Abstract:
An object is to provide a novel therapeutic drug for adult T-cell leukemia having an ATL cell specific antitumor effect. The therapeutic drug for adult T-cell leukemia according to the invention is characterized by containing a compound represented by the formula I or a prodrug thereof, wherein R1 is H, OH, an alkoxy group, an acyl group, or a thioacyl group, R2 is an acyl group, a thioacyl group, CONR7R8, or CSNR7R8 (R7 and R8 being each independently H, an alkyl group containing 1 to 3 carbon atoms, or a phenyl group), or R1 and R2 together may form a ring, X1 and X2 may be the same or different and are each —CR3R4—, —SiR3R4— or oxygen, and R3 and R4 may be the same or different and are each an alkyl group containing 1 to 6 carbon atoms.
Abstract translation:目的是提供一种具有ATL细胞特异性抗肿瘤作用的成人T细胞白血病的新型治疗药物。 根据本发明的成人T细胞白血病的治疗药物的特征在于含有式I化合物或其前体药物,其中R1是H,OH,烷氧基,酰基或硫代酰基,R2 是酰基,硫代酰基,CONR7R8或CSNR7R8(R7和R8各自独立地为H,含有1至3个碳原子的烷基或苯基),或者R1和R2一起可以形成环,X1和 X2可以相同或不同,各自为-CR 3 R 4 - , - SiR 3 R 4 - 或氧,R 3和R 4可以相同或不同,并且各自为含有1至6个碳原子的烷基。
Abstract:
The present invention relates to an anti-viral agent comprising a compound represented by the following formula (I): (wherein X represents CH, a nitrogen atom, an oxygen atom, or a sulfur atom; Y and Z are the same or different and each represents a nitrogen atom or C—R8, and at least one of them represents a nitrogen atom; R1 to R8 are the same or different and each represents a hydrogen atom, a linear C1-10-hydrocarbon group, a hydroxy group, or a substituted or unsubstituted benzyl group; and, when X represents an oxygen atom or a sulfur atom, R5 is absent), or the following formula (II): (wherein X′ represents CH or a nitrogen atom; Y′ and Z′ are the same or different and each represents a nitrogen atom or N—R9, or C—R8 and at least one of them represents a nitrogen atom or N—R9; R1 to R4 and R6 to R8 are as defined above; R9 represents a hydrogen atom, a linear C1-10-hydrocarbon group, a hydroxy group, or a substituted or unsubstituted benzyl group; and, the C ring has the maximum number of double bonds at the dotted line portion) or a pharmaceutically acceptable salt thereof.
Abstract translation:本发明涉及包含由下式(I)表示的化合物的抗病毒剂:(其中X表示CH,氮原子,氧原子或硫原子; Y和Z相同或不同, 各自表示氮原子或C-R8,并且其中至少一个表示氮原子; R 1〜R 8相同或不同,表示氢原子,直链C 1-10烃基,羟基或 取代或未取代的苄基;当X表示氧原子或硫原子时,R 5不存在)或下式(II)表示:(其中X'表示CH或氮原子,Y'和Z'为 相同或不同,各自表示氮原子或N-R9或C-R8,并且其中至少一个表示氮原子或N-R 9; R 1至R 4和R 6至R 8如上所定义; R 9表示氢 原子,直链C 1-10烃基,羟基或取代或未取代的苄基;和C环h 作为虚线部分的双键的最大数目)或其药学上可接受的盐。
Abstract:
Data is read from a recording medium and the reproduced data is deinterleaved and stored to a first memory while input/output to/from the first memory is arbitrated. It is determined whether a predetermined number of data units is stored to the first memory. Based on the result data, it is determined whether transfer of the data stored in first memory to a second memory is permitted. If data transfer is permitted, the reproduced data is transferred from the first memory to the second memory, during which time input/output to/from the second memory is arbitrated. The reproduced data stored to the second memory is then error corrected, and user data contained in the error corrected reproduction data is externally output from the second memory.
Abstract:
The invention provides a method for easily and promptly erasing an image (including a character) formed on a printed article, and an apparatus employing such method. A printed article bearing an image formed on a surface including an inorganic pigment is exposed to a reactive gas, generated by creeping discharge or corona discharge induced by a voltage application between a pair of opposed electrodes, whereby the image is erased.
Abstract:
An exposure apparatus performs exposure of a photosensitive body by an array of light emitting devices to form an image as a latent image thereon. The array of light emitting devices incorporate micro-optical cavities. The micro-optical cavities limit wavelengths of light emitted from the array of light emitting devices, so that the wavelength at a peak of emitted light is in a half width region of sensitivity versus wavelength of the photosensitive body.
Abstract:
An organic luminescent element includes a substrate, an anode, a cathode, at least one organic material layer interposed between the anode and the cathode, and a sealing film containing a ferroelectric material provided on the anode or the cathode on the organic material layer. Preferably, the organic luminescent element further includes a counter electrode provided on the sealing film. Preferably, the substrate is transparent, and the anode is composed of indium tin oxide.
Abstract:
An error correcting apparatus includes a storing means for storing product code with n2 rows and n1 columns, an error correcting unit 5 that performs error correction for four code sequences simultaneously in parallel, and a bus control unit 2 for reading codes on four rows from the buffer memory 1 and transferring the codes to the error correcting unit 5. The bus control unit 2 reads and transfers four consecutive codes on each of four rows in order before shifting the reading position by four codes in the row direction.
Abstract:
An image forming apparatus includes a photosensitive member, an exposure device includes a single-chip light emission element array formed by integrating a plurality of light emitting elements in a single chip which exposure device executes the exposure in the main scanning direction relative to the movement of the photosensitive member, by the light emission from the single-chip light emission element array, and a developing device provided around the photosensitive member.
Abstract:
The present invention provides an electrophotographic photosensitive member having a substrate and a photosensitive layer thereupon, wherein a surface protecting layer of the photosensitive member contains a resin which is obtained by curing a curable organosilicon polymer and an organosilicon-modified positive hole transporting compound; a process-cartridge which has, in addition to the electrophotographic photosensitive member, at least one from among a primary charging means, a developing means, and a cleaning means placed into a housing, and which can be reversibly mounted to an image forming apparatus; and the image forming apparatus using the electrophotographic photosensitive member.
Abstract:
An image forming apparatus has an electrophotographic photosensitive member with a support, a photosensitive layer with a thickness (T), a charging subunit, an exposure subunit, a developing subunit, and a transfer subunit. The exposure subunit illuminates the charged photosensitive member with a light beam having a spot area (S), such that the product S.times.T is 5,000-12,000 .mu.m.sup.3.