Human peptidyl-prolyl isomerases
    14.
    发明授权
    Human peptidyl-prolyl isomerases 失效
    人肽基脯氨酰异构酶

    公开(公告)号:US06171843B2

    公开(公告)日:2001-01-09

    申请号:US09088425

    申请日:1998-06-01

    IPC分类号: C12N990

    CPC分类号: C12N9/90

    摘要: The invention provides human peptidyl-prolyl isomerases (HPPIP) and polynucleotides which identify and encode HPPIP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of HPPIP.

    摘要翻译: 本发明提供了鉴定和编码HPPIP的人肽基 - 脯氨酰异构酶(HPPIP)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与HPPIP表达相关的病症的方法。

    Mammalian imidazoline receptor
    16.
    发明授权
    Mammalian imidazoline receptor 失效
    哺乳动物咪唑啉受体

    公开(公告)号:US06475752B1

    公开(公告)日:2002-11-05

    申请号:US09364206

    申请日:1999-07-30

    IPC分类号: C12P2106

    CPC分类号: C07K14/705

    摘要: The invention provide a mammalian nucleic acid molecule and fragments thereof. It also provides for the use of the mammalian nucleic acid molecule for the characterization, diagnosis, evaluation, treatment, or prevention of conditions, diseases and disorders associated with its expression and for the production of a model system. The invention additionally provides expression vectors and host cells for the production of the protein encoded by the mammalian nucleic acid molecule. The invention further provides a mammalian protein or portions thereof. The invention still further provides for the use of the nucleic acid molecule and protein in assays to detect or purify ligands.

    摘要翻译: 本发明提供哺乳动物核酸分子及其片段。 它还提供了哺乳动物核酸分子用于表征,诊断,评估,治疗或预防与其表达相关的病症和病症以及用于模型系统的生产的用途。 本发明另外提供用于产生由哺乳动物核酸分子编码的蛋白质的表达载体和宿主细胞。 本发明还提供哺乳动物蛋白质或其部分。 本发明还进一步提供核酸分子和蛋白质在测定中用于检测或纯化配体的用途。

    Human peptidyl-prolyl isomerases
    18.
    发明授权
    Human peptidyl-prolyl isomerases 失效
    人肽基脯氨酰异构酶

    公开(公告)号:US06524838B1

    公开(公告)日:2003-02-25

    申请号:US09639378

    申请日:2000-08-15

    IPC分类号: C12N990

    CPC分类号: C12N9/90

    摘要: The invention provides human peptidyl-prolyl isomerases (HPPIP) and polynucleotides which identify and encode HPPIP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of HPPIP.

    摘要翻译: 本发明提供了鉴定和编码HPPIP的人肽基 - 脯氨酰异构酶(HPPIP)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与HPPIP表达相关的病症的方法。

    Phosphatidylinositol 4,5-bisphosphate 5-phosphatase
    20.
    发明授权
    Phosphatidylinositol 4,5-bisphosphate 5-phosphatase 有权
    磷脂酰肌醇4,5-二磷酸5-磷酸酶

    公开(公告)号:US06277373B1

    公开(公告)日:2001-08-21

    申请号:US09258643

    申请日:1999-02-26

    IPC分类号: A61K3848

    CPC分类号: C12N9/16 A61K38/00

    摘要: The invention provides a human phosphatidylinositol 4,5-bisphosphate 5-phosphatase (PBPP) and polynucleotides which identify and encode PBPP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of PBPP.

    摘要翻译: 本发明提供了一种人磷酸肌醇4,5-二磷酸5-磷酸酶(PBPP)和鉴定和编码PBPP的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了治疗与PBPP表达相关的疾病的方法。