公开(公告)号：US09031636B2

公开(公告)日：2015-05-12

申请号：US13781117

申请日：2013-02-28

Applicant: MRI Interventions, Inc.

Inventor： Peter Piferi

IPC: A61B5/055 ,  A61B5/00 ,  A61B5/05

CPC classification number: A61B5/0555 ,  A61B5/6814

Abstract: An MRI-compatible base is configured to support an MRI-compatible head support frame. The base is configured to be secured to a gantry associated with an MRI scanner, and to extend across a width of the gantry. The base allows the head support frame to be moved to any of a plurality of locations across the width of the gantry, and allows the head support frame to rotate about two orthogonal axes so as to be positioned at any of a plurality of angles relative to the gantry.

Abstract translation: MRI兼容基座被配置为支持与MRI兼容的头部支撑框架。 基座被配置为固定到与MRI扫描仪相关联的台架并且跨越台架的宽度延伸。 基座允许头部支撑框架跨过台架的宽度移动到多个位置中的任何一个位置，并且允许头部支撑框架围绕两个正交轴线旋转，以便相对于多个角度 龙门架

公开(公告)号：US20130245741A1

公开(公告)日：2013-09-19

申请号：US13872726

申请日：2013-04-29

Applicant: BOSTON SCIENTIFIC NEUROMODULATION CORPORATION ,  MRI INTERVENTIONS, INC.

Inventor： Ergin Atalar ,  Justin Allen ,  Paul Bottomley ,  William Edelstein ,  Parag V. Kamarkar

IPC: A61N1/06

CPC classification number: A61N1/06 ,  A61N1/056 ,  A61N1/086

Abstract: Some embodiments are directed to MRI/RF compatible medical interventional devices. A plurality of spaced apart high impedance circuit segments are configured to have a high Impedance at a high range of radiofrequencies and a low impedance at a low range of frequencies. The high impedance circuit segments may comprise co-wound coiled inductors and can reduce, block or inhibit RJ-transmission along the lead system (20) during exposure to RF associated with a high-Held magnet MRI systems, while permuting passage of low frequency physiologic signals, treatments and/or stimuli. The devices can include at least one electrode.

Abstract translation: 一些实施例涉及MRI / RF兼容医疗介入装置。 多个间隔开的高阻抗电路段被配置为在高频范围内具有高阻抗，并且在低频率范围内具有低阻抗。 高阻抗电路段可以包括共绕线圈电感器，并且可以在暴露于与高磁铁磁共振系统相关联的RF期间沿着引导系统（20）减少，阻止或抑制RJ-传输，同时置换低频生理 信号，治疗和/或刺激。 该装置可以包括至少一个电极。

公开(公告)号：US20130131496A1

公开(公告)日：2013-05-23

申请号：US13749351

申请日：2013-01-24

Applicant: MRI Interventions, Inc.

Inventor： Kimble L. Jenkins ,  Peter Piferi ,  Kamal Vij ,  Daniele Ghidoli ,  Jesse Flores ,  Parag V. Karmarkar ,  Rajesh Pandey

IPC: A61B5/06 ,  A61B5/00 ,  A61B5/053 ,  A61B18/02 ,  A61M25/01 ,  A61M5/00 ,  A61B5/055 ,  A61B18/18

CPC classification number: A61B5/062 ,  A61B5/0044 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/053 ,  A61B5/055 ,  A61B5/065 ,  A61B5/415 ,  A61B5/418 ,  A61B18/02 ,  A61B18/18 ,  A61B34/10 ,  A61B34/20 ,  A61B2090/365 ,  A61B2090/374 ,  A61B2090/3954 ,  A61M5/00 ,  A61M25/01 ,  A61M25/0127 ,  A61M29/00 ,  A61M2025/0089 ,  A61M2025/0166 ,  A61M2025/0681 ,  A61M2025/09175 ,  G01R33/286 ,  G01R33/287

Abstract: An MRI-compatible catheter that reduces localized heating due to MR scanner-induced currents includes an elongated flexible shaft having a distal end portion and an opposite proximal end portion. A handle is attached to the proximal end portion and includes an electrical connector interface configured to be in electrical communication with an MRI scanner. One or more RF tracking coils are positioned adjacent the distal end portion of the shaft. Each RF tracking coil includes a conductive lead, such as a coaxial cable, that extends between the RF tracking coil and the electrical connector interface and electrically connects the RF tracking coil to an MRI scanner. In some embodiments of the present invention, the conductive lead has a length sufficient to define an odd harmonic/multiple of a quarter wavelength of the operational frequency of the MRI Scanner, and/or includes a series of pre-formed back and forth segments along its length.

Abstract translation: 减少由于MR扫描器感应电流引起的局部加热的MRI兼容导管包括具有远端部分和相对近端部分的细长柔性轴。 手柄附接到近端部分并且包括被配置为与MRI扫描仪电连通的电连接器接口。 一个或多个RF跟踪线圈定位在轴的远端部分附近。 每个RF跟踪线圈包括在RF跟踪线圈和电连接器接口之间延伸的导电引线，例如同轴电缆，并将RF跟踪线圈电连接到MRI扫描器。 在本发明的一些实施例中，导电引线具有足以限定MRI扫描器的工作频率的四分之一波长的奇次谐波/倍数的长度，和/或包括一系列预先形成的前后段 它的长度。

公开(公告)号：US09891296B2

公开(公告)日：2018-02-13

申请号：US14468922

申请日：2014-08-26

Applicant: MRI Interventions, Inc.

Inventor： Peter Piferi

IPC: G01R33/28 ,  A61M5/158 ,  A61B10/02 ,  A61B5/055 ,  G01R33/34 ,  A61M39/02

CPC classification number: G01R33/286 ,  A61B5/055 ,  A61B10/0233 ,  A61M5/158 ,  A61M2039/025 ,  A61M2205/0211 ,  A61M2205/0227 ,  A61M2210/0687 ,  A61M2210/0693 ,  G01R33/287 ,  G01R33/34084

Abstract: Devices, kits, assemblies systems and methods for transferring fluid to or from a subject include an elongate guide cannula having opposing proximal and distal ends with an open axially extending lumen. The proximal end includes a connector. The devices also include an elongate needle having opposing proximal and distal ends, the needle having a connector that is configured to attach to the guide cannula connector and is attached to or attachable to a length of flexible tubing, wherein the elongate needle is configured to be slidably inserted into the guide cannula lumen so that the distal end of the needle extends out of the distal end of the distal end of the guide cannula a suitable distance.

公开(公告)号：US09630000B2

公开(公告)日：2017-04-25

申请号：US15012692

申请日：2016-02-01

Applicant: Boston Scientific Neuromodulation Corporation ,  MRI Interventions, Inc.

Inventor： Paul A. Bottomley ,  Parag V. Karmarkar ,  Justin M. Allen ,  William A. Edelstein ,  Peter Piferi ,  Brian Gore

IPC: A61N1/05 ,  A61N1/08 ,  A61N1/04 ,  B29C33/12 ,  G01N3/32 ,  B29L31/00

CPC classification number: A61N1/08 ,  A61N1/0488 ,  A61N1/05 ,  A61N1/086 ,  B29C33/126 ,  B29L2031/753 ,  G01N3/32 ,  Y10T29/49071

Abstract: MRI/RF compatible leads include at least one conductor, a respective conductor having at least one segment with a multi-layer stacked coil configuration. The lead can be configured so that the lead heats local tissue less than about 10 degrees Celsius (typically about 5 degrees Celsius or less) or does not heat local tissue when a patient is exposed to target RF frequencies at a peak input SAR of at least about 4 W/kg and/or a whole body average SAR of at least about 2 W/kg. Related leads and methods of fabricating leads are also described.

公开(公告)号：US09572928B2

公开(公告)日：2017-02-21

申请号：US14204378

申请日：2014-03-11

Applicant: MRI Interventions, Inc.

Inventor： J. Michael Shifflette ,  Peter Piferi

IPC: A61M37/00 ,  A61M5/145 ,  A61M25/02

CPC classification number: A61M5/14593 ,  A61B90/11 ,  A61M5/14526 ,  A61M25/02 ,  A61M2005/14513

Abstract: A substance delivery device includes an elongated tubular body having opposing proximal and distal ends, and a diaphragm that is in slideable sealing engagement with an inside wall of the tubular body. The diaphragm is movable in opposite first and second directions within the tubular body. A substance is contained within the tubular body between the diaphragm and the tubular body distal end, and a slave fluid is contained within the tubular body between the diaphragm and the tubular body proximal end. When pressure is exerted on the slave fluid, the slave fluid causes the diaphragm to move and eject the substance through the tubular body distal end.

Abstract translation: 物质输送装置包括具有相对的近端和远端的细长管状体，以及与管状体的内壁可滑动地密封接合的隔膜。 隔膜可在管状体内相对的第一和第二方向移动。 物质被包含在隔膜和管状体远端之间的管状体内，并且从动液容纳在隔膜和管状体近端之间的管状体内。 当从动液体施加压力时，从动液体使膜片移动并通过管状体远端排出物质。

公开(公告)号：US20160256069A1

公开(公告)日：2016-09-08

申请号：US15067615

申请日：2016-03-11

Applicant: MRI Interventions, Inc.

Inventor： Kimble Jenkins ,  Peter Piferi ,  Philip Bradley Hotte ,  Pavel Farberov ,  Timothy Neil Orr ,  Paul Arthur Geiger ,  David John Sayler

IPC: A61B5/055 ,  A61B90/00 ,  A61B34/00 ,  A61B5/00 ,  A61B34/10

CPC classification number: A61B34/74 ,  A61B5/0042 ,  A61B5/055 ,  A61B5/0555 ,  A61B5/7435 ,  A61B34/10 ,  A61B34/25 ,  A61B90/11 ,  A61B90/14 ,  A61B90/361 ,  A61B90/37 ,  A61B90/96 ,  A61B2017/00212 ,  A61B2017/3407 ,  A61B2017/3409 ,  A61B2034/101 ,  A61B2034/107 ,  A61B2034/252 ,  A61B2034/254 ,  A61B2034/256 ,  A61B2090/103 ,  A61B2090/374 ,  A61B2090/3933 ,  A61B2090/3937 ,  A61B2090/395 ,  A61B2090/3954 ,  A61B2090/3983 ,  G01R33/286 ,  G01R33/3415 ,  G01R33/546

Abstract: Circuits and computer program products onboard and/or adapted to communicate with an scanner that electronically recognize predefined physical characteristics of the at least one tool to automatically segment image data provided by the scanner whereby the at least one tool constitutes a point of interface with the system. The circuits and computer program products are configured to provide a User Interface that defines workflow progression for an image guided surgical procedure and allows a user to select steps in the workflow, and generate multi-dimensional visualizations using the predefined data of the at least one tool and data from images of the patient in substantially real time during the surgical procedure.

Abstract translation: 板上和/或适于与扫描器通信的电路和计算机程序产品，其电子地识别所述至少一个工具的预定义的物理特性，以自动分割由扫描器提供的图像数据，由此所述至少一个工具构成与系统的接口点 。 电路和计算机程序产品被配置为提供定义用于图像引导的外科手术的工作流程的用户界面，并且允许用户选择工作流中的步骤，并使用至少一个工具的预定义数据生成多维可视化 以及在外科手术期间实质上实时地来自患者的图像的数据。

公开(公告)号：US20160220812A1

公开(公告)日：2016-08-04

申请号：US15012692

申请日：2016-02-01

Applicant: Boston Scientific Neuromodulation Corporation ,  MRI Interventions, Inc.

Inventor： Paul A. Bottomley ,  Parag V. Karmarkar ,  Justin M. Allen ,  William A. Edelstein ,  Peter Piferi ,  Brian Gore

IPC: A61N1/08 ,  A61N1/05

CPC classification number: A61N1/08 ,  A61N1/0488 ,  A61N1/05 ,  A61N1/086 ,  B29C33/126 ,  B29L2031/753 ,  G01N3/32 ,  Y10T29/49071

Abstract: MRI/RF compatible leads include at least one conductor, a respective conductor having at least one segment with a multi-layer stacked coil configuration. The lead can be configured so that the lead heats local tissue less than about 10 degrees Celsius (typically about 5 degrees Celsius or less) or does not heat local tissue when a patient is exposed to target RF frequencies at a peak input SAR of at least about 4 W/kg and/or a whole body average SAR of at least about 2 W/kg. Related leads and methods of fabricating leads are also described.

Abstract translation: MRI / RF兼容引线包括至少一个导体，具有至少一个具有多层堆叠线圈配置的段的相应导体。 引线可以被配置为使得铅在局部组织中加热小于约10摄氏度（通常约5摄氏度或更低），或者当患者暴露于至少峰值输入SAR的目标RF频率时不加热局部组织 约4W / kg和/或全身平均SAR至少约2W / kg。 还描述了制造引线的相关引线和方法。

公开(公告)号：US09386941B2

公开(公告)日：2016-07-12

申请号：US14290051

申请日：2014-05-29

Applicant: MRI Interventions, Inc.

Inventor： Peter Piferi ,  Kamal Vij ,  Scott Arnold

IPC: A61B5/055 ,  A61B6/04

CPC classification number: A61B5/0555 ,  A61B6/0407

Abstract: Scanner Systems with table stabilizers for stabilizing patient support structures during a surgery include a stabilizer block that can cooperate with the gantry to structurally support a head end portion of the table to prevent undesired movement of the table under an end load.

Abstract translation: 具有用于在手术期间稳定患者支撑结构的台面稳定器的扫描仪系统包括可与机架配合的稳定器块，以结构地支撑工作台的头端部分，以防止工作台在端部负载下的不期望的移动。

公开(公告)号：US09383421B2

公开(公告)日：2016-07-05

申请号：US13796485

申请日：2013-03-12

Applicant: MRI Interventions, Inc.

Inventor： Kamal Vij

IPC: G01R33/28 ,  A61B5/00 ,  A61B5/055 ,  A61B5/06 ,  A61B18/14 ,  A61B18/00 ,  A61B17/00

CPC classification number: G01R33/287 ,  A61B5/055 ,  A61B5/062 ,  A61B5/6852 ,  A61B18/1492 ,  A61B2017/00088 ,  A61B2018/00577 ,  A61B2034/2051 ,  A61B2090/3954 ,  A61B2562/043

Abstract: An MRI-compatible intrabody device includes an elongated flexible shaft having a distal end portion, an opposite proximal end portion, an electrical connector interface configured to be in electrical communication with an MRI scanner, and a tracking coil assembly adjacent the shaft distal end portion. The tracking coil assembly includes a first spool having opposing first and second end walls and a second spool having opposing third and fourth end walls. The second spool is in end-to-end relationship with the first spool such that the second and third end walls are in adjacent, spaced-apart relationship. A tracking coil is wound around the first spool, and a coaxial cable is wound around the second spool. An outer conductor of the coaxial cable is connected to one end of the tracking coil and the inner conductor of the coaxial cable is connected to an opposite end of the tracking coil.

Abstract translation: MRI兼容的体内装置包括细长的柔性轴，其具有远端部分，相对的近端部分，被配置为与MRI扫描仪电连通的电连接器接口以及邻近所述轴远端部分的跟踪线圈组件。 跟踪线圈组件包括具有相对的第一和第二端壁的第一线轴和具有相对的第三和第四端壁的第二线轴。 第二阀芯与第一阀芯处于端对端关系，使得第二和第三端壁处于相邻的间隔关系。 跟踪线圈缠绕在第一线轴上，并且同轴电缆缠绕在第二线轴上。 同轴电缆的外导体连接到跟踪线圈的一端，并且同轴电缆的内导体连接到跟踪线圈的相对端。