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公开(公告)号：US20100177185A1
公开(公告)日：2010-07-15
申请号：US12664827
申请日：2007-06-18
CPC分类号： A61B90/36 , A61B34/20 , A61B90/20 , A61B2034/2055 , A61B2090/366 , A61B2090/3762
摘要： The application concerns a method of integrating image information (3, 5, 8, 9) from an external source, e.g. an imaging device (1), and an operating microscope (2) before or during an operative procedure on an object (18) or body parts of a patient comprising: positioning an operating microscope (2) before or in the course of said operative procedure at an operative location relative to the patient (18); establishing the spatial relationship among the image information, the patient (18), and the focal plane of a projector (7) or the projection space or the projector (7) itself; introducing the image information and spatial relationship to a computer and reformatting the image information to generate a computer-generated image of the body part at a determined area or plane related to or directly on the surface of the object (18); and projecting the computer-generated image onto the object (18) or patient for coordinated viewing (12) of the computer-generated image and the patient.
摘要翻译： 该应用涉及一种从外部源（例如，图像信号）集成图像信息（3,5,8,9）的方法。 成像装置（1）和操作显微镜（2），其在对象（18）或患者身体部位的手术过程之前或期间包括：在所述手术过程之前或过程中定位手术显微镜（2） 在相对于患者（18）的操作位置处; 建立图像信息，患者（18）和投影仪（7）或投影空间或投影仪（7）本身的焦平面之间的空间关系; 将图像信息和空间关系引入计算机并重新格式化图像信息，以在与物体（18）的表面相关或直接在所述物体（18）的确定的区域或平面上生成身体部位的计算机生成的图像; 以及将所述计算机生成的图像投影到所述对象（18）或患者身上以协调地观看（12）所述计算机生成的图像和所述患者。
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12.发明申请Process for the fermentative production of L-amino acids by attenuation of the poxB gene 审中-公开通过痘痘基因的减毒发酵生产L-氨基酸的方法公开(公告)号：US20050196848A1
公开(公告)日：2005-09-08
申请号：US11111831
申请日：2005-04-22
申请人： Nicole Dusch , Brigitte Bathe , Jorn Kalinowski , Alfred Puhler , Bettina Mockel , Anke Weissenborn , Walter Pfefferle
发明人： Nicole Dusch , Brigitte Bathe , Jorn Kalinowski , Alfred Puhler , Bettina Mockel , Anke Weissenborn , Walter Pfefferle
IPC分类号： C12N15/09 , C12N1/21 , C12N9/02 , C12N15/31 , C12N15/53 , C12P13/08 , C12R1/15 , C12Q1/68 , C07H21/04 , C12N1/20 , C12N9/10 , C12N15/74
CPC分类号： C12N9/0008
摘要： An isolated polynucleotide containing a polynucleotide sequence selected from the group a) polynucleotide which is at least 70% identical to a polynucleotide which codes for a polypeptide containing the amino acid sequence of SEQ ID no. 2, b) polynucleotide which codes for a polypeptide which contains an amino acid sequence which is at least 70% identical to the amino acid sequence of SEQ ID no. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b) and d) polynucleotide containing at least 15 successive bases of the polynucleotide sequence of a), b) or c), and a process for the fermentative production of L-amino acids by attenuation of the poxB gene.
摘要翻译： 一种分离的多核苷酸，其含有多核苷酸序列，所述多核苷酸序列选自a）多核苷酸，其与编码含有SEQ ID NO：1的氨基酸序列的多肽的多核苷酸至少70％相同。 2，b）编码多肽的多核苷酸，其含有与SEQ ID No：1的氨基酸序列至少70％相同的氨基酸序列。 2）c）与a）或b）的多核苷酸互补的多核苷酸，和d）包含a），b）或c）多核苷酸序列的至少15个连续碱基的多核苷酸，以及发酵生产L - 氨基酸通过减少poxB基因。
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13.发明申请Nucleotide sequence encoding the dapC gene and process for the production of L-lysine 有权编码dapC基因的核苷酸序列和生产L-赖氨酸的方法公开(公告)号：US20050100927A1
公开(公告)日：2005-05-12
申请号：US10745684
申请日：2003-12-29
申请人： Bettina Mockel , Anke Weissenborn , Walter Pfefferle , Michael Hartmann , Jorn Kalinowski , Alfred Puhler
发明人： Bettina Mockel , Anke Weissenborn , Walter Pfefferle , Michael Hartmann , Jorn Kalinowski , Alfred Puhler
CPC分类号： C12P13/08 , C12N9/1096
摘要： The invention relates to an isolated polynucleotide from coryneform bacteria containing at least one polynucleotide sequence selected from the group consisting of a) polynucleotide which is at least 70% identical to a polynucleotide which encodes a polypeptide containing the amino acid sequence according to SEQ ID no. 2, b) polynucleotide which encodes a polypeptide which contains an amino acid sequence which is at least 70% identical to the amino acid sequence of SEQ ID no. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide containing at least 15 successive nucleotides of the polynucleotide sequences of a), b) or c), and to a process for the fermentative production of L-amino acids, in particular L-lysine.
摘要翻译： 本发明涉及来自棒状细菌的分离的多核苷酸，其含有至少一种多核苷酸序列，所述多核苷酸序列选自a）多核苷酸，其与编码含有根据SEQ ID No.3所述的氨基酸序列的多肽的多核苷酸至少70％相同。 2，b）编码多肽的多核苷酸，其含有与SEQ ID NO：1的氨基酸序列至少70％相同的氨基酸序列。 2）c）与a）或b）的多核苷酸互补的多核苷酸，和d）包含a），b）或c）的多核苷酸序列的至少15个连续核苷酸的多核苷酸，以及d）发酵生产的方法 的L-氨基酸，特别是L-赖氨酸。
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14.发明申请CONTRAST AGENT ADMINISTRATION METHOD AND SYSTEM TO MAINTAIN CONTRAST AGENT AT A LOCALIZED SITE OF DELIVERY 审中-公开在本地化的交付地点维护对比剂的对比剂代理管理方法和系统公开(公告)号：US20120041306A1
公开(公告)日：2012-02-16
申请号：US12855157
申请日：2010-08-12
CPC分类号： A61K41/0047 , A61B5/055 , A61B5/415 , A61B5/418 , A61B6/481 , A61B2018/1425 , A61B2018/1869 , A61B2018/2005 , A61B2090/3933 , A61B2090/3954 , A61K41/00 , A61K49/0002 , A61M31/005 , A61N7/02
摘要： In a method and system for administering a dispersible medical agent to a subject, a volume of medical agent is delivered in vivo to a subject in a substantially non-dispersed state, at a localized site in tissue of the subject. Contemporaneously with administration of the medical agent to the localized site, energy from an energy source is introduced into only adjacent tissue surrounding the localized site. The energy produces a cellular modification of the adjacent tissue that makes the adjacent tissue substantially impermeable to passage of the medical agent therethrough, so the medical agent is encapsulated and is prevented from dispersing into tissue outside of the encapsulation.
摘要翻译： 在用于向受试者施用可分散医药的方法和系统中，在受试者的组织中的局部位置处，将体积的医用试剂在体内以基本上非分散状态递送至受试者。 同时将医疗剂施用于局部位置，来自能量源的能量被引入仅在局部位点周围的相邻组织。 能量产生相邻组织的细胞改性，使相邻组织基本上不透液体通过药剂，因此药剂被包封并被防止分散到包封外部的组织中。
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15.发明申请METHOD AND ORIENTATION DEVICE FOR MARKING A PREDETERMINED GUIDE PATH OF A MEDICAL INSTRUMENT 审中-公开用于标记医疗仪器预测指南路径的方法和方向设备公开(公告)号：US20120022508A1
公开(公告)日：2012-01-26
申请号：US13178863
申请日：2011-07-08
申请人： Patrick Gross , Martin Requardt , Anke Weissenborn
发明人： Patrick Gross , Martin Requardt , Anke Weissenborn
IPC分类号： A61B17/00
CPC分类号： A61B17/3403 , A61B10/0233 , A61B90/13 , A61B2017/3405 , A61B2034/107 , A61B2034/2048
摘要： In a method for marking a predetermined guide path of a medical instrument in particular a needle, at least one guide path having an angle relative to vertical is indicated by means of at least one adjustable indicator unit such as a light source, and a one-dimensional or two-dimensional inclination sensor is used to adjust the at least one indicator unit with regard to the angle relative to vertical.
摘要翻译： 在用于标记医疗器械特别是针的预定引导路径的方法中，通过至少一个可调整的指示器单元（例如光源）来指示至少一个相对于垂直方向具有角度的引导路径， 三维或二维倾斜传感器用于相对于垂直于角度的角度来调节至少一个指示器单元。
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公开(公告)号：US20110226260A1
公开(公告)日：2011-09-22
申请号：US13050144
申请日：2011-03-17
申请人： Hanns Eder , Anke Weissenborn
发明人： Hanns Eder , Anke Weissenborn
IPC分类号： A61G15/00
CPC分类号： G01R33/34007 , A61B5/0555 , A61B90/14 , A61B2017/00911 , A61B2090/374 , G01R33/34084 , G01R33/3415
摘要： A local coil positioning arrangement is proposed for positioning at least one local coil at an adjustable distance from a Mayfield head fixing arrangement. The local coil positioning arrangement has a local coil holder for accommodating a local coil and a fixing arrangement for fixing the local coil holder at an adjustable distance to the head fixing arrangement.
摘要翻译： 提出了一种局部线圈定位装置，用于将至少一个局部线圈定位在距离Mayfield头固定装置可调节的距离处。 本地线圈定位装置具有用于容纳本地线圈的局部线圈架和用于将本地线圈架固定在与头固定装置可调距离的固定装置。
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17.发明授权Nucleotide sequence encoding the dapC gene and process for the production of L-lysine 有权编码dapC基因的核苷酸序列和生产L-赖氨酸的方法公开(公告)号：US07759056B2
公开(公告)日：2010-07-20
申请号：US10745684
申请日：2003-12-29
申请人： Bettina Möckel , Anke Weissenborn , Walter Pfefferle , Michael Hartmann , Jörn Kalinowski , Alfred Pühler
发明人： Bettina Möckel , Anke Weissenborn , Walter Pfefferle , Michael Hartmann , Jörn Kalinowski , Alfred Pühler
CPC分类号： C12P13/08 , C12N9/1096
摘要： The invention relates to an isolated polynucleotide from coryneform bacteria containing at least one polynucleotide sequence selected from the group consisting of a) polynucleotide which is at least 70% identical to a polynucleotide which encodes a polypeptide containing the amino acid sequence according to SEQ ID no. 2, b) polynucleotide which encodes a polypeptide which contains an amino acid sequence which is at least 70% identical to the amino acid sequence of SEQ ID no. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide containing at least 15 successive nucleotides of the polynucleotide sequences of a), b) or c), and to a process for the fermentative production of L-amino acids, in particular L-lysine.
摘要翻译： 本发明涉及来自棒状细菌的分离的多核苷酸，其含有至少一种多核苷酸序列，所述多核苷酸序列选自a）多核苷酸，其与编码含有根据SEQ ID No.3所述的氨基酸序列的多肽的多核苷酸至少70％相同。 2，b）编码多肽的多核苷酸，其含有与SEQ ID NO：1的氨基酸序列至少70％相同的氨基酸序列。 2）c）与a）或b）的多核苷酸互补的多核苷酸，和d）包含a），b）或c）的多核苷酸序列的至少15个连续核苷酸的多核苷酸，以及d）发酵生产的方法 的L-氨基酸，特别是L-赖氨酸。
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公开(公告)号：US20060067475A1
公开(公告)日：2006-03-30
申请号：US11231365
申请日：2005-09-20
申请人： Thomas Bauch , Anke Weissenborn
发明人： Thomas Bauch , Anke Weissenborn
IPC分类号： H05G1/54
CPC分类号： A61B6/105
摘要： A safety device for an imaging medical apparatus comprising a patient entrance, in particular for a computer tomograph, a nuclear spin tomograph, a PET apparatus or a mobile x-ray apparatus such as for example a C-arc or a fluoroscope, wherein a proximity or contact detector is arranged in the area of the patient entrance. Furthermore, a braking device for a system comprising such an imaging medical apparatus and a patient carrier, which can be moved relative to each other, and to correspondingly equipped imaging medical apparatus.
摘要翻译： 一种用于成像医疗装置的安全装置，包括患者入口，特别是用于计算机断层摄影机，核自旋断层摄影机，PET装置或移动式X射线装置，例如C弧或荧光镜，其中接近 或接触检测器布置在患者入口的区域中。 此外，包括这样的成像医疗装置和可以相对于彼此移动的患者托架的系统的制动装置以及相应配备的成像医疗装置。
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19.发明授权公开(公告)号：US08436617B2
公开(公告)日：2013-05-07
申请号：US12698282
申请日：2010-02-02
申请人： Wolfgang Renz , Anke Weissenborn
发明人： Wolfgang Renz , Anke Weissenborn
CPC分类号： G01R33/287 , A61B5/055 , A61B2017/00911 , G01R33/288
摘要： A compensation device to reduce the electromagnetic field load due to the presence of a medical intervention apparatus in magnetic resonance examinations, has: a control device that has a radio-frequency input and a radio-frequency output, an injection device that is connected with the radio-frequency output and that injects the radio-frequency power delivered by the control device into the medical intervention apparatus, a measurement device that measures at least one electrical variable at the intervention apparatus, and a regulator that is connected with the control device and the measurement device. The regulator adjusts the control device to deliver the radio-frequency power so that the electrical variable at the intervention apparatus is reduced.
摘要翻译： 一种用于在磁共振检查中由于医疗介入装置的存在而减小电磁场负荷的补偿装置具有：具有射频输入和射频输出的控制装置，与 射频输出，其将由控制装置输送的射频功率注入到医疗介入装置中，测量装置，其在介入装置处测量至少一个电变量;以及调节器，其与控制装置和 测量装置。 调节器调节控制装置以传递射频功率，使得介入装置的电变量减小。
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20.发明申请公开(公告)号：US20100194391A1
公开(公告)日：2010-08-05
申请号：US12698282
申请日：2010-02-02
申请人： Wolfgang Renz , Anke Weissenborn
发明人： Wolfgang Renz , Anke Weissenborn
IPC分类号： G01R33/44
CPC分类号： G01R33/287 , A61B5/055 , A61B2017/00911 , G01R33/288
摘要： A compensation device to reduce the electromagnetic field load due to the presence of a medical intervention apparatus in magnetic resonance examinations, has: a control device that has a radio-frequency input and a radio-frequency output, an injection device that is connected with the radio-frequency output and that injects the radio-frequency power delivered by the control device into the medical intervention apparatus, a measurement device that measures at least one electrical variable at the intervention apparatus, and a regulator that is connected with the control device and the measurement device. The regulator adjusts the control device to deliver the radio-frequency power so that the electrical variable at the intervention apparatus is reduced.
摘要翻译： 一种用于在磁共振检查中由于医疗介入装置的存在而减小电磁场负荷的补偿装置具有：具有射频输入和射频输出的控制装置，与 射频输出，其将由控制装置输送的射频功率注入到医疗介入装置中，测量装置，其在介入装置处测量至少一个电变量;以及调节器，其与控制装置和 测量装置。 调节器调节控制装置以传递射频功率，使得介入装置的电变量减小。
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