摘要:
The present invention provides a method of diagnosing the presence or severity of liver fibrosis in an individual by detecting α2-macroglobulin (α2-MG) in sample from the individual; detecting hyaluronic acid (HA) in a sample from the individual; detecting tissue inhibitor of a metalloproteinases-1 (TIMP-1) in a sample from the individual; and diagnosing the presence or severity of liver fibrosis in the individual based on the presence or level of α-MG, HA and TIMP-1.
摘要:
The present invention provides a method of diagnosing the presence or severity of liver fibrosis in an individual by detecting α2-macroglobulin (α2-MG) in a sample from the individual; detecting hyaluronic acid (HA) in a sample from the individual; detecting tissue inhibitor of metalloproteinases-1 (TIMP-1) in a sample from the individual; and diagnosing the presence or severity of liver fibrosis in the individual based on the presence or level of α2-MG, HA and TIMP-1.
摘要:
A method of judging a biological state comprising using: (1) correlation and/or symmetry between Lyapunov exponent and entropy; and/or (2) Higuchi fractal dimension, wherein the Lyapunov exponent, entropy and Higuchi fractal dimension are indices that can express chaotic nature and derived from time series data of biological signals from a subject.
摘要:
A method and system for the analysis of biological, medical and/or biochemical data having values for each of a plurality of attributes, having a receiving portion for receiving the data and entering it into a storage arrangement like a relational database in accordance with the values and attributes of the data; a calculating portion for determining discrete bins for at least one of the attributes for the data in accordance with the values of the data entered in the storage arrangement; a re-organizing portion for re-organizing the data in the storage arrangement in accordance with the discrete bins; a data mining portion for mining the organized data in the storage arrangement to determine sets of applicable logical rules; and a processing and presenting portion for logical rules or groups of logical rules. The processing portion further involves the application of at least one operator to create a subset of rules in an iterative manner. The operators are filtering operators, clustering operators, data mapping operators, and/or data characterization operators.
摘要:
The present invention provides a method of diagnosing the presence or severity of liver fibrosis in an individual by detecting null2-macroglobulin (null2-MG) in a sample from the individual; detecting hyaluronic acid (HA) in a sample from the individual; detecting tissue inhibitor of metalloproteinases-1 (TIMP-1) in a sample from the individual; and diagnosing the presence or severity of liver fibrosis in the individual based on the presence or level of null2-MG, HA and TIMP-1.
摘要:
An automated, real-time, reprogrammable monitoring and control system for portable, remote sensors and subjects includes one or more portable monitoring units, each of the portable monitoring units having a sensor, a location-determining device, and a sensor interface unit. Each sensor interface unit is separately configured to monitor its sensor and to transmit that sensor's data, via a digital wireless communications network, to a central monitoring device. The portable unit is carried or worn by a person or animal, or affixed to an inanimate subject.
摘要:
Apparatus and methods are disclosed for generating individualized medical profiles based on information provided by a patient, and on data extracted from medical literature. In a first stage, medical literature is selected for inclusion in a database by using specified inclusion criteria. Information on input parameters to studies contained in the literature, output parameters of the studies, and algorithms contained in the studies is extracted from the literature, and stored in a database. In a second stage, patients provide information, which is matched against the input parameters of the studies in the database, and algorithms from the matched studies are applied to the information provided by the patient to produce values for the output parameters. Combination analysis is used to combine the values of output parameters into “super-category” values, that are used to generate an individualized medical profile.
摘要:
The present invention provides a system, method and apparatus for obtaining status information from a portable medical device and communicating said status information to a remote system or user. In one embodiment, the system comprises a sensing device that comprises an optical receiver for receiving status information from at least one status indicator of the portable medical device. The optical receiver is positioned in sufficient proximity to the status indicator to allow optical communication between the optical receiver and the status indicator. A circuit couplable to the optical receiver communicates the status information represented by the status indicator to the remote system or user. In another embodiment, the sensing device comprises a microphone to receive audible status signals from the portable medical device. In yet another embodiment, the sensing device is mounted to a housing, which allows sensing device to sense the status information of an enclosed portable medical device.
摘要:
A graphical user interface for a medical instruments for a Renal Replacement Therapy is disclosed that includes a pictogram representation of the fluid path of an extracorporeal blood circuit that represents fluid lines, pumps and sensors. To assist the user in responding to alarms and rectifying faults in the system the source of a potential trouble is animated. The location of a trouble spot is easily identified by flashing of the corresponding element of the pictogram, change of color or thickness of a corresponding line.
摘要:
Systems and methods using a spectrometer system for real-time automatic evaluation of tissue injury are described. A method of assessing an injury to tissue comprises reflecting an electromagnetic signal from the tissue to produce a reflected electromagnetic signal; producing spectral data pertaining to the intensities of individual wavelengths of the reflected electromagnetic signal; analyzing the spectral data to obtain a set of results; and providing an indication of the nature of the injury to the tissue based upon the set of results.