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    Robotic arm of an automated pipetting system
    1.
    发明授权
    Robotic arm of an automated pipetting system 有权

    公开(公告)号：US11940457B2

    公开(公告)日：2024-03-26

    申请号：US17524217

    申请日：2021-11-11

    Applicant: TECAN TRADING AG

    Inventor： Thomas Geiges

    IPC: B01L3/02 ,  B01L9/00 ,  B25J18/00 ,  G01N35/00 ,  G01N35/10 ,  H01H1/40 ,  H01H3/16

    CPC classification number: G01N35/0099 ,  B01L3/021 ,  B01L9/54 ,  B25J18/00 ,  B01L2300/0645 ,  B01L2300/0663 ,  B01L2300/12 ,  B01L2300/123 ,  B01L2300/126 ,  G01N2035/1013

    Abstract: A robotic arm of an automated pipetting system has a pipetting tip adapter and a slide switch to detect the presence of pipetting tips on the pipetting tip adapter is disclosed. The slide switch has first support member and second support member configured to slide relative to one another between first and second positions along a movement axis, an electrically conducting contact pad arranged on the first support member, an electrically conducting terminal physically attached to second support member in physical contact with the contact pad when support members are in first position, where the terminal is a first resilient wiping member expanding along the movement axis, first wiping member is not in physical contact with the contact pad when support members are in second position, and an electric current can flow between first wiping member and the contact pad when support members are in first position.

    OPTICAL MEASURING APPARATUS AND METHOD FOR THE ANALYSIS OF SAMPLES CONTAINED IN LIQUID DROPS
    4.
    发明申请
    OPTICAL MEASURING APPARATUS AND METHOD FOR THE ANALYSIS OF SAMPLES CONTAINED IN LIQUID DROPS 有权
    光学测量装置及液体液体样品分析方法

    公开(公告)号：US20140206093A1

    公开(公告)日：2014-07-24

    申请号：US13746722

    申请日：2013-01-22

    Applicant: TECAN TRADING AG

    Inventor： Torleif Ove Bjornson ,  Thomas Geiges

    IPC: G01N21/17

    CPC classification number: G01N21/17 ,  B01L3/021 ,  B01L3/0241 ,  G01N15/0227 ,  G01N21/01 ,  G01N21/03 ,  G01N21/33 ,  G01N21/49 ,  G01N21/645 ,  G01N2015/0038 ,  G01N2015/0693 ,  G01N2021/0314 ,  G01N2021/035 ,  G01N2021/8564 ,  G01N2035/1046 ,  Y10T436/11 ,  Y10T436/119163 ,  Y10T436/143333 ,  Y10T436/2575

    Abstract: An optical measuring apparatus and method for analysis of samples contained in liquid drops provided by a liquid handling system has a liquid handling tip. A light source irradiates the liquid drop; a detector measures sample light; and an optics system with first optical elements transmits irradiation light, and a processor processes the measurement signals. The liquid drop is suspended at the liquid handling orifice of the liquid handling tip in a position where the liquid drop is penetrated by a first optical axis defined by the light source and the first optical elements. The liquid drop is physically touched only by the liquid handling tip and the liquid sample inside the liquid handling tip. A mutual adaption of the size and position of the liquid drop with respect to the first optical elements is achieved.

    Abstract translation: 用于分析由液体处理系统提供的液滴中包含的样品的光学测量装置和方法具有液体处理尖端。 光源照射液滴; 检测器测量样品光; 并且具有第一光学元件的光学系统透射照射光，并且处理器处理测量信号。 液滴在液体处理尖端的液体处理孔处悬挂在液滴被由光源和第一光学元件限定的第一光轴穿透的位置处。 只有液体处理尖端和液体处理尖端内的液体样品物理地接触液滴。 实现液滴相对于第一光学元件的尺寸和位置的相互适应。

    Liquid aspiration with volume compensation
    5.
    发明申请
    Liquid aspiration with volume compensation 有权

    公开(公告)号：US20240402207A1

    公开(公告)日：2024-12-05

    申请号：US18733603

    申请日：2024-06-04

    Applicant: Tecan Trading AG

    Inventor： Michael Keller ,  Thomas Geiges

    IPC: G01N35/10

    Abstract: A method for aspirating a liquid with a laboratory automation device comprises: lowering a pipette of the laboratory automation device into a vessel containing the liquid; during lowering, generating an underpressure or overpressure in the pipette with a pressure generating device of the laboratory automation device and measuring a pressure in a pressure distribution system interconnecting the pressure generating device with the pipette; detecting a liquid surface of the liquid in the vessel by evaluating a pressure change of the pressure; calculating a compensation volume from compartment volumes of compartments of the pressure distribution system and/or of the pipette and from pressure losses between the compartments; and aspirating the liquid from the vessel into the pipette by controlling the pressure generating device to aspirate a specific volume altered by the compensation volume.

    Determining physical parameters of a liquid with simulation
    6.
    发明公开
    Determining physical parameters of a liquid with simulation 审中-公开

    公开(公告)号：US20240201208A1

    公开(公告)日：2024-06-20

    申请号：US18527954

    申请日：2023-12-04

    Applicant: Tecan Trading AG

    Inventor： Michael Keller ,  Thomas Geiges ,  Volfgang Vilaj

    IPC: G01N35/00 ,  G01N35/04

    CPC classification number: G01N35/00584 ,  G01N35/04 ,  G01N2035/0434

    Abstract: A method for determining physical parameters of an unknown liquid to be aspirated and/or dispensed by a laboratory automation device comprises: determining physical parameters of a pipette, the physical parameters including geometric parameters of the pipette, which at least include a tip radius of an orifice of the pipette; aspirating and/or dispensing the unknown liquid with a pipette of the laboratory automation device and measuring a measured pressure curve in the pipette during aspirating and/or dispensing; determining the physical parameters of the unknown liquid by minimizing an objective function depending on a difference between a simulated pressure curve and the measured pressure curve, wherein the simulated pressure curve simulates a pressure in the pipette during aspirating and/or dispensing and is calculated based on a physical model of the laboratory automation device including the physical parameters of the pipette.

    Pipetting device and method
    8.
    发明授权
    Pipetting device and method 有权

    公开(公告)号：US12220694B2

    公开(公告)日：2025-02-11

    申请号：US17122470

    申请日：2020-12-15

    Applicant: TECAN TRADING AG

    Inventor： Michael Keller ,  Thomas Geiges

    IPC: B01L3/02

    Abstract: Pipetting device for pipetting a liquid driven by a gaseous working medium, the pipetting device having at least one pipette connector adapted to attach a pipette at a connection opening at least one pressurizing and/or suctioning pressure source, a gas flow connection between said connection opening and at least one pressure source, a flow restriction defining at least a section of said gas flow connection, a first sensor configured to measure a quantity indicative of the temperature of the flow restriction. The invention is further directed to a gas flow connection element for a pipetting device and to a method of pipetting a liquid volume.

    PIPETTING DEVICE AND METHOD
    9.
    发明申请
    PIPETTING DEVICE AND METHOD 有权

    公开(公告)号：US20210187493A1

    公开(公告)日：2021-06-24

    申请号：US17122470

    申请日：2020-12-15

    Applicant: TECAN TRADING AG

    Inventor： Michael KELLER ,  Thomas Geiges

    IPC: B01L3/02

    Abstract: Pipetting device for pipetting a liquid driven by a gaseous working medium, the pipetting device having at least one pipette connector adapted to attach a pipette at a connection opening at least one pressurizing and/or suctioning pressure source, a gas flow connection between said connection opening and at least one pressure source, a flow restriction defining at least a section of said gas flow connection, a first sensor configured to measure a quantity indicative of the temperature of the flow restriction. The invention is further directed to a gas flow connection element for a pipetting device and to a method of pipetting a liquid volume.

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