公开(公告)号：US6090048A

公开(公告)日：2000-07-18

申请号：US29813

申请日：1998-03-10

申请人： Thomas Hertz ,  Sven Jonsson ,  Jan Sternby

发明人： Thomas Hertz ,  Sven Jonsson ,  Jan Sternby

IPC分类号： A61B5/00 ,  A61B5/0215 ,  A61M1/14 ,  A61M1/16 ,  A61M1/34 ,  A61M1/36 ,  A61M5/168 ,  A61B5/02 ,  A61M1/00 ,  A61M37/00

CPC分类号： A61M5/16859 ,  A61M1/3656 ,  A61M1/16 ,  A61M1/34 ,  A61M1/3639 ,  A61M2205/13

摘要： Methods for detecting the condition of a catheter providing access to a patient's blood vessel are disclosed in which the blood is supplied to an extracorporeal blood flow circuit. The method includes generating a pressure wave on one side of one of the access points for supplying blood to the extracorporeal blood flow circuit or returning the blood to the patient, then sensing the pressure wave on the other side of the access points. Apparatus for detecting the condition of the catheter are also provided.

摘要翻译： PCT No.PCT / SE96 / 01127 Sec。 371日期1998年3月10日 102（e）1998年3月10日PCT PCT 1996年9月11日PCT公布。 公开号WO97 / 10013 PCT 1997年3月20日公开了用于检测提供对患者血管通路的导管状态的方法，其中将血液供应到体外血流回路。 该方法包括在一个接入点的一侧上产生压力波，用于向体外血流回路供血或将血液返回给患者，然后检测接入点另一侧的压力波。 还提供了用于检测导管状况的装置。

公开(公告)号：US6039720A

公开(公告)日：2000-03-21

申请号：US011412

申请日：1998-02-06

申请人： Anders Wieslander

发明人： Anders Wieslander

IPC分类号： A61J1/05 ,  A61J1/00 ,  A61J1/10 ,  A61J1/20 ,  A61M1/28 ,  A61B19/00

CPC分类号： A61J1/2093 ,  A61J1/10 ,  A61J1/2027 ,  A61M1/287

摘要： A container for a sterile medical solution comprises an upper surface, a lower surface, and a rigid top border having a central portion and peripheral portions. At least one separation line joints the upper and lower surfaces of the container to form first and second compartments. The top border of the container includes lines of weakness in the central portion thereof to form a hinged connection between the peripheral portions of the top border so that solutions in the first and second compartments are more quickly mixed when openable connectors between the compartments are broken.

摘要翻译： PCT No.PCT / SE96 / 00984 Sec。 371日期1998年2月6日 102（e）日期1998年2月6日PCT提交1996年8月2日PCT公布。 公开号WO97 / 05851 日期1997年2月20日用于无菌医用溶液的容器包括上表面，下表面和具有中心部分和周边部分的刚性顶部边界。 至少一个分离线接合容器的上表面和下表面以形成第一和第二隔室。 容器的顶部边界在其中心部分包​​括弱线，以在顶部边界的周边部分之间形成铰链连接，使得在隔室之间的可打开连接器断开时，第一和第二隔室中的溶液更快速地混合。

公开(公告)号：USD412578S

公开(公告)日：1999-08-03

申请号：US79687

申请日：1997-11-21

申请人： H.ang.kan Andersson ,  Mats Nilsson

设计人： H.ang.kan Andersson ,  Mats Nilsson

公开(公告)号：US5861555A

公开(公告)日：1999-01-19

申请号：US964732

申请日：1997-11-05

申请人： Sture Hobro ,  Erik Linderup ,  Leif Mattisson

发明人： Sture Hobro ,  Erik Linderup ,  Leif Mattisson

IPC分类号： A61M1/14 ,  A61M1/16 ,  G01F25/00 ,  G01F1/68

CPC分类号： A61M1/16 ,  A61M1/1647 ,  A61M1/1662 ,  A61M1/1664 ,  A61M1/1692

摘要： Methods for measuring the flow differential through a dialysis machine are disclosed in which the dialysis machine includes a heat exchanger having a primary side and a secondary side for exchanging heat therebetween. The method includes measuring the temperature differences across the primary and secondary sides of the heat exchanger and calculating the flow differential based upon these measured temperature differences. Apparatus for measuring such a flow differential is also disclosed, as are methods for calibrating that apparatus.

摘要翻译： 公开了通过透析机测量流量差的方法，其中透析机包括具有初级侧和次级侧之间用于在其间进行热交换的热交换器。 该方法包括测量热交换器的一次侧和二次侧的温差，并基于这些测量的温度差来计算流量差。 还公开了用于测量这种流量差的装置，校准该装置的方法也是如此。

公开(公告)号：US5792367A

公开(公告)日：1998-08-11

申请号：US693263

申请日：1996-08-16

申请人： Leif Mattisson ,  Gunilla Wejfeldt

发明人： Leif Mattisson ,  Gunilla Wejfeldt

IPC分类号： G01F1/00 ,  A61M1/14 ,  A61M1/16 ,  B01D61/32 ,  G01F1/36 ,  G01F25/00 ,  G05D7/06 ,  B01D61/30 ,  B01D65/10

CPC分类号： G05D7/0682 ,  A61M1/16 ,  A61M1/1647 ,  G01F1/363 ,  G01F25/003 ,  Y10S210/929

摘要： Apparatus for monitoring flow of a dialysis fluid through a dialyzer is disclosed including a computer for calculating the flow rate of the dialysis fluid into and out of the dialyzer based on the formula P-P.sub.O =k*Q.sup.n in which P is the pressure in the dialysis fluid between a throttle and a pump either upstream or downstream of the dialyzer, P.sub.O is the pressure in the dialysis fluid on the opposite side of the throttles from the pump, k is a characteristic coefficient for the throttle, Q is the flow of the dialysis fluid through the throttle, and N is a characteristic exponent for the throttle, and the apparatus includes microprocessor for calculating the values of k and P.sub.O prior to use and for calculating the value of P.sub.O during use of the dialyzer. Methods for carrying out such monitoring are also disclosed.

摘要翻译： PCT No.PCT / SE95 / 00166 Sec。 371日期：1996年8月16日 102（e）日期1996年8月16日PCT提交1995年2月17日PCT公布。 第WO95 / 22743号公报 日期1995年8月24日公开了一种通过透析器监测透析液流量的装置，其包括计算机，用于根据公式P-PO = k * Qn计算透析液进出透析器的流量，其中P 是在透析器上游或下游的节流阀和泵之间的透析液中的压力，PO是来自泵的节流阀相对侧的透析液体中的压力，k是节流阀的特征系数，Q 是通过节气门的透析流体的流动，N是节气门的特征指数，并且该装置包括用于在使用之前计算k和PO的值的微处理器，以及在使用透析器期间计算PO的值。 还公开了进行这种监视的方法。

公开(公告)号：US5788846A

公开(公告)日：1998-08-04

申请号：US593536

申请日：1996-01-29

申请人： Jan Sternby

发明人： Jan Sternby

IPC分类号： A61M1/14 ,  A61M1/16 ,  B01D61/32 ,  B01D61/34

CPC分类号： A61M1/16 ,  A61M1/1609 ,  A61M1/1619 ,  A61M2202/0421 ,  A61M2202/0498 ,  Y10S210/929

摘要： Methods for measuring the effect of dialysis treatments are disclosed in which a fraction of the used dialysis fluid is extracted downstream of the dialyzer for analysis of at least one substance such as urea, and in which the fraction of dialysis fluid is extracted through a branch conduit containing a pump. In accordance with this method, the total amount of used dialysis fluid is measured and the concentration of that substance in the extracted fraction is measured, and the total amount of that substance removed from the patient can then be calculated from these values. This invention is preferably intended for use in connection with hemodialysis, hemofiltration and hemodiafiltration.

摘要翻译： 公开了用于测量透析治疗效果的方法，其中使用的透析液的一部分在透析器的下游被提取用于分析至少一种物质如尿素，并且其中通过分支导管提取透析液的部分 包含一个泵。 根据该方法，测定所使用的透析液的总量，并测定萃取部分中该物质的浓度，然后根据这些值计算从患者中除去的物质的总量。 本发明优选旨在用于血液透析，血液滤过和血液透析滤过。

公开(公告)号：USD395082S

公开(公告)日：1998-06-09

申请号：US044863

申请日：1995-10-02

申请人： Raymond Edgson ,  Bo Olde ,  Lars-Fride Olsson

设计人： Raymond Edgson ,  Bo Olde ,  Lars-Fride Olsson

公开(公告)号：US5344231A

公开(公告)日：1994-09-06

申请号：US003844

申请日：1993-01-11

申请人： Lennart Jonsson ,  Stefan Knutsson

发明人： Lennart Jonsson ,  Stefan Knutsson

IPC分类号： A61J3/00 ,  A61M1/14 ,  A61M1/16 ,  B01F1/00 ,  B01F3/12 ,  B01F5/10 ,  B01F15/04

CPC分类号： B01F5/106 ,  A61M1/1656 ,  A61M1/1666 ,  B01F1/0038 ,  B01F15/00227 ,  B01F15/0408 ,  B01F3/1271 ,  B01F5/102 ,  B01F2001/0061 ,  B01F2003/125

摘要： Apparatus for the preparation of fluids intended for medical use is disclosed, including a source of pure water and at least one cartridge or other vessel containing a powder which is to be dissolved in the water for preparation of the desired fluid. The apparatus includes a container such that the water and a powder or powder concentrate can be mixed and a concentrate provided in the container, and a recirculation circuit for recirculation of the water or concentrate solution into the container for further mixing of the water and powder or powder concentrate to prepare a concentrate having a predetermined concentration.

公开(公告)号：US4762618A

公开(公告)日：1988-08-09

申请号：US868803

申请日：1986-05-29

申请人： Bengt-Ake G. Gummesson ,  Preben A. Petersen ,  Jan P. Sternby

发明人： Bengt-Ake G. Gummesson ,  Preben A. Petersen ,  Jan P. Sternby

IPC分类号： A61M1/14 ,  A61M1/16 ,  B01D61/22 ,  B01D61/32 ,  B01D13/00

CPC分类号： A61M1/16 ,  B01D61/22

摘要： Apparatus and methods are disclosed for controlling the flow of a fluid past a membrane in a dialyzer. The apparatus disclosed includes a fluid conduit for conducting the fluid both towards and away from the dialyzer, a flow constrictor for creating a pressure drop in the fluid conduit either upstream or downstream of the dialyzer, a pump for pumping the fluid through that conduit, and a pressure detector for measuring a pressure corresponding to that pressure drop so as to control the flow therein. The method disclosed includes flowing the fluid through an upstream fluid conduit to the dialyzer and through a downstream fluid conduit away from the dialyzer, producing a relatively constant flow in both the upstream and downstream fluid conduits, creating a pressure drop in one of the fluid conduits, pumping the fluid through that conduit, and measuring the pressure corresponding to that pressure drop so that the flow of the fluid in that conduit can be controlled thereby.

摘要翻译： 公开了用于控制流体经过透析器中的膜的流动的装置和方法。 所公开的装置包括用于将流体导向和远离透析器的流体导管，用于在透析器的上游或下游在流体导管中产生压降的流动压缩机，用于通过该导管泵送流体的泵，以及 用于测量与该压降相对应的压力以便控制其中的流量的压力检测器。 所公开的方法包括将流体通过上游流体导管流到透析器并且通过远离透析器的下游流体导管流动，在上游和下游流体导管中产生相对恒定的流量，在流体导管之一中产生压力降 ，通过该导管泵送流体，并测量与该压降相对应的压力，从而可以控制该管道中的流体流动。

公开(公告)号：US4313831A

公开(公告)日：1982-02-02

申请号：US104446

申请日：1979-12-17

申请人： Hans-Dieter Lehmann ,  Lars-Ake Larsson

发明人： Hans-Dieter Lehmann ,  Lars-Ake Larsson

IPC分类号： A61M1/36 ,  A61M1/16 ,  B01D15/00 ,  B01D13/00

CPC分类号： A61M1/1696 ,  B01D15/00

摘要： Processes and apparatus for the removal of waste metabolites from metabolite-containing solutions are disclosed. The disclosed processes include alternatively adsorbing and desorbing the metabolites on a pair of adsorbent-containing columns, each column being maintained at a reduced temperature during adsorption and at an elevated temperature during desorption, with the columns being flushed subsequent to desorption and prior to their re-use for adsorption thereon. The disclosed apparatus includes a pair of adsorbent-containing columns, means for alternatively delivering the metabolite containing solution to each of the columns for alternate adsorption and desorption thereon, means for withdrawing the metabolite containing solution from each of the columns, means for alternately flushing the columns subsequent to desorption and prior to adsorption thereon, and means for alternately maintaining the columns at reduced temperatures during adsorption and at elevated temperatures during desorption so that the effectiveness of the adsorbent for adsorption is increased during adsorption at the reduced temperatures.A disposable tube set for use in connection with such a pair of adsorbent containing columns is also disclosed, including a flexible inlet tube including a pair of inlet branches for delivery of the metabolite containing solution to each of the columns, and a flexible outlet tube including a pair of outlet tube branches for connection with the outlet end of each of the columns.

摘要翻译： 公开了从含代谢物的溶液中除去废代谢物的方法和设备。 所公开的方法包括替代地将代谢物吸附和解吸附在一对含吸附剂的柱上，每个塔在吸附过程中保持在降低的温度，并且在解吸期间在升高的温度下保持在降低的温度，同时在解吸附之后并在其再次 - 用于吸附。 所公开的装置包括一对含吸附剂的柱，用于将含有代谢物的溶液交替地输送到每个柱以用于在其上进行交替吸附和解吸的装置，用于从每个柱抽出含代谢物的溶液的装置，用于交替地将 在脱附之后和吸附之前的塔，以及用于在解吸期间在吸附期间和升高的温度下交替地将塔保持在降低的温度的装置，使得在降低的温度下吸附期间吸附剂的吸附效果增加。 还公开了一种用于与这种一对含吸附剂的柱结合使用的一次性管组，其包括柔性入口管，其包括用于将含代谢物溶液递送到每个柱的一对入口支管，以及柔性出口管，其包括 一对出口管分支，用于与每个柱的出口端连接。