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公开(公告)号:US20210198302A1
公开(公告)日:2021-07-01
申请号:US17269721
申请日:2019-08-21
Applicant: Kaleido Biosciences, Inc.
Inventor: Christopher Matthew Liu , John M. Geremia , Anastasia Lioubomirov , Max Hecht
Abstract: Aspects of the disclosure relate to oligosaccharide compositions and methods of making the same. Also provided are methods of using oligosaccharide compositions as microbiome metabolic therapies for reducing ammonia levels and for the treatment of hyperammonemia-related diseases (e.g., urea cycle disorders and hepatic encephalopathy).
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公开(公告)号:US20210164926A1
公开(公告)日:2021-06-03
申请号:US17157292
申请日:2021-01-25
Applicant: Kaleido Biosciences, Inc.
Inventor: Christopher Matthew Liu , Anastasia Lioubomirov , John M. Geremia , Mitchell Antalek , Jonathan Lawrence , Tatyana Yatsunenko , Brian Meehan
Abstract: Aspects of the disclosure relate to oligosaccharide compositions and methods of making the same. Also provided are methods of using oligosaccharide compositions as microbiome metabolic therapies for reducing ammonia levels and for the treatment of related diseases.
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公开(公告)号:US20200093851A1
公开(公告)日:2020-03-26
申请号:US16395929
申请日:2019-04-26
Applicant: KALEIDO BIOSCIENCES, INC.
Inventor: Geoffrey A. von Maltzahn , Jared Silverman , Yvonne J. Yamanaka , John Miles Milwid , John M. Geremia
IPC: A61K31/716 , A61K31/165 , A61K31/706 , A61K31/366 , A61K31/11 , A61K31/365 , A61K31/34 , A61K31/09 , A61K31/353 , A61K31/7034 , A61K31/12 , A61K31/7048 , A61K31/715
Abstract: Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said glycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.
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公开(公告)号:US09901595B2
公开(公告)日:2018-02-27
申请号:US15286382
申请日:2016-10-05
Applicant: KALEIDO BIOSCIENCES, INC.
Inventor: Geoffrey A. von Maltzahn , Jared Silverman , Yvonne J. Yamanaka , John Miles Milwid , John M. Geremia
IPC: A61K31/716
CPC classification number: A61K31/716 , A61K31/09 , A61K31/11 , A61K31/12 , A61K31/165 , A61K31/34 , A61K31/353 , A61K31/365 , A61K31/366 , A61K31/7034 , A61K31/7048 , A61K31/706 , A61K31/715 , A61K2035/115
Abstract: Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said glycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.
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公开(公告)号:US20170151269A1
公开(公告)日:2017-06-01
申请号:US15385331
申请日:2016-12-20
Applicant: KALEIDO BIOSCIENCES, INC.
Inventor: Geoffrey A. von Maltzahn , Jared Silverman , Yvonne J. Yamanaka , John Miles Milwid , John M. Geremia
IPC: A61K31/702 , A61K35/741 , A61K45/06 , A61K31/7004 , A61K31/7016
CPC classification number: A61K31/702 , A23L33/10 , A23P10/00 , A23V2002/00 , A61K31/7004 , A61K31/7016 , A61K31/716 , A61K31/733 , A61K35/741 , A61K45/06 , A61K2035/115 , A61P1/00 , Y02A50/475 , Y02A50/481
Abstract: Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said glycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.
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公开(公告)号:US20160213702A1
公开(公告)日:2016-07-28
申请号:US15017396
申请日:2016-02-05
Applicant: KALEIDO BIOSCIENCES, INC.
Inventor: Geoffrey A. von Maltzahn , Jared Silverman , Yvonne J. Yamanaka , John Miles Milwid , John M. Geremia
IPC: A61K31/715 , A61K31/12 , A61K31/7034 , A61K31/353 , A61K31/165 , A61K31/34 , A61K31/365 , A61K31/11 , A61K31/366 , A61K31/706 , A61K31/7048 , A61K31/09
CPC classification number: A61K31/716 , A61K31/09 , A61K31/11 , A61K31/12 , A61K31/165 , A61K31/34 , A61K31/353 , A61K31/365 , A61K31/366 , A61K31/7034 , A61K31/7048 , A61K31/706 , A61K31/715 , A61K2035/115
Abstract: Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said glycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.
Abstract translation: 提供了聚糖治疗剂,其药物组合物和医药食品,任选地包含微量营养素,多酚,益生元,益生菌或其它药剂的制备方法及其制备方法。 还提供了使用所述聚糖治疗剂的方法,例如, 用于调节人类胃肠道微生物群并治疗生殖器发育不良。
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27.
公开(公告)号:US20230165881A1
公开(公告)日:2023-06-01
申请号:US17920720
申请日:2021-04-29
Applicant: Kaleido Biosciences, Inc.
Inventor: Jonathan Lawrence , Jeffrey Meisner , Christopher Matthew Liu , Madeline Rosini , Max Hecht , Mark Wingertzahn , Geoffrey A. von Maltzahn
IPC: A61K31/702 , A61P31/16 , A61P31/14
CPC classification number: A61K31/702 , A61P31/16 , A61P31/14
Abstract: Aspects of the disclosure relate to oligosaccharide compositions and methods of making the same. Also provided are methods of using oligosaccharide compositions as microbiome metabolic therapies for treating respiratory viral illnesses, such as COVID-19.
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公开(公告)号:US20220233560A1
公开(公告)日:2022-07-28
申请号:US17609234
申请日:2020-05-08
Applicant: Kaleido Biosciences, Inc.
Inventor: Tatyana Yatsunenko , Jonathan Lawrence , Madeline Rosini , Max Hecht , Christopher Matthew Liu
IPC: A61K31/702 , A61P1/00 , A61P31/04 , C07H3/06 , C07H1/00 , A61P31/10 , A61K35/741 , A61K45/06
Abstract: Aspects of the disclosure relate to oligosaccharide compositions and methods of making the same. Also provided are methods of using oligosaccharide compositions as microbiome metabolic therapies for reducing pathogen levels and/or abundance and for the treatment of related diseases.
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公开(公告)号:US20210395399A1
公开(公告)日:2021-12-23
申请号:US17292104
申请日:2019-11-08
Applicant: DSM IP Assets B.V. , Midori USA, Inc. , KALEIDO BIOSCIENCES, INC.
Inventor: Manuela BAUR , Estel CANET-MARTINEZ , John Michael GEREMIA , Ulrich HOELLER , Alexandra Anne Emmanuelle SCHATTNER , Guido WAHL
Abstract: The present disclosure relates to selective analytical methods for the detection and/or quantification of an oligosaccharide preparation in a nutritional composition such as an animal feed. Also disclosed are methods of manufacturing a nutritional composition comprising an oligosaccharide preparation, the presence or concentration of which can be selectively detected or determined.
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公开(公告)号:US11169101B2
公开(公告)日:2021-11-09
申请号:US17157292
申请日:2021-01-25
Applicant: Kaleido Biosciences, Inc.
Inventor: Christopher Matthew Liu , Anastasia Lioubomirov , John M. Geremia , Mitchell Antalek , Jonathan Lawrence , Tatyana Yatsunenko , Brian Meehan
Abstract: Aspects of the disclosure relate to oligosaccharide compositions and methods of making the same. Also provided are methods of using oligosaccharide compositions as microbiome metabolic therapies for reducing ammonia levels and for the treatment of related diseases.
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