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公开(公告)号:US20080266117A1
公开(公告)日:2008-10-30
申请号:US11742448
申请日:2007-04-30
申请人: Xuedong Song , James Matthew Takeuchi , Kaiyuan Yang , Shawn Jeffery Sullivan , Sridhar Ranganathan
发明人: Xuedong Song , James Matthew Takeuchi , Kaiyuan Yang , Shawn Jeffery Sullivan , Sridhar Ranganathan
CPC分类号: A61F13/42
摘要: Embodiments of the invention provide a sensor for detecting the presence of fluid in an absorbent article. The sensor may include a fluid activated battery. Fluid received in the absorbent article may connect electrodes of the fluid activated battery and cause a voltage to be generated between battery electrodes. The voltage generated between the electrodes may provide power to the sensor circuit. In one embodiment, the fluid activated battery may be configured to detect the presence of fluid in the absorbent article and the presence and/or amount of particular substances in the received fluid.
摘要翻译: 本发明的实施例提供一种用于检测吸收制品中流体存在的传感器。 传感器可以包括流体活化的电池。 容纳在吸收性物品中的流体可以连接流体活化电池的电极,并且在电池电极之间产生电压。 电极之间产生的电压可以为传感器电路提供电力。 在一个实施例中,流体活化电池可被配置为检测吸收制品中流体的存在以及接收流体中特定物质的存在和/或量。
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公开(公告)号:US20080145272A1
公开(公告)日:2008-06-19
申请号:US11640435
申请日:2006-12-15
申请人: Shawn R. Feaster , Kaiyuan Yang , Ning Wei , Chibueze O. Chidebelu-Eze , James M. Takeuchi , Rosann M. Kaylor , Enrico L. DiGiammarino , Jeffrey E. Fish
发明人: Shawn R. Feaster , Kaiyuan Yang , Ning Wei , Chibueze O. Chidebelu-Eze , James M. Takeuchi , Rosann M. Kaylor , Enrico L. DiGiammarino , Jeffrey E. Fish
CPC分类号: B01L3/5023 , A61B5/150022 , A61B5/150343 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150717 , A61B5/150824 , A61B5/15105 , A61B5/15113 , A61B5/15117 , A61B5/15186 , A61B5/1519 , A61B5/157 , B01L2200/0605 , B01L2200/16 , B01L2300/0672 , B01L2300/0867 , B01L2400/0683 , G01N33/491
摘要: A lateral flow assay device includes a housing, and a test strip disposed within the housing having a membrane with a detection region and a collection region. A sample meter includes a first end for absorption of a test sample, and a storage section that receives and stores at least a component of the test sample. An opening in the housing is sized for insertion of the sample meter into the housing such that the storage section of the sample meter is disposed adjacent the collection region of the membrane. The test sample component is transferable from the storagesection to the collection region for subsequent migration to the detection region. An activatable isolation mechanism is provided within the housing and is disposed so as to isolate portions of the sample meter storage section upon activation thereof such that a defined length of the storage section is presented to the collection region of the membrane.
摘要翻译: 侧流测定装置包括壳体和设置在壳体内的测试条,其具有带有检测区域和收集区域的膜。 样品计量器包括用于吸收测试样品的第一端和接收并存储至少测试样品的组分的存储部分。 壳体中的开口的尺寸用于将样品计量器插入到壳体中,使得样品计量器的存储部分邻近膜的收集区域设置。 测试样品组分可以从储存区转移到收集区域,以便随后迁移到检测区域。 在壳体内提供可激活的隔离机构,并且被设置成在启动时分离样品计量存储部分的部分,使得存储部分的限定长度被呈现给膜的收集区域。
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公开(公告)号:US07314763B2
公开(公告)日:2008-01-01
申请号:US10228838
申请日:2002-08-27
申请人: Xuedong Song , Rosann Kaylor , Shawn Feaster , Kaiyuan Yang
发明人: Xuedong Song , Rosann Kaylor , Shawn Feaster , Kaiyuan Yang
IPC分类号: G01N33/553 , G01N31/00 , G01N33/31 , G01N33/53
CPC分类号: G01N33/54366 , B01L3/502761 , B01L2200/0668 , B01L2300/0825 , B01L2400/0406 , B01L2400/043 , B01L2400/0677 , G01N33/54333 , Y10S435/969 , Y10S435/97 , Y10T436/10
摘要: A fluidics-based assay device for detecting the presence or quantity of an analyte residing in a test sample is provided. The device utilizes a self-calibrated magnetic binding assay format (e.g., sandwich, competitive, etc.) that includes detection probes capable of generating a detection signal (e.g., fluorescent non-magnetic particles) and calibration probes capable of generating a calibration signal (e.g., fluorescent magnetic particles). The amount of the analyte within the test sample is proportional (e.g., directly or inversely) to the intensity of the detection signal calibrated by the intensity of the calibration signal. It has been discovered that the fluidics-based device of the present invention provides an accurate, inexpensive, and readily controllable method of determining the presence of an analyte in a test sample.
摘要翻译: 提供了一种用于检测驻留在测试样品中的分析物的存在或数量的基于流体学的测定装置。 该装置使用包括能够产生检测信号的检测探针(例如,荧光非磁性颗粒)和能够产生校准信号的校准探针的自校准磁结合测定格式(例如,夹层,竞争性等) 例如荧光磁性颗粒)。 测试样品内的分析物的量与由校准信号的强度校准的检测信号的强度成正比(例如,直接或反向)。 已经发现,本发明的基于流体的装置提供了确定测试样品中分析物的存在的精确,便宜且易于控制的方法。
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公开(公告)号:US20070134811A1
公开(公告)日:2007-06-14
申请号:US11301631
申请日:2005-12-13
申请人: James Takeuchi , Xuedong Song , Kaiyuan Yang , Ning Wei , Shawn Feaster
发明人: James Takeuchi , Xuedong Song , Kaiyuan Yang , Ning Wei , Shawn Feaster
IPC分类号: G01N33/558
CPC分类号: G01N33/558 , Y10S436/825 , Y10T436/107497 , Y10T436/108331 , Y10T436/25375 , Y10T436/25625
摘要: A diagnostic method and associated test kit for detecting an analyte residing in a test sample is provided. A sample membrane is utilized having a collection region and a detection region, the collection region having a known saturation volume for the intended test sample. A barrier is defined between the collection region and the detection region. The collection region is saturated with the test sample having a volume of less than about 100 microliters so that a known volume of the test sample is contained in the collection region. The barrier is removed from between the collection region and detection region of the membrane and a diluent is supplied to the collection region of the membrane to facilitate flow of the test sample from the collection region to the detection region of the membrane.
摘要翻译: 提供了用于检测驻留在测试样品中的分析物的诊断方法和相关测试试剂盒。 使用具有收集区域和检测区域的样品膜,所述收集区域具有用于预期测试样品的已知饱和体积。 在收集区域和检测区域之间限定屏障。 收集区域用体积小于约100微升的测试样品饱和,使得已知体积的测试样品被包含在收集区域中。 从收集区域和膜的检测区域之间移除屏障,并且将稀释剂供应到膜的收集区域,以促进测试样品从收集区域流到膜的检测区域。
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公开(公告)号:US20070134810A1
公开(公告)日:2007-06-14
申请号:US11300650
申请日:2005-12-14
申请人: Kaiyuan Yang , Shawn Feaster , Ning Wei , Rosann Kaylor , Chibueze Chidebelu-Eze
发明人: Kaiyuan Yang , Shawn Feaster , Ning Wei , Rosann Kaylor , Chibueze Chidebelu-Eze
IPC分类号: G01N33/558
CPC分类号: G01N33/54366 , B01L3/5023 , B01L2200/027 , B01L2300/0681 , B01L2300/0825 , B01L2300/0867 , B01L2400/0406 , B01L2400/0683 , G01N33/558 , Y10S436/825 , Y10T436/107497 , Y10T436/108331
摘要: A diagnostic method and associated test kit for detecting an analyte residing in a test sample is provided. The kit includes a housing, and a membrane disposed within the housing having a detection region and a collection region. A blood sample meter is provided having a first end for absorption of a blood sample, a filtering section adjacent to the first end that filters red blood cell components from the blood sample, and a storage section adjacent to the filtering section that receives plasma or serum from the filtering section. An opening in the housing is sized for insertion of the sample meter into the housing such that the storage section of the sample meter is disposed in fluid communication with the collection region of the membrane. The plasma or serum is transferred from the storage section of the sample meter to the collection region of the membrane for subsequent migration to the detection region.
摘要翻译: 提供了用于检测驻留在测试样品中的分析物的诊断方法和相关测试试剂盒。 套件包括壳体和设置在壳体内的膜,其具有检测区域和收集区域。 提供血样计,其具有用于吸收血液样本的第一端,与第一端相邻的过滤部分,其从血液样品中过滤红细胞成分,以及与过滤部相邻的存储部,其接收血浆或血清 从过滤部分。 壳体中的开口的尺寸适于将样品计量器插入壳体中,使得样品计量器的存储部分设置成与膜的收集区域流体连通。 将血浆或血清从样品计量器的储存部分转移到膜的收集区域,以便随后迁移到检测区域。
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公开(公告)号:US20070134303A1
公开(公告)日:2007-06-14
申请号:US11302644
申请日:2005-12-14
申请人: Ali Yahiaoui , Kaiyuan Yang
发明人: Ali Yahiaoui , Kaiyuan Yang
CPC分类号: A61L15/46 , A41D31/30 , A61B42/00 , A61B46/40 , A61F13/104 , A61F2013/0031 , A61F2013/0091 , A61L2300/206 , A61L2300/404 , A61L2300/606 , Y10T442/2525
摘要: An antimicrobial protective article is described. The article has a first, outer surface that is coated at least partially with an antimicrobial agent containing polyhexamethylene biguanide (PHMB), and at least one or a combination of the following: chitosan, a chaotropic surfactant, polyols, copper oxide, and an organic acid, and a second, inner surface adapted to contact a wearer's skin that has a therapeutic agent. The present protective article can adapted for used in a variety of applications in the home or resort spas.
摘要翻译: 描述了一种抗微生物保护制品。 该制品具有至少部分地用含有聚六亚甲基双胍(PHMB)的抗微生物剂涂覆的第一外表面,以及以下的至少一种或组合:壳聚糖,离液状表面活性剂,多元醇,氧化铜和有机物 酸,以及适于接触具有治疗剂的穿着者皮肤的第二内表面。 本保护用品可适用于家庭或度假酒店水疗中的各种应用。
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公开(公告)号:US20070083980A1
公开(公告)日:2007-04-19
申请号:US11229021
申请日:2005-09-16
申请人: Kaiyuan Yang , Jeffrey Fish , Martin Shamis , Jason Baker , Oomman Thomas
发明人: Kaiyuan Yang , Jeffrey Fish , Martin Shamis , Jason Baker , Oomman Thomas
IPC分类号: A41D19/00
CPC分类号: A41D19/0006 , A41D19/0068 , A41D31/02
摘要: A polymer-coated protective garment is disclosed. The garment may be configured to fit around the arm, leg, foot or hand of a wearer. For example, in one embodiment, the protective garment comprises a glove. The glove includes a hollow member defining an opening for receiving a hand. The hollow member is made from an elastic laminate. The elastic laminate may comprise at least one nonwoven web. The hollow member further includes an elastomeric coating that covers at least a portion of the hollow member. In one embodiment, for instance, the elastomeric coating covers a palm portion and finger portions of the glove.
摘要翻译: 公开了一种聚合物涂覆的防护服。 衣服可以被配置成围绕佩戴者的手臂,腿,脚或手。 例如,在一个实施例中,防护服包括手套。 手套包括限定用于接收手的开口的中空构件。 中空构件由弹性层压体制成。 弹性层压材料可以包括至少一个非织造纤维网。 中空构件还包括覆盖中空构件的至少一部分的弹性体涂层。 在一个实施例中,例如,弹性体涂层覆盖手套的手掌部分和手指部分。
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公开(公告)号:US20060246597A1
公开(公告)日:2006-11-02
申请号:US11119394
申请日:2005-04-29
申请人: Shawn Feaster , Kaiyuan Yang
发明人: Shawn Feaster , Kaiyuan Yang
IPC分类号: G01N31/22
CPC分类号: G01N33/558 , G01N33/52
摘要: A method for controlling fluid flow in an assay device that employs a membrane is provided. Specifically, one or more recessed regions are formed in the membrane by applying a solvent treatment thereto. The solvent treatment is selected based on its particular dissolving capacity for the material used to form the membrane. For example, an alcohol-based solvent, such as methanol, may be used as a solvent for nitrocellulose membranes. Upon contact with the solvent treatment, a recessed region is formed that may serve a variety of different functions relating to flow control. In one particular embodiment, the recessed region may function as a metering channel that is capable of delivering a controlled volume of the test sample to a detection zone upon initiation of the assay.
摘要翻译: 提供了一种用于控制采用膜的测定装置中的流体流动的方法。 具体地,通过对膜进行溶剂处理,在膜中形成一个或多个凹陷区域。 基于其用于形成膜的材料的特定溶解能力来选择溶剂处理。 例如,醇类溶剂如甲醇可用作硝酸纤维素膜的溶剂。 在与溶剂处理接触时,形成可以用于与流量控制有关的各种不同功能的凹陷区域。 在一个具体实施方案中,凹陷区域可用作计量通道,其能够在测定开始时将受控体积的测试样品递送到检测区域。
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公开(公告)号:US07012169B2
公开(公告)日:2006-03-14
申请号:US09826371
申请日:2001-04-04
申请人: Jason P. McDevitt , Michael S. Brunner , Kaiyuan Yang , Jark Lau , John Metz
发明人: Jason P. McDevitt , Michael S. Brunner , Kaiyuan Yang , Jark Lau , John Metz
IPC分类号: A61F13/00
CPC分类号: B32B7/02 , A41D13/087 , A46B5/04 , A61F13/10 , A61F13/105
摘要: A device that can be used to treat appendage ailments is provided. The device, or appendage sleeve, can be used for wounds, cuts, and blisters, as well as joint related ailments, such as arthritis and carpal tunnel syndrome. In some instances, the appendage sleeve can at least partially made from an elastomeric material, such as an elastomeric nonwoven, so that the sleeve can more aptly fit onto a finger or toe. Furthermore, the sleeve can also possess a barrier that is liquid impermeable, but vapor permeable so that the finger or toe of a user is more comfortable. Various additives can be applied to the sleeve to aid for therapeutic purposes.
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公开(公告)号:US20050127578A1
公开(公告)日:2005-06-16
申请号:US10732965
申请日:2003-12-11
申请人: Thomas Triebes , Kaiyuan Yang , Martin Shamis , Sanford White , Vicky Smith
发明人: Thomas Triebes , Kaiyuan Yang , Martin Shamis , Sanford White , Vicky Smith
CPC分类号: B29C70/305 , B29C41/14 , B29K2105/06 , B29L2031/4864 , B29L2031/7538
摘要: A process for manufacturing a fiber reinforced elastomeric article is provided. The process contemplates depositing a plurality of fibers onto a former and dipping the former into a polymer bath containing an elastomeric material to create a fiber reinforced elastomeric article. Depending upon the fibers selected, the fibers may be applied to a dry former or onto a former coated with a tacky surface such as a still wet elastomeric polymer.
摘要翻译: 提供了一种制造纤维增强弹性制品的方法。 该方法考虑将多个纤维沉积到前者上并将前者浸入含有弹性体材料的聚合物浴中以产生纤维增强的弹性制品。 根据所选择的纤维,纤维可以施加到干燥的成型机上或涂覆在涂覆有粘性表面的前体,例如仍然是湿的弹性体聚合物上。
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