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183 条记录 (耗时 0.049 秒)

    Drug releasing coatings for medical devices
    13.
    发明授权
    Drug releasing coatings for medical devices 有权

    公开(公告)号：US08244344B2

    公开(公告)日：2012-08-14

    申请号：US13272432

    申请日：2011-10-13

    申请人： Lixiao Wang

    发明人： Lixiao Wang

    IPC分类号： A61M37/00 ,  A61M25/10 ,  A61B18/20

    CPC分类号： A61L31/16 ,  A61K31/337 ,  A61K31/436 ,  A61L29/16 ,  A61L31/08 ,  A61L2300/416 ,  A61L2300/80 ,  A61L2300/802 ,  A61K2300/00

    摘要： The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent and an additive. In certain embodiments, the additive has a hydrophilic part and a drug affinity part, wherein the drug affinity part is at least one of a hydrophobic part, a part that has an affinity to the therapeutic agent by hydrogen bonding, and a part that has an affinity to the therapeutic agent by van der Waals interactions. In embodiments, the additive is water-soluble. In further embodiments, the additive is at least one of a surfactant and a chemical compound, and the chemical compound has a molecular weight of from 80 to 750 or has more than four hydroxyl groups.

    Catheter having an improved balloon-to-catheter bond
    14.
    发明授权
    Catheter having an improved balloon-to-catheter bond 有权
    导管具有改善的气球与导管接合

    公开(公告)号：US07914486B2

    公开(公告)日：2011-03-29

    申请号：US10764405

    申请日：2004-01-23

    申请人： John Chen ,  Nie Tang ,  Ed Parsonage ,  Paul Miller ,  Lixiao Wang

    发明人： John Chen ,  Nie Tang ,  Ed Parsonage ,  Paul Miller ,  Lixiao Wang

    IPC分类号： A61M29/00

    CPC分类号： A61L29/04 ,  A61L29/06 ,  A61M25/10 ,  A61M25/1034 ,  C08L77/00 ,  C08L67/02

    摘要： A balloon catheter assembly includes a first tubular member with a proximal portion and a distal portion and a lumen extending between the proximal portion and the distal portion. A balloon has a proximal waist length, a distal waist length and an expandable region therebetween disposed about the distal portion. A tie layer is disposed between the proximal waist length or distal waist length and the first tubular member. The tie layer comprises a polyester polymer and a polyamide polymer.

    摘要翻译： 球囊导管组件包括具有近端部分和远端部分的第一管状部件和在近端部分和远端部分之间延伸的内腔。 气球具有近端腰部长度，远端腰围长度和围绕远侧部分设置的可扩张区域。 连接层设置在近端腰部长度或远端腰部长度与第一管状部件之间。 连结层包含聚酯聚合物和聚酰胺聚合物。

    Expandable ablation burr
    20.
    发明授权
    Expandable ablation burr 失效
    可扩展消融毛刺

    公开(公告)号：US07252674B2

    公开(公告)日：2007-08-07

    申请号：US10770336

    申请日：2004-02-02

    申请人： Mark H. Wyzgala ,  Eric B. Hamilton ,  Tom J. Hiblar ,  Lixiao Wang ,  John J. Chen ,  Irina Nazarova ,  Nancy L. Haig ,  Sheng-Ping Zhong

    发明人： Mark H. Wyzgala ,  Eric B. Hamilton ,  Tom J. Hiblar ,  Lixiao Wang ,  John J. Chen ,  Irina Nazarova ,  Nancy L. Haig ,  Sheng-Ping Zhong

    IPC分类号： A61B17/32

    CPC分类号： A61B17/320725 ,  A61B17/320758 ,  A61B2017/00557 ,  A61B2017/00867 ,  A61B2017/320004 ,  A61B2017/320733

    摘要： An atherectomy burr has an operating diameter that is larger than the diameter of a catheter in which the burr is routed. The burr may include an expandable polymeric balloon having a partially abrasive exterior surface. The maximum expansion of the burr is controlled by an expansion mechanism. Various mechanisms are disclosed for controlling the maximum diameter of the burr thus preventing the burr from over expanding. In addition, the present invention includes systems that are pulled proximally to remove portions of a lesion located in a patient's vasculature. The system includes an ablation burr that has abrasive disposed on the proximal end. The burr may create a seal when expanded to block the ablated particulate so that an aspiration system can remove the particulate from the vasculature. Alternatively, the burr system may include a self expanding seal that is deployed out of the aspiration sheath.

    摘要翻译： 粥样斑块切除术毛刺的操作直径大于其中布置毛刺的导管的直径。 毛刺可以包括具有部分研磨外表面的可膨胀聚合气囊。 毛刺的最大膨胀由膨胀机构控制。 公开了用于控制毛刺的最大直径的各种机构，从而防止毛刺过度膨胀。 另外，本发明还包括向近侧拉动以去除位于病人脉管系统中的病变部分的系统。 该系统包括具有设置在近端的磨料的消融毛刺。 当膨胀时，毛刺可以产生密封，以阻止消融的颗粒，使得吸气系统可以从脉管系统中除去颗粒。 或者，毛刺系统可以包括从抽吸鞘部署出来的自膨胀密封件。