公开(公告)号：US20070202560A1

公开(公告)日：2007-08-30

申请号：US11360672

申请日：2006-02-24

申请人： Yuji Kikuchi ,  Taiji Nishi ,  Motohiro Fukuda

发明人： Yuji Kikuchi ,  Taiji Nishi ,  Motohiro Fukuda

IPC分类号： C12Q1/54 ,  C12M3/00

CPC分类号： B01L3/502707 ,  B01L3/502746 ,  B01L2200/0668 ,  B01L2200/12 ,  B01L2300/0645 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2400/086 ,  B81B2201/0214 ,  B81B2201/058 ,  B81C1/00071 ,  B81C99/009 ,  B81C2201/034

摘要： A resin microchannel array includes a first substrate having a plurality of depressions, each depression having an inlet port at one end and an outlet port at another end, and walls sectioning the depressions, each wall having a micro groove connecting the depressions, and a second substrate having a flat surface bonded or pressure-contacted to a surface of the first substrate. Spaces created by the depressions and the grooves in a bonded or pressure contacted part between the first substrate and the second substrate serve as flow channels. Each of a width and a depth of the flow channel is within a range of 1 to 50 μm, and a ratio of the width and the depth of the flow channel is within a range of 1:10 to 10:1.

摘要翻译： 树脂微通道阵列包括具有多个凹陷的第一基底，每个凹陷部分在一端具有入口端口和另一端部的出口端口，以及分隔凹陷部分的壁，每个壁具有连接凹部的微凹槽， 衬底，其具有与第一衬底的表面结合或压力接触的平坦表面。 由第一基板和第二基板之间的结合或压力接触部分中的凹陷和凹槽产生的空间用作流动通道。 流路的宽度和深度各自在1〜50μm的范围内，流路的宽度和深度的比例在1:10〜10:1的范围内。

公开(公告)号：US08435782B2

公开(公告)日：2013-05-07

申请号：US12280607

申请日：2007-02-19

申请人： Taiji Nishi ,  Go Tazaki ,  Motohiro Fukuda ,  Michio Yazawa ,  Masayuki Takahashi

发明人： Taiji Nishi ,  Go Tazaki ,  Motohiro Fukuda ,  Michio Yazawa ,  Masayuki Takahashi

IPC分类号： C12M1/14

CPC分类号： C12M23/12 ,  B01L3/5085 ,  B01L3/5088 ,  B01L2300/0829 ,  B01L2300/0851 ,  B01L2300/0858 ,  B01L2300/0893 ,  C12M25/00

摘要： An object of the present invention is to provide a cell culture chamber with which the survival rate of cells to be cultured can be increased, and a method of producing the same. A cell culture chamber according to the present invention includes a mass of projections formed of a plurality of microprojections 1 formed on a surface on which cells are cultured. The width or diameter of each of the microprojections 1 is in a range of 20 nm to 3 μm, and the aspect ratio of each of the microprojections is in a range of 0.2 to 3.0. Thus, there can be provided a cell culture chamber most suitable for the adhesion and differentiation/proliferation of cells to be cultured.

摘要翻译： 本发明的目的是提供一种能够提高培养细胞存活率的细胞培养室及其制造方法。 根据本发明的细胞培养室包括由在其上培养细胞的表面上形成的多个微突出物1形成的突起体。 每个微喷射体1的宽度或直径在20nm至3μm的范围内，并且每个微喷射体的纵横比在0.2至3.0的范围内。 因此，可以提供最适合于待培养细胞的粘附和分化/增殖的细胞培养室。

公开(公告)号：US20090170190A1

公开(公告)日：2009-07-02

申请号：US12280607

申请日：2007-02-19

申请人： Taiji Nishi ,  Go Tazaki ,  Motohiro Fukuda ,  Michio Yazawa ,  Masayuki Takahashi

发明人： Taiji Nishi ,  Go Tazaki ,  Motohiro Fukuda ,  Michio Yazawa ,  Masayuki Takahashi

IPC分类号： C12M1/00 ,  B05D1/32

CPC分类号： C12M23/12 ,  B01L3/5085 ,  B01L3/5088 ,  B01L2300/0829 ,  B01L2300/0851 ,  B01L2300/0858 ,  B01L2300/0893 ,  C12M25/00

摘要： An object of the present invention is to provide a cell culture chamber with which the survival rate of cells to be cultured can be increased, and a method of producing the same. A cell culture chamber according to the present invention includes a mass of projections formed of a plurality of microprojections 1 formed on a surface on which cells are cultured. The width or diameter of each of the microprojections 1 is in a range of 20 nm to 3 μm, and the aspect ratio of each of the microprojections is in a range of 0.2 to 3.0. Thus, there can be provided a cell culture chamber most suitable for the adhesion and differentiation/proliferation of cells to be cultured.

摘要翻译： 本发明的目的是提供一种能够提高培养细胞存活率的细胞培养室及其制造方法。 根据本发明的细胞培养室包括由在其上培养细胞的表面上形成的多个微突出物1形成的突起体。 每个微喷射体1的宽度或直径在20nm至3μm的范围内，并且每个微喷射体的纵横比在0.2至3.0的范围内。 因此，可以提供最适合于待培养细胞的粘附和分化/增殖的细胞培养室。

公开(公告)号：US20090075363A1

公开(公告)日：2009-03-19

申请号：US12298803

申请日：2007-04-25

申请人： Yuji Morimoto ,  Taiji Nishi ,  Taisuke Kamada ,  Go Tazaki ,  Motohiro Fukuda

发明人： Yuji Morimoto ,  Taiji Nishi ,  Taisuke Kamada ,  Go Tazaki ,  Motohiro Fukuda

IPC分类号： C12M3/00 ,  B05D5/10

CPC分类号： C12M23/12 ,  C12M23/16

摘要： To provide a cell culture chamber capable of reproducing a cell function in vivo, and a method of producing the same. The cell culture chamber according to the present invention has a concave-convex pattern formed on the surface on which cells are cultured. A concave portion of the concave-convex pattern includes cell culture portions and micro flow channels communicating with the cell culture portions. The bottom surface of each of the cell culture portions has a width 1.0 to 20 times an equivalent diameter of each of the cultured cells. A cell adhesion-inducing substance is formed only on the bottom surface and the side walls of the concave portion.

摘要翻译： 提供能够在体内再现细胞功能的细胞培养室及其制造方法。 根据本发明的细胞培养室具有形成在其上培养细胞的表面上的凹凸图案。 凹凸图案的凹部包括与细胞培养部连通的细胞培养部和微流路。 每个细胞培养部分的底表面具有每个培养细胞的当量直径的1.0至20倍的宽度。 细胞粘附诱导物质仅形成在凹部的底面和侧壁上。

公开(公告)号：US08652833B2

公开(公告)日：2014-02-18

申请号：US12298803

申请日：2007-04-25

申请人： Yuji Morimoto ,  Taiji Nishi ,  Taisuke Kamada ,  Go Tazaki ,  Motohiro Fukuda

发明人： Yuji Morimoto ,  Taiji Nishi ,  Taisuke Kamada ,  Go Tazaki ,  Motohiro Fukuda

IPC分类号： C12M3/00 ,  B05D5/10 ,  C40B40/00 ,  C04B40/02

CPC分类号： C12M23/12 ,  C12M23/16

摘要： To provide a cell culture chamber capable of reproducing a cell function in vivo, and a method of producing the same. The cell culture chamber according to the present invention has a concave-convex pattern formed on the surface on which cells are cultured. A concave portion of the concave-convex pattern includes cell culture portions and micro flow channels communicating with the cell culture portions. The bottom surface of each of the cell culture portions has a width 1.0 to 20 times an equivalent diameter of each of the cultured cells. A cell adhesion-inducing substance is formed only on the bottom surface and the side walls of the concave portion.

摘要翻译： 提供能够在体内再现细胞功能的细胞培养室及其制造方法。 根据本发明的细胞培养室具有形成在其上培养细胞的表面上的凹凸图案。 凹凸图案的凹部包括与细胞培养部连通的细胞培养部和微流路。 每个细胞培养部分的底表面具有每个培养细胞的当量直径的1.0至20倍的宽度。 细胞粘附诱导物质仅形成在凹部的底面和侧壁上。

公开(公告)号：US20090075366A1

公开(公告)日：2009-03-19

申请号：US11914762

申请日：2006-05-11

申请人： Go Tazaki ,  Taiji Nishi ,  Motohiro Fukuda ,  Yasuzo Kirita

发明人： Go Tazaki ,  Taiji Nishi ,  Motohiro Fukuda ,  Yasuzo Kirita

IPC分类号： C12M3/00

CPC分类号： C12M25/06 ,  C12M23/10 ,  C12M23/22 ,  C12M23/38 ,  C12M25/14

摘要： It is intended to provide a cell culture chamber in a shape suitable for cell culture. It is also intended to provide a cell culture chamber which is inexpensive and facilitates observation. A cell culture chamber (100) includes a cover (10), a chamber body (20) and a plate-shaped base (30). The cover (10) covers an opening (21) of the chamber body (20). The chamber body (20) contains a culture such as cells. The plate base (30) covers a through hole (24) formed at the bottom (23) of the chamber body (20). Moreover, the plate base (30) has fine pits and projections formed thereon for culturing the culture.

摘要翻译： 旨在提供一种适于细胞培养的形状的细胞培养室。 也是为了提供廉价且便于观察的细胞培养室。 细胞培养室（100）包括盖（10），室主体（20）和板状基部（30）。 盖（10）覆盖室主体（20）的开口（21）。 腔体（20）包含诸如细胞的培养物。 板基座（30）覆盖形成在室主体（20）的底部（23）处的通孔（24）。 此外，板基（30）在其上形成有细微的凹坑和突起，用于培养培养物。

公开(公告)号：US09399340B2

公开(公告)日：2016-07-26

申请号：US14356066

申请日：2012-09-05

申请人： Taiji Nishi

发明人： Taiji Nishi

IPC分类号： B41J2/01 ,  B41J2/005 ,  B41M5/50 ,  B41M5/52

CPC分类号： B41J2/01 ,  B41J2/0057 ,  B41M5/50 ,  B41M5/506 ,  B41M5/508 ,  B41M5/52 ,  B41M5/5209 ,  B41M5/5236 ,  B41M5/5245 ,  B41M5/5254

摘要： The present invention provides a resin-based ink recorded body having high transparency, high definition, free from bleeding and having a high film strength of an ink. An ink recording member of the present invention includes a substrate containing an acrylic resin and a plant oil derived from a fatty acid having hydroxyl and carboxyl group blended to the acrylic resin, and an ink fixing film composed of a hydrophilic resin and provided on at least one main face of the substrate. An ink printed pattern is provided on the film.

摘要翻译： 本发明提供一种树脂系墨水记录体，其具有高透明度，高清晰度，无渗色性，并具有高的油墨强度。 本发明的墨水记录元件包括含有丙烯酸树脂的基材和衍生自与丙烯酸树脂共混的具有羟基和羧基的脂肪酸的植物油，以及由亲水性树脂构成并至少提供至少 衬底的一个主要面。 在薄膜上设置油墨印刷图案。

公开(公告)号：US20160159083A1

公开(公告)日：2016-06-09

申请号：US14356066

申请日：2012-09-05

申请人： Taiji Nishi

发明人： Taiji Nishi

IPC分类号： B41J2/005

CPC分类号： B41J2/01 ,  B41J2/0057 ,  B41M5/50 ,  B41M5/506 ,  B41M5/508 ,  B41M5/52 ,  B41M5/5209 ,  B41M5/5236 ,  B41M5/5245 ,  B41M5/5254

摘要： The present invention provides a resin-based ink recorded body having high transparency, high definition, free from bleeding and having a high film strength of an ink. An ink recording member of the present invention includes a substrate containing an acrylic resin and a plant oil derived from a fatty acid having hydroxyl and carboxyl group blended to the acrylic resin, and an ink fixing film composed of a hydrophilic resin and provided on at least one main face of the substrate. An ink printed pattern is provided on the film.

摘要翻译： 本发明提供一种树脂系墨水记录体，其具有高透明度，高清晰度，无渗色性，并具有高的油墨强度。 本发明的墨水记录元件包括含有丙烯酸树脂的基材和衍生自与丙烯酸树脂共混的具有羟基和羧基的脂肪酸的植物油，以及由亲水性树脂构成并至少提供至少 衬底的一个主要面。 在薄膜上设置油墨印刷图案。