Container closure with overlying needle penetrable and thermally resealable portion and underlying portion compatible with fat containing liquid product, and related method
    241.
    发明授权
    Container closure with overlying needle penetrable and thermally resealable portion and underlying portion compatible with fat containing liquid product, and related method 有权
    容器封闭,覆盖针穿透和热再密封部分以及与包含液体产品的脂肪相容的底层部分及相关方法

    公开(公告)号:US07954521B2

    公开(公告)日:2011-06-07

    申请号:US11339966

    申请日:2006-01-25

    Abstract: A container and method are provided for storing fat containing liquid products. The container includes a body defining a storage chamber for receiving the product, and a container closure. A first material portion forms at least most of the surface area overlying the storage chamber that can contact any product therein. Neither the body nor the first material portion leach more than a predetermined amount of leachables into the product or undesirably alter a taste profile thereof. A needle penetrable and thermally resealable second material portion either (i) overlies the first material portion and cannot contact any product within the storage chamber, or (ii) forms a substantially lesser surface area overlying the storage chamber that can contact any product therein in comparison to the first material portion. A sealing portion is engageable with the body to form a substantially dry hermetic seal between the container closure and body.

    Abstract translation: 提供容器和方法来储存含有液体产品的脂肪。 容器包括限定用于接收产品的储存室的主体和容器封闭件。 第一材料部分形成至少大部分覆盖储存室的表面区域,该表面区域可接触其中的任何产品。 身体和第一材料部分都不会将超过预定量的可浸出物浸入产品中或者不期望地改变其味道特征。 针可穿透和可热再密封的第二材料部分(i)覆盖在第一材料部分上并且不能接触储存室内的任何产品,或(ii)形成覆盖存储室的基本上较小的表面区域,其可以与其中的任何产品接触 到第一材料部分。 密封部分可与主体接合以在容器封闭件和主体之间形成基本上干燥的气密密封。

    Container Closure with Overlying Needle Penetrable and Resealable Portion and Underlying Portion Compatible with Fat Containing Liquid Product, and Related Method
    243.
    发明申请
    Container Closure with Overlying Needle Penetrable and Resealable Portion and Underlying Portion Compatible with Fat Containing Liquid Product, and Related Method 有权
    集装箱封闭与上覆针可穿透和可重复密封的部分和相关部分兼容含有液体产品的脂肪及相关方法

    公开(公告)号:US20110052768A1

    公开(公告)日:2011-03-03

    申请号:US12894224

    申请日:2010-09-30

    Abstract: A container and method are provided for storing fat containing liquid products. The container includes a body defining a storage chamber for receiving the product, and a container closure. A first material portion forms at least most of the surface area overlying the storage chamber that can contact any product therein. Neither the body nor the first material portion leach more than a predetermined amount of leachables into the product or undesirably alter a taste profile thereof. A needle penetrable and thermally resealable second material portion either (i) overlies the first material portion and cannot contact any product within the storage chamber, or (ii) forms a substantially lesser surface area overlying the storage chamber that can contact any product therein in comparison to the first material portion. A sealing portion is engageable with the body to form a substantially dry hermetic seal between the container closure and body.

    Abstract translation: 提供容器和方法来储存含有液体产品的脂肪。 容器包括限定用于接收产品的储存室的主体和容器封闭件。 第一材料部分形成至少大部分覆盖储存室的表面区域,该表面区域可接触其中的任何产品。 身体和第一材料部分都不会将超过预定量的可浸出物浸入产品中或者不期望地改变其味道特征。 针可穿透和可热再密封的第二材料部分(i)覆盖在第一材料部分上并且不能接触储存室内的任何产品,或(ii)形成覆盖存储室的基本上较小的表面区域,其可以与其中的任何产品接触 到第一材料部分。 密封部分可与主体接合以在容器封闭件和主体之间形成基本上干燥的气密密封。

    ONE-WAY VALVE AND APPARATUS AND METHOD OF USING THE VALVE
    244.
    发明申请
    ONE-WAY VALVE AND APPARATUS AND METHOD OF USING THE VALVE 有权
    单向阀和装置以及使用阀的方法

    公开(公告)号:US20110024463A1

    公开(公告)日:2011-02-03

    申请号:US12901422

    申请日:2010-10-08

    Abstract: A flexible pouch and valve assembly is provided for aseptically storing a substance, dispensing multiple portions of the stored substance therefrom, and maintaining substance remaining in the pouch in an aseptic condition sealed with respect to ambient atmosphere. The flexible pouch and valve assembly are receivable within a relatively rigid housing, and are adapted to cooperate with a pump for pumping discrete portions of substance from the pouch and through the one-way valve to dispense the substance therefrom. The assembly comprises a flexible pouch defining therein a variable-volume storage chamber sealed with respect to the ambient atmosphere for aseptically storing therein multiple portions of the substance. A one-way valve of the assembly includes a valve body defining an axially-extending valve seat and at least one flow aperture extending through the valve body and/or the valve seat.

    Abstract translation: 提供了一种柔性袋和阀组件,用于无菌存储物质,从其中分配多部分储存物质,并将残留在袋中的物质保持在相对于环境大气密封的无菌状态。 柔性袋和阀组件可接收在相对刚性的壳体内,并且适于与泵协作,用于泵送物质的离散部分并且通过单向阀从其分配物质。 组件包括柔性袋,其中限定有相对于环境大气密封的可变容积存储室,用于将物质的多个部分无菌存储。 组件的单向阀包括限定轴向延伸的阀座的阀体和延伸穿过阀体和/或阀座的至少一个流动孔。

    Resealable Containers and Methods of Making, Filling and Resealing Same
    246.
    发明申请
    Resealable Containers and Methods of Making, Filling and Resealing Same 审中-公开
    可密封的容器和制造,填充和再密封的方法相同

    公开(公告)号:US20100236659A1

    公开(公告)日:2010-09-23

    申请号:US12789565

    申请日:2010-05-28

    Abstract: Disclosed is a uniquely configured medicament vial assembly which includes a storage vial, a stopper member and a securing ring. The vial assembly is configured to improve healthcare worker safety by providing a shielded gripping location to aid in the reduction of accidental needle sticks. The storage vial has a body portion which defines an interior chamber for storing a predetermined medicament and a neck portion through which medicament is received into and withdrawn from the interior chamber. The stopper member is inserted into the mouth of the vial and establishes a first seal. The securing ring is engaged with the mouth of the vial and adapted and configured for retaining the stopper member within the vial mouth and effectuating a second seal. The securing ring is formed from a thermoplastic and/or elastic material. Preferably, the securing ring is formed by molding the thermoplastic and/or elastic material over a portion of the storage vial and stopper member when engaged within the vial mouth.

    Abstract translation: 公开了一种独特构造的药物小瓶组件,其包括存储小瓶,止动构件和固定环。 小瓶组件被配置成通过提供屏蔽夹持位置来帮助减少意外的针棒来改善医护人员的安全性。 存储小瓶具有主体部分,其限定用于存储预定药物的内部腔室和颈部部分,药物通过所述颈部部分容纳到内部腔室中并从内部腔室中排出。 止动件插入小瓶的口中并建立第一密封。 固定环与小瓶的口接合并适于和构造成将止动件保持在小瓶口内并实现第二密封。 固定环由热塑性和/或弹性材料形成。 优选地,固定环通过在接合在小瓶口中时将热塑性和/或弹性材料模制在存储小瓶和止动构件的一部分上而形成。

    LYOPHILIZATION METHOD AND DEVICE
    248.
    发明申请
    LYOPHILIZATION METHOD AND DEVICE 有权
    LYOPHILIZATION方法和设备

    公开(公告)号:US20100154245A1

    公开(公告)日:2010-06-24

    申请号:US12534730

    申请日:2009-08-03

    Applicant: Daniel Py

    Inventor: Daniel Py

    Abstract: A lyophilization device configured for use in a lyophilization process has a body defining a chamber for receiving a liquid to be lyophilized, and a stopper creating a liquid-tight seal between the chamber and ambient atmosphere to form a sealed, empty sterile chamber. The stopper is adapted so that the chamber may be sterile filled with the substance through the stopper. A fluid passageway is formed through the stopper, through which the chamber is evacuated. The substance is lyophilized, the fluid passageway is closed, and the lyophilized substance is hermetically sealed within the chamber.

    Abstract translation: 构造成用于冻干过程的冻干装置具有限定用于接收要冷冻干燥的液体的室的主体和在室与环境大气之间形成液密密封的塞子,以形成密封的空的无菌室。 塞子适于使得腔室可以通过止动器无菌地填充物质。 通过塞子形成流体通道,通过该塞子抽空腔室。 物质被冻干,流体通道关闭,冻干物质密封在腔室内。

    Sealed containers and methods of making and filling same
    249.
    发明授权
    Sealed containers and methods of making and filling same 有权
    密封容器及其制造和填充方法

    公开(公告)号:US07726352B2

    公开(公告)日:2010-06-01

    申请号:US11515162

    申请日:2006-09-01

    Abstract: Disclosed is a uniquely configured medicament vial assembly which includes a storage vial, a stopper member and a securing ring. The vial assembly is configured to improve healthcare worker safety by providing a shielded gripping location to aid in the reduction of accidental needle sticks. The storage vial has a body portion which defines an interior chamber for storing a predetermined medicament and a neck portion through which medicament is received into and withdrawn from the interior chamber. The stopper member is inserted into the mouth of the vial and establishes a first seal. The securing ring is engaged with the mouth of the vial and adapted and configured for retaining the stopper member within the vial mouth and effectuating a second seal. The securing ring is formed from a thermoplastic and/or elastic material. Preferably, the securing ring is formed by molding the thermoplastic and/or elastic material over a portion of the storage vial and stopper member when engaged within the vial mouth.

    Abstract translation: 公开了一种独特构造的药物小瓶组件,其包括存储小瓶,止动构件和固定环。 小瓶组件被配置成通过提供屏蔽夹持位置来帮助减少意外的针棒来改善医护人员的安全性。 存储小瓶具有主体部分,其限定用于存储预定药物的内部腔室和颈部部分,药物通过所述颈部部分容纳到内部腔室中并从内部腔室中排出。 止动件插入小瓶的口中并建立第一密封。 固定环与小瓶的口接合并适于和构造成将止动件保持在小瓶口内并实现第二密封。 固定环由热塑性和/或弹性材料形成。 优选地,固定环通过在接合在小瓶口中时将热塑性和/或弹性材料模制在存储小瓶和止动构件的一部分上而形成。

    Delivery device and method of delivery
    250.
    发明授权
    Delivery device and method of delivery 失效
    送货装置和送货方式

    公开(公告)号:US07678089B2

    公开(公告)日:2010-03-16

    申请号:US10990164

    申请日:2004-11-15

    Abstract: An ophthalmic delivery device includes a body defining a fluid reservoir and a pump in fluid communication with the reservoir. The delivery device also includes a nozzle that includes a dosage chamber for holding a dosage of fluid, a valve seat, and a valve cover. The valve cover extends about the valve seat and forms an interface therebetween and the valve seat includes an outlet aperture. The interface is in fluid communication with the outlet aperture and the dosage chamber, and at least part of the valve cover is movable between (i) a closed position with the valve cover engaging the valve seat to close the interface and form a fluid-tight seal therebetween, and (ii) an open position with at least part of the valve cover spaced away from the valve seat in response to fluid flowing through the outlet aperture at a pressure greater than a valve opening pressure to allow the passage of pressurized fluid therebetween. The valve seat and the valve cover are dimensioned to dispense the dosage of fluid through the interface at a velocity of equal to or less than 6 meters per second.

    Abstract translation: 眼科输送装置包括限定流体储存器的主体和与储存器流体连通的泵。 输送装置还包括喷嘴,该喷嘴包括用于保持一定量的流体的剂量室,阀座和阀盖。 阀盖围绕阀座延伸并且在它们之间形成界面,并且阀座包括出口孔。 所述界面与所述出口孔和所述剂量室流体连通,并且所述阀盖的至少一部分可在(i)与所述阀盖接合所述阀座的关闭位置之间移动以关闭所述界面并形成流体密封 密封在其间,和(ii)打开位置,其中阀盖的至少一部分响应于流体以大于阀打开压力的压力流过出口孔而与阀座间隔开,以允许加压流体在其间通过 。 阀座和阀盖的尺寸设计为以等于或小于6米/秒的速度通过界面分配流体的剂量。

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