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    Energy-efficient lighting panel
    13.
    发明授权
    Energy-efficient lighting panel 有权
    节能照明面板

    公开(公告)号：US08845174B2

    公开(公告)日：2014-09-30

    申请号：US13215596

    申请日：2011-08-23

    Applicant: Nicholas Jackson ,  Brian Retzke

    Inventor： Nicholas Jackson ,  Brian Retzke

    IPC: F21V7/04 ,  F21V99/00

    CPC classification number: F21V99/00 ,  F21V33/006 ,  F21Y2103/00 ,  F21Y2105/00 ,  F21Y2113/00 ,  F21Y2115/10 ,  G02B6/0088 ,  G02B6/0096

    Abstract: A light-weight and energy-efficient lighting panel is constructed from a light-transmissive and light diffusive extrusion formed to have elongated hollows, which are hollow structures or volumes between two surfaces, at least one of which is transmissive and diffusive. Light projected into the hollow flows through the hollow and part of the light is emitted through the light transmissive and diffusive surfaces. Even though the light sources are located at the edges of a panel, the surface of the panel appears to be uniformly light by light sources distribute directly behind the panels rather than along the edges.

    Abstract translation: 轻质和节能的照明面板由透光和光漫射挤压构成，其形成为具有细长的中空，其是两个表面之间的中空结构或体积，其中至少一个是透射和扩散的。 投射到空心中的光流过中空，部分光通过透光和漫射表面发射。 即使光源位于面板的边缘，由于光源直接分布在面板后面，而不是沿着边缘，面板的表面看起来是均匀的。

    HIV-1 clade a consensus sequences, antigens, and transgenes
    14.
    发明授权
    HIV-1 clade a consensus sequences, antigens, and transgenes 有权
    HIV-1携带共有序列，抗原和转基因

    公开(公告)号：US08735542B2

    公开(公告)日：2014-05-27

    申请号：US13398897

    申请日：2012-02-17

    Applicant: Kalpana Gupta ,  Nicholas Jackson

    Inventor： Kalpana Gupta ,  Nicholas Jackson

    IPC: C07K1/00 ,  A61K38/00 ,  A61K38/16 ,  A61K39/00 ,  A61K39/12 ,  A61K39/21

    CPC classification number: C12Q1/703 ,  A61K39/00 ,  A61K2039/53 ,  C07K14/005 ,  C12N2710/10343 ,  C12N2740/16122 ,  C12N2740/16222 ,  C12N2740/16322

    Abstract: The present invention relates to consensus nucleotide and protein sequences for HIV-1 Clade A antigens, and to nucleotide and protein sequences for Clade A antigens from circulating HIV-1 field isolates wherein the antigen sequences are closely related to the these consensus sequences. Advantageously, the present invention relates to HIV-1 Clade A transgenes that are derived from such sequences, and that encode either HIV-1 Clade A Gag, Pol (RT and Int), and Nef (collectively “GRIN”), HIV-1 Clade A Gag, RT, and Nef (collectively “GRN”), or HIV-1 Clade A Env. The invention also relates to vectors containing such transgenes, including adenovirus vectors containing such transgenes. The invention also relates to immunogenic compositions comprising the HIV-1 Clade A antigens, nucleotide sequences, vectors, or transgenes of the invention, and to methods of generating an immune response against HIV in a subject by administering an effective amount of such immunogenic compositions.

    Abstract translation: 本发明涉及用于HIV-1进化枝A抗原的共有核苷酸和蛋白质序列，以及来自循环HIV-1场分离株的克隆A抗原的核苷酸和蛋白质序列，其中所述抗原序列与这些共有序列密切相关。 有利地，本发明涉及从这样的序列衍生的编码HIV-1分子A Gag，Pol（RT和Int）和Nef（统称为“GRIN”）的HIV-1进化枝A转基因，HIV-1 Clade A Gag，RT和Nef（统称为“GRN”）或HIV-1 Clade A Env。 本发明还涉及含有这种转基因的载体，包括含有这种转基因的腺病毒载体。 本发明还涉及包含本发明的HIV-1进化枝A抗原，核苷酸序列，载体或转基因的免疫原性组合物，以及通过施用有效量的这种免疫原性组合物在受试者中产生针对HIV的免疫应答的方法。

    HIV-1 CLADE A CONSENSUS SEQUENCES, ANTIGENS, AND TRANSGENES
    17.
    发明申请
    HIV-1 CLADE A CONSENSUS SEQUENCES, ANTIGENS, AND TRANSGENES 有权
    HIV-1 CLADE A CONSENSUS序列，抗原和转移物

    公开(公告)号：US20120219577A1

    公开(公告)日：2012-08-30

    申请号：US13398897

    申请日：2012-02-17

    Applicant: Kalpana GUPTA ,  Nicholas Jackson

    Inventor： Kalpana GUPTA ,  Nicholas Jackson

    IPC: A61K39/21 ,  C12P21/00 ,  A61P37/02 ,  C07H21/04 ,  A61K31/711

    CPC classification number: C12Q1/703 ,  A61K39/00 ,  A61K2039/53 ,  C07K14/005 ,  C12N2710/10343 ,  C12N2740/16122 ,  C12N2740/16222 ,  C12N2740/16322

    Abstract: The present invention relates to consensus nucleotide and protein sequences for HIV-1 Clade A antigens, and to nucleotide and protein sequences for Clade A antigens from circulating HIV-1 field isolates wherein the antigen sequences are closely related to the these consensus sequences. Advantageously, the present invention relates to HIV-1 Clade A transgenes that are derived from such sequences, and that encode either HIV-1 Clade A Gag, Pol (RT and Int), and Nef (collectively “GRIN”), HIV-1 Clade A Gag, RT, and Nef (collectively “GRN”), or HIV-1 Clade A Env. The invention also relates to vectors containing such transgenes, including adenovirus vectors containing such transgenes. The invention also relates to immunogenic compositions comprising the HIV-1 Clade A antigens, nucleotide sequences, vectors, or transgenes of the invention, and to methods of generating an immune response against HIV in a subject by administering an effective amount of such immunogenic compositions.

    Abstract translation: 本发明涉及用于HIV-1进化枝A抗原的共有核苷酸和蛋白质序列，以及来自循环HIV-1场分离株的克隆A抗原的核苷酸和蛋白质序列，其中所述抗原序列与这些共有序列密切相关。 有利地，本发明涉及从这样的序列衍生的编码HIV-1分子A Gag，Pol（RT和Int）和Nef（统称为“GRIN”）的HIV-1进化枝A转基因，HIV-1 Clade A Gag，RT和Nef（统称为“GRN”）或HIV-1 Clade A Env。 本发明还涉及含有这种转基因的载体，包括含有这种转基因的腺病毒载体。 本发明还涉及包含本发明的HIV-1进化枝A抗原，核苷酸序列，载体或转基因的免疫原性组合物，以及通过施用有效量的这种免疫原性组合物在受试者中产生针对HIV的免疫应答的方法。

    Fluid Filtration System and Method of Filtering Fluid
    18.
    发明申请
    Fluid Filtration System and Method of Filtering Fluid 审中-公开
    流体过滤系统和过滤流体的方法

    公开(公告)号：US20080023381A1

    公开(公告)日：2008-01-31

    申请号：US10579350

    申请日：2004-11-15

    Applicant: Nicholas Jackson ,  Andrew Clark ,  Colin French

    Inventor： Nicholas Jackson ,  Andrew Clark ,  Colin French

    IPC: B01D29/00 ,  B01D29/15 ,  B01D29/68

    CPC classification number: A01K63/045 ,  B01D29/114 ,  B01D29/682

    Abstract: The present application relates to a filtration system (1) having at least one flexible filter (9) and cleaning apparatus (25) for projecting a flow of fluid onto the at least one flexible filter. The fluid to be filtered passes through the at least cone flexible filter (9) and causes the at least one flexible filter (9) to be deflected in a first direction. The flow of fluid projected onto the at least one flexible filter (9) from the cleaning apparatus (25) causes the at least one flexible filter (9) to be deflected in a second direction. The first and second directions are substantially opposite to each other. The present invention further relates to a filtration system (1) for filtering particulates from a liquid. The filtration system has a sealed vessel (2) suitable for supporting a pressure less than atmospheric pressure. A filter (9) is provided for filtering particulates from the liquid. The application also relates to a method of filtering fluid.

    Abstract translation: 本申请涉及一种具有至少一个柔性过滤器（9）和用于将流体流投射到至少一个柔性过滤器上的清洁设备（25）的过滤系统（1）。 待过滤的流体通过至少锥形柔性过滤器（9），并使至少一个柔性过滤器（9）沿第一方向偏转。 从清洁装置（25）突出到至少一个柔性过滤器（9）上的流体流使至少一个柔性过滤器（9）沿第二方向偏转。 第一和第二方向基本上彼此相反。 本发明还涉及一种用于从液体中过滤微粒的过滤系统（1）。 过滤系统具有适于支撑低于大气压力的压力的密封容器（2）。 提供了一种用于从液体中过滤微粒的过滤器（9）。 本申请还涉及过滤流体的方法。

    Dynamic Light Effect Projecting Device
    19.
    发明申请
    Dynamic Light Effect Projecting Device 审中-公开
    动态光效投射装置

    公开(公告)号：US20140254173A1

    公开(公告)日：2014-09-11

    申请号：US13784988

    申请日：2013-03-05

    Applicant: Nicholas Jackson

    Inventor： Nicholas Jackson

    IPC: F21V14/00

    CPC classification number: F21V14/08 ,  F21S6/002

    Abstract: Light projected through a plurality of nested housings each containing elongated light transmissive openings that are intersecting along their lengths only allows the projected light to exit the device at the points where the light transmissive openings intersect. When relative rotational motion is set forth between the nested housings the intersecting points move with respect to the design of the elongated light transmissive openings and also by which housing(s) are rotated and by the speed of rotation. This allows for radial movement, axial movement and any combination of radial and axial movement of projected light points when viewed in an installation environment.

    Abstract translation: 通过多个嵌套壳体投影的光，每个嵌套的外壳各自包含沿其长度相交的细长的光透射开口，仅允许投影光在透光开口相交的点处离开设备。 当在嵌套壳体之间设置相对旋转运动时，相交点相对于细长光透射开口的设计以及壳体旋转和旋转速度移动。 这允许在安装环境中观察时的径向运动，轴向运动和投影光点的径向和轴向移动的任何组合。

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