective components.

摘要翻译： 估计构成混合了p种成分的n种样品混合物的各组分的纯谱和浓度的方法包括（a）对使用m个波长测量的n种混合物的光谱进行主成分分析 表示n个混合物的光谱作为各个因子的因子和得分，其中n，p和m是整数，m> p，和（b）对（a）至（b）中获得的分数进行独立分量分析 估计各个组分的纯谱和浓度。

公开(公告)号：US20050154268A1

公开(公告)日：2005-07-14

申请号：US11002136

申请日：2004-12-03

申请人： In-duk Hwang ,  Wan-taek Han ,  Kye-jin Jeon ,  Kun-kook Park ,  Eun-young Choe ,  Hyun-tai Hwang

发明人： In-duk Hwang ,  Wan-taek Han ,  Kye-jin Jeon ,  Kun-kook Park ,  Eun-young Choe ,  Hyun-tai Hwang

IPC分类号： A61B5/145 ,  A61B5/00 ,  G01J3/18 ,  G01N21/35 ,  G01N33/48

CPC分类号： G01N21/359 ,  A61B5/14532 ,  A61B5/1455 ,  G01J3/0232 ,  G01J3/18

摘要： A body component concentration measuring apparatus, and method, for measuring a concentration of a body component in a measuring portion of a living body, includes a light source for emitting light, a diffraction grating being movable to disperse light emitted from the light source into light components having a plurality of wavelength bands, a shutter for controlling transmission of the light components having the plurality of wavelength bands, a lens for focusing the light components passing the shutter onto the measuring portion, and a detector for detecting the light components passing through the measuring portion.

摘要翻译： 用于测量生物体的测量部分中的身体成分的浓度的身体成分浓度测量装置和方法包括用于发射光的光源，衍射光栅可移动以将从光源发射的光分散成光 具有多个波长带的部件，用于控制具有多个波长带的光分量的传输的快门，用于将通过快门的光分量聚焦到测量部分上的透镜，以及用于检测通过 测量部分。

公开(公告)号：US6026314A

公开(公告)日：2000-02-15

申请号：US149219

申请日：1998-09-08

申请人： Airat K. Amerov ,  Kye-jin Jeon ,  Yoen-joo Kim ,  Gil-won Yoon

发明人： Airat K. Amerov ,  Kye-jin Jeon ,  Yoen-joo Kim ,  Gil-won Yoon

IPC分类号： A61B5/145 ,  A61B5/00 ,  A61B5/1455

CPC分类号： A61B5/1455 ,  A61B5/14532 ,  A61B5/14546

摘要： A method and device for noninvasive measurement of blood component concentrations utilizes pulsed polychromatic light source emitting, light in the near infrared range 800-1850 nm. The light is back scattered from or transmitted through a part of a patient's body. Back scattered light from blood-containing tissues and blood vessels has information on blood component concentrations. That light is collected to avoid the surface reflection from the skin surface and to minimize the effects of changes in the scattering background. The concentrations of blood components are calculated from the spectral analysis based on selected wavelengths by a defined algorithm. A microprocessor calculates and determines the blood component concentrations by comparing a ratio with a calibration curve stored in a memory of the microprocessor. The calculated concentration values are displayed on a display.

摘要翻译： 用于非侵入性测量血液成分浓度的方法和装置利用发射近红外范围800-1850nm的光的脉冲多色光源。 光从背部散开或通过患者身体的一部分传播。 来自血液的组织和血管的背散射光具有关于血液成分浓度的信息。 收集该光以避免来自皮肤表面的表面反射并使散射背景中的变化的影响最小化。 血液成分的浓度由基于所选择的波长的光谱分析通过定义的算法计算。 微处理器通过将比率与存储在微处理器的存储器中的校准曲线进行比较来计算和确定血液成分浓度。 计算出的浓度值显示在显示屏上。

公开(公告)号：US07266402B2

公开(公告)日：2007-09-04

申请号：US11311381

申请日：2005-12-20

申请人： Kye-jin Jeon ,  Ji-deog Kim ,  In-duk Hwang

发明人： Kye-jin Jeon ,  Ji-deog Kim ,  In-duk Hwang

IPC分类号： A61B5/00

CPC分类号： A61B5/14532

摘要： Provided are an apparatus and a method for determining blood sugar level without blood using dark adaptation of the optic nerve, and a computer-readable recording medium storing a computer program performing the method. The apparatus irradiates stimulating light onto the pupil of a subject. A detecting device determines when the subject responds to the light. A calculator then calculates the blood sugar based on the response to the stimulating light.

摘要翻译： 本发明提供了一种使用视神经暗适应度来测定血液中血糖水平的装置和方法，以及存储执行该方法的计算机程序的计算机可读记录介质。 该装置将刺激光照射到受试者的瞳孔上。 检测装置确定对象何时对光进行响应。 然后，计算器基于对刺激光的响应来计算血糖。

公开(公告)号：US20060167352A1

公开(公告)日：2006-07-27

申请号：US11311381

申请日：2005-12-20

申请人： Kye-jin Jeon ,  Ji-deog Kim ,  In-duk Hwang

发明人： Kye-jin Jeon ,  Ji-deog Kim ,  In-duk Hwang

IPC分类号： A61B5/00

CPC分类号： A61B5/14532

摘要： Provided are an apparatus and a method for determining blood sugar level without blood using dark adaptation of the optic nerve, and a computer-readable recording medium storing a computer program performing the method. The apparatus irradiates stimulating light onto the pupil of a subject. A detecting device determines when the subject responds to the light. A calculator then calculates the blood sugar based on the response to the stimulating light.

摘要翻译： 本发明提供了一种使用视神经暗适应度来测定血液中血糖水平的装置和方法，以及存储执行该方法的计算机程序的计算机可读记录介质。 该装置将刺激光照射到受试者的瞳孔上。 检测装置确定对象何时对光进行响应。 然后，计算器基于对刺激光的响应来计算血糖。

公开(公告)号：US06921366B2

公开(公告)日：2005-07-26

申请号：US10390614

申请日：2003-03-19

申请人： Kye-jin Jeon ,  Gil-won Yoon ,  In-duk Hwang

发明人： Kye-jin Jeon ,  Gil-won Yoon ,  In-duk Hwang

IPC分类号： G01N29/00 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1455 ,  A61B8/00 ,  G01N21/00 ,  G01N21/17 ,  G01N21/49

CPC分类号： A61B5/1455 ,  A61B5/0059 ,  A61B5/0095 ,  A61B5/14532 ,  G01N21/1702 ,  G01N21/49 ,  G01N2021/1706

摘要： An apparatus and method for non-invasively measuring bio-fluid concentrations using photoacoustic spectroscopy includes a light source for irradiating an incident light having a predetermined wavelength band to be absorbed into a targeted component of a living body, an acoustic signal generator for generating a first acoustic signal having a similar frequency band as a photoacoustic signal that is generated when the incident light is absorbed into the targeted component, a ultrasonic translator for detecting the photoacoustic signal and a second acoustic signal that is a modulated signal of the first acoustic signal, a controller for generating the first acoustic signal in a predetermined frequency band, a light detector for detecting an intensity of the incident light, and a calculator capable of calculating a signal compensation value based on the incident light, the photoacoustic signal, and the coefficient of sound wave transmission, and capable of computing a concentration of the targeted component.

摘要翻译： 使用光声波光谱法非侵入性地测量生物流体浓度的装置和方法包括用于将具有预定波长带的入射光照射以吸收到生物体的目标组分中的光源;声信号发生器，用于产生第一 声光信号具有与入射光被吸收到目标成分中时产生的光声信号相似的频带，用于检测光声信号的超声波转换器和作为第一声信号的调制信号的第二声信号， 用于产生预定频带中的第一声信号的控制器，用于检测入射光强度的光检测器和能够基于入射光，光声信号和声系数计算信号补偿值的计算器 波传输，并能计算浓度 目标组件。