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    HEMODIALYSIS CATHETER SLEEVE
    12.
    发明申请
    HEMODIALYSIS CATHETER SLEEVE 审中-公开
    HEMODIALYSIS导管套管

    公开(公告)号：US20170072129A1

    公开(公告)日：2017-03-16

    申请号：US15257252

    申请日：2016-09-06

    Applicant: Surmodics, Inc.

    Inventor： Joram Slager ,  Joe McGonigle ,  Anh Tri La ,  David E. Babcock ,  Bruce Jelle ,  Aleksey Kurdyumov ,  Timothy M. Kloke ,  Charlie Olson ,  Gary Maharaj ,  Nathan Lockwood

    IPC: A61M1/36 ,  A61M39/02 ,  A61M25/10

    Abstract: A hemodialysis vascular access device includes a proximal end sized and shaped to sealably couple to a hemodialysis catheter, a movable structure coupled to the proximal end, a fixation structure coupled to the movable region and sized and shaped for fixation on a patient, an elongated sleeve coupled to the fixation structure and sized and shaped for insertion into a patient's vasculature, and a valve at a distal end of the internal lumen. When a hemodialysis catheter is inserted into the device and coupled to the proximal end, distal movement of the proximal end relative to the fixation structure biases a distal end of the hemodialysis catheter from a position inside the elongated sleeve through a valve out of the device and into the patient's blood.

    Abstract translation: 血液透析血管通路装置包括尺寸和形状可密封地连接到血液透析导管的近端，耦合到近端的可移动结构，联接到可移动区域的尺寸和形状用于固定在患者身上的细长套筒 耦合到所述固定结构，并且其尺寸和形状用于插入到患者的脉管系统中，以及在所述内腔的远端处的阀。 当血液透析导管插入装置并且联接到近端时，近端相对于固定结构的远端运动通过穿过装置的阀将细胞套筒内的位置偏离血液透析导管的远端， 进入病人的血液。

    LUBRICIOUS MEDICAL DEVICE COATING WITH LOW PARTICULATES
    13.
    发明申请
    LUBRICIOUS MEDICAL DEVICE COATING WITH LOW PARTICULATES 有权

    公开(公告)号：US20210220525A1

    公开(公告)日：2021-07-22

    申请号：US17161396

    申请日：2021-01-28

    Applicant: Surmodics, Inc.

    Inventor： David E. Babcock

    IPC: A61L29/08 ,  A61L27/34 ,  A61L29/14 ,  A61L31/10

    Abstract: Embodiments of the invention include lubricious medical device coatings. In an embodiment the invention includes a coating for a medical device including a first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group; and a first cross-linking agent comprising at least two photoreactive groups; a second layer disposed on the first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group; a second cross-linking agent comprising at least two photoreactive groups; and a polymer comprising polyacrylamide, the polymer derivatized with at least one photoreactive group. Other embodiments are included herein.

    Article coatings including oligomerized polyphenol layer and biological methods of use
    15.
    发明授权
    Article coatings including oligomerized polyphenol layer and biological methods of use 有权

    公开(公告)号：US10201637B2

    公开(公告)日：2019-02-12

    申请号：US15502345

    申请日：2015-08-06

    Applicant: SURMODICS, INC.

    Inventor： David E. Babcock ,  Sean Lundquist ,  Gary Opperman ,  Adriyn Torguson ,  Tim Jentz

    IPC: A61L29/08 ,  A61L29/06 ,  A61L29/16 ,  G01N33/543

    Abstract: Embodiments of the disclosure include coatings comprising an oligomerized polyphenol layer. The oligomerized polyphenol layer can be used as an intermediate coated layer on a medical device that hydrogen bonds to a synthetic or natural polymer, which in turn can be used as a top coat or further associated with another coated layer. The multilayered coatings can provide properties such as hemocompatibility or lubricity. In other embodiments, the oligomerized polyphenol layer is used on a medical device as a hemostatic layer configured to contact blood and promote coagulation. The oligomerized polyphenol layer can also be used on the inner surface (e.g., inner diameter) of a medical device to prevent bacterial adherence. The oligomerized polyphenol layer can also be used on the surface of a in vitro diagnostic article, or a cell culture device to, promote adsorption of a biological molecule.

    LUBRICIOUS MEDICAL DEVICE COATING WITH LOW PARTICULATES
    16.
    发明申请
    LUBRICIOUS MEDICAL DEVICE COATING WITH LOW PARTICULATES 有权
    具有低颗粒度的润滑性医疗器械涂层

    公开(公告)号：US20160271300A1

    公开(公告)日：2016-09-22

    申请号：US15165650

    申请日：2016-05-26

    Applicant: SurModics, Inc.

    Inventor： David E. Babcock

    IPC: A61L29/08 ,  A61L29/14

    CPC classification number: A61L29/085 ,  A61L27/34 ,  A61L29/14 ,  A61L31/10 ,  A61L2400/10 ,  A61L2420/06 ,  A61L2420/08 ,  C08L39/06

    Abstract: Embodiments of the invention include lubricious medical device coatings. In an embodiment the invention includes a coating for a medical device including a first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group; anda first cross-linking agent comprising at least two photoreactive groups; a second layer disposed on the first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group; a second cross-linking agent comprising at least two photoreactive groups; and a polymer comprising polyacrylamide, the polymer derivatized with at least one photoreactive group. Other embodiments are included herein.

    Abstract translation: 包含至少两个光反应性基团的第一交联剂; 设置在第一层上的第二层包含用光反应性基团衍生的聚乙烯吡咯烷酮; 包含至少两个光反应性基团的第二交联剂; 和包含聚丙烯酰胺的聚合物，所述聚合物用至少一种光反应性基团衍生化。 本文还包括其它实施例。

    LUBRICIOUS MEDICAL DEVICE COATING WITH LOW PARTICULATES
    17.
    发明公开
    LUBRICIOUS MEDICAL DEVICE COATING WITH LOW PARTICULATES 审中-公开

    公开(公告)号：US20240342345A1

    公开(公告)日：2024-10-17

    申请号：US18412843

    申请日：2024-01-15

    Applicant: Surmodics, Inc.

    Inventor： David E. Babcock

    IPC: A61L29/08 ,  A61L27/34 ,  A61L29/14 ,  A61L31/10

    CPC classification number: A61L29/085 ,  A61L27/34 ,  A61L29/14 ,  A61L31/10 ,  A61L2400/10 ,  A61L2420/06 ,  A61L2420/08

    Abstract: Embodiments of the invention include lubricious medical device coatings. In an embodiment the invention includes a coating for a medical device including a first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group; and a first cross-linking agent comprising at least two photoreactive groups; a second layer disposed on the first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group; a second cross-linking agent comprising at least two photoreactive groups; and a polymer comprising polyacrylamide, the polymer derivatized with at least one photoreactive group. Other embodiments are included herein.

    Lubricious medical device coating with low particulates
    20.
    发明授权
    Lubricious medical device coating with low particulates 有权

    公开(公告)号：US10905802B2

    公开(公告)日：2021-02-02

    申请号：US15643564

    申请日：2017-07-07

    Applicant: Surmodics, Inc.

    Inventor： David E. Babcock

    IPC: A61L29/08 ,  A61L31/10 ,  A61L27/34 ,  A61L29/14

    Abstract: Embodiments of the invention include lubricious medical device coatings. In an embodiment the invention includes a coating for a medical device including a first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group; and a first cross-linking agent comprising at least two photoreactive groups; a second layer disposed on the first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group; a second cross-linking agent comprising at least two photoreactive groups; and a polymer comprising polyacrylamide, the polymer derivatized with at least one photoreactive group. Other embodiments are included herein.

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