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21.发明申请Medicated coatings for implantable medical devices including polyacrylates 有权用于可植入医疗器械的药物涂层，包括聚丙烯酸酯公开(公告)号：US20060062824A1
公开(公告)日：2006-03-23
申请号：US10948036
申请日：2004-09-22
Applicant: Stephen Pacetti , Thierry Glauser
Inventor： Stephen Pacetti , Thierry Glauser
IPC: A61F2/00
CPC classification number: A61L31/16 , A61L31/10 , A61L2300/00 , C08L33/10
Abstract: A polymer for a medical device, particularly for a drug eluting stent, is described. The polymer can be derived from n-butyl methacrylate and can have a degree of an elongation at failure from about 20% to about 500%
Abstract translation: 描述了用于医疗装置的聚合物，特别是用于药物洗脱支架的聚合物。 聚合物可以衍生自甲基丙烯酸正丁酯，并且可以具有约20％至约500％的失效伸长率，
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公开(公告)号：US20060062821A1
公开(公告)日：2006-03-23
申请号：US11218654
申请日：2005-09-02
Applicant: Murthy Simhambhatla , Ni Ding , Stephen Pacetti
Inventor： Murthy Simhambhatla , Ni Ding , Stephen Pacetti
IPC: A61F13/00
CPC classification number: A61L31/10 , A61L31/16 , A61L2300/114 , A61L2300/606 , A61L2300/622 , A61L2300/626 , C08L77/04
Abstract: Polycationic peptide coatings for implantable medical devices and methods of making the same are described. The methods include applying an emulsion on the device, the emulsion including a polymer and a polycationic peptide. Other methods include incorporation of the polycationic peptide in microspheres and liposomes.
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23.发明申请Compositions containing fast-leaching plasticizers for improved performance of medical devices 有权含有快速浸出增塑剂的组合物可改善医疗器械的性能公开(公告)号：US20060058868A1
公开(公告)日：2006-03-16
申请号：US10937975
申请日：2004-09-10
Applicant: David Gale , Klaus Kleine , Anthony Abbate , Svava Atladottir , Stephen Pacetti
Inventor： David Gale , Klaus Kleine , Anthony Abbate , Svava Atladottir , Stephen Pacetti
CPC classification number: A61L31/141
Abstract: Medical implants containing a temporary plasticizer, methods of producing such implants, and methods of using the implants in treating a disease, or ameliorating one or more symptoms thereof, in a subject are provided.
Abstract translation: 提供了包含临时增塑剂的医疗植入物，生产这种植入物的方法，以及使用植入物治疗疾病或改善其一种或多种症状的方法。
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公开(公告)号：US20050271700A1
公开(公告)日：2005-12-08
申请号：US10750139
申请日：2004-06-03
Applicant: Jessica DesNoyer , Syed Hossainy , Stephen Pacetti , Yiwen Tang
Inventor： Jessica DesNoyer , Syed Hossainy , Stephen Pacetti , Yiwen Tang
IPC: A61F2/00 , A61L2/00 , A61L31/10 , A61L31/16 , C09D177/12 , C09D187/00
CPC classification number: A61L31/16 , A61L31/10 , A61L2300/602 , C08L77/12
Abstract: A poly(ester amide) (PEA) coating with enhanced mechanical and/or release rate for coating an implantable device, such as a drug-eluting stent, is disclosed. A method of forming the PEA coating onto a device and a method of treating a disorder, such as restenosis, are also disclosed.
Abstract translation: 公开了用于涂覆可植入装置（例如药物洗脱支架）的具有增强的机械和/或释放速率的聚（酯酰胺）（PEA）涂层。 还公开了将PEA涂层形成在器件上的方法和治疗诸如再狭窄的病症的方法。
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25.发明申请Barriers for polymer-coated implantable medical devices and methods for making the same 有权聚合物涂覆的可植入医疗器械的障碍物及其制造方法公开(公告)号：US20050208098A1
公开(公告)日：2005-09-22
申请号：US11132048
申请日：2005-05-17
Applicant: Daniel Castro , Stephen Pacetti
Inventor： Daniel Castro , Stephen Pacetti
IPC: A61F2/02 , A61F2/82 , A61F2/86 , A61L27/30 , A61L27/34 , A61L27/56 , A61L31/08 , A61L31/10 , A61L31/16 , A61F2/06
CPC classification number: A61F2/82 , A61F2/86 , A61F2250/0067 , A61F2310/0097 , A61L27/306 , A61L27/34 , A61L27/56 , A61L31/088 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2420/08 , C08L31/04 , C08L33/10
Abstract: A drug eluting medical device is disclosed. The device includes a barrier layer for reducing the rate of release of a drug.
Abstract translation: 公开了药物洗脱医疗装置。 该装置包括用于降低药物释放速率的阻挡层。
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Patent Agency Ranking
公开(公告)号：US20050143808A1
公开(公告)日：2005-06-30
申请号：US11067375
申请日：2005-02-25
Applicant: Syed Hossainy , Yiwen Tang , Andrew Tung , Stephen Pacetti
Inventor： Syed Hossainy , Yiwen Tang , Andrew Tung , Stephen Pacetti
CPC classification number: A61F2/06 , A61F2/0077 , A61F2250/0067 , Y10T428/13 , Y10T428/24942 , Y10T428/3154 , Y10T428/31786 , Y10T428/31855 , Y10T428/31935
Abstract: An implantable medical device, such as a stent, is disclosed having a coating. The coating includes a poly(butylene terephthalate-co-ethylene glycol) polymer. The coating can also include a drug.
Abstract translation: 公开了一种具有涂层的可植入医疗装置，例如支架。 涂层包括聚（对苯二甲酸丁二醇酯 - 共 - 乙二醇）聚合物。 涂层还可以包括药物。
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27.发明申请公开(公告)号：US20050142202A1
公开(公告)日：2005-06-30
申请号：US11015943
申请日：2004-12-17
Applicant: Wouter Roorda , Stephen Pacetti
Inventor： Wouter Roorda , Stephen Pacetti
IPC: A61K9/16 , A61K31/727 , A61K48/00 , A61K9/14 , A61K38/18
CPC classification number: A61K9/14 , A61K9/1617 , A61K9/1647 , A61K9/1658 , A61K9/1694 , A61K31/573 , A61K31/727 , A61K38/1825 , A61K47/26 , A61K47/36 , A61K48/00
Abstract: Compositions and methods of using the compositions to achieve a therapeutic effect are provided.
Abstract translation: 提供了使组合物达到治疗效果的组合物和方法。
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28.发明申请Coatings for implantable devices including biologically erodable polyesters and methods for fabricating the same 有权用于可植入装置的涂层，包括生物可侵蚀的聚酯及其制造方法公开(公告)号：US20050112171A1
公开(公告)日：2005-05-26
申请号：US10719516
申请日：2003-11-21
Applicant: Yiwen Tang , Stephen Pacetti
Inventor： Yiwen Tang , Stephen Pacetti
CPC classification number: A61L31/16 , A61F2/86 , A61L31/10 , A61L31/148 , A61L2300/606 , A61L2420/08 , C08L67/04
Abstract: A medical article comprising an implantable substrate having a coating is disclosed, the coating comprising a biologically erodable polymer having the glass transition temperature below about −50° C. The biologically erodable polymer can be blended with a polymeric additive which either has the glass transition temperature of about −50° C. or higher, or a degree of crystallinity greater than that of the first polymer.
Abstract translation: 公开了包含具有涂层的可植入基材的医疗制品，所述涂层包含玻璃化转变温度低于约-50℃的生物侵蚀性聚合物。可生物侵蚀的聚合物可与聚合物添加剂共混，所述聚合物添加剂具有玻璃化转变温度 约-50℃或更高，或结晶度大于第一聚合物的结晶度。
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29.发明申请Coatings for implantable devices comprising polymers of lactic acid and methods for fabricating the same 审中-公开用于包含乳酸聚合物的可植入装置的涂层及其制造方法公开(公告)号：US20050112170A1
公开(公告)日：2005-05-26
申请号：US10718976
申请日：2003-11-20
Applicant: Syed Hossainy , Yiwen Tang , Eugene Michal , Thierry Glauser , Stephen Pacetti , Jessica DesNoyer
Inventor： Syed Hossainy , Yiwen Tang , Eugene Michal , Thierry Glauser , Stephen Pacetti , Jessica DesNoyer
IPC: A61F2/00 , A61F2/86 , A61L29/08 , A61L29/16 , A61L31/10 , A61L31/14 , A61L31/16 , A61L33/06 , A61M29/02
CPC classification number: A61L31/10 , A61F2/86 , A61F2250/0067 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2300/606 , C08L67/04
Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising polymers of lactic acid.
Abstract translation: 公开了用于可植入医疗装置的涂层及其制造方法，所述涂层包含乳酸聚合物。
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30.发明授权公开(公告)号：US08870847B2
公开(公告)日：2014-10-28
申请号：US13079239
申请日：2011-04-04
Applicant: Dariush Davalian , Stephen Pacetti , Florian Niklas Ludwig , Syed Faiyaz Ahmed Hossainy , Irina Astafieva , Kimchi Tran
Inventor： Dariush Davalian , Stephen Pacetti , Florian Niklas Ludwig , Syed Faiyaz Ahmed Hossainy , Irina Astafieva , Kimchi Tran
CPC classification number: A61K9/0019 , A61F2/95 , A61L29/16 , A61L31/16 , A61L2300/416 , A61L2300/62 , A61M25/0084 , A61M25/104 , A61M2025/105
Abstract: This invention is directed to a method of treating a vascular disease involving administration to a patient by means of an angioplasty balloon a composition comprising a permeability-enhancing substance and a therapeutic agent.
Abstract translation: 本发明涉及一种治疗血管疾病的方法，所述血管疾病涉及通过血管成形术球囊向患者施用包含渗透性增强物质和治疗剂的组合物。
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