公开(公告)号：US12070743B2

公开(公告)日：2024-08-27

申请号：US17626385

申请日：2020-07-29

Applicant: TECAN TRADING AG

Inventor： Philipp Ott ,  Adrian Sager ,  Thomas Geiges

IPC: B01L3/02

CPC classification number: B01L3/0231 ,  B01L2200/02 ,  B01L2400/0478

Abstract: A displacement device for displacing a displacement volume is disclosed. The device has a first fluid space and a second fluid space. A first piston is arranged in a movable manner within the first fluid space. The first fluid space is connectable to a pipetting device. The first piston is actuatable by an actuation volume of air or of liquid provided by the pipetting device. A second piston is arranged in a movable manner within the second fluid space. The second piston is constructed to displace a displacement volume of a fluid located within the second fluid space when the second piston is actuated. The second piston is actuated in dependence on the first piston that is actuated by the actuation volume. The actuation volume is different from the displacement volume, and a pipetting system has a displacement device and a method of displacing a displacement volume.

公开(公告)号：US20240201219A1

公开(公告)日：2024-06-20

申请号：US18528347

申请日：2023-12-04

Applicant: Tecan Trading AG

Inventor： Michael Keller ,  Thomas Geiges ,  Volfgang Vilaj

IPC: G01N35/10 ,  G01N11/00 ,  G01N13/02

CPC classification number: G01N35/1009 ,  G01N11/00 ,  G01N13/02 ,  G01N2013/0208

Abstract: A method for determining physical parameters of a liquid to be aspirated and/or dispensed by a laboratory automation device comprises: picking up of a pipette with the laboratory automation device; lowering the pipette into a sample container with the laboratory automation device, the sample container containing the liquid; aspirating and dispensing air and liquid with the laboratory automation device in such a way, that a liquid level in the pipette solely rises in a first step and solely lowers in a second step, such that an interior surface of the pipette is wetted with liquid solely one time; and during aspirating and dispensing air and liquid, measuring a pressure curve in the pipette and determining the physical parameters from the pressure curve, the physical parameters comprising at least one of a surface tension, a wetting angle and a viscosity.

公开(公告)号：US10981162B2

公开(公告)日：2021-04-20

申请号：US16309067

申请日：2017-07-19

Applicant: TECAN TRADING AG

Inventor： Philipp Ott ,  Thomas Geiges

IPC: B01L3/02 ,  G01F23/26 ,  G01N35/10 ,  B01L3/00 ,  G01D5/241 ,  G01N35/00 ,  B01L9/00 ,  B25J9/16

Abstract: The invention relates to a pipetting device having an exchangeable pipette tip for suctioning and discharging fluid volumes for use in automated laboratory systems. The invention relates to a pipetting device having a pipette tip detection unit and for detecting a pipette tip on a pipette device of this type. A detection unit detects whether a pipette tip is connected to the pipette tube or determines a characteristic feature of the connected pipette tip. The pipette tip forms at least one portion of a first electrode when the pipette tip is in electrical operative contact with the pipette tube and, e.g., a pipette tip holder, a contact for setting down the pipette tip holder or a working table over which the pipette tube can be moved forms at least one portion of a second electrode.

公开(公告)号：US09488579B2

公开(公告)日：2016-11-08

申请号：US14538422

申请日：2014-11-11

Applicant: TECAN TRADING AG

Inventor： Torleif Ove Bjornson ,  Thomas Geiges

IPC: G01N21/17 ,  G01N21/03 ,  G01N21/13 ,  G01N21/64 ,  G01N21/59 ,  G01N35/00 ,  C12Q1/68 ,  G01N1/28 ,  G01N21/01 ,  G01N21/33 ,  B01L3/02 ,  G01N21/85 ,  G01N35/10

CPC classification number: G01N21/64 ,  B01L3/021 ,  B01L3/0241 ,  G01N1/28 ,  G01N21/01 ,  G01N21/17 ,  G01N21/33 ,  G01N21/645 ,  G01N21/6486 ,  G01N2021/0314 ,  G01N2021/035 ,  G01N2021/8564 ,  G01N2035/1046 ,  G01N2035/1062 ,  G01N2201/0612 ,  G01N2201/062 ,  G01N2201/08 ,  Y10T436/11 ,  Y10T436/119163 ,  Y10T436/143333 ,  Y10T436/2575

Abstract: An optical measuring apparatus and method for analysis of samples contained in liquid drops provided by a liquid handling system has a liquid handling tip. A light source irradiates the liquid drop; a detector measures sample light; and an optics system with first optical elements transmits irradiation light, and a processor processes the measurement signals. The liquid drop is suspended at the liquid handling orifice of the liquid handling tip in a position where the liquid drop is penetrated by a first optical axis defined by the light source and the first optical elements. The liquid drop is physically touched only by the liquid handling tip and the liquid sample inside the liquid handling tip. A mutual adaption of the size and position of the liquid drop with respect to the first optical elements is achieved.

Abstract translation: 用于分析由液体处理系统提供的液滴中包含的样品的光学测量装置和方法具有液体处理尖端。 光源照射液滴; 检测器测量样品光; 并且具有第一光学元件的光学系统透射照射光，并且处理器处理测量信号。 液滴在液体处理尖端的液体处理孔处悬挂在液滴被由光源和第一光学元件限定的第一光轴穿透的位置处。 只有液体处理尖端和液体处理尖端内的液体样品物理地接触液滴。 实现液滴相对于第一光学元件的尺寸和位置的相互适应。

公开(公告)号：US08912007B2

公开(公告)日：2014-12-16

申请号：US13746722

申请日：2013-01-22

Applicant: Tecan Trading AG

Inventor： Torleif Ove Bjornson ,  Thomas Geiges

IPC: G01N21/17 ,  G01N21/64 ,  G01N35/00 ,  C12Q1/68 ,  B01L3/02 ,  G01N15/02 ,  G01N21/33 ,  G01N21/01 ,  G01N35/10 ,  G01N21/85 ,  G01N21/03

CPC classification number: G01N21/17 ,  B01L3/021 ,  B01L3/0241 ,  G01N15/0227 ,  G01N21/01 ,  G01N21/03 ,  G01N21/33 ,  G01N21/49 ,  G01N21/645 ,  G01N2015/0038 ,  G01N2015/0693 ,  G01N2021/0314 ,  G01N2021/035 ,  G01N2021/8564 ,  G01N2035/1046 ,  Y10T436/11 ,  Y10T436/119163 ,  Y10T436/143333 ,  Y10T436/2575

Abstract: An optical measuring apparatus and method for analysis of samples contained in liquid drops provided by a liquid handling system has a liquid handling tip. A light source irradiates the liquid drop; a detector measures sample light; and an optics system with first optical elements transmits irradiation light, and a processor processes the measurement signals. The liquid drop is suspended at the liquid handling orifice of the liquid handling tip in a position where the liquid drop is penetrated by a first optical axis defined by the light source and the first optical elements. The liquid drop is physically touched only by the liquid handling tip and the liquid sample inside the liquid handling tip. A mutual adaption of the size and position of the liquid drop with respect to the first optical elements is achieved.

Abstract translation: 用于分析由液体处理系统提供的液滴中包含的样品的光学测量装置和方法具有液体处理尖端。 光源照射液滴; 检测器测量样品光; 并且具有第一光学元件的光学系统透射照射光，并且处理器处理测量信号。 液滴在液体处理尖端的液体处理孔处悬挂在液滴被由光源和第一光学元件限定的第一光轴穿透的位置处。 只有液体处理尖端和液体处理尖端内的液体样品物理地接触液滴。 实现液滴相对于第一光学元件的尺寸和位置的相互适应。