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39 条记录 (耗时 0.063 秒)

    Polynucleotides encoding a novel testis-specific tubulin tyrosine-ligase-like protein, BGS42
    12.
    发明申请
    Polynucleotides encoding a novel testis-specific tubulin tyrosine-ligase-like protein, BGS42 有权
    编码新型睾丸特异性微管蛋白酪氨酸连接酶样蛋白的多核苷酸BGS42

    公开(公告)号：US20060246051A1

    公开(公告)日：2006-11-02

    申请号：US11445988

    申请日：2006-06-02

    申请人： John Feder ,  Shujian Wu ,  Thomas Nelson

    发明人： John Feder ,  Shujian Wu ,  Thomas Nelson

    IPC分类号： C12Q1/68 ,  G01N33/567 ,  C07H21/04 ,  C12P21/06 ,  A61K38/48 ,  C12N9/64 ,  G01N33/53 ,  C07K16/40

    CPC分类号： C12N9/93 ,  A01K2217/05 ,  A01K2217/075 ,  A61K38/00 ,  C07K2319/00 ,  G01N33/57423 ,  G01N2333/9015 ,  Y10S435/81

    摘要： The present invention provides novel polynucleotides encoding BGS-42 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-42 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

    摘要翻译： 本发明提供了编码BGS-42多肽的新型多核苷酸，其片段和同源物。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型BGS-42多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。

    Polynucleotides encoding a novel human neuronal cell adhesion protein, BGS-28, and variants thereof
    13.
    发明申请
    Polynucleotides encoding a novel human neuronal cell adhesion protein, BGS-28, and variants thereof 审中-公开
    编码新型人神经元细胞粘附蛋白的多核苷酸，BGS-28及其变体

    公开(公告)号：US20050048620A1

    公开(公告)日：2005-03-03

    申请号：US10926386

    申请日：2004-08-25

    申请人： Shujian Wu ,  John Feder

    发明人： Shujian Wu ,  John Feder

    IPC分类号： C07H21/04 ,  C07K14/705 ,  C12P21/04

    CPC分类号： C07K14/70503 ,  C07H21/04

    摘要： The present invention provides novel polynucleotides encoding BGS-28 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-28 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

    摘要翻译： 本发明提供了编码BGS-28多肽，其片段和同源物的新型多核苷酸。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型BGS-28多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。

    POLYNUCLEOTIDE ENCODING A NOVEL ACYL COENZYME A, MONOACYLGLYCEROL ACYLTRANSFERASE-3 (MGAT3), AND USES THEREOF
    16.
    发明申请
    POLYNUCLEOTIDE ENCODING A NOVEL ACYL COENZYME A, MONOACYLGLYCEROL ACYLTRANSFERASE-3 (MGAT3), AND USES THEREOF 审中-公开
    多核苷酸编码新型ACYL COENZYME A，单乙酰胆碱酯酶3（MGAT3）及其用途

    公开(公告)号：US20080019958A1

    公开(公告)日：2008-01-24

    申请号：US11779308

    申请日：2007-07-18

    申请人： John Feder ,  Thomas Nelson ,  Jian Chen ,  Rupalie Meegalla ,  Michael Ramaker ,  Dong Cheng

    发明人： John Feder ,  Thomas Nelson ,  Jian Chen ,  Rupalie Meegalla ,  Michael Ramaker ,  Dong Cheng

    IPC分类号： C07K16/18 ,  A61K38/45 ,  C12N1/00 ,  C12P21/02 ,  C12Q1/48 ,  C12N9/10 ,  A61P1/00

    CPC分类号： C12N9/1029

    摘要： The present invention provides novel polynucleotides encoding MGAT3 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel MGAT3 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, such as obesity. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

    摘要翻译： 本发明提供了编码MGAT3多肽的新型多核苷酸，其片段及其同源物。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型MGAT3多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症如肥胖症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。

    POLYNUCLEOTIDES ENCODING A NOVEL HUMAN G-PROTEIN COUPLED RECEPTOR SPLICE VARIANT, HGPRBMY29SV2
    19.
    发明申请
    POLYNUCLEOTIDES ENCODING A NOVEL HUMAN G-PROTEIN COUPLED RECEPTOR SPLICE VARIANT, HGPRBMY29SV2 有权
    编码新型人G蛋白偶联受体SPLICE变体的多核苷酸，HGPRBMY29SV2

    公开(公告)号：US20070196897A1

    公开(公告)日：2007-08-23

    申请号：US11071761

    申请日：2005-03-03

    申请人： John Feder ,  Chandra Ramanathan ,  Gabriel Mintier ,  David Bol ,  Donald Hawken

    发明人： John Feder ,  Chandra Ramanathan ,  Gabriel Mintier ,  David Bol ,  Donald Hawken

    IPC分类号： A61K38/17 ,  C07K14/705 ,  C07H21/04 ,  C12P21/06

    CPC分类号： A61K49/0008 ,  A61K38/00 ,  C07K14/705 ,  C07K16/2863 ,  C07K2317/21 ,  C07K2317/622 ,  Y10S435/975

    摘要： The present invention provides novel polynucleotides encoding HGPRBMY28 and HGPRBMY29 polypeptides, fragments and homologues thereof. The present invention also provides polynucleotides encoding splice variants of HGPRBMY29 polypeptides, HGPRBMY29v1 and HGPRBMY29v2. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel HGPRBMY28, HGPRBMY29, HGPRBMY29v1, and HGPRBMY29v2 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

    摘要翻译： 本发明提供编码HGPRBMY28和HGPRBMY29多肽的新型多核苷酸，其片段及其同源物。 本发明还提供编码HGPRBMY29多肽，HGPRBMY29v1和HGPRBMY29v2的剪接变体的多核苷酸。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型HGPRBMY28，HGPRBMY29，HGPRBMY29v1和HGPRBMY29v2多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。