公开(公告)号：US12060584B2

公开(公告)日：2024-08-13

申请号：US18469527

申请日：2023-09-18

Applicant: YONGNONG BIOSCIENCES CO., LTD. ,  EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY ,  NINGXIA YONGNONG BIOSCIENCES CO., LTD.

Inventor： Dongzhi Wei ,  Hualei Wang ,  Chengjun Wu ,  Qinghai Liu ,  Jian Zhang ,  Zhonghua Luo ,  Changlei Zhang

IPC: C12N9/06 ,  C12N9/08 ,  C12N15/70 ,  C12P13/04

CPC classification number: C12N9/0024 ,  C12N9/0065 ,  C12N15/70 ,  C12P13/04 ,  C12Y104/01005 ,  C12Y111/01006

Abstract: Embodiments of the present disclosure relate to a D-amino acid oxidase mutant and application in preparing L-glufosinate thereof. The D-amino acid oxidase mutant has an amino acid substitution at at least one of position 62 and position 226 of an amino acid sequence of the D-amino acid oxidase mutant when compared to an amino acid sequence of a D-amino acid oxidase as set forth in SEQ ID NO. 1, the position 62 and position 226 being defined with reference to SEQ ID NO. 1, and the amino acid sequence of the D-amino acid oxidase mutant having at least 90% identity to SEQ ID NO. 1.

公开(公告)号：US20240191082A1

公开(公告)日：2024-06-13

申请号：US18286457

申请日：2022-04-02

Applicant: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY ,  SHANGHAI JIAO TONG UNIVERSITY ,  CHINA UNITED GAS TURBINE TECHNOLOGY CO., LTD.

Inventor： Xiancheng Zhang ,  Xiaofeng Zhao ,  Yali Yu ,  Shantung Tu ,  Dingwu Zhang ,  Xiaobo Wang ,  Junmiao Shi ,  Weize Wang

IPC: C09D1/00 ,  C23C4/02 ,  C23C4/06 ,  C23C4/11 ,  C23C4/134

CPC classification number: C09D1/00 ,  C23C4/02 ,  C23C4/06 ,  C23C4/11 ,  C23C4/134

Abstract: Provided are a thermal barrier coating and a preparation method thereof, which belong to the field of coating technology. The thermal barrier coating has a double-layer coating structure, and includes an intermediate layer attached to a surface of a metal bonding layer, and a top layer, wherein the intermediate layer is formed by atmospheric plasma spraying YSZ porous microspheres, and the top layer is formed by atmospheric plasma spraying Yb—Gd codoped YSZ porous microspheres; the intermediate layer is in contact with the surface of the metal bonding layer, and the top layer is directly exposed to a high-temperature gas environment

公开(公告)号：US20240157326A1

公开(公告)日：2024-05-16

申请号：US18176470

申请日：2023-02-28

Applicant: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY

Inventor： Yuan Zong ,  Gance Dai ,  Long He ,  Hanguang Xie

IPC: B01J19/32

CPC classification number: B01J19/32 ,  B01J2219/32244 ,  B01J2219/3306

Abstract: The present disclosure belongs to the technical field of packings, and in particular, to a packing element, a structured packing and an application of the structured packing. The packing element includes a collection-predistribution unit, a fluid uniform distribution unit, and an opening window unit that are sequentially arranged. The fluid uniform distribution unit includes a first substrate and a plurality of orifices arranged on the first substrate. Each orifice is circular and/or semicircular. Each orifice has an equivalent diameter of 1-5 mm. The opening window unit is provided with a plurality of windows, and each window has a length proportional to 0.5 power of the fluid viscosity. Fluid forms a confined free film in the window region of the opening window unit and wall-bounded film on the wall surface region.

公开(公告)号：US11965070B2

公开(公告)日：2024-04-23

申请号：US17453102

申请日：2021-11-01

Applicant: East China University of Science and Technology

Inventor： Qixin Zhuang ,  Zhe Zhang ,  Xiaoyun Liu ,  Jian Xu ,  Wentao Wang ,  Zeyang Wu ,  Xiaohan Wu ,  Lihui Li

IPC: C08J5/18 ,  C01B33/148 ,  C08K3/36 ,  C08K7/18 ,  C08K7/26 ,  C08K9/04 ,  C08L79/04

CPC classification number: C08J5/18 ,  C01B33/148 ,  C08K7/26 ,  C08L79/04 ,  C01P2004/34 ,  C01P2006/16 ,  C08J2339/00 ,  C08J2379/04 ,  C08K3/36 ,  C08K7/18 ,  C08K9/04

Abstract: The disclosure relates to the field of electronic materials, and in particular to a composite film of fluorinated polybenzoxazole (6FPBO) and triple-shelled mesoporous silica hollow spheres, and to its preparation and use. The composite film comprises fluorinated polybenzoxazole as a matrix and amino-functionalized triple-shelled mesoporous silica hollow spheres which are dispersed in the fluorinated polybenzoxazole matrix. A mass ratio of (amino-functionalized triple-shelled mesoporous silica hollow spheres)/(fluorinated polybenzoxazole) is 1/100 to 5/100. The composite film has excellent thermal stability and a lower dielectric constant.

公开(公告)号：US11963453B1

公开(公告)日：2024-04-16

申请号：US18454097

申请日：2023-08-23

Applicant: East China University of Science and Technology ,  Ningbo University

Inventor： Haiping Fang ,  Liang Chen ,  Chaofeng Lv

IPC: H01L41/113 ,  G01L1/16 ,  H10N30/30 ,  H10N30/853 ,  H10N30/88

CPC classification number: H10N30/8542 ,  G01L1/16 ,  H10N30/302 ,  H10N30/308 ,  H10N30/88

Abstract: A piezoelectric sensor is provided. The piezoelectric sensor comprises a first base, a first conductive layer adjacent to the first base, a second base, a second conductive layer adjacent to the second base; and a first structure between the first conductive layer and the second conductive layer. The first structure comprises a first layer with a first carbon-based material and a plurality of second structures with piezoelectricity. Each of the plurality of second structures comprises a second layer with a second carbon-based material and a third layer adjacent to the second layer. The third layer comprises a material of two-dimensional crystals of unconventional stoichiometries such as Na2Cl crystals.

公开(公告)号：US20240058773A1

公开(公告)日：2024-02-22

申请号：US18260176

申请日：2021-03-25

Applicant: East China University of Science and Technology

Inventor： Hao LU ,  Qiang YANG ,  Yudong LI ,  Yiqian LIU ,  Pinyi DAI ,  Shihan WU

IPC: B01F23/41 ,  B01F23/451 ,  B01F25/20 ,  B01F25/21 ,  B01F25/10 ,  B01F25/4314 ,  B01F25/433

CPC classification number: B01F23/4105 ,  B01F23/4143 ,  B01F23/451 ,  B01F25/28 ,  B01F25/211 ,  B01F25/103 ,  B01F25/43141 ,  B01F25/4334 ,  B01F2025/916

Abstract: The invention provides a device for enhancing liquid-liquid emulsification. The device includes a jet part and a mixing part connected to the jet part. The jet part includes a feed tee for feeding major and dispersed phases, wherein the feed tee includes a first port, a second port, and a third port. The first port is used for feeding the major phase, and the second port is equipped with an ejector for feeding the dispersed phase. The ejector consists of an ejector housing and an ejector inlet section, as well as a spiral structure, a flow-guided structure, and an ejector pin structure that are connected sequentially. The mixing part includes a mixer comprising a cylindrical mixer shell, a mixer inlet section, a mixer outlet section, as well as a spiral section, a cavity section, and a variable diameter section for enhancing emulsion breakup and dispersion. A method for enhancing liquid-liquid emulsification is also disclosed. The emulsion produced by the device and method of the invention is uniformly dispersed, has long stability, and the device has a compact structure and low energy consumption. It is particularly suitable for liquid-liquid emulsification processes in fields such as chemical industry, food, coatings, and cosmetics.

公开(公告)号：US11904423B2

公开(公告)日：2024-02-20

申请号：US17764136

申请日：2020-05-20

Applicant: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY

Inventor： Xiancheng Zhang ,  Kaiming Zhang ,  Shulei Yao ,  Shuang Liu ,  Feng Cheng ,  Shantung Tu

IPC: B23P9/02

CPC classification number: B23P9/02

Abstract: Provided is a bilateral ultrasonic rolling processing track coordination method for a blade surface, the method comprising: step S1, performing layering processing on a blade to acquire a contour curve of “A”-shaped and “n”-shaped blade edges of a blade model at different heights; step S2: determining the endpoints of a blade processing track; and step S3: planning the thickness and the rotation angle of the blade, comprising: step S31, solving a main direction angle αmain of the contour curve; step S32, solving the thickness d of the blade; step S33, solving a rotation angle required by blade processing when the blade edge is “A”-shaped; and step S34, solving the rotation angle required by blade processing when the blade edge is “n”-shaped. According to the method, blade deformation generated by an ultrasonic rolling force is reduced, the processing efficiency is improved, and the blade processing precision is also improved.

公开(公告)号：US20240027344A1

公开(公告)日：2024-01-25

申请号：US16981088

申请日：2019-03-15

Applicant: East China University of Science and Technology

Inventor： Yi Yang ,  Yuzheng Zhao ,  Xie Li ,  Yejun Zou ,  Changcheng Zhang

IPC: G01N21/64

CPC classification number: G01N21/6428

Abstract: The disclosure provides a fluorescent sensor, comprising a) a responsive polypeptide, and b) an optically active polypeptide, wherein the optically active polypeptide is inserted into the responsive polypeptide. The present disclosure also relates to a nucleic acid sequence encoding the fluorescent sensor according to any embodiment, or a complementary sequence thereof. The disclosure also provides an expression vector comprising the nucleic acid sequence or a complementary sequence thereof of the disclosure operably linked to an expression control sequence. The disclosure also provides a cell containing the expression vector of the disclosure. The present disclosure also provides a method for preparing the fluorescent sensor of this disclosure, comprising the following steps: providing a host cell comprising an expression vector that expresses the fluorescent sensor of the disclosure, culturing the host cell under conditions suitable for the expression of the host cell, and separating the fluorescent sensor. The disclosure also provides uses of the fluorescent sensor described in the disclosure or the fluorescent sensor prepared according to the method of the disclosure in detecting BCAAs. In one embodiment, the branched chain amino acids are selected from leucine, isoleucine and valine. The detection can be conducted in vitro, in vivo, in situ, or at subcellular level. The disclosure also provides a kit, comprising the fluorescent sensor described in the disclosure or the fluorescent sensor prepared according to the method of the disclosure.

公开(公告)号：US20230314273A1

公开(公告)日：2023-10-05

申请号：US18021173

申请日：2022-08-04

Applicant: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY

Inventor： Xiancheng ZHANG ,  Liqiang LIU ,  Jianping TAN ,  Runzi WANG ,  Shantung TU ,  Junmiao SHI

IPC: G01M9/04 ,  G01N3/56

CPC classification number: G01M9/04 ,  G01N3/56

Abstract: An ultrahigh-temperature wind tunnel erosion testing system is provided, including a fuel system (1), an erosion system (2), an erosion spray gun (3), a test piece fixture (5) and a testing device; the erosion spray gun (3) is connected with the fuel system (1) and the erosion system (2) respectively; the erosion spray gun (3) is arranged on a lifting and rotating mechanism (4); the test piece fixture (5) is arranged on one side of the lifting and rotating mechanism (4) and is opposite to a nozzle of the erosion spray gun (3); and the testing device is connected with the test piece fixture (5). The plurality of groups of test pieces are circlewise arranged around the lifting and rotating mechanism (4).

公开(公告)号：US20230091503A1

公开(公告)日：2023-03-23

申请号：US17990038

申请日：2022-11-18

Applicant: East China University of Science and Technology

Inventor： Changsheng Liu ,  Hongyan He ,  Lili Jin ,  Dian Zhang

IPC: A61M37/00 ,  B29C33/38

Abstract: The present invention relates to a preparation method for a microneedle patch. Specifically, the present invention provides a preparation method for a microneedle patch, and the method comprises steps: (1) milling a base into a master mold of the microneedle patch; (2) conducting surface treatment on the master mold, to obtain the treated master mold; (3) conducting reverse molding on a surface of the treated master mold, conducting deaeration, curing, and demolding, to obtain the cured daughter mold; and (4) casting the modification solution on the surface of the daughter mold, and then conducting deaeration, drying and curing, to obtain the microneedle patch. The method for preparing the microneedle patch in the present invention can greatly reduce the milling difficulty, and save the milling cost and time. The microneedle molds with different aspect ratios, areas and shapes can also be prepared as required, following with reverse molding to diverse microneedle patches. Therefore, a feasible implementation scheme is provided in present invention for the production application of the microneedles and the feasibility of the wide application is greatly enhanced.