Abstract:
A slave device may be configured to receive at least one bus interface clock and bus interface signals from a bus coupled to the at least one bus interface unit. The slave device may also be configured to operate independently of at least one main function clock
Abstract:
The present invention relates to an immunoregulating agent comprising a peptide, a pharmaceutical composition and a method of preventing or treating immune-related disorder such as sever sepsis or acute respiratory distress syndrome (ARDS), and the use of peptide for anti-inflammatory agent, an antibacterial agent, or an inhibiting agent of an immune cell apoptosis.
Abstract:
A semantic-based searching apparatus and method which can search for desired information from various types of media using associative properties of search target objects are provided. The semantic-based searching apparatus stores an associative search structure that previously stores a semantic index. The associative search structure is to obtain a final search object corresponding to an input search query. The semantic index configuration includes feature metadata used to identify a specific object, semantic entity metadata to indicate semantic entities corresponding to the feature metadata, and semantic relation metadata to indicate a relation between the semantic entities. The semantic-based searching apparatus uses semantic metadata stored in conformity with the semantic index configuration, the semantic index, and the associative search structure to generate a search result corresponding to the input search query.
Abstract:
The present invention relates to a method and detection kit for determining a presence of one or more proteins using aptamer-mediated pull-down assays. Specifically, a reproducible a protein precipitation (Co-AP/AP) method is provided to identify physiologically relevant protein-protein interactions by using target protein-specific aptamers, and to confirm its superior performance over antibody based protein precipitation (Co-IP/IP) methods in terms of its protein pull-down performance.
Abstract translation:本发明涉及一种用于使用适体介导的下拉测定来测定一种或多种蛋白质的存在的方法和检测试剂盒。 具体来说,提供了可重复的蛋白沉淀(Co-AP / AP)方法,通过使用靶蛋白特异性适体来鉴定与生物相关的蛋白质 - 蛋白质相互作用,并确认其优于基于抗体的蛋白质沉淀(Co-IP / IP )方法在其蛋白质下拉性能方面。
Abstract:
This disclosure relates to an angiogenesis-related pharmaceutical composition using connective tissue growth factor, more particularly to a pharmaceutical composition for promoting angiogenesis containing the connective tissue growth factor or a pharmaceutical composition for inhibiting angiogenesis containing at least one selected from the group consisting of polypeptide, antibody and a compound binding to connective tissue growth factor. The fragment of connective tissue growth factor protein, which was found out in the present invention, is a binding region to FPRL1, effectively induces FPRL1-specific ERK phosphorylation, activates FPRL1 to increase intracellular Ca2+ concentration, and finally, effectively induces angiogenesis, and thus, the fragment of connective tissue growth factor may be useful for a pharmaceutical composition for promoting angiogenesis, while polypeptide, antibody or a compound binding to the fragment of connective tissue growth factor protein may be useful for a pharmaceutical composition for inhibiting angiogenesis.
Abstract:
The present invention provides methods for identifying the plurality of aptamers that bind to different sites of a target molecule and methods for using the same, for example, in sandwich assays. In particular, the plurality of aptamers binding to different sites of the target molecules is identified from a library of aptamers identified from the same SELEX process.
Abstract:
An apparatus and method for providing a terminal web service capable of being associated with data and/or native operations of a terminal while using a rich internet application are provided. The terminal apparatus includes a web application providing unit and a terminal web service providing unit. The web application providing unit discovers a terminal web service control script, which performs control to achieve association with respect to a terminal web service provided by the terminal apparatus, by executing a client script received from an external web server and to generate a hypertext transport protocol (HTTP) request message for requesting the terminal web service by use of the terminal web service control script. The terminal web service providing unit is configured to, upon reception of the HTTP request message, provide the terminal web service by sending the web application providing unit a HTTP reply message for providing reply information by the terminal web service.
Abstract:
Improved G-rich oligonucleotide (GRO) aptamers specific to nucleolin, a method of preparing the aptamers, and a use of the aptamers for diagnosing and/or treating a nucleolin-associated disease, are provided.
Abstract:
The present invention relates to a ligand to regulate immune response, i.e., PACAP27 which is one of pituitary adenylate cyclase-activating polypeptides and Serum amyloid A (SAA), and their novel use in treating or preventing diseases associated with immune response. More specifically, the present invention relates to a complex of PACAP27-FPRL1 having a regulatory effect on immune response, and a use thereof in regulating immune response. In another aspect, the present invention relates to a complex of SAA and FPRL1, and a use thereof in inhibiting synoviocyte hyperplasia and angiogenesis and treating or preventing inflammatory diseases including Rheumatoid arthritis (RA).
Abstract:
A method for preparing amino linker oligonucleotides is provided, wherein an amino protecting group is efficiently removed from the amino linker oligonucleotides protected by the protecting group, and thereby achieving a high yield of the amino linker oligonucleotides.