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    Mobile vehicle sensor array
    11.
    发明申请
    Mobile vehicle sensor array 有权
    移动车载传感器阵列

    公开(公告)号：US20050154503A1

    公开(公告)日：2005-07-14

    申请号：US10756635

    申请日：2004-01-12

    Applicant: Steven Jacobs

    Inventor： Steven Jacobs

    IPC: G05D1/02 ,  G06F7/00

    CPC classification number: G05D1/0242 ,  G05D1/024

    Abstract: An improved sensor array for a mobile vehicle. More particularly, the primary objective of the present invention is to provide mobile vehicle (10) traveling in a forward direction with a sensor array (12). Sensor array (12) comprises a first sensor (16) mounted to mobile vehicle (10) at a maximum lateral distance from said vertical axis of rotation (21) near a first side of mobile vehicle (10) and a second sensor (18) mounted to mobile vehicle (10) at a maximum lateral distance from said vertical axis of rotation (21) near a second side of mobile vehicle (10). First sensor (16) and the second sensor (18) emit object detecting beams for detecting an object (39) ahead of mobile vehicle (10). A plurality of other object detecting beams are emitted obliquely to the object detecting beams of sensor (16) and sensor (18). These other beams, in conjunction with the object detecting beams from sensor (16) and sensor (18) form zones of overlapping beam coverage for better detection of objects.

    Abstract translation: 一种用于移动车辆的改进的传感器阵列。 更具体地说，本发明的主要目的是提供一种在前进方向上与传感器阵列（12）一起行进的移动式车辆（10）。 传感器阵列（12）包括安装在移动车辆（10）上的第一传感器（16），所述第一传感器（16）在距移动车辆（10）的第一侧附近的所述垂直旋转轴线（21）的最大横向距离处和第二传感器（18） 以与移动车辆（10）的第二侧附近的所述垂直旋转轴线（21）的最大横向距离安装到移动车辆（10）。 第一传感器（16）和第二传感器（18）发射用于检测移动车辆（10）前方的物体（39）的物体检测光束。 多个其他物体检测光束倾斜地发射到传感器（16）和传感器（18）的物体检测光束。 这些其他光束与来自传感器（16）和传感器（18）的物体检测光束结合形成重叠光束覆盖的区域，以更好地检测物体。

    Valve box
    12.
    发明授权
    Valve box 失效
    阀箱

    公开(公告)号：US06568420B2

    公开(公告)日：2003-05-27

    申请号：US09798632

    申请日：2001-03-02

    Applicant: Daniel John Renn ,  Steven Jacobs

    Inventor： Daniel John Renn ,  Steven Jacobs

    IPC: F16K2712

    CPC classification number: F16K27/12 ,  Y10T137/5762 ,  Y10T137/7043 ,  Y10T137/7062

    Abstract: Valve boxes of this invention comprise a housing including an inner chamber that extends axially through the housing from a housing base. The housing chamber includes a diameter that is defined by a housing sidewall surface that extends outwardly from the base, forming a chamber opening. The chamber opening includes a seal surface that is positioned radially inwardly towards the chamber. The valve box further includes a lid that is positioned over the housing chamber opening. The lid includes a concave center section and a seal surface disposed radially therearound. The lid seal surface is positioned radially towards the chamber, and is placed opposite the chamber opening seal surface. An annular seal is interposed between the housing chamber and lid seal surfaces. The chamber and lid seal surfaces are configured generally perpendicular to the chamber opening, such that internal pressure within the chamber causes the concave center portion to impose a radially outwardly directed pressure onto the lid, thereby further compressing the annular seal to ensure a leak-tight seal.

    Abstract translation: 本发明的阀箱包括壳体，该壳体包括从壳体基部轴向延伸穿过壳体的内腔。 容纳室包括由从基座向外延伸的壳体侧壁表面限定的直径，形成腔室开口。 腔室开口包括朝向腔室径向向内定位的密封表面。 阀盒还包括位于容纳室开口上方的盖子。 盖子包括一个凹入的中心部分和一个放置在其周围的密封表面。 盖密封表面径向地朝向腔室定位，并且与腔室开口密封表面相对放置。 环形密封件插入在容纳室和盖密封表面之间。 室和盖密封表面大致垂直于室开口配置，使得室内的内部压力使得凹入的中心部分将径向向外的压力施加到盖上，从而进一步压缩环形密封件以确保密封 密封。

    Fibronectin Type III Domain Based Scaffold Compositions, Methods and Uses
    14.
    发明申请
    Fibronectin Type III Domain Based Scaffold Compositions, Methods and Uses 有权
    纤连蛋白III型域支架组合物，方法和用途

    公开(公告)号：US20130096019A1

    公开(公告)日：2013-04-18

    申请号：US13595484

    申请日：2012-08-27

    Applicant: Steven Jacobs ,  Karyn O'Neil

    Inventor： Steven Jacobs ,  Karyn O'Neil

    IPC: C07K14/78

    CPC classification number: C07K14/78 ,  C40B40/08 ,  C40B50/06

    Abstract: A protein scaffold based on a consensus sequence of fibronectin type III (FN3) proteins, such as the tenth FN3 repeat from human fibronectin (human Tenascin), including isolated nucleic acids that encode a protein scaffold, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. In particular, protein scaffold molecules binding to IgG have been identified as useful for diagnostic and/or therapeutic applications.

    Abstract translation: 基于纤连蛋白III（FN3）蛋白的共有序列的蛋白质支架，例如来自人纤连蛋白（人腱生蛋白）的第十FN3重复序列，包括编码蛋白质支架的分离的核酸，载体，宿主细胞和制备方法 并且其使用在诊断和/或治疗组合物，方法和装置中具有应用。 特别地，已经鉴定了结合IgG的蛋白质支架分子可用于诊断和/或治疗应用。

    Methods of Predicting Antibody Solubility
    15.
    发明申请
    Methods of Predicting Antibody Solubility 审中-公开
    预测抗体溶解度的方法

    公开(公告)号：US20110189790A1

    公开(公告)日：2011-08-04

    申请号：US12863489

    申请日：2009-01-20

    Applicant: Karyn O'Neil ,  Steven Jacobs ,  Shong-Juin Wu ,  Deldra Bethea ,  Ylqing Feng

    Inventor： Karyn O'Neil ,  Steven Jacobs ,  Shong-Juin Wu ,  Deldra Bethea ,  Ylqing Feng

    IPC: G01N30/02

    CPC classification number: G01N33/6854 ,  B01D15/3809

    Abstract: The invention provides methods for testing and ranking therapeutic antibody candidates for biophysical properties related to solubility and the susceptibility of the antibody to aggregate in aqueous solutions. The methods are useful for selecting among antibody libraries or variants for candidates which can be formulated at high concentrations.

    Abstract translation: 本发明提供了用于测试和评估与溶解度相关的生物物理性质的治疗性抗体候选物和抗体在水溶液中聚集的易感性的方法。 该方法可用于在可以以高浓度配制的候选物之间选择抗体文库或变体。

    MANUALLY DRIVEN DETERMINATION OF A REGION OF INTEREST (ROI) OR A PATH OF INTEREST (POI) FOR A ROBOTIC DEVICE
    16.
    发明申请
    MANUALLY DRIVEN DETERMINATION OF A REGION OF INTEREST (ROI) OR A PATH OF INTEREST (POI) FOR A ROBOTIC DEVICE 审中-公开
    手动驱动一个兴趣区域（ROI）或一个机器人的兴趣之路（POI）的确定

    公开(公告)号：US20100076599A1

    公开(公告)日：2010-03-25

    申请号：US12234633

    申请日：2008-09-20

    Applicant: Steven Jacobs ,  Kipp Knutson ,  David Wood

    Inventor： Steven Jacobs ,  Kipp Knutson ,  David Wood

    IPC: B25J19/02 ,  B25J9/22

    CPC classification number: G05D1/0272 ,  G05D1/0221 ,  G05D1/0255 ,  G05D1/028

    Abstract: A robotic device is manually driven along a perimeter of a Region Of Interest (ROI) or along a Path Of Interest (POI) for future autonomous operation. An Initial Point (IP) is established by identifying a unique machine recognizable feature, for example, a Radio Frequency Identification (RFID) tag located at the IP. The robotic device is then manually driven along the perimeter or along the path and sensors carried by the robotic device collects data to characterize the ROI or POI. The sensors may include sonar, vision systems, laser, or radar devices for measuring relative positions of a wall, stairs, or obstacles. Wheel odometry may be used to track distances traveled and data fusion exercised to combine the odometry data with the sonar and/or laser measurements to model the ROI or POI. Characterization is performed by collecting points along a wall, fitting a line to the points, and finding the intersections of consecutive lines.

    Abstract translation: 机器人装置沿着感兴趣区域（ROI）或沿着感兴趣路径（POI）的周边手动驱动以用于将来的自主操作。 通过识别唯一的机器可识别特征（例如位于IP处的射频识别（RFID））标签来建立初始点（IP）。 然后机器人装置沿着周边或沿着路径手动驱动，并且机器人装置携带的传感器收集数据以表征ROI或POI。 传感器可以包括用于测量墙壁，楼梯或障碍物的相对位置的声纳，视觉系统，激光或雷达装置。 轨迹测距可用于跟踪所行驶的距离和数据融合，以将测距数据与声纳和/或激光测量结合以对ROI或POI进行建模。 通过沿着墙壁收集点，将线拟合到点上并找到连续线的交点来进行表征。

    HINGE ASSEMBLY
    19.
    发明申请
    HINGE ASSEMBLY 有权
    铰链装配

    公开(公告)号：US20150337579A1

    公开(公告)日：2015-11-26

    申请号：US14650880

    申请日：2012-12-17

    Applicant: Steven JACOBS ,  HEWLETT PACKARD DEVELOPMENTCOMPANY L.P.

    Inventor： Steven Jacobs

    IPC: E05D11/08 ,  E05D3/02 ,  G06F1/16 ,  E05D11/00

    CPC classification number: E05D11/082 ,  E05D3/02 ,  E05D11/0081 ,  E05D11/06 ,  E05D11/084 ,  E05Y2900/606 ,  G06F1/1616 ,  G06F1/1681 ,  Y10T16/522 ,  Y10T16/538 ,  Y10T16/53885 ,  Y10T16/54034 ,  Y10T16/54035 ,  Y10T16/54038

    Abstract: A hinge assembly is disclosed herein. An example includes a first knuckle including a first wall that defines a first cavity and second knuckle including a second wall that defines a second cavity. The example also includes a friction element disposed in both the first cavity defined by the first wall of the first knuckle and the second cavity defined by the second wall of the second knuckle to both rotatably and resistively couple the first knuckle to the second knuckle by application of a force directed toward the first wall and the second wall, the friction element including a third wall that defines a third cavity. Modifications and additions to, as well as other examples of, the hinge assembly are also disclosed herein.

    Abstract translation: 本文公开了铰链组件。 一个例子包括第一转向节，其包括限定第一腔的第一壁和包括限定第二腔的第二壁的第二转向节。 该实施例还包括摩擦元件，其设置在由第一转向节的第一壁限定的第一空腔和由第二转向节的第二壁限定的第二腔中，并且通过施加可旋转地和电阻地将第一转向节连接到第二转向节 指向第一壁和第二壁的力，摩擦元件包括限定第三腔的第三壁。 本文还公开了铰链组件的修改和添加以及其他示例。

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