公开(公告)号：US07248911B2

公开(公告)日：2007-07-24

申请号：US10802920

申请日：2004-03-18

申请人： Kye-jin Jeon ,  Gil-won Yoon ,  In-duk Hwang ,  Sang-joon Han

发明人： Kye-jin Jeon ,  Gil-won Yoon ,  In-duk Hwang ,  Sang-joon Han

IPC分类号： A61B5/00

CPC分类号： A61B5/14532 ,  A61B5/0053 ,  A61B5/107 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1495 ,  A61B2560/0223 ,  G01N21/359 ,  G01N2021/036 ,  G01N2021/3144 ,  G01N2201/0662

摘要： In an apparatus and method of noninvasively measuring a concentration of a blood component, the method includes (a) varying a thickness of a body part of a subject, measuring absorption spectrums at different thicknesses of the body part, obtaining a first differential absorption spectrum between the absorption spectrums measured at different thicknesses, actually measuring concentrations of the blood component, and establishing a statistical model using the first differential absorption spectrum and the actually measured concentrations; and (b) estimating the concentration of the blood component using a second differential absorption spectrum obtained with respect to the body part based on the statistical model.

摘要翻译： 在非侵入性地测量血液成分浓度的装置和方法中，该方法包括：（a）改变被检体的身体部位的厚度，测量身体部位的不同厚度的吸收光谱，获得第一差异吸收光谱， 在不同厚度下测量的吸收光谱，实际测量血液成分的浓度，并使用第一个差示吸收光谱和实际测量的浓度建立统计模型; 和（b）基于统计模型使用相对于身体部位获得的第二差分吸收光谱估计血液成分的浓度。

公开(公告)号：US07107087B2

公开(公告)日：2006-09-12

申请号：US10801612

申请日：2004-03-17

申请人： In-duk Hwang ,  Gil-won Yoon ,  Sang-joon Han ,  Kye-jin Jeon

发明人： In-duk Hwang ,  Gil-won Yoon ,  Sang-joon Han ,  Kye-jin Jeon

IPC分类号： A61B5/00 ,  G01J3/42

CPC分类号： A61B5/1455 ,  A61B5/14532 ,  G01J3/1256 ,  G01N21/31

摘要： A method of measuring a concentration of a component in a subject includes setting an intensity relationship equation between a positive-order beam and a negative-order beam with respect to a reference matter at a particular wavelength, applying a light having a first wavelength band absorbed by the component and detecting an intensity of a positive-order beam output from the subject and an intensity of a negative-order beam output from the reference matter, the positive-order beam and the negative-order beam having a second wavelength band, calculating an intensity of a positive-order beam input to the subject by applying the intensity of the negative-order beam output from the reference matter to the intensity relationship equation, and calculating absorbance using the intensity of the positive-order beam output from the subject and the intensity of the positive-order beam input to the subject and measuring a concentration of the component using the absorbance.

摘要翻译： 测定被检体内成分浓度的方法包括：在特定波长下设定正序光束与负光束之间的强度关系方程式，将具有吸收的第一波长带的光 通过分量并检测从对象输出的正阶光束的强度和从参考物质输出的负光束的强度，正阶光束和负光束具有第二波长带，计算 通过将从参考物质输出的负光束的强度施加到强度关系式来输入到对象的正阶光束的强度，并且使用从被摄体输出的正阶光束的强度来计算吸光度，以及 输入到对象的正阶光束的强度，并使用吸光度测量成分的浓度。

公开(公告)号：US06995931B2

公开(公告)日：2006-02-07

申请号：US10831121

申请日：2004-04-26

申请人： In-duk Hwang ,  Gil-won Yoon ,  Kye-jin Jeon

发明人： In-duk Hwang ,  Gil-won Yoon ,  Kye-jin Jeon

IPC分类号： G02B7/02

CPC分类号： G01J5/061 ,  F25B21/02 ,  H01L23/38 ,  H01L2924/0002 ,  H01L2924/00

摘要： A temperature controlled optoelectronic device includes an optoelectronic transducer having an active area, an electronic cooling device, on which the optoelectronic transducer is mounted, and a temperature sensor installed in the electronic cooling device. The temperature sensor and the electronic cooling device control a temperature of the optoelectronic transducer. A surface of an electronic cooling device directly contacts a base of the optoelectronic transducer for efficient thermal coupling. When the temperature sensor for monitoring the temperature of the optoelectronic transducer is directly attached to a substrate of the electronic cooling device, e.g., to an inside surface of a plate on which the optoelectronic transducer is mounted, the temperature of the optoelectronic transducer can be accurately sensed and adjusted to a precise target temperature.

摘要翻译： 温度控制的光电子器件包括具有有源区的光电转换器，安装光电变换器的电子冷却装置和安装在电子冷却装置中的温度传感器。 温度传感器和电子冷却装置控制光电传感器的温度。 电子冷却装置的表面直接接触光电转换器的基座，用于有效的热耦合。 当用于监测光电转换器的温度的温度传感器直接连接到电子冷却装置的基板上时，例如直接安装在其上安装光电转换器的板的内表面上，光电转换器的温度可以准确地 感测并调整到精确的目标温度。

公开(公告)号：US06921366B2

公开(公告)日：2005-07-26

申请号：US10390614

申请日：2003-03-19

申请人： Kye-jin Jeon ,  Gil-won Yoon ,  In-duk Hwang

发明人： Kye-jin Jeon ,  Gil-won Yoon ,  In-duk Hwang

IPC分类号： G01N29/00 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1455 ,  A61B8/00 ,  G01N21/00 ,  G01N21/17 ,  G01N21/49

CPC分类号： A61B5/1455 ,  A61B5/0059 ,  A61B5/0095 ,  A61B5/14532 ,  G01N21/1702 ,  G01N21/49 ,  G01N2021/1706

摘要： An apparatus and method for non-invasively measuring bio-fluid concentrations using photoacoustic spectroscopy includes a light source for irradiating an incident light having a predetermined wavelength band to be absorbed into a targeted component of a living body, an acoustic signal generator for generating a first acoustic signal having a similar frequency band as a photoacoustic signal that is generated when the incident light is absorbed into the targeted component, a ultrasonic translator for detecting the photoacoustic signal and a second acoustic signal that is a modulated signal of the first acoustic signal, a controller for generating the first acoustic signal in a predetermined frequency band, a light detector for detecting an intensity of the incident light, and a calculator capable of calculating a signal compensation value based on the incident light, the photoacoustic signal, and the coefficient of sound wave transmission, and capable of computing a concentration of the targeted component.

摘要翻译： 使用光声波光谱法非侵入性地测量生物流体浓度的装置和方法包括用于将具有预定波长带的入射光照射以吸收到生物体的目标组分中的光源;声信号发生器，用于产生第一 声光信号具有与入射光被吸收到目标成分中时产生的光声信号相似的频带，用于检测光声信号的超声波转换器和作为第一声信号的调制信号的第二声信号， 用于产生预定频带中的第一声信号的控制器，用于检测入射光强度的光检测器和能够基于入射光，光声信号和声系数计算信号补偿值的计算器 波传输，并能计算浓度 目标组件。

公开(公告)号：US20050124916A1

公开(公告)日：2005-06-09

申请号：US11002306

申请日：2004-12-03

申请人： Jong-youn Lee ,  Sang-joon Han ,  Kye-jin Jeon ,  In-duk Hwang ,  Hye-jin Jung

发明人： Jong-youn Lee ,  Sang-joon Han ,  Kye-jin Jeon ,  In-duk Hwang ,  Hye-jin Jung

IPC分类号： A61B8/06 ,  A61B5/00 ,  A61B17/20 ,  B01D15/08 ,  B65D81/00 ,  C02F1/28

CPC分类号： A61B5/15134 ,  A61B5/0002 ,  A61B5/14514 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150946 ,  A61B5/157 ,  A61B5/6887

摘要： In a mobile terminal having a skin permeation device, and an apparatus and a method for analyzing a body fluid using the same, the skin permeation device includes a control unit for outputting an oscillation start signal in response to an input signal, an oscillating unit for receiving the oscillation start signal and for outputting an oscillation signal having a predetermined frequency, and an output unit for outputting an ultrasonic signal to a diagnosis region of a user in response to the oscillation signal, the output unit being operable to perform skin permeation.

摘要翻译： 在具有皮肤渗透装置的移动终端和使用其的体液分析装置和方法中，皮肤渗透装置包括用于响应于输入信号输出振荡开始信号的控制单元，用于 接收所述振荡开始信号并输出​​具有预定频率的振荡信号;以及输出单元，用于响应于所述振荡信号将超声信号输出到用户的诊断区域，所述输出单元可操作以进行皮肤渗透。

公开(公告)号：US20050119538A1

公开(公告)日：2005-06-02

申请号：US10942091

申请日：2004-09-16

申请人： Kye-jin Jeon ,  In-duk Hwang ,  Eun-young Choe ,  Hye-jeong Kim

发明人： Kye-jin Jeon ,  In-duk Hwang ,  Eun-young Choe ,  Hye-jeong Kim

IPC分类号： G01N21/27 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1455 ,  G01N21/35 ,  G01N21/3577 ,  G01N21/359 ,  A61B5/05

CPC分类号： A61B5/1455 ,  A61B5/14532 ,  A61B5/6826 ,  A61B5/6838

摘要： A blood component measuring apparatus includes a fixing apparatus for fixing a body part of an examinee, the body part including a tissue to be examined, a light source portion for radiating light onto the tissue to be examined, the tissue to be examined covering the light source portion, a photodetector for detecting light passing through the tissue to be examined, the photodetector facing the light source portion, and an analyzer for analyzing the light detected by the photodetector, wherein the fixing apparatus includes first and second fixing members for fixing first and second portions of the body part, respectively, the first and second portions of the body part being connected to the tissue to be examined, wherein the first and second fixing members are operable to move depending on a location of the tissue to be examined.

摘要翻译： 血液成分测量装置包括用于固定受检者的身体部分的定影装置，包括待检查组织的身体部分，用于将光照射到待检查组织上的光源部分，覆盖光的被检查组织 源极部分，用于检测通过待检查组织的光的光电检测器，面向光源部分的光电检测器和用于分析由光电检测器检测到的光的分析器，其中定影装置包括用于首先固定的第一和第二固定构件 主体部分的第二部分分别与主体部分的第一和第二部分连接到待检查的组织，其中第一和第二固定部件可操作以根据被检查组织的位置移动。

公开(公告)号：US07289838B2

公开(公告)日：2007-10-30

申请号：US10942091

申请日：2004-09-16

申请人： Kye-jin Jeon ,  In-duk Hwang ,  Eun-young Choe ,  Hye-jeong Kim

发明人： Kye-jin Jeon ,  In-duk Hwang ,  Eun-young Choe ,  Hye-jeong Kim

IPC分类号： A61B5/00

CPC分类号： A61B5/1455 ,  A61B5/14532 ,  A61B5/6826 ,  A61B5/6838

摘要： A blood component measuring apparatus includes a fixing apparatus for fixing a body part of an examinee, the body part including a tissue to be examined, a light source portion for radiating light onto the tissue to be examined, the tissue to be examined covering the light source portion, a photodetector for detecting light passing through the tissue to be examined, the photodetector facing the light source portion, and an analyzer for analyzing the light detected by the photodetector, wherein the fixing apparatus includes first and second fixing members for fixing first and second portions of the body part, respectively, the first and second portions of the body part being connected to the tissue to be examined, wherein the first and second fixing members are operable to move depending on a location of the tissue to be examined.

摘要翻译： 血液成分测量装置包括用于固定受检者的身体部分的定影装置，包括待检查组织的身体部分，用于将光照射到待检查组织上的光源部分，覆盖光的被检查组织 源极部分，用于检测通过待检查组织的光的光电检测器，面向光源部分的光电检测器和用于分析由光电检测器检测到的光的分析器，其中定影装置包括用于首先固定的第一和第二固定构件 主体部分的第二部分分别与主体部分的第一和第二部分连接到待检查的组织，其中第一和第二固定部件可操作以根据被检查组织的位置移动。

公开(公告)号：US06944571B2

公开(公告)日：2005-09-13

申请号：US10667131

申请日：2003-09-22

申请人： Sangjoon Hahn ,  Haemin Cho ,  Gilwon Yoon ,  Kye-jin Jeon ,  In-duk Hwang

发明人： Sangjoon Hahn ,  Haemin Cho ,  Gilwon Yoon ,  Kye-jin Jeon ,  In-duk Hwang

IPC分类号： G01N21/25 ,  G01J3/28 ,  G01N21/31 ,  G06F19/00 ,  G06F15/00

CPC分类号： G01N21/31 ,  G01J3/28 ,  G01N2021/3129

摘要： A method of estimating a pure spectrum and a concentration of each component constituting n sample mixtures, in which p kinds of components are mixed, includes (a) performing a principal component analysis of the spectra of the n mixtures, which are measured using m wavelengths, to represent the spectra of the n mixtures as factors and scores of the respective factors, wherein n, p, and m are integers and m>p, and (b) performing an independent component analysis of the scores obtained in (a) to estimate the pure spectra and the concentrations of the respective components.

摘要翻译： 估计构成混合了p种成分的n种样品混合物的各组分的纯谱和浓度的方法包括（a）对使用m个波长测量的n种混合物的光谱进行主成分分析 表示n个混合物的光谱作为各个因子的因子和得分，其中n，p和m是整数，m> p，和（b）对（a）至（b）中获得的分数进行独立分量分析 估计各个组分的纯谱和浓度。

公开(公告)号：US20050159658A1

公开(公告)日：2005-07-21

申请号：US11038023

申请日：2005-01-21

申请人： Kye-jin Jeon ,  Jong-youn Lee ,  In-duk Hwang ,  Kun-kook Park ,  Hye-jeong Kim ,  Hye-jin Jung ,  Eun-young Choe

发明人： Kye-jin Jeon ,  Jong-youn Lee ,  In-duk Hwang ,  Kun-kook Park ,  Hye-jeong Kim ,  Hye-jin Jung ,  Eun-young Choe

IPC分类号： A61B5/145 ,  A61B5/00

CPC分类号： A61B5/6825 ,  A61B5/14532 ,  A61B5/1491 ,  A61B5/6833 ,  A61B5/6843

摘要： In a non-invasive body component measuring apparatus for measuring a concentration of a body component in a measuring portion of a living body, and a method of non-invasively measuring the concentration of the body component, the non-invasive body component measuring apparatus includes a light source unit for generating light of a predetermined wavelength and for applying the light onto the measuring portion, a detection unit for detecting light reflected or transmitted by the measuring portion and for converting the detected light into an electrical signal, a signal processing unit for processing the electrical signal, and a body-apparatus interface unit for fixing a periphery of the measuring portion during measurement.

摘要翻译： 在一种用于测量生物体的测量部分中的身体成分的浓度的非侵入性体成分测量装置和非侵入性地测量身体成分的浓度的方法中，非侵入性身体成分测量装置包括 光源单元，用于产生预定波长的光并将光施加到测量部分;检测单元，用于检测由测量部分反射或透射的光并将检测到的光转换成电信号;信号处理单元，用于 处理电信号，以及体测设备接口单元，用于在测量期间固定测量部分的周边。

公开(公告)号：US07310542B2

公开(公告)日：2007-12-18

申请号：US11038023

申请日：2005-01-21

申请人： Kye-jin Jeon ,  Jong-youn Lee ,  In-duk Hwang ,  Kun-kook Park ,  Hye-jeong Kim ,  Hye-jin Jung ,  Eun-young Choe

发明人： Kye-jin Jeon ,  Jong-youn Lee ,  In-duk Hwang ,  Kun-kook Park ,  Hye-jeong Kim ,  Hye-jin Jung ,  Eun-young Choe

IPC分类号： A61B5/00

CPC分类号： A61B5/6825 ,  A61B5/14532 ,  A61B5/1491 ,  A61B5/6833 ,  A61B5/6843

摘要： In a non-invasive body component measuring apparatus for measuring a concentration of a body component in a measuring portion of a living body, and a method of non-invasively measuring the concentration of the body component, the non-invasive body component measuring apparatus includes a light source unit for generating light of a predetermined wavelength and for applying the light onto the measuring portion, a detection unit for detecting light reflected or transmitted by the measuring portion and for converting the detected light into an electrical signal, a signal processing unit for processing the electrical signal, and a body-apparatus interface unit for fixing a periphery of the measuring portion during measurement.

摘要翻译： 在一种用于测量生物体的测量部分中的身体成分的浓度的非侵入性体成分测量装置和非侵入性地测量身体成分的浓度的方法中，非侵入性身体成分测量装置包括 光源单元，用于产生预定波长的光并将光施加到测量部分;检测单元，用于检测由测量部分反射或透射的光并将检测到的光转换成电信号;信号处理单元，用于 处理电信号，以及体测设备接口单元，用于在测量期间固定测量部分的周边。