Abstract:
An impact absorbing footwear device employs opposed planar sole portions engaged by a selective resistance coupling that biases the opposed planar sole portions in a non-linear manner in response to forces exerted by the wearer against the sole portion in frictional contact with a floor surface. The planar sole portions are disposed in a footwear appliance that takes the form of an athletic shoe sole. The selective resistance coupling includes a plurality of resilient deformation members that engage the planar sole portions in an opposed circumferentially aligned manner, selectively deform in response to pressure exerted by the wearer for preventing ACL and other impact related injuries, and recover to an undeformed rest position without breakaway to allow the wearer uninterrupted usage while dampening forces that surpass an injury threshold from the resilient deformation that allows the planar sole portions to temporarily misalign.
Abstract:
Methods and systems for clean-up of hazardous spills are provided. In some aspects, there is provided a system for burning an water-oil emulsion that includes an enclosure configured to hold a water-oil emulsion; one or more conductive rods disposed throughout the enclosure, each rod of the one or more roads having a heater portion to be submerged in the water-oil emulsion and a collector portion to project above the water-oil emulsion, wherein the collector portion is longer than the heater portion; and a delivery system for supplying an water-oil emulsion to the enclosure, the delivery system is configured to maintain a constant level of the water-oil emulsion in the enclosure as the water-oil emulsion is burned. The enclosure may further include one or more adjustable air inlets.
Abstract:
Antimicrobial agents, compositions that include the agent(s) and use(s) thereof are provided. Also disclosed are screening assays for identifying antimicrobial agents.
Abstract:
A modular engineered tissue construct includes a plurality of fused self-assembled, scaffold-free, high-density cell aggregates. At least one cell aggregate includes a plurality of cells and a plurality of biocompatible and biodegradable nanoparticles and/or microparticles that are incorporated within the cell aggregates. The nanoparticles and/or microparticles acting as a bulking agent within the cell aggregate to increase the cell aggregate size and/or thickness and improve the mechanical properties of the cell aggregate as well as to deliver bioactive agents.
Abstract:
Compositions that include fibrin microthreads are provided. The compositions can include one or more therapeutic agents including cytokines and interleukins, extracellular matrix proteins and/or biologically active fragments thereof (e.g., RGD-containing peptides), hormones, vitamins, nucleic acids, chemotherapeutics, antibiotics, and cells. Also provided are methods of making compositions that include fibrin microthreads. Also provided are methods for using the compositions to repair or ameliorate damaged or defective organs or tissues.
Abstract:
Antimicrobial agents, compositions that include the agent(s) and use(s) thereof are provided. Also disclosed are screening assays for identifying antimicrobial agents.
Abstract:
An apparatus comprising a crank-slider linkage and a rocker link. The crank-slider linkage has a crank coupled to the slider by a jointed connecting rod. The jointed connecting rod has a first link and a second link. The first link is coupled to the second link by a first revolute joint. The first link is coupled to the crank and has a longitudinal axis. The rocker link has a rocker end and a ground end. The rocker end is coupled to the jointed connecting rod. The ground end is coupled to ground by a second revolute joint. The rocker link and the second link are disposed on a common side of the longitudinal axis.
Abstract:
Compositions that include fibrin microthreads are provided. The compositions can include one or more therapeutic agents including cytokines and interleukins, extracellular matrix proteins and/or biologically active fragments thereof (e.g., RGD-containing peptides), hormones, vitamins, nucleic acids, chemotherapeutics, antibiotics, and cells. Also provided are methods of making compositions that include fibrin microthreads. Also provided are methods for using the compositions to repair or ameliorate damaged or defective organs or tissues.
Abstract:
A digital instructional environment leverages an infrared eye-tracker to monitor a learner's reading and viewing of text and simulations for subject matter. The system detects out-of-order reading/viewing patterns that could lead to poor comprehension. The digital learning environment communicates with other tutorial components including simulation environments, pedagogical agents and may respond in real-time to such patterns with messages that guide learners (knowledge acquirers) to return to effective reading/viewing patterns so as to promote effective construction of mental model(s) developed during knowledge acquisition/learning.
Abstract:
Drying a planar substrate such as paper sheet goods for packing materials includes layering a phase change material (PCM) on a substrate, in which the substrate has a moisture content and adapted for moisture removal to form a planar medium. A drying process disposes the substrate adjacent to a plurality of rollers and heat the layered substrate to a predetermined temperature based on a specific heat of the PCM. The rollers advance the layered substrate in series through pocket ventilation regions between the heat transfer elements, such that the pocket ventilation regions permit drying of the substrate enhanced by the specific heat of the temperature sensitive material. Upon drying, the layered substrate forms the planar medium suitable for use as a packing medium or other suitable application. The pocket ventilation regions are based on the PCM to facilitate drying and eradication of moisture from the paper planar substrate.