Spatial-domain low-coherence quantitative phase microscopy

    公开(公告)号:US11105686B2

    公开(公告)日:2021-08-31

    申请号:US13695230

    申请日:2011-05-09

    Abstract: Due to potential sampling errors (due to small tissue samples not necessarily directly from the developing tumor) and limited optical resolution (˜1 micron), cancer may be missed or detected too late for optimal treatment, or conservative interpretation of indeterminate findings could lead to unnecessary surgery. The novel technology herein—Spatial-domain Low-coherence Quantitative Phase Microscopy (SL-QPM)—can detect structural alterations within cell nuclei with nanoscale sensitivity (0.9 nm) (or nuclear nano-morphology) for “nano-pathological diagnosis” of cancer. SL-QPM uses original, unmodified cytology and histology specimens prepared with standard clinical protocols and stains. SL-QPM can easily integrate in existing clinical pathology laboratories. Results quantified the spatial distribution of optical path length or refractive index in individual nuclei with nanoscale sensitivity, which could be applied to studying nuclear nano-morphology as cancer progresses. The nuclear nano-morphology derived from SL-QPM offers significant diagnostic value in clinical care and subcellular mechanistic insights for basic and translational research.

    Process for making biofuel from spent coffee grounds

    公开(公告)号:US11066616B1

    公开(公告)日:2021-07-20

    申请号:US16897620

    申请日:2020-06-10

    Abstract: A system and process for producing biofuel from spent coffee grounds (SCGs) comprises the steps of performing a first operation comprising the steps of obtaining spent SCGs from a source, washing the SCGs, mixing the washed SCGs with an inorganic acid and heating and stirring the washed SCGs to form a SCG slurry without separating coffee oil, drying the SCG slurry, mixing the dried slurry with a solvent and heating the dried slurry and solvent mixture to create a reaction to produce biofuel and residual grounds, and separating the biofuel from the solvent and the residual grounds. The process further includes the step of using an activation agent and heating the residual grounds and the activation agent to create activated residual grounds. Biochar is also produced without activation and heating de-oiled SCGs at lower temperatures without oxygen.

    MULTIPURPOSE IMAGING AND DISPLAY SYSTEM
    203.
    发明申请

    公开(公告)号:US20200053298A1

    公开(公告)日:2020-02-13

    申请号:US16599850

    申请日:2019-10-11

    Applicant: Yang Liu

    Inventor: Yang Liu

    Abstract: A multi-purpose imaging and display system includes a display; a detector coupled to the display and having a field of view; and a filter communicating with the detector. The field of view is imaged by the detector through the filter, the filter configured to be sensitive to a first frequency spectrum, so the detector displays only objects within the field of view on the detector that emit one or more frequencies within the first frequency spectrum. The detector and filter can work together in different operational states or modes for acquiring image data of a target object under investigation. A computing device can be included to process acquired image data, and communication interfaces can be employed to achieve networking of multiple systems. A peripheral interface allows a plurality of peripheral devices to be selectively added to tailor the data acquisition and display capabilities of the imaging and display system.

    Selectably opaque displays
    206.
    发明申请

    公开(公告)号:US20180088323A1

    公开(公告)日:2018-03-29

    申请号:US15732157

    申请日:2017-09-25

    Applicant: Sheng Bao Yang Liu

    Inventor: Sheng Bao Yang Liu

    Abstract: Devices are often presented with displays that are selectively designed for a particular presentation type, such as virtual reality environments, head-mounted displays, and heads-up displays. However, display design choices that promote one presentation type may diminish the usability of the device for other presentation type, requiring users to utilize multiple devices with specialized displays. Instead, a display of a device may exhibit an opacity that is selectable between a substantially opaque state and a substantially transparent state, optionally with one or more semi-opaque states. An opacity controller may receive requests from the device for a requested opacity, in response to sensor and/or logical inputs, and/or to match a selected presentation type. The opacity controller may adjust the opacity of at least one region of the opacity layer to the requested opacity, and a visual presenter may present the visual output of the device with the opacity layer.

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