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公开(公告)号：US08691585B2
公开(公告)日：2014-04-08
申请号：US13150791
申请日：2011-06-01
CPC分类号： G01N33/76 , C07K14/59 , C07K16/26 , G01N33/57434 , G01N33/57449 , G01N2333/59 , Y10S435/971 , Y10S436/811 , Y10S436/814 , Y10S436/818
摘要： The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG in a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.
摘要翻译： 本发明提供了通过确定样品中hCG的早期妊娠相关分子同种型的量来预测受试者的妊娠结局的方法。 本发明还提供了一种用于确定样品中人绒毛膜促性腺激素（hCG）的早期妊娠相关分子同种型的量的方法。 本发明还提供了用于确定样品中早期妊娠相关hCG的量的诊断试剂盒。 本发明另外提供了与人绒毛膜促性腺激素的早期怀孕相关分子同种型特异性结合的抗体。 最后，本发明提供了检测样品中滋养层细胞或非滋养层恶性肿瘤的方法。
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公开(公告)号：US20110308777A1
公开(公告)日：2011-12-22
申请号：US13163385
申请日：2011-06-17
申请人： John F. O'Connor , Roger Dickinson
发明人： John F. O'Connor , Roger Dickinson
IPC分类号： F28F13/00
CPC分类号： H05K7/20172 , F04D17/16 , F04D25/02 , F04D25/08 , F04D25/166 , F04D27/004 , F04D29/281 , F04D29/4233
摘要： A cooling fan module for motivating air flow through an electronics chassis includes an enclosure having an air inlet through which cooling air flow is motivated by at least two centrifugal blowers disposed within the enclosure. The centrifugal blowers operate in parallel to motivate the cooling air flow along a first direction vector, while the respective axes of rotation of the centrifugal blower impellers are in substantial axial alignment with one another, and parallel to the first direction vector.
摘要翻译： 用于激励通过电子底盘的空气流动的冷却风扇模块包括具有空气入口的外壳，冷却空气流通过该空气入口由设置在外壳内的至少两个离心式鼓风机驱动。 离心鼓风机平行操作以沿着第一方向向量激励冷却空气流，同时离心式鼓风机叶轮的各自旋转轴线彼此基本上轴向对准并且平行于第一方向矢量。
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13.发明授权
公开(公告)号：US5526527A
公开(公告)日：1996-06-11
申请号：US131210
申请日：1993-10-01
CPC分类号： H03L7/087 , H03L7/193 , H04B1/405 , H04M1/72502
摘要： Methods and apparatus for frequency synthesization are shown for generating an output signal of desired frequency. The frequency synthesizer includes an oscillator for generating an output signal at the desired frequency in response to a control signal. A first detector compares the output signal to a reference signal and generates a first difference signal representative of the differences, preferably in phase and frequency, between the output and the reference signals. A second detector compares the output signal to the reference signal and generates a second difference signal. A controller generates the control signal in response to either the first or second difference signal. A selector member selects between the first and second detectors to provide either the first or second control signal to the controller in response to a selection signal. A lock detector detects when the output signal and said reference signal are in a predetermined relation and generates the switch signal in response to the detection of the occurrence of such predetermined relation.
摘要翻译： 示出用于产生所需频率的输出信号的用于频率合成的方法和装置。 频率合成器包括用于响应于控制信号产生期望频率的输出信号的振荡器。 第一检测器将输出信号与参考信号进行比较，并产生表示输出和参考信号之间的差异，优选地在相位和频率上的第一差分信号。 第二检测器将输出信号与参考信号进行比较，并产生第二差分信号。 控制器响应于第一或第二差信号产生控制信号。 选择器构件在第一和第二检测器之间选择以响应于选择信号向控制器提供第一或第二控制信号。 锁定检测器检测输出信号和所述参考信号何时处于预定关系，并且响应于检测到这种预定关系的发生而产生开关信号。
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公开(公告)号：US08142147B2
公开(公告)日：2012-03-27
申请号：US12100063
申请日：2008-04-09
CPC分类号： F04D29/4246
摘要： A centrifugal blower having at least one radial plane dividing its scroll into sub-sections which may vary as to cut-off points and axial and radial dimensions as well as axial displacement to meet requirements of individual application system flow paths.
摘要翻译： 具有至少一个径向平面的离心式鼓风机，其具有将其涡旋分割成可以切断点和轴向和径向尺寸以及轴向位移而变化的子部分，以满足各个应用系统流动路径的要求。
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公开(公告)号：US08647051B2
公开(公告)日：2014-02-11
申请号：US12876619
申请日：2010-09-07
申请人： John F. O'Connor , Jan Najman , Michael C. Brauer
发明人： John F. O'Connor , Jan Najman , Michael C. Brauer
IPC分类号： F04D29/30
CPC分类号： F04D29/2216 , F04D29/281 , F04D29/30 , F04D29/329 , F04D29/388
摘要： An impeller for a centrifugal fan includes a hub, impeller blades, and struts for supporting the blades in a circumferential array spaced apart from the hub. The number of struts can equal the number of blades, each strut extended from the hub to support two blades while each blade is supported by one strut nearer to its leading edge and another strut nearer to its trailing edge. Another arrangement features two struts per blade, with one of the struts coupled to the hub and a given blade, and the other strut coupled between the given blade and an adjacent blade. The struts are recessed inwardly from the leading and trailing edges to promote smoother air flow. The blades and struts are provided with aerodynamic thickness profiles to further improve air flow.
摘要翻译： 用于离心风扇的叶轮包括轮毂，叶轮叶片和用于将叶片支撑在与轮毂间隔开的周向阵列中的支柱。 支柱的数量可以等于叶片的数量，每个支柱从轮毂延伸以支撑两个叶片，而每个叶片由靠近其前缘的一个支柱支撑，而另一个支柱更靠近其后缘。 另一个布置具有每个叶片两个支柱，其中一个支柱联接到轮毂和给定的叶片，而另一个支柱联接在给定的叶片和相邻的叶片之间。 支柱从前缘和后缘向内凹入，以促进更平滑的气流。 叶片和支柱设有空气动力学厚度廓线，以进一步改善气流。
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公开(公告)号：US20110064570A1
公开(公告)日：2011-03-17
申请号：US12876619
申请日：2010-09-07
申请人： John F. O'Connor , Jan Najman , Michael C. Brauer
发明人： John F. O'Connor , Jan Najman , Michael C. Brauer
CPC分类号： F04D29/2216 , F04D29/281 , F04D29/30 , F04D29/329 , F04D29/388
摘要： An impeller for a centrifugal fan includes a hub, impeller blades, and struts for supporting the blades in a circumferential array spaced apart from the hub. The number of struts can equal the number of blades, each strut extended from the hub to support two blades while each blade is supported by one strut nearer to its leading edge and another strut nearer to its trailing edge. Another arrangement features two struts per blade, with one of the struts coupled to the hub and a given blade, and the other strut coupled between the given blade and an adjacent blade. The struts are recessed inwardly from the leading and trailing edges to promote smoother air flow. The blades and struts are provided with aerodynamic thickness profiles to further improve air flow.
摘要翻译： 用于离心风扇的叶轮包括轮毂，叶轮叶片和用于将叶片支撑在与轮毂间隔开的周向阵列中的支柱。 支柱的数量可以等于叶片的数量，每个支柱从轮毂延伸以支撑两个叶片，而每个叶片由靠近其前缘的一个支柱支撑，而另一个支柱更靠近其后缘。 另一个布置具有每个叶片两个支柱，其中一个支柱联接到轮毂和给定的叶片，而另一个支柱联接在给定的叶片和相邻的叶片之间。 支柱从前缘和后缘向内凹入，以促进更平滑的气流。 叶片和支柱设有空气动力学厚度廓线，以进一步改善气流。
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公开(公告)号：USD246856S
公开(公告)日：1978-01-03
申请号：US656394
申请日：1976-02-09
申请人： John F. O'Connor
设计人： John F. O'Connor
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公开(公告)号：USD330937S
公开(公告)日：1992-11-10
申请号：US521173
申请日：1990-05-09
申请人： John F. O'Connor
设计人： John F. O'Connor
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公开(公告)号：US4995787A
公开(公告)日：1991-02-26
申请号：US408744
申请日：1989-09-18
申请人： John F. O'Connor
发明人： John F. O'Connor
CPC分类号： F04D29/326 , F04D29/384 , F04D29/386
摘要： An axial flow air impeller for automotive radiator fan use and the like comprising a hub carrying a plurality of integrally formed similar circumaxially spaced and generally radially outwardly projecting air moving blades. Each blade has a root end portion integral with the hub and a radially outwardly disposed tip end portion with smoothly curving leading and trailing edges extending therebetween. The leading edge curves substantially forwardly while the trailing edge extends substantially radially to provide for a blade projected width at the tip end portion approximately 40% greater than at the root end portion. The thickness of each blade varies from a maximum at the root end portion to a minimum at the tip end portion with the latter being at least three times the thickness at the blade edge. An integral orifice ring circumscribes the plurality of blades and has a bell mouth at its upstream or downstream end.
摘要翻译： 一种用于汽车散热器风扇的轴向流动空气叶轮及其类似物，其包括承载多个整体形成的类似的外周间隔开并且大致径向向外突出的空气移动叶片的轮毂。 每个叶片具有与毂一体的根部端部和径向向外设置的尖端部分，其平滑弯曲的前缘和后缘在它们之间延伸。 前缘基本向前弯曲，而后缘基本上径向延伸，以提供在尖端部分处的刀片突出宽度大于根端部分的大约40％。 每个叶片的厚度从尖端部分的根部端部处的最大值变化到最小端部处的最小值，后者的厚度是叶片边缘处的厚度的至少三倍。 整体孔环围绕多个叶片并且在其上游或下游端具有喇叭口。
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公开(公告)号：US4063852A
公开(公告)日：1977-12-20
申请号：US653399
申请日：1976-01-28
申请人： John F. O'Connor
发明人： John F. O'Connor
CPC分类号： F01D5/141
摘要： An axial flow impeller for low pressure ratio applications in the range 1.03 and below and comprising a hub carrying a plurality of similar circumaxially arranged air moving blades. Each blade has a root portion attached to the hub and a radially outwardly disposed tip portion. The camber of each blade decreases from root to tip with 0.1203 root camber and .023 tip camber for a ratio of 5.23 to 1. Pitch also decreases from root to tip with a root pitch of 46.degree. and a tip pitch of 27.4.degree. for a ratio of 1.68 to 1. Chord increases from root to tip with a 1.528 inch root chord and a 2.59 inch tip chord for a 1.7 to 1 ratio. The blade camber and chord both change gradually at the blade inner and mid portions with a 35% camber decrease in the outermost 20% of blade span, and with substantially all of the chord increase occurring beyond the blade midpoint.
摘要翻译： 一种用于低压比应用的轴流式叶轮，范围为1.03及以下，并且包括承载多个类似的外围排列的气动叶片的轮毂。 每个叶片具有附接到轮毂的根部部分和径向向外设置的尖端部分。 每个叶片的弧度从根部向下倾斜，0.1203根倾斜度和.023尖端外倾比为5.23至1.根据根间距为46度，针尖间距为27.4度，俯仰角也相应减小。 弦的比例为1.68-1。弦从根到尖端增加，1.528英寸的弦弦和2.59英寸的弦弦为1.7比1。 叶片的外倾和弦在叶片内部和中部逐渐变化，叶片跨度的最外部20％的外倾角减小了35％，并且基本上所有的弦增加超出叶片中点。
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