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18 条记录 (耗时 0.021 秒)

    Cell culture container and method of producing the same
    1.
    发明授权
    Cell culture container and method of producing the same 有权
    细胞培养容器及其制备方法

    公开(公告)号：US08435782B2

    公开(公告)日：2013-05-07

    申请号：US12280607

    申请日：2007-02-19

    申请人： Taiji Nishi ,  Go Tazaki ,  Motohiro Fukuda ,  Michio Yazawa ,  Masayuki Takahashi

    发明人： Taiji Nishi ,  Go Tazaki ,  Motohiro Fukuda ,  Michio Yazawa ,  Masayuki Takahashi

    IPC分类号： C12M1/14

    CPC分类号： C12M23/12 ,  B01L3/5085 ,  B01L3/5088 ,  B01L2300/0829 ,  B01L2300/0851 ,  B01L2300/0858 ,  B01L2300/0893 ,  C12M25/00

    摘要： An object of the present invention is to provide a cell culture chamber with which the survival rate of cells to be cultured can be increased, and a method of producing the same. A cell culture chamber according to the present invention includes a mass of projections formed of a plurality of microprojections 1 formed on a surface on which cells are cultured. The width or diameter of each of the microprojections 1 is in a range of 20 nm to 3 μm, and the aspect ratio of each of the microprojections is in a range of 0.2 to 3.0. Thus, there can be provided a cell culture chamber most suitable for the adhesion and differentiation/proliferation of cells to be cultured.

    摘要翻译： 本发明的目的是提供一种能够提高培养细胞存活率的细胞培养室及其制造方法。 根据本发明的细胞培养室包括由在其上培养细胞的表面上形成的多个微突出物1形成的突起体。 每个微喷射体1的宽度或直径在20nm至3μm的范围内，并且每个微喷射体的纵横比在0.2至3.0的范围内。 因此，可以提供最适合于待培养细胞的粘附和分化/增殖的细胞培养室。

    MICROCHANNEL ARRAY AND METHOD FOR PRODUCING THE SAME, AND BLOOD MEASURING METHOD EMPLOYING IT
    2.
    发明申请
    MICROCHANNEL ARRAY AND METHOD FOR PRODUCING THE SAME, AND BLOOD MEASURING METHOD EMPLOYING IT 审中-公开
    MICROCHANNEL ARRAY AND METHOD FOR PRODUCTION THE SAME，和BLOOD MEASURING METHODWORKING IT

    公开(公告)号：US20090149345A1

    公开(公告)日：2009-06-11

    申请号：US11908047

    申请日：2006-03-01

    申请人： Taiji Nishi ,  Motohiro Fukuda ,  Go Tazaki ,  Seiichi Kanai ,  Takenori Kitani ,  Naoto Fukuhara

    发明人： Taiji Nishi ,  Motohiro Fukuda ,  Go Tazaki ,  Seiichi Kanai ,  Takenori Kitani ,  Naoto Fukuhara

    IPC分类号： C40B30/10 ,  C40B40/00 ,  C40B50/00

    CPC分类号： G01N33/80 ,  B01L3/502707 ,  B01L3/502746 ,  B01L2300/0681 ,  B01L2300/0816 ,  G01N33/56972

    摘要： A microchannel array, a method of manufacturing the same, and a blood test method. The microchannel array is formed by joining first and second substrates, each including a fluid inlet and outlet on their surfaces. An internal space structure connects the fluid inlet and outlet, and includes an upstream flow channel connected with the fluid inlet, a downstream flow channel connected with the fluid outlet with a gap therebetween, and a micro flow channel connecting the upstream and downstream flow channels. A minimum distance from a center of a sectional surface of the micro flow channel to a side wall of the micro flow channel is smaller than that of the upstream and downstream flow channels. Each surface of the first and second substrates includes grooves for creating the upstream and downstream flow channels, and the surface of the second substrate has grooves for creating the micro flow channel.

    摘要翻译： 微通道阵列，其制造方法和血液检查方法。 微通道阵列通过接合第一和第二基底而形成，每个基底在其表面上包括流体入口和出口。 内部空间结构连接流体入口和出口，并且包括与流体入口连接的上游流动通道，与流体出口连接的下游流动通道，其间具有间隙，以及连接上游和下游流动通道的微流动通道。 从微流动通道的截面的中心到微流动通道的侧壁的最小距离小于上游和下游流动通道的最小距离。 第一和第二基板的每个表面包括用于产生上游和下游流动通道的槽，并且第二基板的表面具有用于产生微流动通道的凹槽。

    Microchannel array
    4.
    发明授权
    Microchannel array 有权
    微通道阵列

    公开(公告)号：US07432110B2

    公开(公告)日：2008-10-07

    申请号：US11659952

    申请日：2005-08-04

    申请人： Yuji Kikuchi ,  Mitsutoshi Nakajima ,  Taiji Nishi ,  Motohiro Fukuda

    发明人： Yuji Kikuchi ,  Mitsutoshi Nakajima ,  Taiji Nishi ,  Motohiro Fukuda

    IPC分类号： G01N1/18

    CPC分类号： B01L3/502761 ,  B01F3/0807 ,  B01F5/0453 ,  B01F5/0456 ,  B01F13/0059 ,  B01L3/502707 ,  B01L2200/0668 ,  B01L2300/0816 ,  C12M23/16 ,  Y10T436/25375

    摘要： A microchannel array according to the present invention includes a first substrate 1, and a second substrate 11 bonded to the first substrate 1. Two sets, that is, a set of a first through-hole 9, a first recess 7, and a first groove 8 and a set of a second through-hole 4, a second recess 2, and a second groove 3 are formed on the first substrate 1. The different sets are separated by a partition 5. A cell differentation/proliferation speed after micro-injection can be increased by using such microchannel array.

    摘要翻译： 根据本发明的微通道阵列包括第一基板1和结合到第一基板1的第二基板11。 两组，即一组第一通孔9，第一凹槽7和第一凹槽8以及一组第二通孔4，第二凹槽2和第二凹槽3形成在 第一基板1。 不同的集合由分区5分隔。 通过使用这种微通道阵列可以增加微注射后的细胞分化/增殖速度。

    Member for ink recording, ink recording body, and laminated body for ink recording
    5.
    发明授权
    Member for ink recording, ink recording body, and laminated body for ink recording 有权
    油墨记录用构件，油墨记录体和油墨记录层压体

    公开(公告)号：US09399340B2

    公开(公告)日：2016-07-26

    申请号：US14356066

    申请日：2012-09-05

    申请人： Taiji Nishi

    发明人： Taiji Nishi

    IPC分类号： B41J2/01 ,  B41J2/005 ,  B41M5/50 ,  B41M5/52

    CPC分类号： B41J2/01 ,  B41J2/0057 ,  B41M5/50 ,  B41M5/506 ,  B41M5/508 ,  B41M5/52 ,  B41M5/5209 ,  B41M5/5236 ,  B41M5/5245 ,  B41M5/5254

    摘要： The present invention provides a resin-based ink recorded body having high transparency, high definition, free from bleeding and having a high film strength of an ink. An ink recording member of the present invention includes a substrate containing an acrylic resin and a plant oil derived from a fatty acid having hydroxyl and carboxyl group blended to the acrylic resin, and an ink fixing film composed of a hydrophilic resin and provided on at least one main face of the substrate. An ink printed pattern is provided on the film.

    摘要翻译： 本发明提供一种树脂系墨水记录体，其具有高透明度，高清晰度，无渗色性，并具有高的油墨强度。 本发明的墨水记录元件包括含有丙烯酸树脂的基材和衍生自与丙烯酸树脂共混的具有羟基和羧基的脂肪酸的植物油，以及由亲水性树脂构成并至少提供至少 衬底的一个主要面。 在薄膜上设置油墨印刷图案。

    Method of culturing cells under regulation in the extension direction
    6.
    发明授权
    Method of culturing cells under regulation in the extension direction 有权
    在延伸方向调节细胞的方法

    公开(公告)号：US09005970B2

    公开(公告)日：2015-04-14

    申请号：US11813720

    申请日：2006-01-11

    申请人： Ryosuke Nishio ,  Taiji Nishi ,  Motohiro Fukuda ,  Yasuzo Kirita ,  Seiichi Kanai ,  Takenori Kitani

    发明人： Ryosuke Nishio ,  Taiji Nishi ,  Motohiro Fukuda ,  Yasuzo Kirita ,  Seiichi Kanai ,  Takenori Kitani

    IPC分类号： C12M1/12 ,  C12M1/32 ,  C12N5/02 ,  C12M1/22

    CPC分类号： C12M25/06 ,  C12M23/12 ,  C12N5/0657 ,  C12N2533/30 ,  C12N2535/00

    摘要： [PROBLEMS] Relating to a bioassay method with the use of cultured cells and cell culture for a therapeutic purpose in the case of determining the efficacy of a drug or the like or examining the toxicity thereof, it is intended to provide a method of culturing cells under regulation in the extension direction and a cell culture plate. [MEANS FOR SOLVING PROBLEMS] A cell culture plate having a plural number of side walls (1) and a plural number of space structures (3) for providing cultured cells which are formed by the side walls (1), wherein the side walls (1) are provided with openings (2) so that the space structures (3) are linked together. By using this cell culture plate, a method of culturing cells under regulation in the extension direction can be provided.

    摘要翻译： [问题]关于在确定药物等的功效或检查其毒性的情况下使用培养细胞和细胞培养物进行生物测定方法的目的是提供培养细胞的方法 在延伸方向调节和细胞培养板。 解决问题的手段具有多个侧壁（1）和多个用于提供由侧壁（1）形成的培养细胞的多个空间结构（3）的细胞培养板，其中侧壁 1）设置有开口（2），使得空间结构（3）连接在一起。 通过使用该细胞培养板，可以提供在延伸方向的调节下培养细胞的方法。

    CELL CULTURE CONTAINER AND METHOD OF PRODUCING THE SAME
    8.
    发明申请
    CELL CULTURE CONTAINER AND METHOD OF PRODUCING THE SAME 有权
    细胞培养容器及其生产方法

    公开(公告)号：US20090170190A1

    公开(公告)日：2009-07-02

    申请号：US12280607

    申请日：2007-02-19

    申请人： Taiji Nishi ,  Go Tazaki ,  Motohiro Fukuda ,  Michio Yazawa ,  Masayuki Takahashi

    发明人： Taiji Nishi ,  Go Tazaki ,  Motohiro Fukuda ,  Michio Yazawa ,  Masayuki Takahashi

    IPC分类号： C12M1/00 ,  B05D1/32

    CPC分类号： C12M23/12 ,  B01L3/5085 ,  B01L3/5088 ,  B01L2300/0829 ,  B01L2300/0851 ,  B01L2300/0858 ,  B01L2300/0893 ,  C12M25/00

    摘要： An object of the present invention is to provide a cell culture chamber with which the survival rate of cells to be cultured can be increased, and a method of producing the same. A cell culture chamber according to the present invention includes a mass of projections formed of a plurality of microprojections 1 formed on a surface on which cells are cultured. The width or diameter of each of the microprojections 1 is in a range of 20 nm to 3 μm, and the aspect ratio of each of the microprojections is in a range of 0.2 to 3.0. Thus, there can be provided a cell culture chamber most suitable for the adhesion and differentiation/proliferation of cells to be cultured.

    摘要翻译： 本发明的目的是提供一种能够提高培养细胞存活率的细胞培养室及其制造方法。 根据本发明的细胞培养室包括由在其上培养细胞的表面上形成的多个微突出物1形成的突起体。 每个微喷射体1的宽度或直径在20nm至3μm的范围内，并且每个微喷射体的纵横比在0.2至3.0的范围内。 因此，可以提供最适合于待培养细胞的粘附和分化/增殖的细胞培养室。

    CELL CULTURE CONTAINER AND METHOD OF PRODUCING THE SAME
    9.
    发明申请
    CELL CULTURE CONTAINER AND METHOD OF PRODUCING THE SAME 有权
    细胞培养容器及其生产方法

    公开(公告)号：US20090075363A1

    公开(公告)日：2009-03-19

    申请号：US12298803

    申请日：2007-04-25

    申请人： Yuji Morimoto ,  Taiji Nishi ,  Taisuke Kamada ,  Go Tazaki ,  Motohiro Fukuda

    发明人： Yuji Morimoto ,  Taiji Nishi ,  Taisuke Kamada ,  Go Tazaki ,  Motohiro Fukuda

    IPC分类号： C12M3/00 ,  B05D5/10

    CPC分类号： C12M23/12 ,  C12M23/16

    摘要： To provide a cell culture chamber capable of reproducing a cell function in vivo, and a method of producing the same. The cell culture chamber according to the present invention has a concave-convex pattern formed on the surface on which cells are cultured. A concave portion of the concave-convex pattern includes cell culture portions and micro flow channels communicating with the cell culture portions. The bottom surface of each of the cell culture portions has a width 1.0 to 20 times an equivalent diameter of each of the cultured cells. A cell adhesion-inducing substance is formed only on the bottom surface and the side walls of the concave portion.

    摘要翻译： 提供能够在体内再现细胞功能的细胞培养室及其制造方法。 根据本发明的细胞培养室具有形成在其上培养细胞的表面上的凹凸图案。 凹凸图案的凹部包括与细胞培养部连通的细胞培养部和微流路。 每个细胞培养部分的底表面具有每个培养细胞的当量直径的1.0至20倍的宽度。 细胞粘附诱导物质仅形成在凹部的底面和侧壁上。