公开(公告)号：US20080263904A1

公开(公告)日：2008-10-30

申请号：US12164654

申请日：2008-06-30

申请人： Wolfgang Scholz

发明人： Wolfgang Scholz

IPC分类号： A43B5/00 ,  A43B23/20 ,  A43C15/00

CPC分类号： A43B5/02 ,  A43B3/24 ,  A43B3/246 ,  A43C15/161

摘要： A modular shoe includes an upper with an upper side and a lower side, a chassis releasably arranged in an interior of the upper, and a plurality of studs. Each stud is releasably attached to the chassis through the lower side of the upper. The lower side of the upper is clamped between the chassis and at least one of the attached studs. The invention also relates to the various components used in a modular shoe in accordance with the invention.

摘要翻译： 模块化鞋包括具有上侧和下侧的鞋面，可拆卸地布置在鞋帮的内部的底座和多个螺柱。 每个螺柱通过上部的下侧可释放地附接到底盘。 上部的下侧夹在底盘和至少一个附接的螺柱之间。 本发明还涉及根据本发明的模块化鞋中使用的各种部件。

公开(公告)号：US07406781B2

公开(公告)日：2008-08-05

申请号：US11064439

申请日：2005-02-23

申请人： Wolfgang Scholz

发明人： Wolfgang Scholz

IPC分类号： A43C15/16

CPC分类号： A43B5/02 ,  A43B3/24 ,  A43B3/246 ,  A43C15/161

摘要： A modular shoe includes an upper with an upper side and a lower side, a chassis releasably arranged in an interior of the upper, and a plurality of studs. Each stud is releasably attached to the chassis through the lower side of the upper. The lower side of the upper is clamped between the chassis and at least one of the attached studs. The invention also relates to the various components used in a modular shoe in accordance with the invention.

摘要翻译： 模块化鞋包括具有上侧和下侧的鞋面，可拆卸地布置在鞋帮的内部的底座和多个螺柱。 每个螺柱通过上部的下侧可释放地附接到底盘。 上部的下侧夹在底盘和至少一个附接的螺柱之间。 本发明还涉及根据本发明的模块化鞋中使用的各种部件。

公开(公告)号：US20080154436A1

公开(公告)日：2008-06-26

申请号：US12000527

申请日：2007-12-13

申请人： Peter Krippner ,  Thomas Kleegrewe ,  Armin Gasch ,  Detlef Pape ,  Wolfgang Lasarzik ,  Wolfgang Scholz ,  Urs E. Meier

发明人： Peter Krippner ,  Thomas Kleegrewe ,  Armin Gasch ,  Detlef Pape ,  Wolfgang Lasarzik ,  Wolfgang Scholz ,  Urs E. Meier

IPC分类号： F15B21/08 ,  G05D7/06 ,  G05B19/04

CPC分类号： G05D7/0635 ,  Y10T137/7759

摘要： The disclosure relates to a control device for a pneumatically operated actuator in the field of process automation, in particular for continuous control of material flows in the industrial environment. The control device has a communications interface for receiving an electrical setpoint value, and an output for the output of a pneumatic fluid, whose pressure is varied as a function of a control deviation. The received electrical setpoint value is suitable as a process parameter. The control device is connected via a communications channel to an actual-value encoder, which is designed to output an electrical signal corresponding to the actual value of the same process parameter.

摘要翻译： 本公开涉及一种用于过程自动化领域的气动操纵致动器的控制装置，特别是用于在工业环境中连续控制材料流动。 控制装置具有用于接收电气设定点值的通信接口和用于输出作为控制偏差的函数的气动流体的输出的输出。 接收的电气设定值适合作为过程参数。 控制装置经由通信信道连接到实际值编码器，其被设计为输出与相同处理参数的实际值相对应的电信号。

公开(公告)号：US20080063647A1

公开(公告)日：2008-03-13

申请号：US11041318

申请日：2005-01-24

申请人： Phillip R. Morrow ,  Angray S. Kang ,  Fei Wang ,  Ivy Jiang ,  Ritsuko Sawada ,  Wolfgang Scholz ,  Jeanne Morrow

发明人： Phillip R. Morrow ,  Angray S. Kang ,  Fei Wang ,  Ivy Jiang ,  Ritsuko Sawada ,  Wolfgang Scholz ,  Jeanne Morrow

IPC分类号： A61K39/40 ,  C07K16/12

CPC分类号： C07K16/1278 ,  A61K39/40 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/56 ,  C07K2317/76 ,  C07K2317/92 ,  A61K2300/00

摘要： A highly efficient method for generating human antibodies using recall technology is provided. In one aspect, human antibodies which are specific to the anthrax toxin are provided. In one aspect, human peripheral blood cells that have been pre-exposed to anthrax toxin are used in the SCID mouse model. This method results in high human antibody titers which are primarily of the IgG isotype and which contain antibodies of high specificity and affinity to desired antigens. The antibodies generated by this method can be used therapeutically and prophylactically for preventing or treating mammals exposed to anthrax. Thus, in one embodiment, a prophylactic or therapeutic agent used to counter the effects of anthrax toxin, released as a mechanism of bioterrorism, is provided. In one embodiment, a formulation and method for preventing and/or treating anthrax infection comprising a binding agent that prevents the assembly of the PA63 heptamer is also provided. Methods for diagnosis and methods to determine anthrax contamination are also described.

摘要翻译： 提供了使用召回技术产生人抗体的高效方法。 一方面，提供了对炭疽毒素特异性的人抗体。 一方面，在SCID小鼠模型中使用预先暴露于炭疽毒素的人外周血细胞。 该方法导致高的人抗体滴度，其主要是IgG同种型，并且其含有对所需抗原具有高特异性和亲和力的抗体。 通过该方法产生的抗体可以治疗和预防用于预防或治疗暴露于炭疽的哺乳动物。 因此，在一个实施方案中，提供了用作抵抗作为生物恐怖机制的机制释放的炭疽毒素的作用的预防或治疗剂。 在一个实施方案中，还提供了用于预防和/或治疗炭疽感染的制剂和方法，其包含阻止PA 63七聚体组装的结合剂。 还描述了诊断方法和确定炭疽污染的方法。

公开(公告)号：US20050198868A1

公开(公告)日：2005-09-15

申请号：US11064439

申请日：2005-02-23

申请人： Wolfgang Scholz

发明人： Wolfgang Scholz

IPC分类号： A43B3/24 ,  A43B5/02 ,  A43B17/00 ,  A43B23/02 ,  A43C15/02 ,  A43C15/16 ,  A43B5/00

CPC分类号： A43B5/02 ,  A43B3/24 ,  A43B3/246 ,  A43C15/161

摘要： A modular shoe includes an upper with an upper side and a lower side, a chassis releasably arranged in an interior of the upper, and a plurality of studs. Each stud is releasably attached to the chassis through the lower side of the upper. The lower side of the upper is clamped between the chassis and at least one of the attached studs. The invention also relates to the various components used in a modular shoe in accordance with the invention.

摘要翻译： 模块化鞋包括具有上侧和下侧的鞋面，可拆卸地布置在鞋帮的内部的底座和多个螺柱。 每个螺柱通过上部的下侧可释放地附接到底盘。 上部的下侧夹在底盘和至少一个附接的螺柱之间。 本发明还涉及根据本发明的模块化鞋中使用的各种部件。

公开(公告)号：US20050193833A1

公开(公告)日：2005-09-08

申请号：US10958232

申请日：2004-10-06

申请人： Dirk Huybrechts ,  Paul Szasz ,  Dominik Eifel ,  Eniet Asaah ,  Hans-Werner Schwiderski ,  Andreas Thone ,  Ralf Huck ,  Wolfgang Scholz ,  Fabrizio Lorito ,  Albrecht Vogel

发明人： Dirk Huybrechts ,  Paul Szasz ,  Dominik Eifel ,  Eniet Asaah ,  Hans-Werner Schwiderski ,  Andreas Thone ,  Ralf Huck ,  Wolfgang Scholz ,  Fabrizio Lorito ,  Albrecht Vogel

IPC分类号： G01F1/58 ,  G01K13/02

CPC分类号： G01F1/588

摘要： The invention relates to a magnetic-inductive measuring device (1) for flowing substances (substance being measured), with a measuring tube (2) and a further subsystem respectively for recording measuring signals, comprising a signal pickup (electrode arrangement (20, 22) for signal tapping), for generating a magnetic field, comprising at least two exciting coils (30) and a ferromagnetic core (32) (magnetic system), and for bounding the device on the ambient side (housing), and is characterized in that at least one of the further subsystems is entirely or partly formed by a casting compound and/or embedded in a casting compound.

摘要翻译： 本发明涉及一种用于流动物质（被测量物质）的磁感应测量装置（1），分别具有用于记录测量信号的测量管（2）和另外的子系统，其包括信号拾取器（20,22 ），用于产生包括至少两个励磁线圈（30）和铁磁芯（32）（磁性系统）的磁场，并且用于在环境侧（壳体）上限制该装置，并且其特征在于 至少其中一个子系统完全或部分地由铸造化合物形成和/或嵌入到铸塑料中。

公开(公告)号：US06598482B2

公开(公告)日：2003-07-29

申请号：US10172131

申请日：2002-06-14

申请人： Wolfgang Scholz ,  Albrecht Vogel ,  Peter Krippner

发明人： Wolfgang Scholz ,  Albrecht Vogel ,  Peter Krippner

IPC分类号： G01L1500

CPC分类号： G01L19/0627 ,  G01L13/026 ,  G01L19/0618

摘要： A differential pressure sensor has a first and a second measuring chamber. Each measuring chamber is limited by a rigid carrier plate and a diaphragm plate, which is formed in the region of the measuring chamber as a pressure-sensitive measuring diaphragm. To design the differential pressure sensor to be resistant to overloading, the carrier plate is arranged between a first and a second diaphragm plate and has congruent concave depressions on opposite sides in the plane of the plate. The depressions are connected to one another by a decentered duct, penetrating the carrier plate perpendicularly to the plane of the plates. In the region of the measuring chambers, the diaphragm plates are formed congruently in relation to the depressions as pressure-sensitive measuring diaphragms. The measuring chambers and the duct are filled with an incompressible fluid.

摘要翻译： 差压传感器具有第一和第二测量室。 每个测量室由刚性载体板和隔膜板限制，该板在测量室的区域中形成为压敏测量膜片。 为了设计差压传感器以防止过载，承载板布置在第一和第二隔膜板之间，并且在板的平面的相对侧上具有一致的凹陷。 凹陷通过偏心的管道相互连接，垂直于板的平面穿透载体板。 在测量室的区域中，隔板相对于凹陷形成为压敏测量隔膜。 测量室和管道填充有不可压缩流体。

公开(公告)号：US06568275B2

公开(公告)日：2003-05-27

申请号：US10172275

申请日：2002-06-14

申请人： Wolfgang Scholz ,  Albrecht Vogel ,  Peter Krippner ,  Dieter Binz

发明人： Wolfgang Scholz ,  Albrecht Vogel ,  Peter Krippner ,  Dieter Binz

IPC分类号： G01L912

CPC分类号： G01L9/0073

摘要： There is described a capacitive differential pressure sensor made using glass-silicon technology with a diaphragm plate of silicon, which is arranged between two carrier plates consisting of glass. The diaphragm plate has pressure-sensitively deflectable regions, which are respectively provided with a capacitor arrangement. The capacitor arrangement is connected to a measured-value processing device through connecting conductors. To improve the ratio of the measuring capacitances to the parasitic capacitances brought about by the connecting conductors, the diaphragm plate is outside the pressure-sensitively deflectable region the substrate of an electronic circuit which comprises at least one input stage of the measured-value processing device.

公开(公告)号：US06536288B2

公开(公告)日：2003-03-25

申请号：US10172132

申请日：2002-06-14

申请人： Wolfgang Scholz ,  Albrecht Vogel ,  Peter Krippner ,  Dieter Binz

发明人： Wolfgang Scholz ,  Albrecht Vogel ,  Peter Krippner ,  Dieter Binz

IPC分类号： G01L912

CPC分类号： G01L9/0073

摘要： There is described a differential pressure sensor made using glass-silicon technology with a diaphragm plate arranged between two carrier plates. To achieve a high resolution at the beginning of the measuring range in conjunction with high overload resistance, the measuring diaphragm plate of the sensor has for a prescribed measuring range within the same measuring chambers a plurality of mutually independent deflectable regions as measuring diaphragms. Each such region acts as a part-sensor with a part-measuring range. The part-measuring ranges of the part-sensors overlap and in total are equal to the prescribed measuring range of the differential pressure sensor. The displacement of the measuring diaphragm of each part-sensor is mechanically limited outside its part-measuring range by the carrier plates.

公开(公告)号：US6075054A

公开(公告)日：2000-06-13

申请号：US28474

申请日：1998-02-24

申请人： Andreas Weichert ,  Joachim Brendel ,  Heinz-Werner Kleemann ,  Hans Jochen Lang ,  Jan-Robert Schwark ,  Udo Albus ,  Wolfgang Scholz

发明人： Andreas Weichert ,  Joachim Brendel ,  Heinz-Werner Kleemann ,  Hans Jochen Lang ,  Jan-Robert Schwark ,  Udo Albus ,  Wolfgang Scholz

IPC分类号： A61K31/155 ,  A61K31/165 ,  A61P3/06 ,  A61P9/00 ,  A61P9/06 ,  A61P9/10 ,  A61P11/00 ,  A61P13/02 ,  A61P15/00 ,  A61P25/00 ,  A61P35/00 ,  C07C279/10 ,  C07C279/20 ,  C07C279/22

CPC分类号： C07C279/22

摘要： Benzoylguanidines of formula I ##STR1## with R(1) to R(4) as defined in the specification, are suitable as antiarrhythmic pharmaceuticals having a cardioprotective component for infarct prophylaxis and infarct treatment as well as for the treatment of angina pectoris.They inhibit, in a preventive manner, the pathophysiological processes in the formation of ischemically induced damage, in particular in the elicitation of ischemically induced cardiac arrhythmias.

摘要翻译： 具有本说明书中定义的R（1）至R（4）的式I的苯甲酰基胍适合作为具有用于梗塞预防和梗死治疗的心脏保护组分以及用于治疗心绞痛的抗心律失常药物。 它们以预防的方式抑制形成缺血诱导的损伤的病理生理过程，特别是在缺血诱导的心律失常的引发中。