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公开(公告)号:US20120315673A1
公开(公告)日:2012-12-13
申请号:US13518849
申请日:2010-12-18
申请人: Wolfgang Aehle , Juergen Eck , Karsten Harms , Michael Klingeberg , Stefan Pelzer , Wolfgang Wach
发明人: Wolfgang Aehle , Juergen Eck , Karsten Harms , Michael Klingeberg , Stefan Pelzer , Wolfgang Wach
摘要: For the biotechnological production of isomaltulose and compositions containing isomaltulose from saccharose the invention provides improved means, particularly a sucrose mutase with improved product specificity as well as microbial cells containing the improved sucrose mutase.
摘要翻译: 对于异麦芽酮糖的生物技术生产和含有来自蔗糖的异麦芽酮糖的组合物,本发明提供了改进的方法,特别是具有改进的产物特异性的蔗糖变位酶以及含有改进的蔗糖变位酶的微生物细胞。
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公开(公告)号:US20110281313A1
公开(公告)日:2011-11-17
申请号:US13140398
申请日:2009-12-15
申请人: Wolfgang Wach , Karsten Harms , Michael Klingeberg , Peter Duerre , Niklas Nold , Bettina Schiel
发明人: Wolfgang Wach , Karsten Harms , Michael Klingeberg , Peter Duerre , Niklas Nold , Bettina Schiel
CPC分类号: C12P7/16 , C12N15/1137 , C12N2310/11 , C12N2310/14 , C12P7/40 , C12P7/52 , C12P7/54 , Y02E50/10
摘要: The invention relates to a method and means for the bioengineered fermentative production of solvents, in particular of butanol, acetone and ethanol, and of short-chained carboxylic acids such as acetic acid and butyric acid, in particular in host cells of the species Clostridium. The invention provides new methods and means for regulating the expression of the enzyme activities involved in acid production and or solvent production of the host cell.
摘要翻译: 本发明涉及用于生物工程化发酵生产溶剂,特别是丁醇,丙酮和乙醇以及短链羧酸如乙酸和丁酸的方法和装置,特别是在梭菌属的宿主细胞中。 本发明提供调节宿主细胞的酸生产和/或溶剂生产中涉及的酶活性表达的新方法和方法。
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公开(公告)号:US06414138B1
公开(公告)日:2002-07-02
申请号:US09018359
申请日:1998-02-04
申请人: Hanspeter Degelmann , Michael Gander , Jörg Kowalczyk , Markwart Kunz , Mohammad Munir , Matthias Schüttenhelm , Wolfgang Wach
发明人: Hanspeter Degelmann , Michael Gander , Jörg Kowalczyk , Markwart Kunz , Mohammad Munir , Matthias Schüttenhelm , Wolfgang Wach
IPC分类号: C07H100
CPC分类号: C07H3/04
摘要: The invention relates to a process for producing mixtures selectively enriched with either 1,1-GPM and 1,6-GPS from hydrogenated isomaltulose. The process involves dissolving hydrogenated isomaltulose at an elevated temperature, and subjecting the resulting solution to one or more cooling steps, wherein each cooling step utilizes a predetermined cooling rate over a predetermined temperature range.
摘要翻译: 本发明涉及一种从氢化异麦芽酮糖制备选自富含1,1-GPM和1,6-GPS的混合物的方法。 该方法包括在升高的温度下溶解氢化异麦芽酮糖,并对所得溶液进行一个或多个冷却步骤,其中每个冷却步骤在预定温度范围内利用预定的冷却速率。
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公开(公告)号:US4534008A
公开(公告)日:1985-08-06
申请号:US486311
申请日:1983-04-19
IPC分类号: G01R31/3185 , H03K19/177 , H03K19/08
CPC分类号: H03K19/1772 , G01R31/318516
摘要: Given a programmable logic array, all product terms of the product matrix are applied to a prescribable potential by way of a first control signal so that the following sum matrix is no longer influenced by the input variables. Additional transfer elements are controllable by a second control signal, the additional transfer elements being assigned to additional terminal connecting points between the sum terms of the sum matrix. Depending upon the execution and employment of the logic array, the two control signals can be independent of one another, identical to one another, or inverted relative to one another.
摘要翻译: 给定可编程逻辑阵列,通过第一控制信号将产品矩阵的所有乘积项施加到可规定的电位,使得以下和矩阵不再受输入变量的影响。 附加传送元件可由第二控制信号控制,附加传送元件被分配给和矩阵的和项之间的附加终端连接点。 根据逻辑阵列的执行和使用,两个控制信号可以彼此独立,彼此相同,或相对于彼此相反。
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公开(公告)号:US10246729B2
公开(公告)日:2019-04-02
申请号:US13695258
申请日:2011-05-12
申请人: Jan Van Loo , Wolfgang Wach
发明人: Jan Van Loo , Wolfgang Wach
IPC分类号: A23L29/30 , C12P13/04 , C07C227/40 , C12P13/00 , C12P19/00 , C12P19/18 , C13K13/00 , A23K20/163 , A23L33/22
摘要: A process for the recovery of betaine from a molasses comprises a conversion step, in which the molasses is subjected to the action of an enzyme having endo-inulinase activity and/or fructosyltransferase activity, to form a fructan-containing molasses (fructan-molasses); a separation step, in which the fructan-molasses is subjected to a chromatographic separation, thereby obtaining a betaine-containing fraction.
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公开(公告)号:US08679799B2
公开(公告)日:2014-03-25
申请号:US13140398
申请日:2009-12-15
申请人: Wolfgang Wach , Karsten Harms , Michael Klingeberg , Peter Duerre , Niklas Nold , Bettina Schiel
发明人: Wolfgang Wach , Karsten Harms , Michael Klingeberg , Peter Duerre , Niklas Nold , Bettina Schiel
CPC分类号: C12P7/16 , C12N15/1137 , C12N2310/11 , C12N2310/14 , C12P7/40 , C12P7/52 , C12P7/54 , Y02E50/10
摘要: The invention relates to a method and means for the bioengineered fermentative production of solvents, in particular of butanol, acetone and ethanol, and of short-chained carboxylic acids such as acetic acid and butyric acid, in particular in host cells of the species Clostridium. The invention provides new methods and means for regulating the expression of the enzyme activities involved in acid production and or solvent production of the host cell.
摘要翻译: 本发明涉及用于生物工程化发酵生产溶剂,特别是丁醇,丙酮和乙醇以及短链羧酸如乙酸和丁酸的方法和装置,特别是在梭菌属的宿主细胞中。 本发明提供调节宿主细胞的酸生产和/或溶剂生产中涉及的酶活性表达的新方法和方法。
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17.
公开(公告)号:US20080213341A1
公开(公告)日:2008-09-04
申请号:US12088396
申请日:2006-09-28
申请人: Alireza Haji Begli , Michael Klingeberg , Jorg Kowalczyk , Gunhild Kozianowski , Stephan Theis , Wolfgang Wach
发明人: Alireza Haji Begli , Michael Klingeberg , Jorg Kowalczyk , Gunhild Kozianowski , Stephan Theis , Wolfgang Wach
IPC分类号: A61K9/00 , A61K31/19 , A61K31/047 , A61P1/00 , A61K9/10
CPC分类号: A61K31/70
摘要: The invention relates to butyric acid esters or butyrate esters of carbohydrates and carbohydrate polyols and their use as a butyrate carrier and butyrate source for the gastrointestinal tract, in particular for the prevention and treatment of diseases of the gastrointestinal tract, especially of the large intestine.
摘要翻译: 本发明涉及碳水化合物和碳水化合物多元醇的丁酸酯或丁酸酯及其作为胃肠道的丁酸酯载体和丁酸酯源的用途,特别是用于预防和治疗胃肠道,特别是大肠的疾病。
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公开(公告)号:US5578339A
公开(公告)日:1996-11-26
申请号:US238692
申请日:1994-05-05
申请人: Markwart Kunz , Hanspeter Degelmann , Wolfgang Wach , Mohammad Munir , Jorg Kowalczyk , Manfred Vogel
发明人: Markwart Kunz , Hanspeter Degelmann , Wolfgang Wach , Mohammad Munir , Jorg Kowalczyk , Manfred Vogel
IPC分类号: A23L27/30 , C12P19/02 , C12P19/12 , C12P19/24 , C12R1/38 , A23L1/236 , C12P19/18 , C12P41/00
CPC分类号: C12P19/24 , A23L27/34 , C12P19/12 , Y10S435/847 , Y10S435/874 , Y10S435/88
摘要: A process for the preparation of a sweetener, in which sucrose is converted enzymatically into a saccharide mixture which is called "isomerized sucrose" and has a disaccharide content of more than 85% by weight, then non-isomerized remaining sucrose is removed from the latter by enzymatic and/or H.sup.+ ion-catalyzed cleavage, and this product is catalytically hydrogenated. Preferably either before or after the catalytic hydrogenation, the resulting mixture is subjected to a chromatographic separation. The sweeteners prepared by this process contain either a mixture of 10 to 50% by weight of 6-O-.alpha.-D-glucopyranosyl-D-sorbitol; 2 to 20% by weight of 1-O-.alpha.-D-glucopyranosyl-D-sorbitol; and 30 to 70% by weight of 1-O-.alpha.-D-glucopyranosyl-D-mannitol or of 5 to 10% by weight of 6-O-.alpha.-D-glucopyranosyl-D-sorbitol; 30 to 40% by weight of 1-O-.alpha.-D-glucopyranosyl-D-sorbitol; and 45 to 60% by weight of 1-O-.alpha.-D-glucopyranosyl-D-mannitol.
摘要翻译: 一种制备甜味剂的方法,其中将蔗糖酶促转化为称为“异构化蔗糖”并且二糖含量大于85重量%的糖混合物,然后从其中除去未异构化的剩余蔗糖 通过酶促和/或H +离子催化裂解,并且该产物被催化氢化。 优选在催化氢化之前或之后,将所得混合物进行色谱分离。 通过该方法制备的甜味剂包含10至50重量%的6-O-α-D-吡喃葡萄糖基-D-山梨糖醇的混合物; 2〜20重量%的1-O-α-D-吡喃葡萄糖基-D-山梨糖醇; 和30至70重量%的1-O-α-D-吡喃葡萄糖基-D-甘露醇或5至10重量%的6-O-α-D-吡喃葡萄糖基-D-山梨糖醇; 30至40重量%的1-O-α-D-吡喃葡萄糖基-D-山梨糖醇; 和45至60重量%的1-O-α-D-吡喃葡萄糖基-D-甘露糖醇。
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