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165 条记录 (耗时 0.042 秒)

    Cardiac output controller
    11.
    发明授权
    Cardiac output controller 有权
    心输出控制器

    公开(公告)号：US06298268B1

    公开(公告)日：2001-10-02

    申请号：US09254902

    申请日：1999-03-12

    申请人： Shlomo Ben-Haim ,  Nissim Darvish ,  Yuval Mika ,  Maier Fenster

    发明人： Shlomo Ben-Haim ,  Nissim Darvish ,  Yuval Mika ,  Maier Fenster

    IPC分类号： A61N1365

    CPC分类号： A61N1/36514 ,  A61B2017/00243 ,  A61B2017/0243 ,  A61N1/056 ,  A61N1/3627 ,  A61N1/3655 ,  A61N1/36557 ,  A61N1/36564 ,  A61N1/368

    摘要： This invention is an apparatus for modifying cardiac output of the heart of a subject, including one or more sensors which sense signals responsive to cardiac activity, and a stimulation probe including one or more stimulation electrodes which apply non-excitatory stimulation pulses to a cardiac muscle segment. Signal generation circuitry is coupled to the one or more sensors and the stimulation probe, which circuitry receives the signals from the one or more sensors and generates the non-excitatory stimulation pulses responsive to the signals.

    摘要翻译： 本发明是一种用于修改受试者心脏输出的装置，包括一个或多个感测响应于心脏活动的信号的传感器，以及包括一个或多个刺激电极的刺激探针，所述刺激电极将非兴奋性刺激脉冲应用于心肌 分割。 信号发生电路耦合到一个或多个传感器和刺激探针，该电路接收来自一个或多个传感器的信号，并响应于信号产生非兴奋性刺激脉冲。

    ELECTRICAL MUSCLE CONTROLLER AND PACING WITH HEMODYNAMIC ENHANCEMENT
    16.
    发明申请
    ELECTRICAL MUSCLE CONTROLLER AND PACING WITH HEMODYNAMIC ENHANCEMENT 有权
    电动肌肉控制器和血液动力学增强

    公开(公告)号：US20080140142A1

    公开(公告)日：2008-06-12

    申请号：US11933168

    申请日：2007-10-31

    申请人： Nissim Darvish ,  Bella Felsen ,  Itzik Shemer ,  Judith Kornfield ,  Shlomo Ben-Haim ,  Maier Fenster ,  Yuval Mika

    发明人： Nissim Darvish ,  Bella Felsen ,  Itzik Shemer ,  Judith Kornfield ,  Shlomo Ben-Haim ,  Maier Fenster ,  Yuval Mika

    IPC分类号： A61N1/08

    CPC分类号： A61N1/3627 ,  A61N1/05 ,  A61N1/0587 ,  A61N1/36514 ,  A61N1/36564

    摘要： A method of modifying the force of contraction of at least a portion of a heart chamber is provided. A non-excitatory electric field of given duration is applied, at a delay after an activation of the heart, which increase the force of contraction by at least 5%. Apparatus is also provided for pacing with hemodynamic improvement. Circuitry applies an extended pacing signal to electrodes to pace the heart, the extended pacing signal having an overall duration greater than 8 ms from a time of initiation of application of that portion of the signal that initiates action potential propagation. The signal includes a train of biphasic pulses having pulse durations of at least 1 ms, and the signal has an amplitude that is at least three times as great as a threshold for pacing the heart and that is sufficient neither for cardioversion nor for defibrillation. Other embodiments are also described.

    摘要翻译： 提供了改变心室的至少一部分的收缩力的方法。 给予持续时间的非兴奋性电场在心脏激活后延迟施加，其将收缩力增加至少5％。 还提供了用于具有血液动力学改善的起搏的装置。 电路将扩展的起搏信号施加到电极以对心脏进行调节，所述扩展起搏信号的总持续时间大于从启动动作电位传播的信号部分开始施加的时间大于8ms。 该信号包括具有至少1ms的脉冲持续时间的两列脉冲，并且该信号具有至少三倍于起搏心脏阈值的幅度，并且既不适用于心脏复律也不适用于除颤。 还描述了其它实施例。

    Electrical muscle controller and pacing with hemodynamic enhancement
    20.
    发明授权
    Electrical muscle controller and pacing with hemodynamic enhancement 有权
    电子肌肉控制器和起搏与血液动力学增强

    公开(公告)号：US08321013B2

    公开(公告)日：2012-11-27

    申请号：US11933168

    申请日：2007-10-31

    申请人： Nissim Darvish ,  Bella Felsen ,  Itzhak Shemer ,  Judith Kornfeld ,  Shlomo Ben-Haim ,  Maier Fenster ,  Yuval Mika

    发明人： Nissim Darvish ,  Bella Felsen ,  Itzhak Shemer ,  Judith Kornfeld ,  Shlomo Ben-Haim ,  Maier Fenster ,  Yuval Mika

    IPC分类号： A61N1/00

    CPC分类号： A61N1/3627 ,  A61N1/05 ,  A61N1/0587 ,  A61N1/36514 ,  A61N1/36564

    摘要： A method of modifying the force of contraction of at least a portion of a heart chamber is provided. A non-excitatory electric field of given duration is applied, at a delay after an activation of the heart, which increase the force of contraction by at least 5%. Apparatus is also provided for pacing with hemodynamic improvement. Circuitry applies an extended pacing signal to electrodes to pace the heart, the extended pacing signal having an overall duration greater than 8 ms from a time of initiation of application of that portion of the signal that initiates action potential propagation. The signal includes a train of biphasic pulses having pulse durations of at least 1 ms, and the signal has an amplitude that is at least three times as great as a threshold for pacing the heart and that is sufficient neither for cardioversion nor for defibrillation. Other embodiments are also described.

    摘要翻译： 提供了改变心室的至少一部分的收缩力的方法。 给予持续时间的非兴奋性电场在心脏激活后延迟施加，其将收缩力增加至少5％。 还提供了用于具有血液动力学改善的起搏的装置。 电路将扩展的起搏信号施加到电极以对心脏进行调节，所述扩展起搏信号的总持续时间大于从启动动作电位传播的信号部分开始施加的时间大于8ms。 该信号包括具有至少1ms的脉冲持续时间的两列脉冲，并且该信号具有至少三倍于起搏心脏阈值的幅度，并且既不适用于心脏复律也不适用于除颤。 还描述了其它实施例。