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    Filtering powder medicament inhaler and application
    11.
    发明授权
    Filtering powder medicament inhaler and application 有权
    过滤粉末药物吸入器及应用

    公开(公告)号：US09339614B2

    公开(公告)日：2016-05-17

    申请号：US13994760

    申请日：2011-12-15

    Applicant: Qingtang Chen ,  Xin Chen

    Inventor： Qingtang Chen ,  Xin Chen

    IPC: A61M11/00 ,  A61M15/00 ,  A61M15/08

    CPC classification number: A61M15/0028 ,  A61M11/003 ,  A61M15/003 ,  A61M15/0035 ,  A61M15/0041 ,  A61M15/08 ,  A61M2202/064

    Abstract: A filtering powdered medicament inhaler comprising a base (1) and an upper base (2). The upper base (2) has arranged therein a separator (62), which is connected at the bottom to a pressure groove (63). The upper base (2) has arranged thereon a hollow tube exterior connector (10) matching a suction tube (131). The hollow tube (19a) and a cavity (9) on one side of the separator (62) are interconnected via conduit (18), or, the hollow tube (19a) is extended for about 8 centimeters to form a mouthpiece. The upper base (2) has arranged in the cavity (9) thereof a filter (121). The base (1) is provided with an external base cover (72) which covers a press-button (5a) so as to reduce air flow into the cavity (9). The medicament inhaling conduit of the inhaler is relatively sealed and allows for rapid entrainment of a sufficient dosage of powdered medicament.

    Abstract translation: 一种过滤粉末状药物吸入器，其包括基部（1）和上部基部（2）。 上基座（2）在其中布置有分隔件（62），其在底部连接到压力槽（63）。 上部基座（2）上布置有与抽吸管（131）相匹配的中空管外部连接器（10）。 中空管（19a）和分离器（62）的一侧上的空腔（9）通过导管（18）互连，或者中空管（19a）延伸约8厘米以形成接口。 上基座（2）在其空腔（9）中布置有过滤器（121）。 基座（1）设置有覆盖按钮（5a）的外部基座盖（72），以减少进入空腔（9）的气流。 吸入器的药物吸入管道相对密封，并允许快速夹带足够剂量的粉末状药物。

    Microfluidic, electrochemical devices
    12.
    发明授权
    Microfluidic, electrochemical devices 有权
    微流控，电化学装置

    公开(公告)号：US09192933B2

    公开(公告)日：2015-11-24

    申请号：US13254967

    申请日：2010-03-08

    Applicant: George M. Whitesides ,  Zhihong Nie ,  Christian Nijhuis ,  Xin Chen ,  Andres W. Martinez ,  Max Narovlyansky

    Inventor： George M. Whitesides ,  Zhihong Nie ,  Christian Nijhuis ,  Xin Chen ,  Andres W. Martinez ,  Max Narovlyansky

    IPC: G01N27/26 ,  B01L3/00 ,  G01N27/327

    CPC classification number: B01L3/5027 ,  B01L3/502 ,  B01L2300/0645 ,  B01L2300/0887 ,  G01N27/3272

    Abstract: Microfluidic, electrochemical devices are described. The microfluidic, electrochemical device comprises one or more electrode(s) on a substrate and a patterned porous, hydrophilic layer having a fluid-impermeable barrier which substantially permeates the thickness of the porous, hydrophilic layer and defines boundaries of one or more hydrophilic channels within the patterned porous, hydrophilic layer, wherein the hydrophilic channel(s) comprises a hydrophilic region which is in fluidic communication with the electrode(s). In some embodiments, the electrodes comprise a working electrode, a counter electrode, and a reference electrode. In some embodiments, the microfluidic, electrochemical device further comprises a fluid sink. The method of assembling the microfluidic, electrochemical device is described. The method of using the device for electrochemical analysis of one or more analytes is also described.

    Abstract translation: 描述了微流体，电化学装置。 微流体电化学装置包括在基底上的一个或多个电极和图案化的多孔亲水层，其具有基本上渗透多孔亲水层的厚度的流体不可渗透屏障，并限定一个或多个亲水性通道的边界 所述图案化的多孔亲水层，其中所述亲水沟道包括与所述电极流体连通的亲水区域。 在一些实施例中，电极包括工作电极，对电极和参考电极。 在一些实施例中，微流体，电化学装置还包括流体槽。 描述了组装微流体，电化学装置的方法。 还描述了使用该装置进行一种或多种分析物的电化学分析的方法。

    Self-regulating pressure source
    13.
    发明授权
    Self-regulating pressure source 有权
    自调压源

    公开(公告)号：US09027336B2

    公开(公告)日：2015-05-12

    申请号：US13420886

    申请日：2012-03-15

    Applicant: Cagdas Denizel Onal ,  Daniela Rus ,  Xin Chen ,  George M. Whitesides

    Inventor： Cagdas Denizel Onal ,  Daniela Rus ,  Xin Chen ,  George M. Whitesides

    IPC: F16D31/02 ,  G05D16/06 ,  F15B21/06

    CPC classification number: G05D16/0636 ,  F15B21/06

    Abstract: Self-regulating pressure source. The pressure source includes a chamber enclosing a chemical monopropellant. A moveable boss is attached to a deformable membrane sealing an air chamber, the moveable boss and air chamber being disposed within the chamber. A catalyst is disposed around the membrane so as to be covered by the boss in a retracted position so that the monopropellant is broken down by the catalyst to produce a gas. The gas pressure will increase within the chamber causing air in the air chamber to compress thereby to pull the boss into the retracted position to cover the catalyst thereby to regulate the pressure within the chamber. The self-regulating pressure source is particularly suited to power fluidic elastomeric actuators.

    Abstract translation: 自调压源。 压力源包括封闭化学单元推进剂的室。 可移动的凸台连接到密封空气室的可变形膜，可移动的凸台和空气室设置在室内。 催化剂设置在膜周围，以便被凸起覆盖在缩回位置，使得单组分推进剂被催化剂分解以产生气体。 在室内气体压力将增加，导致空气室中的空气压缩，从而将凸台拉到缩回位置以覆盖催化剂，从而调节室内的压力。 自调节压力源特别适用于流体弹性致动器。

    METHOD FOR ESTABLISHING COMP COOPERATING SET IN COORDINATED MULTI-POINT COMMUNICATION
    18.
    发明申请
    METHOD FOR ESTABLISHING COMP COOPERATING SET IN COORDINATED MULTI-POINT COMMUNICATION 有权
    在协调多点通信中建立合作伙伴关系的方法

    公开(公告)号：US20130223272A1

    公开(公告)日：2013-08-29

    申请号：US13884368

    申请日：2011-10-27

    Applicant: Xiaofeng Tao ,  Xiaodong Xu ,  Qimei Cui ,  Ping Zhang ,  Xin Chen ,  Hongjia Li ,  Qiang Wang ,  Jie Ni

    Inventor： Xiaofeng Tao ,  Xiaodong Xu ,  Qimei Cui ,  Ping Zhang ,  Xin Chen ,  Hongjia Li ,  Qiang Wang ,  Jie Ni

    IPC: H04W24/10

    CPC classification number: H04W24/10 ,  H04B7/024 ,  H04B7/0626 ,  H04W72/0426 ,  H04W92/20

    Abstract: Disclosed is a method for establishing a CoMP cooperating set in coordinated multi-point communication, the method comprising the steps of: triggering and starting a coordinated multi-point communication process; according to channel state information of all cells in a measurement cell set measured by a UE, determining a candidate CoMP cooperating set; sending a CoMP cooperating set establishment request to eNodeBs of the cooperating cells in the determined candidate CoMP cooperating set; the eNodeBs being of the cooperating cell and receiving the CoMP cooperating set establishment request responding to the CoMP cooperating set establishment request to the eNodeB of the serving cell of the UE, and sending a CoMP cooperating set establishment response to the eNodeB of the serving cell of the UE; the eNodeB of the serving cell of the UE determining a CoMP cooperating set of the UE according to information of the CoMP cooperating set establishment response; and according to a coordinated multi-point communication mode, sharing data information and service bearer information of the UE of the CoMP cooperating set. The present invention guarantees coordinated multi-point joint transmission/reception, decreases the overhead and complexity of the communication system and furthermore reduces the time delay in the information exchange.

    Abstract translation: 公开了一种在协调多点通信中建立CoMP协作集的方法，所述方法包括以下步骤：触发并启动协调的多点通信过程; 根据由UE测量的测量小区集中的所有小区的信道状态信息，确定候选的CoMP协作组; 向确定的候选CoMP协作集中的协作小区的eNodeB发送CoMP协作组建立请求; 所述eNodeB是协作小区，并且将响应于所述CoMP协作组建立请求的所述CoMP协作组建立请求接收到所述UE的所述服务小区的eNodeB，并且向所述服务小区的eNodeB发送CoMP协作集合建立响应 UE; UE的服务小区的eNodeB根据CoMP合作组建立响应的信息确定UE的CoMP协作组; 并且根据协调的多点通信模式，共享CoMP协作组的UE的数据信息和业务承载信息。 本发明保证了协调的多点联合发送/接收，降低了通信系统的开销和复杂性，进而减少了信息交换中的时延。

    Melanocortin receptor-specific peptides for treatment of sexual dysfunction
    19.
    发明授权
    Melanocortin receptor-specific peptides for treatment of sexual dysfunction 有权
    用于治疗性功能障碍的黑皮质素受体特异性肽

    公开(公告)号：US08487073B2

    公开(公告)日：2013-07-16

    申请号：US12952238

    申请日：2010-11-23

    Applicant: Yi-Qun Shi ,  Shubh D. Sharma ,  Wei Yang ,  Xin Chen

    Inventor： Yi-Qun Shi ,  Shubh D. Sharma ,  Wei Yang ,  Xin Chen

    IPC: A61K38/00

    CPC classification number: C07K7/56 ,  A61K38/00 ,  A61K38/12 ,  A61K45/06 ,  C07K14/685

    Abstract: A melanocortin receptor agonist cyclic peptide of the formula where R, x and y are as defined in the specification, compositions and formulations including the peptide of the foregoing formula, and methods of preventing, ameliorating or treating melanocortin receptor-mediated diseases, indications, conditions and syndromes, including sexual dysfunction such as male erectile dysfunction and female sexual dysfunction.

    Abstract translation: 下式的黑皮质素受体激动剂环肽其中R，x和y如说明书中所定义，包括上述式的肽的组合物和制剂，以及预防，改善或治疗黑皮质素受体介导的疾病，适应症，条件 和综合征，包括性功能障碍如男性勃起功能障碍和女性性功能障碍。

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