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公开(公告)号：US5882891A
公开(公告)日：1999-03-16
申请号：US898779
申请日：1997-07-23
申请人： Michael Terence Black , John Edward Hodgson , David Justin Charles Knowles , Raymond Winfield Reichard , Richard Oakly Nicholas , Martin Karl Russel Burnham , Julie M Pratt , Martin Rosenberg , Judith M Ward , Michael Arthur Lonetto , Patrick Vernon Warren
发明人： Michael Terence Black , John Edward Hodgson , David Justin Charles Knowles , Raymond Winfield Reichard , Richard Oakly Nicholas , Martin Karl Russel Burnham , Julie M Pratt , Martin Rosenberg , Judith M Ward , Michael Arthur Lonetto , Patrick Vernon Warren
IPC分类号： G01N33/50 , A61K38/00 , A61K39/00 , A61K39/395 , A61K45/00 , A61K48/00 , A61P31/04 , A61P37/00 , C07K14/31 , C07K16/12 , C12N1/21 , C12N9/78 , C12N15/09 , C12N15/31 , C12N15/11 , C12N1/20 , C12N15/63
CPC分类号： C07K16/1275 , C07K14/31 , C12N9/78 , C12Y305/04025 , A61K2039/51 , A61K38/00 , A61K39/00
摘要： The invention provides Ferrichrome transport ATP-Binding Protein polypeptides and DNA (RNA) encoding Ferrichrome transport ATP-Binding Protein polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Ferrichrome transport ATP-Binding Protein polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了Ferrichrome转运ATP结合蛋白多肽和编码Ferrichrome转运ATP结合蛋白多肽的DNA（RNA）和通过重组技术产生此类多肽的方法。 还提供了利用Ferrichrome转运ATP结合蛋白多肽筛选抗菌化合物的方法。
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公开(公告)号：US06323336B1
公开(公告)日：2001-11-27
申请号：US09322081
申请日：1999-05-28
申请人： Michael Terence Black , John Edward Hodgson , David Justin Charles Knowles , Raymond Winfield Reichard , Richard Oakley Nicholas , Martin Karl Russel Burnham , Julie M Pratt , Martin Rosenberg , Judith M Ward , Michael Arthur Lonetto , Patrick Vernon Warren
发明人： Michael Terence Black , John Edward Hodgson , David Justin Charles Knowles , Raymond Winfield Reichard , Richard Oakley Nicholas , Martin Karl Russel Burnham , Julie M Pratt , Martin Rosenberg , Judith M Ward , Michael Arthur Lonetto , Patrick Vernon Warren
IPC分类号： C07H2104
CPC分类号： C07K14/31 , A61K39/00 , C07K16/1275 , C12N9/78 , C12Y305/04025
摘要： The invention provides phoH homolog polypeptides and DNA (RNA) encoding phoH homolog polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing phoH homolog polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供phoH同系物多肽和编码phoH同源多肽的DNA（RNA），以及通过重组技术产生此类多肽的方法。 还提供了利用phoH同源多肽筛选抗菌化合物的方法。
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公开(公告)号：US06248863B1
公开(公告)日：2001-06-19
申请号：US09343986
申请日：1999-06-29
申请人： Michael Terence Black , John Edward Hodgson , David Justin Charles Knowles , Raymond Winfield Reichard , Richard Oakley Nicholas , Martin Karl Russel Burnham , Julie M Pratt , Martin Rosenberg , Judith M Ward , Michael Arthur Lonetto , Patrick Vernon Warren
发明人： Michael Terence Black , John Edward Hodgson , David Justin Charles Knowles , Raymond Winfield Reichard , Richard Oakley Nicholas , Martin Karl Russel Burnham , Julie M Pratt , Martin Rosenberg , Judith M Ward , Michael Arthur Lonetto , Patrick Vernon Warren
IPC分类号： C07K500
CPC分类号： C07K14/31 , A61K39/00 , C07K16/1275 , C12N9/78 , C12Y305/04025
摘要： The invention provides phoH homolog polypeptides and DNA (RNA) encoding phoH homolog polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing phoH homolog polypeptides to screen for anitbacterial compounds.
摘要翻译： 本发明提供phoH同系物多肽和编码phoH同源多肽的DNA（RNA），以及通过重组技术产生此类多肽的方法。 还提供了利用phoH同系物多肽来筛选脱细菌化合物的方法。
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公开(公告)号：US5885805A
公开(公告)日：1999-03-23
申请号：US915107
申请日：1997-08-20
申请人： Michael Arthur Lonetto , Patrick Vernon Warren , Michael Terence Black , John Edward Hodgson , David Justin Charles Knowles , Raymond Winfield Reichard , Richard Oakley Nicholas , Martin Karl Russel Burnham , Julie M Pratt , Martin Rosenberg , Judith M Ward
发明人： Michael Arthur Lonetto , Patrick Vernon Warren , Michael Terence Black , John Edward Hodgson , David Justin Charles Knowles , Raymond Winfield Reichard , Richard Oakley Nicholas , Martin Karl Russel Burnham , Julie M Pratt , Martin Rosenberg , Judith M Ward
IPC分类号： G01N33/50 , A61K31/70 , A61K38/00 , A61K38/04 , A61K38/44 , A61K38/55 , A61K39/00 , A61K39/395 , A61K45/00 , A61K48/00 , A61P31/04 , A61P35/00 , A61P37/00 , A61P37/04 , A61P43/00 , C07K14/31 , C07K16/12 , C12N1/00 , C12N1/21 , C12N9/00 , C12N9/04 , C12N9/12 , C12N9/14 , C12N9/88 , C12N15/00 , C12N15/09 , C12N15/31 , C12N15/53 , C12N15/54 , C12P21/02 , C12P21/08 , C12Q1/02 , C12Q1/68 , C12R1/19 , C12R1/44 , C12R1/445 , G01N33/15 , G01N33/53 , G01N33/569 , G01N33/573 , C12P21/04 , C12N15/63
CPC分类号： C12N9/0006 , C07K14/31 , C12N9/00 , C12N9/1205 , C12N9/88 , A61K38/00 , A61K39/00 , C07K2319/00 , Y10S435/883
摘要： The invention provides gbpA polypeptides and DNA (RNA) encoding gbpA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gbpA polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了gbpA多肽和编码gbpA多肽的DNA（RNA），以及通过重组技术产生此类多肽的方法。 还提供了利用gbpA多肽筛选抗菌化合物的方法。
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公开(公告)号：US5882897A
公开(公告)日：1999-03-16
申请号：US915207
申请日：1997-08-20
申请人： Michael Terence Black , John Edward Hodgson , David Justin Charles Knowles , Raymond Winfield Reichard , Richard Oakley Nicholas , Martin Karl Russel Burnham , Julie M. Pratt , Martin Rosenberg , Judith M Ward , Michael Arthur Lonetto , Patrick Vernon Warren
发明人： Michael Terence Black , John Edward Hodgson , David Justin Charles Knowles , Raymond Winfield Reichard , Richard Oakley Nicholas , Martin Karl Russel Burnham , Julie M. Pratt , Martin Rosenberg , Judith M Ward , Michael Arthur Lonetto , Patrick Vernon Warren
IPC分类号： G01N33/50 , A61K31/70 , A61K38/00 , A61K38/04 , A61K38/44 , A61K38/55 , A61K39/00 , A61K39/395 , A61K45/00 , A61K48/00 , A61P31/04 , A61P35/00 , A61P37/00 , A61P37/04 , A61P43/00 , C07K14/31 , C07K16/12 , C12N1/00 , C12N1/21 , C12N9/00 , C12N9/04 , C12N9/12 , C12N9/14 , C12N9/88 , C12N15/00 , C12N15/09 , C12N15/31 , C12N15/53 , C12N15/54 , C12P21/02 , C12P21/08 , C12Q1/02 , C12Q1/68 , C12R1/19 , C12R1/44 , C12R1/445 , G01N33/15 , G01N33/53 , G01N33/569 , G01N33/573 , C12P21/06 , C07H21/04
CPC分类号： C12N9/0006 , C07K14/31 , C12N9/00 , C12N9/1205 , C12N9/88 , A61K38/00 , A61K39/00 , C07K2319/00 , Y10S435/883
摘要： The invention provides yitJ polypeptides and DNA (RNA) encoding yitJ polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing yitJ polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了yitJ多肽和编码yitJ多肽的DNA（RNA），以及通过重组技术产生此类多肽的方法。 还提供了利用yitJ多肽筛选抗菌化合物的方法。
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公开(公告)号：US6165462A
公开(公告)日：2000-12-26
申请号：US345603
申请日：1999-06-29
申请人： Michael Terence Black , John Edward Hodgson , David Justin Charles Knowles , Raymond Winfield Reichard , Richard Oakley Nicholas , Martin Karl Russel Burnham , Julie M Pratt , Martin Rosenberg , Judith M Ward , Michael Arthur Lonetto , Patrick Vernon Warren
发明人： Michael Terence Black , John Edward Hodgson , David Justin Charles Knowles , Raymond Winfield Reichard , Richard Oakley Nicholas , Martin Karl Russel Burnham , Julie M Pratt , Martin Rosenberg , Judith M Ward , Michael Arthur Lonetto , Patrick Vernon Warren
IPC分类号： G01N33/50 , A61K31/70 , A61K38/00 , A61K38/04 , A61K38/44 , A61K38/55 , A61K39/00 , A61K39/395 , A61K45/00 , A61K48/00 , A61P31/04 , A61P35/00 , A61P37/00 , A61P37/04 , A61P43/00 , C07K14/31 , C07K16/12 , C12N1/00 , C12N1/21 , C12N9/00 , C12N9/04 , C12N9/12 , C12N9/14 , C12N9/88 , C12N15/00 , C12N15/09 , C12N15/31 , C12N15/53 , C12N15/54 , C12P21/02 , C12P21/08 , C12Q1/02 , C12Q1/68 , C12R1/19 , C12R1/44 , C12R1/445 , G01N33/15 , G01N33/53 , G01N33/569 , G01N33/573 , A61K38/51 , C07H21/04 , C12N1/20
CPC分类号： C12N9/0006 , A61K38/00 , A61K39/00 , C07K14/31 , C07K2319/00 , C12N9/00 , C12N9/1205 , C12N9/88 , Y10S435/883
摘要： The invention provides sugar kinase polypeptides and DNA (RNA) encoding sugar kunase polypepties and methods for producing such polypeptides by recombinant techniques. Also provided are methods or utlizng sugar kinase polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供糖激酶多肽和编码糖kunase多肽的DNA（RNA），以及通过重组技术产生此类多肽的方法。 还提供了筛选抗菌化合物的方法或使用糖激酶多肽。
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公开(公告)号：US6008030A
公开(公告)日：1999-12-28
申请号：US918249
申请日：1997-08-25
申请人： Michael Terence Black , John Edward Hodgson , David Justin Charles Knowles , Raymond Winfield Reichard , Richard Oakley Nicholas , Martin Karl Russel Burnham , Julie M Pratt , Martin Rosenberg , Judith M Ward , Michael Arthur Lonetto , Patrick Vernon Warren
发明人： Michael Terence Black , John Edward Hodgson , David Justin Charles Knowles , Raymond Winfield Reichard , Richard Oakley Nicholas , Martin Karl Russel Burnham , Julie M Pratt , Martin Rosenberg , Judith M Ward , Michael Arthur Lonetto , Patrick Vernon Warren
IPC分类号： G01N33/50 , A61K31/70 , A61K38/00 , A61K38/04 , A61K38/44 , A61K38/55 , A61K39/00 , A61K39/395 , A61K45/00 , A61K48/00 , A61P31/04 , A61P35/00 , A61P37/00 , A61P37/04 , A61P43/00 , C07K14/31 , C07K16/12 , C12N1/00 , C12N1/21 , C12N9/00 , C12N9/04 , C12N9/12 , C12N9/14 , C12N9/88 , C12N15/00 , C12N15/09 , C12N15/31 , C12N15/53 , C12N15/54 , C12P21/02 , C12P21/08 , C12Q1/02 , C12Q1/68 , C12R1/19 , C12R1/44 , C12R1/445 , G01N33/15 , G01N33/53 , G01N33/569 , G01N33/573 , C12N1/20 , C12P21/06
CPC分类号： C12N9/0006 , C07K14/31 , C12N9/00 , C12N9/1205 , C12N9/88 , A61K38/00 , A61K39/00 , C07K2319/00 , Y10S435/883
摘要： The invention provides sugar kinase polypeptides and DNA (RNA) encoding sugar kinase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing sugar kinase polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了糖激酶多肽和编码糖激酶多肽的DNA（RNA），以及通过重组技术产生此类多肽的方法。 还提供了利用糖激酶多肽筛选抗菌化合物的方法。
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公开(公告)号：US06248556B1
公开(公告)日：2001-06-19
申请号：US08879098
申请日：1997-06-19
申请人： Michael Terence Black , Martin Karl Russel Burnham , John Edward Hodgson , David Justin Charles Knowles , Richard O Nicholas , Julie M Pratt , Raymond Winfield Reichard , Martin Rosenberg , Judith M Ward
发明人： Michael Terence Black , Martin Karl Russel Burnham , John Edward Hodgson , David Justin Charles Knowles , Richard O Nicholas , Julie M Pratt , Raymond Winfield Reichard , Martin Rosenberg , Judith M Ward
IPC分类号： C12P2100
CPC分类号： C12N9/78 , A61K39/00 , C07K14/31 , C07K16/1275 , C12Y305/04025
摘要： The invention provides ERA polypeptides and DNA (RNA) encoding ERA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ERA polypeptide for the protection against infection, particularly bacterial infections.
摘要翻译： 本发明提供了ERA多肽和编码ERA多肽的DNA（RNA）以及通过重组技术产生此类多肽的方法。 还提供了利用ERA多肽以防止感染，特别是细菌感染的方法。
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公开(公告)号：US06465621B1
公开(公告)日：2002-10-15
申请号：US09631548
申请日：2000-08-03
申请人： Michael Terence Black , John Edward Hodgson , David Justin Charles Knowles , Raymond Winfield Reichard , Richard O Nicholas , Martin Karl Russel Burnham , Julie M Pratt , Martin Rosenberg , Judith M Ward
发明人： Michael Terence Black , John Edward Hodgson , David Justin Charles Knowles , Raymond Winfield Reichard , Richard O Nicholas , Martin Karl Russel Burnham , Julie M Pratt , Martin Rosenberg , Judith M Ward
IPC分类号： C07K1700
CPC分类号： C12N9/78 , A61K39/00 , C07K14/31 , C07K16/1275 , C12Y305/04025
摘要： The invention provides ERA polypeptides and DNA (RNA) encoding ERA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ERA polypeptide for the protection against infection, particularly bacterial infections.
摘要翻译： 本发明提供了ERA多肽和编码ERA多肽的DNA（RNA）以及通过重组技术产生此类多肽的方法。 还提供了利用ERA多肽以防止感染，特别是细菌感染的方法。
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公开(公告)号：US06228619B1
公开(公告)日：2001-05-08
申请号：US08948265
申请日：1997-10-09
申请人： Simon J Foster , Michael Terence Black , John Edward Hodgson , David Justin Charles Knowles , Raymond Winfield Reichard , Richard O Nicholas , Martin Karl Russel Burnham , Julie M Pratt , Martin Rosenberg , Judith M Ward
发明人： Simon J Foster , Michael Terence Black , John Edward Hodgson , David Justin Charles Knowles , Raymond Winfield Reichard , Richard O Nicholas , Martin Karl Russel Burnham , Julie M Pratt , Martin Rosenberg , Judith M Ward
IPC分类号： C12N1509
CPC分类号： C12Y302/01096 , A61K39/00 , A61K2039/53 , C07K14/31 , C07K16/1275 , C12N9/2402 , C12N9/78 , C12Y302/01023 , C12Y305/04025
摘要： The invention provides glucosaminidase polypeptides and DNA (RNA) encoding glucosaminidase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing glucosaminidase polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了氨基葡糖苷酶多肽和编码氨基葡糖苷酶多肽的DNA（RNA），以及通过重组技术产生这种多肽的方法。 还提供了利用氨基葡糖苷酶多肽筛选抗菌化合物的方法。
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