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    METHOD OF DETECTING A SUBSTANCE
    15.
    发明申请
    METHOD OF DETECTING A SUBSTANCE 有权

    公开(公告)号：US20220003760A1

    公开(公告)日：2022-01-06

    申请号：US17172078

    申请日：2021-02-10

    Applicant: Purdue Research Foundation

    Inventor： Jeffrey Frederick Rhoads ,  Eric A. Nauman ,  Mackenzie Tweardy ,  Michael Wadas ,  Allison Kelly Murray ,  George Tsu-Chih Chiu ,  Nikhil Bajaj

    IPC: G01N33/543 ,  G01N33/547 ,  C07K16/18

    Abstract: A method of detecting a substance, wherein the method includes functionalizing a plurality of sensors, wherein the functionalizing the plurality of sensors comprises depositing a first material using a piezoelectrically actuated pipette system, wherein the first material includes a polymer, a receptor, and a solvent, wherein the solvent comprises dimethylformamide. The method further includes evaporating a solution of the first material, wherein a residue after the evaporation comprises a functionalized chemical. Additionally, the method includes introducing a control material to a first set of sensors of the plurality of sensors using the piezoelectrically actuated pipette system. Further, the method includes introducing a test material to a second set of sensors of the plurality of sensors using the piezoelectrically actuated pipette system, wherein the test material comprises an analyte. Moreover the method includes determining a difference between a first resonant frequency shift in the first set of sensors of the plurality of sensors and a second resonant frequency shift in the second set of sensors of the plurality of sensors.

    Nonlinear mass sensors based on electronic feedback
    19.
    发明授权
    Nonlinear mass sensors based on electronic feedback 有权

    公开(公告)号：US11060998B2

    公开(公告)日：2021-07-13

    申请号：US16333273

    申请日：2018-12-04

    Applicant: Purdue Research Foundation

    Inventor： Jeffrey Frederick Rhoads ,  George Tsu-Chih Chiu ,  Nikhil Bajaj

    IPC: G01N29/12 ,  G01N29/036

    Abstract: This present disclosure relates to sensors capable of sensing mass, stiffness, and chemical or biological substances. More specifically, this disclosure provides the design and implementation of a piecewise-linear resonator realized via diode- and integrated circuit-based feedback electronics and a quartz crystal resonator. The proposed system is fabricated and characterized, and the creation and selective placement of the bifurcation points of the overall electromechanical system is demonstrated by tuning the circuit gains. The demonstrated circuit operates around at least 1 MHz.

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