公开(公告)号：US3634868A

公开(公告)日：1972-01-11

申请号：US3634868D

申请日：1970-03-13

申请人： TECHNICON INSTR

发明人： PELAVIN MILTON H ,  KOSZYN ALLAN I ,  HEIER EARL

IPC分类号： G01N21/27 ,  G01N35/08 ,  G01N21/20

CPC分类号： G01N21/274 ,  G01N35/08 ,  G01N2201/12723

摘要： New and improved method and apparatus for automatic, periodic baseline and standard calibration of analysis results recording means which record the results of sample analyses performed by multichannel sample analysis means in accordance with the output of the latter are provided to compensate for drift in said analysis means output, and comprise the conditioning of said sample analysis means and the adjustment of said output to a desired value for baseline calibration for each of said channels, the conditioning of said sample analysis means and the adjustment of said output to a desired value for standard calibration for each of said channels, the comparison of said output with said desired value thereof for baseline calibration for each of said channels and, if drift has occurred, the generation of information to drive said output to said desired value for baseline calibration, the comparison of said output with said desired value thereof for standard calibration for each of said channels and, if drift has occurred, the generation of information to drive said output to said desired value thereof for standard calibration, the storing of said baseline and standard calibration information for each of said channels for repeated reuse in sequence with channel changes during sample analysis operation of said sample analysis means, and the updating of said standard and baseline calibration information for each of said channels by the standard and baseline calibration information generated during subsequent operation of said calibration apparatus.

摘要翻译： 提供新的和改进的用于分析结果的自动，周期性基线和标准校准的方法和装置，记录装置，其记录根据后者的输出的多通道样本分析装置进行的样本分析结果，以补偿所述分析装置中的漂移 输出，并且包括对所述样本分析装置的调节和将所述输出调节到用于每个所述通道的基线校准的期望值，所述样本分析装置的调节和所述输出的调节为用于标准校准的期望值 对于每个所述通道，将所述输出与所述期望值的比较用于每个所述通道的基线校准，并且如果发生漂移，则产生用于将所述输出驱动到所述基准校准所需值的信息， 所述输出具有所述期望值，用于每个所述cha的标准校准 并且如果发生漂移，则产生用于将所述输出驱动到所述期望值的信息以用于标准校准，存储所述基准线和每个所述信道的标准校准信息，以便在样本分析期间按顺序重新使用信道变化 所述样本分析装置的操作，以及通过在所述校准装置的后续操作期间产生的标准和基线校准信息来更新每个所述通道的所述标准和基线校准信息。

公开(公告)号：US3511607A

公开(公告)日：1970-05-12

申请号：US3511607D

申请日：1967-10-06

申请人： SMITHKLINE CORP

发明人： GREEN STANLEY E

IPC分类号： G01N33/72 ,  G01N21/20 ,  G01N31/22

CPC分类号： G01N33/728 ,  Y10S436/903 ,  Y10T436/146666

公开(公告)号：US3464257A

公开(公告)日：1969-09-02

申请号：US3464257D

申请日：1967-02-14

申请人： LIST HANS

发明人： SCHREIBER ERICH ,  SKATSCHE OTHMAR

IPC分类号： G01N15/06 ,  G01N21/86 ,  G01N1/22 ,  G01N21/20

CPC分类号： G01N15/0618 ,  G01N21/86

公开(公告)号：US6106778A

公开(公告)日：2000-08-22

申请号：US161127

申请日：1998-09-25

申请人： Narihiro Oku ,  Yasuo Yamao

发明人： Narihiro Oku ,  Yasuo Yamao

IPC分类号： G01N15/00 ,  G01N15/10 ,  G01N35/10 ,  G01N25/20 ,  B01J19/08 ,  G01N33/48 ,  G05B1/00 ,  G01N21/20

CPC分类号： G01N15/10 ,  G01N2015/0065 ,  G01N2015/1006 ,  G01N2035/1032 ,  G01N35/10 ,  Y10S436/805 ,  Y10T436/11 ,  Y10T436/25 ,  Y10T436/25125 ,  Y10T436/25625 ,  Y10T436/2575

摘要： A compact combination blood cell count and immunoassay apparatus for measuring drawn whole blood specimen includes a load station for receiving the whole blood specimen and a nozzle member that can selectively withdraw whole blood from the blood specimen. A blood cell count section and an immunoassay section are mounted along a unitary path of movement of the nozzle member so that a single nozzle member may be used for transporting the whole blood to the respective blood cell count section and immunoassay section. A controller can automatically direct a transport mechanism to use only the whole blood and to perform various steps of adding dilution liquid and reagents, along with appropriate washing of the nozzle and sample cells to insure an automatic operation. A hematozorit value can be determined from the blood cell count signal and used to correct the immunoassay signal when whole blood is used.

摘要翻译： 用于测量全血标本的紧凑的组合型血细胞计数和免疫测定装置包括用于接收全血样本的装载站和能够选择性地从血液样本中取出全血的喷嘴构件。 沿着喷嘴构件的整体运动路径安装血细胞计数部分和免疫测定部分，使得可以使用单个喷嘴构件将全血传输到各个血细胞计数部分和免疫测定部分。 控制器可以自动引导运输机构仅使用全血，并执行添加稀释液和试剂的各种步骤，以及适当地洗涤喷嘴和样品池以确保自动操作。 可以从血细胞计数信号确定血液浓度值，并且当使用全血时用于校正免疫测定信号。

公开(公告)号：US4039284A

公开(公告)日：1977-08-02

申请号：US713991

申请日：1976-08-12

申请人： Thomas P. Mancini

发明人： Thomas P. Mancini

IPC分类号： G01N31/22 ,  G01N33/18 ,  G01N21/20

CPC分类号： G01N33/182 ,  G01N31/22 ,  Y10T436/147777

摘要： A formulation for colorimetric determination of the concentration of cyanuric acid compounds, particularly in swimming pool water, comprises an aqueous solution of a stabilizer, monoethanolamine and a thymolsulfonphthalein compound which, in aqueous solution with monoethanolamine, will exhibit different characteristic color shades dependent upon the concentration of cyanuric acid compounds. The stabilizer is a water-soluble, ultraviolet light absorbing material which is a condensation product of a disulfonic acid derivative with stilbene, stilbyle or their derivatives.A method of testing for cyanuric acid compound concentrations is to mix the formulation with a sample of swimming pool water and compare the resultant characteristic color shade with a standard color shade.

摘要翻译： 用于比色测定氰尿酸化合物，特别是游泳池水中的浓度的配方包括稳定剂水溶液，单乙醇胺和甲酚磺酞化合物，其在单乙醇胺的水溶液中将会根据浓度显示出不同的特征色调 的氰尿酸化合物。 稳定剂是一种水溶性的紫外光吸收材料，它是二磺酸衍生物与芪，芪或其衍生物的缩合产物。

公开(公告)号：US3907503A

公开(公告)日：1975-09-23

申请号：US43500174

申请日：1974-01-21

申请人： MILES LAB

发明人： BETTS CLEO ELMER ,  MARSH JOHN KENDALL

IPC分类号： G01N33/48 ,  G01N21/78 ,  G01N31/22 ,  G01N35/00 ,  G01N35/10 ,  G01N21/06 ,  G01N21/20 ,  G01N21/28

CPC分类号： G01N35/00594 ,  G01N21/8483 ,  G01N35/00029 ,  G01N35/00693 ,  G01N35/00732 ,  G01N2035/00039 ,  G01N2035/00118 ,  G01N2035/00772 ,  G01N2035/1025

摘要： A test system for the semi-automatic analysis of chemical constituents in a test fluid which comprises test devices having test reagents and code means associated therewith and an instrument which receives the test devices and is programmed by the device code means for automatically reading the particular test reagents associated with the particular test device being used. Preferably the test reagents are in a dry form, immobilized in or on a carrier member which upon contact with the test fluid can be manually presented to the instrument. Another preferable embodiment of the present device comprises the use of the code means to calibrate the instrument each time a test device is introduced thereto.

摘要翻译： 用于半自动分析测试流体中的化学成分的测试系统，其包括具有测试试剂和与其相关联的代码装置的测试装置，以及接收测试装置并由设备代码装置编程的仪器，用于自动读取特定测试 与正在使用的特定测试装置相关联的试剂。 优选地，测试试剂为干燥形式，固定在承载构件中或载体构件上，其与测试流体接触可以手动提供给仪器。 本装置的另一优选实施例包括使用代码装置来在每次将测试装置引入时对仪器进行校准。

公开(公告)号：US3764267A

公开(公告)日：1973-10-09

申请号：US3764267D

申请日：1971-09-14

申请人： FARR DEVICES INC

发明人： FARR A

IPC分类号： B01L99/00 ,  G01N35/00 ,  G01N33/16 ,  G01N21/20

CPC分类号： G01N35/00 ,  B01L3/0293

摘要： A COMPACT INSTRUMENT FOR MEASURING THE HEMOGLOBIN CONTENT OF WHOLE BLOOD, PARTICULARLY ARRANGED FOR THE RAPID ANALYSIS OF A MINUTE SAMPLE OF A PATIENT''S BLOOD SUPPLIED IMMEDIATELY AFTER COLLECTION, BY A DOCTOR IN HIS OWN OFFICE. THE INSTRUMENT IS SO ARRANGED THAT IT MAY BE FULLY AUTOMATED, TO MAKE THE HEMOGLOBIN DETERMINATION AFTER A BLOOD SAMPLE HAS BEEN DELIVERED TO IT, AND TO PROVIDE AN ANALYSIS FOR THE DOCTOR''S USE WITHIN A FEW MINUTES. THE INSTRUMENT UTILIZES A PUMP WHICH DELIVERES TO AND MIXES WITH THE BLOOD SAMPLE IN A PHOTOMETER EXAMINATION CELL, AN ACCURATELY AND CONTINUOUSLY MEASURED AMOUNT OF AN AQUEOUS REAGENT, UNTIL THE VOLUME OF REAGENT ADDED CAUSES THE SAMPLE TO MATCH PHOTOMETRICALLY A STRANDED SAMPLE. THE HEMOGLOBIN CONTENT IS DIRECTLY SHOWN IN APPROPRIATE UNITS ON A METER OR READOUT DEVICES AT THE COMPLETION OF A CYCLE. IN THE FULLY AUTOMATED FORM OF THE DEVICE, A COMPLETE ANALYSIS CYCLE LEAVES THE INSTURMENT CLEANED OUT AND READY TO MAKE ANOTHER ANALYSIS UPON RECEPTION OF ANOTHER BLOOD SAMPLE.

公开(公告)号：US3669543A

公开(公告)日：1972-06-13

申请号：US3669543D

申请日：1970-02-06

申请人： COLUMBIA CONTROLS RESEARCH COR

发明人： VACCARO ANGELO

IPC分类号： G01N21/27 ,  G01N21/20 ,  G01N21/48 ,  G01N33/16

CPC分类号： G01N21/274

摘要： A METHOD AND APPARATUS FOR STANDARDIZING TWO DENSITOMETERS TO HAVE THE SAME READING FOR SAMPLES HAVING THE SAME OPTICAL DENSITY EVEN THOUGH BOTH DENSITOMETERS ARE NOT IDENTICALLY CALIBRATED BY READING THE SAMPLE WITH ONE DENSITOMETER AND NOTING ITS DENSITY. AN OPAQUE SCREEN HAVING AN APERTURE IS THEN POSITIONED BEFORE THE LIGHT ENTRANCE OF THE DENSITOMETER WITH THE SIZE OF THE APERTURE BEING ADJUSTED TO PRODUCE THE SAME DENSITOMETER READING AS THE SAMPLE. AN APAQUE SCREEN HAVING THE SAME SIZE OPENING IS THEN PLACED BEFORE THE LIGHT ENTRANCE OF THE SECOND DENSITOMETER AND THIS SECOND DENSITOMETER IS ADJUSTED TO HAVE THE SAME REFLECTIVITY READING AS THE FIRST DENSITOMETER. A SAMPLE ACCORDINGLY HAVING THE SAME OPTICAL DENSITY WILL BE READ IDENTICALLY BY BOTH METERS. ALSO, THE OPENINGS, ACCURATELY SIZED FOR DESIRED DENSITY READINGS MAY BE USED FOR CALIBRATING A DENSITOMETER.

公开(公告)号：US3591805A

公开(公告)日：1971-07-06

申请号：US3591805D

申请日：1969-02-20

申请人： SCHOEFFEL INSTRUMENT CORP

发明人： SCHOEFFEL DIETMAR M

IPC分类号： G01N30/92 ,  G01N21/20

CPC分类号： G01N30/92

摘要： A chromatographic plate wherein the spectral transmission is preadjusted and which is provided with preadjusted transparent and opaque intervals.

公开(公告)号：US3552926A

公开(公告)日：1971-01-05

申请号：US3552926D

申请日：1968-12-10

申请人： US NAVY

发明人： FAUTH MAE I ,  RICHARDSON ANNIE C

IPC分类号： G01N31/22 ,  G01N21/20

CPC分类号： G01N31/22 ,  Y10T436/173076

摘要： A CONTINUOUS METHOD FOR DETERMINING THE STABILITY OF NITROGLYCERIN BY DETECTING THE PRESENCE OF NITRITE ION THROUGH A COLOR TEST WHICH CONSISTS OF ADDING TO THE NITRATE ESTER A COLOR PRODUCING REAGENT SUCH AS A GRIESS TYPE REAGENT, CONTAINING (1) SULFANILIC ACID, AND (2) 1-NAPHTHYLAMINE, 1-NAPHTHYLAMINE OXALATE OR N-(1-NAPTHYL)ETHYLENEDIAMINE DIHYDROCHLORIDE AND DETECTING THE COLOR CHANGE.