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公开(公告)号:US6054479A
公开(公告)日:2000-04-25
申请号:US340765
申请日:1999-06-28
申请人: Ruey J. Yu , Eugene J. Van Scott
发明人: Ruey J. Yu , Eugene J. Van Scott
IPC分类号: A23L3/3481 , A23L3/349 , A23L3/3499 , A23L3/3508 , A23L3/3517 , A61K8/34 , A61K8/368 , A61K8/37 , A61K8/40 , A61K8/41 , A61K8/43 , A61K8/49 , A61K8/92 , A61K31/185 , A61K31/215 , A61K31/22 , A61K31/222 , A61K31/235 , A61K31/34 , A61K31/415 , A61K31/43 , A61K31/44 , A61K31/495 , A61K31/535 , A61K38/12 , A61Q1/12 , A61Q3/00 , A61Q5/00 , A61Q11/00 , A61Q15/00 , A61Q17/00 , A61Q19/00
CPC分类号: A61Q17/005 , A23L3/3481 , A23L3/349 , A23L3/3499 , A23L3/3508 , A23L3/3517 , A61K31/215 , A61K31/22 , A61K31/222 , A61K31/235 , A61K31/34 , A61K31/415 , A61K31/43 , A61K31/44 , A61K31/495 , A61K31/535 , A61K31/70 , A61K38/12 , A61K8/34 , A61K8/368 , A61K8/37 , A61K8/40 , A61K8/41 , A61K8/43 , A61K8/49 , A61K8/4926 , A61K8/494 , A61K8/4973 , A61K8/92 , A61Q15/00 , A61K2800/524 , A61Q1/12 , A61Q11/00 , A61Q19/00 , A61Q3/00 , A61Q5/00
摘要: Therapeutic treatment as well as prophylactic measures are provided by topical application of compositions containing an aryl 2-acetoxyethanoic acid to eradicate or prevent the development of axillary foul odor, foot malodor and other body odors, e.g. scalp, and skin, nail and follicular infections caused by microorganisms. The compositions are antimicrobial against several organisms that infect the skin and are specifically effective against P. acnes. The compositions are therapeutically effective against folliculitis and perifolliculitis and are useful for other skin lesions, nail and mucosal infections such as impetigo, seborrheic dermatitis, erythrasma and trichomycosis axillaris, associated with or caused by microorganisms. The therapeutic effect of the composition may be synergized or amplified by incorporating a cosmetic or dermatologic agent into the formulation for topical treatment of cosmetic and dermatologic indications. The compositions are also useful as preservatives in food products, cosmetic and pharmaceutical formulations, and industrial preparations.
摘要翻译: 通过局部施用含有2-乙酰氧基乙酸芳基酯的组合物来提供治疗性治疗以及预防措施,以消除或预防腋臭,脚臭和其它身体气味的发展。 头皮和皮肤,微生物引起的指甲和滤泡感染。 所述组合物对几种感染皮肤的生物具有抗微生物性,并且对抗痤疮丙酸杆菌特别有效。 所述组合物对于毛囊炎和血管周围炎是治疗有效的,并且可用于与微生物相关或由微生物引起的其它皮肤损伤,指甲和粘膜感染如脓疱疮,脂溢性皮炎,红斑狼疮和毛状癣菌。 组合物的治疗效果可以通过将化妆品或皮肤病剂掺入到用于局部治疗化妆品和皮肤病适应症的制剂中来协同或扩增。 该组合物还可用作食品,化妆品和药物制剂以及工业制剂中的防腐剂。
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12.Antiodor, antimicrobial and preservative compositions and methods of using same 失效
标题翻译: 抗氧化剂,抗微生物剂和防腐剂组合物及其使用方法公开(公告)号:US5958975A
公开(公告)日:1999-09-28
申请号:US164005
申请日:1998-09-30
申请人: Ruey J. Yu , Eugene J. Van Scott
发明人: Ruey J. Yu , Eugene J. Van Scott
IPC分类号: A61L9/01 , A01N37/36 , A23L3/3481 , A23L3/349 , A23L3/3499 , A23L3/3508 , A23L3/3517 , A61K8/00 , A61K8/30 , A61K8/33 , A61K8/34 , A61K8/36 , A61K8/368 , A61K8/37 , A61K8/40 , A61K8/41 , A61K8/43 , A61K8/49 , A61K8/64 , A61K8/92 , A61K31/047 , A61K31/185 , A61K31/19 , A61K31/215 , A61K31/22 , A61K31/222 , A61K31/235 , A61K31/34 , A61K31/415 , A61K31/43 , A61K31/44 , A61K31/495 , A61K31/505 , A61K31/535 , A61K31/60 , A61K38/12 , A61P1/02 , A61P17/00 , A61P31/04 , A61P31/12 , A61P43/00 , A61Q1/12 , A61Q3/00 , A61Q5/00 , A61Q11/00 , A61Q15/00 , A61Q17/00 , A61Q19/00
CPC分类号: A61Q15/00 , A23L3/3481 , A23L3/349 , A23L3/3499 , A23L3/3508 , A23L3/3517 , A61K31/215 , A61K31/22 , A61K31/222 , A61K31/235 , A61K31/34 , A61K31/415 , A61K31/43 , A61K31/44 , A61K31/495 , A61K31/535 , A61K31/60 , A61K31/70 , A61K38/12 , A61K8/34 , A61K8/368 , A61K8/37 , A61K8/40 , A61K8/41 , A61K8/43 , A61K8/49 , A61K8/4926 , A61K8/494 , A61K8/4973 , A61K8/92 , A61Q11/00 , A61Q17/005 , A61Q19/00 , A61Q3/00 , A61K2800/524 , A61Q1/12 , A61Q17/00 , A61Q19/008 , A61Q5/00 , A61Q5/006 , Y10S514/844 , Y10S514/847 , Y10S514/859 , Y10S514/863 , Y10S514/873
摘要: Therapeutic treatment as well as prophylactic measures are provided by topical application of compositions containing an aryl 2-acetoxyethanoic acid to eradicate or prevent the development of axillary foul odor, foot malodor and other body odors, e.g. scalp, and skin, nail and follicular infections caused by microorganisms. The compositions are antimicrobial against several organisms that infect the skin and are specifically effective against P. acnes. The compositions are therapeutically effective against folliculitis and perifolliculitis and are useful for other skin lesions, nail and mucosal infections such as impetigo, seborrheic dermatitis, erythrasma and trichomycosis axillaris, associated with or caused by microorganisms. The therapeutic effect of the composition may be synergized or amplified by incorporating a cosmetic or dermatologic agent into the formulation for topical treatment of cosmetic and dermatologic indications. The compositions are also useful as preservatives in food products, cosmetic and pharmaceutical formulations, and industrial preparations.
摘要翻译: 通过局部施用含有2-乙酰氧基乙酸芳基酯的组合物来提供治疗性治疗以及预防措施,以消除或预防腋臭,脚臭和其它身体气味的发展。 头皮和皮肤,微生物引起的指甲和滤泡感染。 所述组合物对几种感染皮肤的生物具有抗微生物性,并且对抗痤疮丙酸杆菌特别有效。 所述组合物对于毛囊炎和血管周围炎是治疗有效的,并且可用于与微生物相关或由微生物引起的其它皮肤病变,指甲和粘膜感染如脓疱疮,脂溢性皮炎,红斑狼疮和毛状癣菌。 组合物的治疗效果可以通过将化妆品或皮肤病剂掺入到用于局部治疗化妆品和皮肤病适应症的制剂中来协同或扩增。 该组合物还可用作食品,化妆品和药物制剂以及工业制剂中的防腐剂。
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公开(公告)号:US5684044A
公开(公告)日:1997-11-04
申请号:US472315
申请日:1995-06-07
申请人: Ruey J. Yu , Eugene J. Van Scott
发明人: Ruey J. Yu , Eugene J. Van Scott
IPC分类号: A61K8/26 , A61K8/27 , A61K8/34 , A61K8/362 , A61K8/365 , A61K8/37 , A61K8/38 , A61K8/41 , A61K8/42 , A61K8/43 , A61K8/44 , A61K8/49 , A61K8/55 , A61K8/58 , A61K8/60 , A61K8/63 , A61K8/64 , A61K8/67 , A61K8/68 , A61K8/81 , A61K8/85 , A61K31/19 , A61K31/191 , A61K31/192 , A61K31/194 , A61K31/195 , A61K31/20 , A61K31/202 , A61K31/365 , A61K31/366 , A61K31/40 , A61K31/405 , A61K31/415 , A61K31/445 , A61K31/66 , A61K31/70 , A61K31/715 , A61K45/06 , A61K47/12 , A61K47/18 , A61K47/24 , A61K47/26 , A61Q5/00 , A61Q5/02 , A61Q7/00 , A61Q15/00 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/08 , A61Q19/10 , B01J19/00 , C02F1/56 , A61K7/48
CPC分类号: A61K9/0014 , A61K31/19 , A61K31/191 , A61K31/192 , A61K31/194 , A61K31/195 , A61K31/20 , A61K31/202 , A61K31/365 , A61K31/366 , A61K31/40 , A61K31/405 , A61K31/415 , A61K31/445 , A61K31/66 , A61K31/70 , A61K31/7012 , A61K31/7048 , A61K31/715 , A61K45/06 , A61K47/12 , A61K47/183 , A61K47/24 , A61K47/26 , A61K8/26 , A61K8/27 , A61K8/347 , A61K8/362 , A61K8/365 , A61K8/37 , A61K8/375 , A61K8/38 , A61K8/41 , A61K8/416 , A61K8/42 , A61K8/43 , A61K8/44 , A61K8/4913 , A61K8/494 , A61K8/4953 , A61K8/4973 , A61K8/55 , A61K8/553 , A61K8/585 , A61K8/60 , A61K8/63 , A61K8/64 , A61K8/671 , A61K8/675 , A61K8/678 , A61K8/68 , A61K8/8152 , A61K8/85 , A61Q15/00 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/004 , A61Q19/007 , A61Q19/008 , A61Q19/02 , A61Q19/08 , A61Q19/10 , A61Q5/00 , A61Q5/006 , A61Q5/02 , A61Q7/00 , B01J19/0013 , C02F1/56 , B01J2219/00063 , B01J2219/00135 , B01J2219/00157 , Y10S514/844 , Y10S514/847 , Y10S514/873 , Y10S514/941 , Y10S514/944
摘要: Methods for improved topical delivery of lactic acid comprising forming a topically acceptable composition by admixing lactic acid and an amphoteric or pseudoamphoteric agent, and applying said topically acceptable composition to the skin.
摘要翻译: 用于改进乳酸局部递送的方法,包括通过混合乳酸和两性或假性交联剂形成局部可接受的组合物,以及将所述局部可接受的组合物施用于皮肤。
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公开(公告)号:US5650440A
公开(公告)日:1997-07-22
申请号:US471513
申请日:1995-06-06
申请人: Ruey J. Yu , Eugene J. Van Scott
发明人: Ruey J. Yu , Eugene J. Van Scott
IPC分类号: A61K8/26 , A61K8/27 , A61K8/34 , A61K8/362 , A61K8/365 , A61K8/37 , A61K8/38 , A61K8/41 , A61K8/42 , A61K8/43 , A61K8/44 , A61K8/49 , A61K8/55 , A61K8/58 , A61K8/60 , A61K8/63 , A61K8/64 , A61K8/67 , A61K8/68 , A61K8/81 , A61K8/85 , A61K31/19 , A61K31/191 , A61K31/192 , A61K31/194 , A61K31/195 , A61K31/20 , A61K31/202 , A61K31/365 , A61K31/366 , A61K31/40 , A61K31/405 , A61K31/415 , A61K31/445 , A61K31/66 , A61K31/70 , A61K31/715 , A61K45/06 , A61K47/12 , A61K47/18 , A61K47/24 , A61K47/26 , A61Q5/00 , A61Q5/02 , A61Q7/00 , A61Q15/00 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/08 , A61Q19/10 , B01J19/00 , C02F1/56 , A61K7/48
CPC分类号: A61K9/0014 , A61K31/19 , A61K31/191 , A61K31/192 , A61K31/194 , A61K31/195 , A61K31/20 , A61K31/202 , A61K31/365 , A61K31/366 , A61K31/40 , A61K31/405 , A61K31/415 , A61K31/445 , A61K31/66 , A61K31/70 , A61K31/7012 , A61K31/7048 , A61K31/715 , A61K45/06 , A61K47/12 , A61K47/183 , A61K47/24 , A61K47/26 , A61K8/26 , A61K8/27 , A61K8/347 , A61K8/362 , A61K8/365 , A61K8/37 , A61K8/375 , A61K8/38 , A61K8/41 , A61K8/416 , A61K8/42 , A61K8/43 , A61K8/44 , A61K8/4913 , A61K8/494 , A61K8/4953 , A61K8/4973 , A61K8/55 , A61K8/553 , A61K8/585 , A61K8/60 , A61K8/63 , A61K8/64 , A61K8/671 , A61K8/675 , A61K8/678 , A61K8/68 , A61K8/8152 , A61K8/85 , A61Q15/00 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/004 , A61Q19/007 , A61Q19/008 , A61Q19/02 , A61Q19/08 , A61Q19/10 , A61Q5/00 , A61Q5/006 , A61Q5/02 , A61Q7/00 , B01J19/0013 , C02F1/56 , B01J2219/00063 , B01J2219/00135 , B01J2219/00157 , Y10S514/844 , Y10S514/847 , Y10S514/873 , Y10S514/941 , Y10S514/944
摘要: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin citramalic acid.
摘要翻译: 用于明显减少皮肤皱纹和逆转人类面部皮肤老化的影响的方法,包括局部施用于皱纹和/或影响的面部皮肤柠檬酸。
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公开(公告)号:US5648395A
公开(公告)日:1997-07-15
申请号:US466739
申请日:1995-06-06
申请人: Ruey J. Yu , Eugene J. Van Scott
发明人: Ruey J. Yu , Eugene J. Van Scott
IPC分类号: A61K8/26 , A61K8/27 , A61K8/34 , A61K8/362 , A61K8/365 , A61K8/37 , A61K8/38 , A61K8/41 , A61K8/42 , A61K8/43 , A61K8/44 , A61K8/49 , A61K8/55 , A61K8/58 , A61K8/60 , A61K8/63 , A61K8/64 , A61K8/67 , A61K8/68 , A61K8/81 , A61K8/85 , A61K31/19 , A61K31/191 , A61K31/192 , A61K31/194 , A61K31/195 , A61K31/20 , A61K31/202 , A61K31/365 , A61K31/366 , A61K31/40 , A61K31/405 , A61K31/415 , A61K31/445 , A61K31/66 , A61K31/70 , A61K31/715 , A61K45/06 , A61K47/12 , A61K47/18 , A61K47/24 , A61K47/26 , A61Q5/00 , A61Q5/02 , A61Q7/00 , A61Q15/00 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/08 , A61Q19/10 , B01J19/00 , C02F1/56 , A61K7/48
CPC分类号: A61K9/0014 , A61K31/19 , A61K31/191 , A61K31/192 , A61K31/194 , A61K31/195 , A61K31/20 , A61K31/202 , A61K31/365 , A61K31/366 , A61K31/40 , A61K31/405 , A61K31/415 , A61K31/445 , A61K31/66 , A61K31/70 , A61K31/7012 , A61K31/7048 , A61K31/715 , A61K45/06 , A61K47/12 , A61K47/183 , A61K47/24 , A61K47/26 , A61K8/26 , A61K8/27 , A61K8/347 , A61K8/362 , A61K8/365 , A61K8/37 , A61K8/375 , A61K8/38 , A61K8/41 , A61K8/416 , A61K8/42 , A61K8/43 , A61K8/44 , A61K8/4913 , A61K8/494 , A61K8/4953 , A61K8/4973 , A61K8/55 , A61K8/553 , A61K8/585 , A61K8/60 , A61K8/63 , A61K8/64 , A61K8/671 , A61K8/675 , A61K8/678 , A61K8/68 , A61K8/8152 , A61K8/85 , A61Q15/00 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/004 , A61Q19/007 , A61Q19/008 , A61Q19/02 , A61Q19/08 , A61Q19/10 , A61Q5/00 , A61Q5/006 , A61Q5/02 , A61Q7/00 , B01J19/0013 , C02F1/56 , B01J2219/00063 , B01J2219/00135 , B01J2219/00157 , Y10S514/844 , Y10S514/847 , Y10S514/873 , Y10S514/941 , Y10S514/944
摘要: Preventive as well as therapeutic treatment to alleviate cosmetic conditions and symptoms of dermatologic disorders with amphoteric compositions containing alpha hydroxyacids, alpha ketoacids, related compounds or polymeric forms of hydroxyacids is disclosed. The cosmetic conditions and the dermatologic disorders in which the amphoteric compositions and the polymeric compounds may be useful include dry skin, dandruff, acne, keratoses, psoriasis, eczema, pruritus, age spots, lentigines, melasmas, wrinkles, warts, blemished skin, hyperpigmented skin, kyperkeratotic skin, inflammatory dermatoses, skin changes associated with aging, and skin requiring cleansers.
摘要翻译: 公开了用含有α-羟基酸,α-酮酸,相关化合物或聚合形式的羟基酸的两性组合物来减轻化妆品状况和皮肤病症状的预防和治疗。 两性组合物和聚合物可能有用的美容条件和皮肤病学障碍包括干性皮肤,头皮屑,痤疮,角化病,牛皮癣,湿疹,瘙痒,老年斑,斑点,黑斑病,皱纹,疣,瑕疵皮肤,色素沉着 皮肤,皮肤过敏皮肤,炎性皮肤病,与老化有关的皮肤变化,以及需要清洁剂的皮肤。
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公开(公告)号:US5643962A
公开(公告)日:1997-07-01
申请号:US466740
申请日:1995-06-06
申请人: Ruey J. Yu , Eugene J. Van Scott
发明人: Ruey J. Yu , Eugene J. Van Scott
IPC分类号: A61K8/26 , A61K8/27 , A61K8/34 , A61K8/362 , A61K8/365 , A61K8/37 , A61K8/38 , A61K8/41 , A61K8/42 , A61K8/43 , A61K8/44 , A61K8/49 , A61K8/55 , A61K8/58 , A61K8/60 , A61K8/63 , A61K8/64 , A61K8/67 , A61K8/68 , A61K8/81 , A61K8/85 , A61K31/19 , A61K31/191 , A61K31/192 , A61K31/194 , A61K31/195 , A61K31/20 , A61K31/202 , A61K31/365 , A61K31/366 , A61K31/40 , A61K31/405 , A61K31/415 , A61K31/445 , A61K31/66 , A61K31/70 , A61K31/715 , A61K45/06 , A61K47/12 , A61K47/18 , A61K47/24 , A61K47/26 , A61Q5/00 , A61Q5/02 , A61Q7/00 , A61Q15/00 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/08 , A61Q19/10 , B01J19/00 , C02F1/56 , A61K7/48
CPC分类号: A61K9/0014 , A61K31/19 , A61K31/191 , A61K31/192 , A61K31/194 , A61K31/195 , A61K31/20 , A61K31/202 , A61K31/365 , A61K31/366 , A61K31/40 , A61K31/405 , A61K31/415 , A61K31/445 , A61K31/66 , A61K31/70 , A61K31/7012 , A61K31/7048 , A61K31/715 , A61K45/06 , A61K47/12 , A61K47/183 , A61K47/24 , A61K47/26 , A61K8/26 , A61K8/27 , A61K8/347 , A61K8/362 , A61K8/365 , A61K8/37 , A61K8/375 , A61K8/38 , A61K8/41 , A61K8/416 , A61K8/42 , A61K8/43 , A61K8/44 , A61K8/4913 , A61K8/494 , A61K8/4953 , A61K8/4973 , A61K8/55 , A61K8/553 , A61K8/585 , A61K8/60 , A61K8/63 , A61K8/64 , A61K8/671 , A61K8/675 , A61K8/678 , A61K8/68 , A61K8/8152 , A61K8/85 , A61Q15/00 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/004 , A61Q19/007 , A61Q19/008 , A61Q19/02 , A61Q19/08 , A61Q19/10 , A61Q5/00 , A61Q5/006 , A61Q5/02 , A61Q7/00 , B01J19/0013 , C02F1/56 , B01J2219/00063 , B01J2219/00135 , B01J2219/00157 , Y10S514/844 , Y10S514/847 , Y10S514/873 , Y10S514/941 , Y10S514/944
摘要: Preventive as well as therapeutic treatment to alleviate cosmetic conditions and symptoms of dermatologic disorders with amphoteric compositions containing alpha hydroxyacids, alpha ketoacids, related compounds or polymeric forms of hydroxyacids is disclosed. The cosmetic conditions and the dermatologic disorders in which the amphoteric compositions and the polymeric compounds may be useful include dry skin, dandruff, acne, keratoses, psoriasis, eczema, pruritus, age spots, lentigines, melasmas, wrinkles, warts, blemished skin, hyperpigmented skin, kyperkeratotic skin, inflammatory dermatoses, skin changes associated with aging, and skin requiring cleansers.
摘要翻译: 公开了用含有α-羟基酸,α-酮酸,相关化合物或聚合形式的羟基酸的两性组合物来减轻化妆品状况和皮肤病症状的预防和治疗。 两性组合物和聚合物可能有用的美容条件和皮肤病学障碍包括干性皮肤,头皮屑,痤疮,角化病,牛皮癣,湿疹,瘙痒,老年斑,斑点,黑斑病,皱纹,疣,瑕疵皮肤,色素沉着 皮肤,皮肤过敏皮肤,炎性皮肤病,与老化有关的皮肤变化,以及需要清洁剂的皮肤。
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公开(公告)号:US5637615A
公开(公告)日:1997-06-10
申请号:US467153
申请日:1995-06-06
申请人: Ruey J. Yu , Eugene J. Van Scott
发明人: Ruey J. Yu , Eugene J. Van Scott
IPC分类号: A61K8/26 , A61K8/27 , A61K8/34 , A61K8/362 , A61K8/365 , A61K8/37 , A61K8/38 , A61K8/41 , A61K8/42 , A61K8/43 , A61K8/44 , A61K8/49 , A61K8/55 , A61K8/58 , A61K8/60 , A61K8/63 , A61K8/64 , A61K8/67 , A61K8/68 , A61K8/81 , A61K8/85 , A61K31/19 , A61K31/191 , A61K31/192 , A61K31/194 , A61K31/195 , A61K31/20 , A61K31/202 , A61K31/365 , A61K31/366 , A61K31/40 , A61K31/405 , A61K31/415 , A61K31/445 , A61K31/66 , A61K31/70 , A61K31/715 , A61K45/06 , A61K47/12 , A61K47/18 , A61K47/24 , A61K47/26 , A61Q5/00 , A61Q5/02 , A61Q7/00 , A61Q15/00 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/08 , A61Q19/10 , B01J19/00 , C02F1/56 , A61K7/48
CPC分类号: A61K9/0014 , A61K31/19 , A61K31/191 , A61K31/192 , A61K31/194 , A61K31/195 , A61K31/20 , A61K31/202 , A61K31/365 , A61K31/366 , A61K31/40 , A61K31/405 , A61K31/415 , A61K31/445 , A61K31/66 , A61K31/70 , A61K31/7012 , A61K31/7048 , A61K31/715 , A61K45/06 , A61K47/12 , A61K47/183 , A61K47/24 , A61K47/26 , A61K8/26 , A61K8/27 , A61K8/347 , A61K8/362 , A61K8/365 , A61K8/37 , A61K8/375 , A61K8/38 , A61K8/41 , A61K8/416 , A61K8/42 , A61K8/43 , A61K8/44 , A61K8/4913 , A61K8/494 , A61K8/4953 , A61K8/4973 , A61K8/55 , A61K8/553 , A61K8/585 , A61K8/60 , A61K8/63 , A61K8/64 , A61K8/671 , A61K8/675 , A61K8/678 , A61K8/68 , A61K8/8152 , A61K8/85 , A61Q15/00 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/004 , A61Q19/007 , A61Q19/008 , A61Q19/02 , A61Q19/08 , A61Q19/10 , A61Q5/00 , A61Q5/006 , A61Q5/02 , A61Q7/00 , B01J19/0013 , C02F1/56 , B01J2219/00063 , B01J2219/00135 , B01J2219/00157 , Y10S514/844 , Y10S514/847 , Y10S514/873 , Y10S514/941 , Y10S514/944
摘要: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin tropic acid.
摘要翻译: 用于明显减少皮肤皱纹和逆转人类面部皮肤老化效果的方法,包括局部施用于皱纹和/或受影响的面部皮肤回肠酸。
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公开(公告)号:US5589505A
公开(公告)日:1996-12-31
申请号:US463724
申请日:1995-06-05
申请人: Ruey J. Yu , Eugene J. Van Scott
发明人: Ruey J. Yu , Eugene J. Van Scott
IPC分类号: A61K8/34 , A61K8/362 , A61K8/365 , A61K8/37 , A61K8/38 , A61K8/42 , A61K8/43 , A61K8/49 , A61K8/60 , A61K8/63 , A61K8/67 , A61K31/19 , A61K31/191 , A61K31/192 , A61K31/194 , A61K31/195 , A61K31/20 , A61K31/202 , A61K31/365 , A61K31/366 , A61K31/40 , A61K31/405 , A61K31/415 , A61K31/445 , A61K31/66 , A61K31/70 , A61K31/715 , A61K45/06 , A61K47/12 , A61K47/18 , A61K47/24 , A61K47/26 , A61Q5/02 , A61Q7/00 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/08 , A61Q19/10 , A61K7/48
CPC分类号: A61Q17/005 , A61K31/19 , A61K31/191 , A61K31/192 , A61K31/194 , A61K31/195 , A61K31/20 , A61K31/202 , A61K31/365 , A61K31/366 , A61K31/40 , A61K31/405 , A61K31/415 , A61K31/445 , A61K31/66 , A61K31/70 , A61K31/7048 , A61K31/715 , A61K45/06 , A61K47/12 , A61K47/183 , A61K47/24 , A61K47/26 , A61K8/347 , A61K8/362 , A61K8/365 , A61K8/37 , A61K8/375 , A61K8/38 , A61K8/42 , A61K8/43 , A61K8/494 , A61K8/4953 , A61K8/4973 , A61K8/60 , A61K8/63 , A61K8/671 , A61K8/675 , A61K9/0014 , A61Q19/00 , A61Q19/02 , A61Q19/08 , A61Q17/00 , A61Q17/04 , A61Q19/007 , A61Q19/008 , A61Q19/10 , A61Q5/02 , A61Q7/00 , Y10S514/844 , Y10S514/847 , Y10S514/873
摘要: A method for visibly reducing a facial wrinkle by topically applying to the wrinkle quinic acid or a topically effective salt thereof, or quinolactone.
摘要翻译: 通过局部施用于皱纹奎尼酸或其局部有效盐或喹诺酮来明显减少面部皱纹的方法。
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公开(公告)号:US5580902A
公开(公告)日:1996-12-03
申请号:US465699
申请日:1995-06-06
申请人: Ruey J. Yu , Eugene J. Van Scott
发明人: Ruey J. Yu , Eugene J. Van Scott
IPC分类号: A61K8/34 , A61K8/362 , A61K8/365 , A61K8/37 , A61K8/38 , A61K8/42 , A61K8/43 , A61K8/49 , A61K8/60 , A61K8/63 , A61K8/67 , A61K31/19 , A61K31/191 , A61K31/192 , A61K31/194 , A61K31/195 , A61K31/20 , A61K31/202 , A61K31/365 , A61K31/366 , A61K31/40 , A61K31/405 , A61K31/415 , A61K31/445 , A61K31/66 , A61K31/70 , A61K31/715 , A61K45/06 , A61K47/12 , A61K47/18 , A61K47/24 , A61K47/26 , A61Q5/02 , A61Q7/00 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/08 , A61Q19/10 , A61K7/48 , A61K31/22
CPC分类号: A61Q17/005 , A61K31/19 , A61K31/191 , A61K31/192 , A61K31/194 , A61K31/195 , A61K31/20 , A61K31/202 , A61K31/365 , A61K31/366 , A61K31/40 , A61K31/405 , A61K31/415 , A61K31/445 , A61K31/66 , A61K31/70 , A61K31/7048 , A61K31/715 , A61K45/06 , A61K47/12 , A61K47/183 , A61K47/24 , A61K47/26 , A61K8/347 , A61K8/362 , A61K8/365 , A61K8/37 , A61K8/375 , A61K8/38 , A61K8/42 , A61K8/43 , A61K8/494 , A61K8/4953 , A61K8/4973 , A61K8/60 , A61K8/63 , A61K8/671 , A61K8/675 , A61K9/0014 , A61Q19/00 , A61Q19/02 , A61Q19/08 , A61Q17/00 , A61Q17/04 , A61Q19/007 , A61Q19/008 , A61Q19/10 , A61Q5/02 , A61Q7/00 , Y10S514/844 , Y10S514/847 , Y10S514/873
摘要: A method for visibly reducing a facial wrinkle by topically applying to the wrinkle ethyl pyruvate.
摘要翻译: 通过局部施用于丙酮酸皱纹乙烯,明显减少面部皱纹的方法。
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公开(公告)号:US5571841A
公开(公告)日:1996-11-05
申请号:US470434
申请日:1995-06-06
申请人: Ruey J. Yu , Eugene J. Van Scott
发明人: Ruey J. Yu , Eugene J. Van Scott
IPC分类号: A61K8/34 , A61K8/362 , A61K8/365 , A61K8/37 , A61K8/38 , A61K8/42 , A61K8/43 , A61K8/49 , A61K8/60 , A61K8/63 , A61K8/67 , A61K31/19 , A61K31/191 , A61K31/192 , A61K31/194 , A61K31/195 , A61K31/20 , A61K31/202 , A61K31/365 , A61K31/366 , A61K31/40 , A61K31/405 , A61K31/415 , A61K31/445 , A61K31/66 , A61K31/70 , A61K31/715 , A61K45/06 , A61K47/12 , A61K47/18 , A61K47/24 , A61K47/26 , A61Q5/02 , A61Q7/00 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/08 , A61Q19/10 , A61K7/48
CPC分类号: A61Q17/005 , A61K31/19 , A61K31/191 , A61K31/192 , A61K31/194 , A61K31/195 , A61K31/20 , A61K31/202 , A61K31/365 , A61K31/366 , A61K31/40 , A61K31/405 , A61K31/415 , A61K31/445 , A61K31/66 , A61K31/70 , A61K31/7048 , A61K31/715 , A61K45/06 , A61K47/12 , A61K47/183 , A61K47/24 , A61K47/26 , A61K8/347 , A61K8/362 , A61K8/365 , A61K8/37 , A61K8/375 , A61K8/38 , A61K8/42 , A61K8/43 , A61K8/494 , A61K8/4953 , A61K8/4973 , A61K8/60 , A61K8/63 , A61K8/671 , A61K8/675 , A61K9/0014 , A61Q19/00 , A61Q19/02 , A61Q19/08 , A61Q17/00 , A61Q17/04 , A61Q19/007 , A61Q19/008 , A61Q19/10 , A61Q5/02 , A61Q7/00 , Y10S514/844 , Y10S514/847 , Y10S514/873
摘要: Composition and method for enhancing therapeutic effects of topically applied agents are disclosed. The cosmetic or therapeutic composition may include one or more of cosmetic or pharmaceutical agents present in a total amount of from 0.01 to 40 percent and one or more of hydroxycarboxylic acids or related compounds present in a total amount of from 0.01 to 99 percent by weight of the total composition. The cosmetic and pharmaceutical agents may include but not limited to age spots, wrinkles and keratoses removing agents; vitamins; aloes; sun screens; tanning, depigmenting and shampooing agents; antiyeasts; antifungal, antibacterial and antiviral agents; topical bronchial dilators and topical cardiovascular agents; hormonal agents; vasodilators; retinoids and other dermatological agents. The hydroxycarboxylic acids and related compounds include organic alpha and beta hydroxycarboxylic acids, alpha and beta ketocarboxylic acids and salts thereof. Topical application of the cosmetic or therapeutic composition has been found to achieve a substantial increase in cosmetic or therapeutic effect of the active ingredient in humans and domesticated animals.
摘要翻译: 公开了用于增强局部施用剂的治疗效果的组合物和方法。 化妆品或治疗组合物可以包括以总量为0.01至40%的一种或多种化妆品或药剂,以及一种或多种羟基羧酸或相关化合物的总量为0.01-99重量% 总组成。 化妆品和药剂可以包括但不限于老年斑,皱纹和角质消除剂; 维生素; 芦荟 遮阳板 鞣制,脱色和洗发剂; 抗衰老 抗真菌,抗菌和抗病毒剂; 局部支气管扩张剂和局部心血管剂; 荷尔蒙剂; 血管扩张剂 维甲酸和其他皮肤病药。 羟基羧酸和相关化合物包括有机α和β羟基羧酸,α和β酮羧酸及其盐。 发现化妆品或治疗组合物的局部应用已经实现了活性成分在人和驯养动物中的美容效果或治疗效果的显着增加。
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