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公开(公告)号：US20100038530A1
公开(公告)日：2010-02-18
申请号：US11813221
申请日：2006-01-17
申请人： Kevin Giles , Martin Green , Jason Lee Wildgoose
发明人： Kevin Giles , Martin Green , Jason Lee Wildgoose
CPC分类号： H01J49/4235 , H01J49/4275
摘要： An ion guide or ion trap (1) is disclosed comprising a segmented linear ion guide or ion trap. Ions are confined radially within the ion guide or ion trap (1) by the application of an AC or RF voltage to the electrodes. A static potential well is maintained along at least a portion of the axial length of the ion guide or ion trap (1). A time varying homogeneous electric field is applied along at least a portion of the axial length of the ion guide or ion trap (1). The combination of the static axial potential well and the time varying axial homogeneous electric field causes ions to be ejected from the ion guide or ion trap (1) in a substantially non-resonant manner.
摘要翻译： 公开了一种离子导向器或离子阱（1），其包括分段线性离子导向器或离子阱。 通过向电极施加AC或RF电压，离子在径向上被限制在离子导向器或离子阱（1）内。 沿离子导向器或离子阱（1）的轴向长度的至少一部分保持静电势阱。 沿离子导向器或离子阱（1）的轴向长度的至少一部分施加时变均匀电场。 静态轴向势阱和随时间变化的轴向均匀电场的组合导致离子以基本上非共振的方式从离子导向器或离子阱（1）喷出。
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公开(公告)号：US20100032561A1
公开(公告)日：2010-02-11
申请号：US12518291
申请日：2007-12-12
IPC分类号： H01J49/26
CPC分类号： G01N27/622 , G01N27/624 , H01J49/062 , H01J49/4235
摘要： A mass spectrometer is disclosed comprising a device (2) which is operable in a first mode of operation to separate ions temporally according to their ion mobility by applying a continuous axial electric field. The device (2) is also operable in a second mode of operation wherein ions are separated temporally according to the their mass to charge ratio by pulsing an applied axial electric field ON and OFF.
摘要翻译： 公开了一种质谱仪，其包括可在第一操作模式中操作的装置（2），其通过施加连续轴向电场根据其离子迁移率暂时分离离子。 装置（2）还可在第二操作模式中操作，其中通过脉冲施加的轴向电场ON和OFF，离子根据其质荷比逐时分离。
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公开(公告)号：US09281172B2
公开(公告)日：2016-03-08
申请号：US12094561
申请日：2006-12-07
CPC分类号： G01N27/622 , H01J49/062
摘要： A closed-loop ion guide is disclosed comprising a plurality of electrodes having apertures through which ions are transmitted in use. Ions are injected into the closed-loop ion guide and may make several circuits of the closed-loop ion guide before being ejected from the ion guide. In a mode of operation the ion guide may be arranged to separate ions temporally according to their ion mobility.
摘要翻译： 公开了一种闭环离子导向器，其包括具有孔的多个电极，在使用中通过该孔具有离子。 离子被注入到闭环离子导向器中，并且可以在从离子导向器喷射之前使闭环离子导向器的几个电路。 在一种操作模式中，离子导向器可以根据其离子迁移率临时分离离子。
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公开(公告)号：US20150294850A1
公开(公告)日：2015-10-15
申请号：US14240586
申请日：2012-08-22
申请人： Kevin Giles , Martin Raymond Green , Daniel James Kenny , David J. Langridge , Jason Lee Wildgoose
发明人： Kevin Giles , Martin Raymond Green , Daniel James Kenny , David J. Langridge , Jason Lee Wildgoose
CPC分类号： H01J49/4285 , H01J49/0031 , H01J49/062 , H01J49/063 , H01J49/40 , H01J49/422
摘要： A mass or mass to charge ratio selective ion trap is disclosed which directs ions into a small ejection region. A RF voltage acts to confine ions in a first (y) direction within the ion trap. A DC or RF voltage acts to confine ions in a second (x) direction. A quadratic DC potential well acts to confine ions in a third (z) direction within the ion trap. The profile of the quadratic DC potential well progressively varies along the second (x) direction.
摘要翻译： 公开了将离子引导到小的喷射区域中的质量或质量比的选择性离子阱。 RF电压用于将离子限制在离子阱内的第一（y）方向。 DC或RF电压用于将离子限制在第二（x）方向。 二次直流势阱用于将离子限制在离子阱内的第三（z）方向。 二次直流电势的曲线沿着第二（x）方向逐渐变化。
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公开(公告)号：US08952323B2
公开(公告)日：2015-02-10
申请号：US12092601
申请日：2006-11-10
CPC分类号： H01J49/004 , G01N27/622 , H01J49/0031 , H01J49/42
摘要： A mass spectrometer is disclosed comprising a first ion trap or ion guide (2), a single ion mobility spectrometer or separator stage (3) and a second ion trap or ion guide (4) arranged downstream of the ion mobility spectrometer or separator (3). In a mode of operation ions from the second ion trap or ion guide (4) are passed from the second ion trap or ion guide back upstream to the ion mobility spectrometer or separator (3).
摘要翻译： 公开了一种质谱仪，其包括第一离子阱或离子导向器（2），单离子迁移谱仪或分离器级（3）和设置在离子迁移谱仪或分离器（3）的下游的第二离子阱或离子导向器 ）。 在操作模式中，来自第二离子阱或离子导向器（4）的离子从第二离子阱或离子导向器返回到离子迁移谱仪或分离器（3）的上游。
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公开(公告)号：US08946626B2
公开(公告)日：2015-02-03
申请号：US14240667
申请日：2012-08-22
申请人： Kevin Giles , Martin Raymond Green , Daniel James Kenny , David J. Langridge , Jason Lee Wildgoose
发明人： Kevin Giles , Martin Raymond Green , Daniel James Kenny , David J. Langridge , Jason Lee Wildgoose
CPC分类号： H01J49/424 , H01J49/421 , H01J49/422 , H01J49/4285
摘要： A mass or mass to charge ratio selective ion trap is disclosed having an increased charge storage capacity. A RF voltage acts to confine ions in a first (y) direction within the ion trap. A DC voltage and/or an RF voltage acts to confine ions in a second (x) direction within the ion trap. A quadratic DC potential well acts to confine ions in a third (z) direction within the ion trap. Ions are excited in the third (z) direction and are caused to be mass or mass to charge ratio selectively ejected in the third (z) direction.
摘要翻译： 公开了具有增加的电荷存储容量的质量或质量 - 电荷比选择性离子阱。 RF电压用于将离子限制在离子阱内的第一（y）方向。 DC电压和/或RF电压用于将离子限制在离子阱内的第二（x）方向。 二次直流势阱用于将离子限制在离子阱内的第三（z）方向。 离子在第三（z）方向上被激发，并且被导致在第三（z）方向上选择性地喷射的质量或质量 - 充电比。
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公开(公告)号：US08519328B2
公开(公告)日：2013-08-27
申请号：US13435877
申请日：2012-03-30
IPC分类号： H01J49/26
CPC分类号： H01J49/427 , H01J49/4235
摘要： An ion guide or ion trap is disclosed having an entrance electrode and an exit electrode. The potential of the exit electrode is periodically dropped for a relatively short period of time allowing some ions to escape from the ion guide or ion trap via an aperture in the exit electrode. The period of time that the potential of the exit electrode is dropped for is progressively increased and ions emerge from the ion guide or ion trap in a mass to charge ratio dependent manner. The ion guide or ion trap may be operated as a mass separator or low resolution mass analyzer.
摘要翻译： 公开了一种具有入口电极和出射电极的离子导向器或离子阱。 出口电极的电位周期性地下降相当短的时间段，允许一些离子通过出射电极的孔离开离子导向器或离子阱。 出口电极的电位下降的时间段逐渐增加，并且离子导向器或离子阱以质荷比依赖的方式出现离子。 离子导向器或离子阱可以作为质量分离器或低分辨率质量分析器来操作。
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公开(公告)号：US08426802B2
公开(公告)日：2013-04-23
申请号：US12518291
申请日：2007-12-12
CPC分类号： G01N27/622 , G01N27/624 , H01J49/062 , H01J49/4235
摘要： A mass spectrometer is disclosed comprising a device which is operable in a first mode of operation to separate ions temporally according to their ion mobility by applying a continuous axial electric field. The device is also operable in a second mode of operation wherein ions are separated temporally according to the their mass to charge ratio by pulsing an applied axial electric field ON and OFF.
摘要翻译： 公开了一种质谱仪，其包括可在第一操作模式中操作的装置，其通过施加连续的轴向电场根据其离子迁移率暂时分离离子。 该装置还可在第二操作模式中操作，其中通过脉冲施加的轴向电场ON和OFF，离子根据其质荷比暂时分离。
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公开(公告)号：US20110042565A1
公开(公告)日：2011-02-24
申请号：US12917720
申请日：2010-11-02
IPC分类号： H01J49/40
CPC分类号： G01N27/622 , H01J49/0027 , H01J49/0031 , H01J49/004 , H01J49/0045 , H01J49/02 , H01J49/062 , H01J49/065 , H01J49/066 , H01J49/40 , H01J49/401 , H01J49/42
摘要： A mass spectrometer is disclosed comprising an ion mobility spectrometer or separator 4 and an ion guide 6 arranged downstream of the ion mobility spectrometer or separator 4. A plurality of axial potential wells are created in the ion guide 6 so that ions received from the ion mobility spectrometer or separator 4 become confined in separate axial potential wells. The potential wells maintain the fidelity and/or composition of ions received from the ion mobility spectrometer or separator 4. The potential wells are translated along the length of the ion guide 6.
摘要翻译： 公开了一种质谱仪，其包括离子迁移谱仪或分离器4和布置在离子迁移谱仪或分离器4下游的离子导向器6.在离子导向器6中产生多个轴向势阱，使得从离子迁移率 光谱仪或分离器4被限制在单独的轴向势阱中。 势阱保持从离子迁移谱仪或分离器4接收的离子的保真度和/或组成。势阱沿离子导向器6的长度平移。
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公开(公告)号：US07829841B2
公开(公告)日：2010-11-09
申请号：US11718213
申请日：2005-11-03
CPC分类号： G01N27/622 , H01J49/0027 , H01J49/0031 , H01J49/004 , H01J49/0045 , H01J49/02 , H01J49/062 , H01J49/065 , H01J49/066 , H01J49/40 , H01J49/401 , H01J49/42
摘要： A mass spectrometer is disclosed comprising an ion mobility spectrometer or separator (4) and an ion guide (6) arranged downstream of the ion mobility spectrometer or separator (4). A plurality of axial potential wells are created in the ion guide (6) so that ions received from the ion mobility spectrometer or separator (4) become confined in separate axial potential wells. The potential wells maintain the fidelity and/or composition of ions received from the ion mobility spectrometer or separator (4). The potential wells are translated along the length of the ion guide (6).
摘要翻译： 公开了一种质谱仪，其包括离子迁移谱仪或分离器（4）和布置在离子迁移谱仪或分离器（4）的下游的离子导向器（6）。 在离子导向器（6）中产生多个轴向势阱，使得从离子迁移谱仪或分离器（4）接收的离子被限制在单独的轴向势阱中。 潜在的孔维持从离子迁移谱仪或分离器（4）接收的离子的保真度和/或组成。 潜在的井沿离子导向件（6）的长度平移。
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